| Definition | Actinobacillus pleuropneumoniae serovar 5b str. L20 chromosome, complete genome. |
|---|---|
| Accession | NC_009053 |
| Length | 2,274,482 |
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The map label for this gene is sapF [H]
Identifier: 126208715
GI number: 126208715
Start: 1435370
End: 1436170
Strand: Reverse
Name: sapF [H]
Synonym: APL_1249
Alternate gene names: 126208715
Gene position: 1436170-1435370 (Counterclockwise)
Preceding gene: 126208716
Following gene: 126208714
Centisome position: 63.14
GC content: 42.7
Gene sequence:
>801_bases ATGCCTTTACTTGATATTAAACGTCTGAATAAACATTTTACCGACCGGATCGGTCTGTTTCGTAAGCATGATTTTTATGC GGTAAAAGATGTTTCTTTTACGCTGGAACGGGGCGAAACGATCGCAATTATCGGTGAAAACGGTGCGGGTAAATCGACCT TATCCAAGATGATTGCCGGCATTACCAAGCCTACCTCCGGTGAAATGGTTTTTAAAGGTCAGGCGCTTCATTTCGGCGAT TACCGTTTTCGAGCGAAGCATATTCGGATGATGTTCCAAGATCCGAACGATGCTTTCGATCCGAATTATAATGTCGGTCA AATTTTAGATTCTCCTCTGCGTTTAGCGACAAACCTGAATGAAAGCGAACGTAATGATCGAATTTTCAGTACGCTACGTT TAGTCGGTATGTATCCCGAACACGCTTTAATTCCTATTCGCGAAACTTCGAGCAGCCAAAAGCAACGTATCGCTTTAGCG CGAGCCTTGATTCTTTCTCCGGAAATTATTATTGCCGACGATACGCTAAGTACCTTGGATTTTTCGGTTAAAACGCAGCT CACCAATCTAATGCTTAATTTGCAAGAGCGGTTAGGCATTTCGTTTATCTATGTCGGGCAGCATCTCGGCATTATTAAAC ATATTGCGGATAAACTGATGGTAATGCATGAGGGAGAAGTTATCGAATACGGTTTAACTAAAGACGTCTTGTTAGATCCG CAAAGCCCGATTACAGCACGTTTAATCGAAAGTCATTTCGGCAAAAAATTGACCCCGGAAGCATGGGGCGACTCTTATTA A
Upstream 100 bases:
>100_bases ACTTTAGTAAAAAAGACCGCTTGTTAGCGGTCTTTTTCGTTGATAATTGTATAGGGATAACTGATAATGGTTTTTCCAAA TATTCATATTCAATGATCAA
Downstream 100 bases:
>100_bases AATCAATAAAAAATAATCTGATAAAAATATGCAACACGACGAATTTATACGGGGAATCAAAGAAGTATCCCCGATGATGT TCGGTTTTATTCCTTTAGGC
Product: peptide transport system ATP-binding protein SapF
Products: ADP; phosphate; peptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 266; Mature: 265
Protein sequence:
>266_residues MPLLDIKRLNKHFTDRIGLFRKHDFYAVKDVSFTLERGETIAIIGENGAGKSTLSKMIAGITKPTSGEMVFKGQALHFGD YRFRAKHIRMMFQDPNDAFDPNYNVGQILDSPLRLATNLNESERNDRIFSTLRLVGMYPEHALIPIRETSSSQKQRIALA RALILSPEIIIADDTLSTLDFSVKTQLTNLMLNLQERLGISFIYVGQHLGIIKHIADKLMVMHEGEVIEYGLTKDVLLDP QSPITARLIESHFGKKLTPEAWGDSY
Sequences:
>Translated_266_residues MPLLDIKRLNKHFTDRIGLFRKHDFYAVKDVSFTLERGETIAIIGENGAGKSTLSKMIAGITKPTSGEMVFKGQALHFGD YRFRAKHIRMMFQDPNDAFDPNYNVGQILDSPLRLATNLNESERNDRIFSTLRLVGMYPEHALIPIRETSSSQKQRIALA RALILSPEIIIADDTLSTLDFSVKTQLTNLMLNLQERLGISFIYVGQHLGIIKHIADKLMVMHEGEVIEYGLTKDVLLDP QSPITARLIESHFGKKLTPEAWGDSY >Mature_265_residues PLLDIKRLNKHFTDRIGLFRKHDFYAVKDVSFTLERGETIAIIGENGAGKSTLSKMIAGITKPTSGEMVFKGQALHFGDY RFRAKHIRMMFQDPNDAFDPNYNVGQILDSPLRLATNLNESERNDRIFSTLRLVGMYPEHALIPIRETSSSQKQRIALAR ALILSPEIIIADDTLSTLDFSVKTQLTNLMLNLQERLGISFIYVGQHLGIIKHIADKLMVMHEGEVIEYGLTKDVLLDPQ SPITARLIESHFGKKLTPEAWGDSY
Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]
COG id: COG4167
COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI9665248, Length=226, Percent_Identity=26.1061946902655, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI148612844, Length=218, Percent_Identity=26.605504587156, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI255708477, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI156105685, Length=224, Percent_Identity=26.7857142857143, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI27477115, Length=207, Percent_Identity=23.6714975845411, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI171184400, Length=224, Percent_Identity=25.8928571428571, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI153792144, Length=256, Percent_Identity=21.875, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI42490749, Length=215, Percent_Identity=25.1162790697674, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI6005701, Length=187, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI31657092, Length=203, Percent_Identity=25.1231527093596, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI27436953, Length=251, Percent_Identity=22.7091633466135, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787547, Length=260, Percent_Identity=53.4615384615385, Blast_Score=297, Evalue=4e-82, Organism=Escherichia coli, GI1789962, Length=254, Percent_Identity=38.9763779527559, Blast_Score=199, Evalue=1e-52, Organism=Escherichia coli, GI145693107, Length=255, Percent_Identity=35.2941176470588, Blast_Score=174, Evalue=5e-45, Organism=Escherichia coli, GI1787500, Length=260, Percent_Identity=35, Blast_Score=162, Evalue=3e-41, Organism=Escherichia coli, GI1788506, Length=254, Percent_Identity=33.8582677165354, Blast_Score=152, Evalue=2e-38, Organism=Escherichia coli, GI1787758, Length=251, Percent_Identity=31.8725099601594, Blast_Score=152, Evalue=3e-38, Organism=Escherichia coli, GI1789891, Length=235, Percent_Identity=31.9148936170213, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI1789963, Length=262, Percent_Identity=29.0076335877863, Blast_Score=127, Evalue=1e-30, Organism=Escherichia coli, GI48994883, Length=265, Percent_Identity=30.188679245283, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1787759, Length=264, Percent_Identity=28.030303030303, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1786398, Length=228, Percent_Identity=30.2631578947368, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI48994997, Length=262, Percent_Identity=29.7709923664122, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI87081791, Length=250, Percent_Identity=29.6, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789032, Length=224, Percent_Identity=29.9107142857143, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI87081709, Length=240, Percent_Identity=26.25, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1787548, Length=269, Percent_Identity=27.8810408921933, Blast_Score=96, Evalue=4e-21, Organism=Escherichia coli, GI1787712, Length=229, Percent_Identity=27.5109170305677, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=26.0089686098655, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1790467, Length=205, Percent_Identity=30.2439024390244, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1786703, Length=233, Percent_Identity=29.1845493562232, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1788225, Length=259, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1786253, Length=206, Percent_Identity=29.6116504854369, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789890, Length=238, Percent_Identity=25.2100840336134, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI87081834, Length=194, Percent_Identity=28.8659793814433, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787029, Length=247, Percent_Identity=26.7206477732794, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI87082267, Length=224, Percent_Identity=27.6785714285714, Blast_Score=86, Evalue=4e-18, Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=26.7543859649123, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1789672, Length=221, Percent_Identity=26.2443438914027, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI48995001, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=26.6968325791855, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1788644, Length=250, Percent_Identity=26.4, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789873, Length=204, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1790525, Length=216, Percent_Identity=28.7037037037037, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786981, Length=251, Percent_Identity=27.8884462151394, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1788450, Length=221, Percent_Identity=26.2443438914027, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787164, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI48994943, Length=226, Percent_Identity=28.3185840707965, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1786654, Length=234, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1786563, Length=199, Percent_Identity=27.1356783919598, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786698, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI1789991, Length=224, Percent_Identity=25.4464285714286, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1789586, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786872, Length=227, Percent_Identity=24.6696035242291, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI87081782, Length=231, Percent_Identity=28.1385281385281, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1788210, Length=212, Percent_Identity=28.7735849056604, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1790162, Length=255, Percent_Identity=22.7450980392157, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786345, Length=221, Percent_Identity=23.9819004524887, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787105, Length=231, Percent_Identity=25.5411255411255, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787792, Length=221, Percent_Identity=24.4343891402715, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=23.2456140350877, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI193209708, Length=218, Percent_Identity=28.8990825688073, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193208177, Length=245, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17558664, Length=225, Percent_Identity=27.1111111111111, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17511077, Length=216, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI212646699, Length=219, Percent_Identity=27.8538812785388, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193211017, Length=240, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71996809, Length=240, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193211015, Length=240, Percent_Identity=28.3333333333333, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193202349, Length=213, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI25146777, Length=217, Percent_Identity=28.110599078341, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI115535101, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323217, Length=243, Percent_Identity=28.8065843621399, Blast_Score=82, Evalue=7e-17, Organism=Saccharomyces cerevisiae, GI6324985, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6322980, Length=250, Percent_Identity=26.4, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322640, Length=232, Percent_Identity=27.1551724137931, Blast_Score=63, Evalue=6e-11, Organism=Drosophila melanogaster, GI28574744, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI85726357, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24641565, Length=213, Percent_Identity=27.2300469483568, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI23397593, Length=241, Percent_Identity=28.2157676348548, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI19920532, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24580930, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28573571, Length=211, Percent_Identity=24.6445497630332, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28573573, Length=211, Percent_Identity=24.6445497630332, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24666092, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574533, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI85724864, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24580555, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI85816269, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24580553, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 30071; Mature: 29940
Theoretical pI: Translated: 8.00; Mature: 8.00
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPLLDIKRLNKHFTDRIGLFRKHDFYAVKDVSFTLERGETIAIIGENGAGKSTLSKMIAG CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHH ITKPTSGEMVFKGQALHFGDYRFRAKHIRMMFQDPNDAFDPNYNVGQILDSPLRLATNLN CCCCCCCCEEEECCEEEECCHHHHEEHEEEEECCCCCCCCCCCCHHHHHCCHHHHHHCCC ESERNDRIFSTLRLVGMYPEHALIPIRETSSSQKQRIALARALILSPEIIIADDTLSTLD CCHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHH FSVKTQLTNLMLNLQERLGISFIYVGQHLGIIKHIADKLMVMHEGEVIEYGLTKDVLLDP HHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHEEECCCEEEECCCCCEEECC QSPITARLIESHFGKKLTPEAWGDSY CCCHHHHHHHHHCCCCCCCCCCCCCC >Mature Secondary Structure PLLDIKRLNKHFTDRIGLFRKHDFYAVKDVSFTLERGETIAIIGENGAGKSTLSKMIAG CCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHH ITKPTSGEMVFKGQALHFGDYRFRAKHIRMMFQDPNDAFDPNYNVGQILDSPLRLATNLN CCCCCCCCEEEECCEEEECCHHHHEEHEEEEECCCCCCCCCCCCHHHHHCCHHHHHHCCC ESERNDRIFSTLRLVGMYPEHALIPIRETSSSQKQRIALARALILSPEIIIADDTLSTLD CCHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHH FSVKTQLTNLMLNLQERLGISFIYVGQHLGIIKHIADKLMVMHEGEVIEYGLTKDVLLDP HHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHEEECCCEEEECCCCCEEECC QSPITARLIESHFGKKLTPEAWGDSY CCCHHHHHHHHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; peptides [Periplasm]; H2O [C]
Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]