Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 126208695

GI number: 126208695

Start: 1410195

End: 1410857

Strand: Reverse

Name: aphA [H]

Synonym: APL_1229

Alternate gene names: 126208695

Gene position: 1410857-1410195 (Counterclockwise)

Preceding gene: 126208699

Following gene: 126208694

Centisome position: 62.03

GC content: 40.72

Gene sequence:

>663_bases
ATGTATGTAACTCGTGAAAAATTAATAAAATTCGGCTTGCTCGCCGGAATTAGCGTGTTATGCGTAATGATTGTAAGTGT
CATTTTAAGCGGGATTAACCAGTTTAAATTGGGATCGCAGTTGGCAAGCGTAAACCAAGTGTCTAATCTTTCACATTTGT
TAGTCAGACAACAAGCAAACTTATTTTCTATGATGCTGGTTCGTAACGTGAAGAGCGAGGATTTGGTCGAGGCGTTGGAT
GCTTTTTCAAAAGAAGATTTTGTGATTGATGCCAATTTATATTCGCCTGCCGGCGTACTGATCGCACAAAGTCGTAATGC
GTTAGAATTTAAATCTCTGCTTCAACAAGATAAAGCGCAACCGGCTACTCAACAAATCGTCGAGCCGATTTTTTCTCAGC
AAGATCTCGTCGGTTTCTTACGCGTTACCTTTGATGCACAATACGGACAAACCACTAAAAGTAAAGTGGAGCGCATTTTT
CATCAATTATACGGGCAGTTAATTATTTTGGTATTAGCCGGCGGTTTACTTGTGAGCAGTTACCATTATTTCTTCCGCCG
TAGAATCAGTATCGTGCATACTCCGGTAAAATTACCGTTGATTTCGAGCAAAACGCAAACCCAGCGTTTTCATTCGAAAC
GTCGAGTGTTTAGGCACAAGTAA

Upstream 100 bases:

>100_bases
TAATGTTCTCTTTTTAATAGACTTTTTTCAATGGTGCATAGATAATGTGCTTTCGGAATTATCTATTATCAATTAGCTAT
TAGCTATTAGCAATTAATCT

Downstream 100 bases:

>100_bases
TCACTTGGAAGTGATTGTAATTTAGGCTGATGAGAGTATAATAAGCCCCGTTTTTTTATTTATATCCAAACCCTAATTTA
AAGAGGAATCAATGGCTAAA

Product: AphA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MYVTREKLIKFGLLAGISVLCVMIVSVILSGINQFKLGSQLASVNQVSNLSHLLVRQQANLFSMMLVRNVKSEDLVEALD
AFSKEDFVIDANLYSPAGVLIAQSRNALEFKSLLQQDKAQPATQQIVEPIFSQQDLVGFLRVTFDAQYGQTTKSKVERIF
HQLYGQLIILVLAGGLLVSSYHYFFRRRISIVHTPVKLPLISSKTQTQRFHSKRRVFRHK

Sequences:

>Translated_220_residues
MYVTREKLIKFGLLAGISVLCVMIVSVILSGINQFKLGSQLASVNQVSNLSHLLVRQQANLFSMMLVRNVKSEDLVEALD
AFSKEDFVIDANLYSPAGVLIAQSRNALEFKSLLQQDKAQPATQQIVEPIFSQQDLVGFLRVTFDAQYGQTTKSKVERIF
HQLYGQLIILVLAGGLLVSSYHYFFRRRISIVHTPVKLPLISSKTQTQRFHSKRRVFRHK
>Mature_220_residues
MYVTREKLIKFGLLAGISVLCVMIVSVILSGINQFKLGSQLASVNQVSNLSHLLVRQQANLFSMMLVRNVKSEDLVEALD
AFSKEDFVIDANLYSPAGVLIAQSRNALEFKSLLQQDKAQPATQQIVEPIFSQQDLVGFLRVTFDAQYGQTTKSKVERIF
HQLYGQLIILVLAGGLLVSSYHYFFRRRISIVHTPVKLPLISSKTQTQRFHSKRRVFRHK

Specific function: Effects the expression of the latent E.coli K12 hemolysin sheA under anaerobic conditions [H]

COG id: COG3726

COG function: function code R; Uncharacterized membrane protein affecting hemolysin expression

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the smp family [H]

Homologues:

Organism=Escherichia coli, GI1790847, Length=160, Percent_Identity=29.375, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019305 [H]

Pfam domain/function: PF10144 SMP_2 [H]

EC number: NA

Molecular weight: Translated: 24926; Mature: 24926

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVTREKLIKFGLLAGISVLCVMIVSVILSGINQFKLGSQLASVNQVSNLSHLLVRQQAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSMMLVRNVKSEDLVEALDAFSKEDFVIDANLYSPAGVLIAQSRNALEFKSLLQQDKAQ
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCC
PATQQIVEPIFSQQDLVGFLRVTFDAQYGQTTKSKVERIFHQLYGQLIILVLAGGLLVSS
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHYFFRRRISIVHTPVKLPLISSKTQTQRFHSKRRVFRHK
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYVTREKLIKFGLLAGISVLCVMIVSVILSGINQFKLGSQLASVNQVSNLSHLLVRQQAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFSMMLVRNVKSEDLVEALDAFSKEDFVIDANLYSPAGVLIAQSRNALEFKSLLQQDKAQ
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCC
PATQQIVEPIFSQQDLVGFLRVTFDAQYGQTTKSKVERIFHQLYGQLIILVLAGGLLVSS
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YHYFFRRRISIVHTPVKLPLISSKTQTQRFHSKRRVFRHK
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10699510; 11248100 [H]