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The map label for this gene is nagZ

Identifier: 126208583

GI number: 126208583

Start: 1287905

End: 1288942

Strand: Direct

Name: nagZ

Synonym: APL_1111

Alternate gene names: 126208583

Gene position: 1287905-1288942 (Clockwise)

Preceding gene: 126208582

Following gene: 126208584

Centisome position: 56.62

GC content: 43.83

Gene sequence:

>1038_bases
ATGTTATTGATTGATATAAAAGATAAAGAACTCAGCCAAGAAGAAGTTGAAATTCTTGAACATCCGCTCGTATCCGGCTT
AATTTTATTTAGCCGTAATTTTCACGATAAAGTCCAATTGGAAGCCTTAGTGAAATCGATTCGCCAACGGGTAAAAAAAC
CGTTATTGATTACCGTCGATCAAGAAGGCGGTCGAGTACAACGCTTCCGTGAAGGCTTTACTAAGTTGCCGGCAATGCAA
GCGTTTCATACCCTTGCAAAAAACCCGCAAGAATCGACCGCTTTAGCCCGACAAACCGGTTGGTTAATGGCGGCTGAAAT
GTTTGCCTTAGACATCGACTTGAGTTTTGCACCGGTCTTAGATTTAGGGCATCAGTGCAAAGCGATTGGCGATCGTTCGT
TCGGTGAAAATCCGGATGCGATGCTACCGATAGCCGAAGCCTTTATCGACGGTATGAGAGAAATGGGTATGGCGACCACC
GGTAAACATTTCCCCGGTCATGGACATGTATTAGCCGACTCTCATTTAGAAACGCCTTTTGATGATCGTCCGAAAGAGGC
GATTTTCAACCGTGATATTCTGCCGTTTAAACAACTTATTTCAAAAGGTAAACTGTCCGCGATTATGCCGGCTCACGTAA
TTTATACGCAATGTGACAGCCAACCGGCAAGCGGATCGGAATATTGGTTAAAACAAGTTTTACGTAACCAACTTAACTTT
AACGGCGTGATTTTTTCCGATGATTTAGGTATGAAAGGCGCCGGTTTTATGGGTAATTTTGTAGAACGTTCTGAGAAAGC
GATTCACGCCGGTTGTGATTTACTGCTGCTCTGTAATGAACCGGAGGGAGTTATCCAAGTATTAGACGGTTTAAAATATC
AACCGACTAAAACGCAAACCGAACGCCATATCTCCTTGATGAAACGTAAAACGGTACGTTGGAACGAGCTTGAAGCGAGT
CCTCGTTATCAGCAAGCGCAGCAACGTTTAACCGCATTACAAAACGACTGGCTTGAATATAAAGCGCAGCACTGCTAA

Upstream 100 bases:

>100_bases
ATGAAAATCAGGGGCTTTTTTAATGTAAAATAGTCCATCCTTATTTTATGACAAGCGGTCGATTTTGCGCCGAACTTTGC
AATTACACTCGCAACAAATT

Downstream 100 bases:

>100_bases
TCAGCCATTTATCTTTTTAGGGTATAAATTATATTTATGCCCTAACAAACCACTAAAAATACCTCGATTCTTTTAACAAA
ATGATATTAAACTGCCCGCA

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVDQEGGRVQRFREGFTKLPAMQ
AFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVLDLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATT
GKHFPGHGHVLADSHLETPFDDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNF
NGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQTERHISLMKRKTVRWNELEAS
PRYQQAQQRLTALQNDWLEYKAQHC

Sequences:

>Translated_345_residues
MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVDQEGGRVQRFREGFTKLPAMQ
AFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVLDLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATT
GKHFPGHGHVLADSHLETPFDDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNF
NGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQTERHISLMKRKTVRWNELEAS
PRYQQAQQRLTALQNDWLEYKAQHC
>Mature_345_residues
MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVDQEGGRVQRFREGFTKLPAMQ
AFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVLDLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATT
GKHFPGHGHVLADSHLETPFDDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNF
NGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQTERHISLMKRKTVRWNELEAS
PRYQQAQQRLTALQNDWLEYKAQHC

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=343, Percent_Identity=53.6443148688047, Blast_Score=375, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_ACTP2 (A3N1B7)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053808.1
- STRING:   A3N1B7
- GeneID:   4849180
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1111
- eggNOG:   COG1472
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- PhylomeDB:   A3N1B7
- ProtClustDB:   PRK05337
- BioCyc:   APLE416269:APL_1111-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 38994; Mature: 38994

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVD
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
QEGGRVQRFREGFTKLPAMQAFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVL
CCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
DLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATTGKHFPGHGHVLADSHLETPF
HCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCC
DDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNF
CCCCHHHHHCCCCHHHHHHHCCCCCHHHCHHHHEEEECCCCCCCCHHHHHHHHHHHHCCC
NGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQT
CCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCHHH
ERHISLMKRKTVRWNELEASPRYQQAQQRLTALQNDWLEYKAQHC
HHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVD
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
QEGGRVQRFREGFTKLPAMQAFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVL
CCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
DLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATTGKHFPGHGHVLADSHLETPF
HCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCC
DDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNF
CCCCHHHHHCCCCHHHHHHHCCCCCHHHCHHHHEEEECCCCCCCCHHHHHHHHHHHHCCC
NGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQT
CCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCCHHH
ERHISLMKRKTVRWNELEASPRYQQAQQRLTALQNDWLEYKAQHC
HHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA