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The map label for this gene is arcD [H]

Identifier: 126208555

GI number: 126208555

Start: 1252962

End: 1254368

Strand: Direct

Name: arcD [H]

Synonym: APL_1083

Alternate gene names: 126208555

Gene position: 1252962-1254368 (Clockwise)

Preceding gene: 126208554

Following gene: 126208556

Centisome position: 55.09

GC content: 43.43

Gene sequence:

>1407_bases
ATGTCAAAAGGTAAAATCGGGCTTTTCTCTTTAACCGCATTAGTACTTAGCTCCATGATCGGTTCCGGTATTTTCAGTTT
GCCTCAAAATATGGCGGAAGTCGCCGGTGCCGAGGCATTACTCAGCGGTTGGCTTATTACCGGTATCGGTATTATTTTCT
TAGGTCTATCTTTCTTTTTTCTTTCACGCATTAAACCGGAATTGGAAGGCGGCGTCTATACTTACGCTCGCGAAGGCTTC
GGCGATTTGGTCGGAGGATTATCCGCTTGGGGCTATTGGCTCTGTACCGCTATCGGCAGTGTCGGCTACCTAGTGGTTGC
CTTTGAAGGACTGGGCGCATTTGTTGATAGTGAAAATCATACGATTTTCGGACAAGGTAATACGTTAGCCGCTATTTTGG
GAGCTTCAGTTATTGTTTGGGCTGTACATTATCTGATTGCACGAGGTATTCGTGAAGCGGCGTATGTAAACCTGATCGCA
ACTATCGTAAAAACCTTACCGCTCTTTTTATTTATCGGCTTAGCCGTTTGGTTTTTCTCACCGGAGCAATTCGTACAGGA
TTTTAGCGGCGTTAAACTCGGCACAACCCAATTAGAACAAGTAAAAGGCACAATGTTGATTACCCTTTGGGTGTTTGTCG
GAGTGGAAGGGGCTTCCGTACTCTCCGCTCATGCCAAAAAGAAAAGTGATGTCGGCTTAGCCACCATTTTAGGTATTCTG
ATTACCCTGGTGCTATATGTGGCGATTACCGTGCTTTCACTCGGTATTTTGCCTCGTGAAGTGATTGCCGAAATGCCGAA
TCCCTCTATGGCAGGGTTAATGGAACAGATGATTGGTACAAGCGGTAAGATTATTATTACTTTCTGCTTGATTGTATCGG
TATTGGCTTCTTATATGAGTTGGACGATGTTTTCATCGGAAATCCCTTACCAAGCGGCGAAAACTAAAGTTTTCCCGAAA
GTACTAAATCGCACCAATATTAACGGCACACCGATTGCCGGTTTATGGCTAACCAATATCACGATTCAAATTAGTCTGTT
GCTCGTATTATTTACCGGCAAAGGTTACAGTATGCTGATTCAGCTTTCGACTACAATGATTCTGGTACCTTATTTCTTAG
TCGGCGCTTATTTATTCAAAGTCGCAATGAAACAAAACGAAGCGTGGTATATCAAACTGACCGGTGCGATGGCGTCCGTT
TACGGTTTATGGATTGTTTATGCGGCGGGACTAGATTATTTGTTGCTCTCCGTTGTACTCTACGTACCGGGACTTGCTCT
GTTTTTCTATTCTCGTAAACAAAACGGCGAAAACATCCATTTAACTCGCTTTGAAAAAAGTTTATTAGCGGTGATTAGTG
TGCTTTTTATCGGAGCGGTTTATACTCTGTTCACTAATTCATTCTAG

Upstream 100 bases:

>100_bases
GCTAAAAAGATAATATCCTCTCGTGCTTCGGCATTAGAGGATTTTTTATTTTTATGCTAAATTATGCAGTTTGTATGAAT
AACAATTATAAGGGCATTGC

Downstream 100 bases:

>100_bases
GGCTAAAAATGAAAACAACATTGTTCAAGCAAGCGGTCGCTTTTCTACGGATTTTTGCCAATAAAGTGCTTGAAGTTTCT
CACCAATTACAGCATTTTTT

Product: putative arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSKGKIGLFSLTALVLSSMIGSGIFSLPQNMAEVAGAEALLSGWLITGIGIIFLGLSFFFLSRIKPELEGGVYTYAREGF
GDLVGGLSAWGYWLCTAIGSVGYLVVAFEGLGAFVDSENHTIFGQGNTLAAILGASVIVWAVHYLIARGIREAAYVNLIA
TIVKTLPLFLFIGLAVWFFSPEQFVQDFSGVKLGTTQLEQVKGTMLITLWVFVGVEGASVLSAHAKKKSDVGLATILGIL
ITLVLYVAITVLSLGILPREVIAEMPNPSMAGLMEQMIGTSGKIIITFCLIVSVLASYMSWTMFSSEIPYQAAKTKVFPK
VLNRTNINGTPIAGLWLTNITIQISLLLVLFTGKGYSMLIQLSTTMILVPYFLVGAYLFKVAMKQNEAWYIKLTGAMASV
YGLWIVYAAGLDYLLLSVVLYVPGLALFFYSRKQNGENIHLTRFEKSLLAVISVLFIGAVYTLFTNSF

Sequences:

>Translated_468_residues
MSKGKIGLFSLTALVLSSMIGSGIFSLPQNMAEVAGAEALLSGWLITGIGIIFLGLSFFFLSRIKPELEGGVYTYAREGF
GDLVGGLSAWGYWLCTAIGSVGYLVVAFEGLGAFVDSENHTIFGQGNTLAAILGASVIVWAVHYLIARGIREAAYVNLIA
TIVKTLPLFLFIGLAVWFFSPEQFVQDFSGVKLGTTQLEQVKGTMLITLWVFVGVEGASVLSAHAKKKSDVGLATILGIL
ITLVLYVAITVLSLGILPREVIAEMPNPSMAGLMEQMIGTSGKIIITFCLIVSVLASYMSWTMFSSEIPYQAAKTKVFPK
VLNRTNINGTPIAGLWLTNITIQISLLLVLFTGKGYSMLIQLSTTMILVPYFLVGAYLFKVAMKQNEAWYIKLTGAMASV
YGLWIVYAAGLDYLLLSVVLYVPGLALFFYSRKQNGENIHLTRFEKSLLAVISVLFIGAVYTLFTNSF
>Mature_467_residues
SKGKIGLFSLTALVLSSMIGSGIFSLPQNMAEVAGAEALLSGWLITGIGIIFLGLSFFFLSRIKPELEGGVYTYAREGFG
DLVGGLSAWGYWLCTAIGSVGYLVVAFEGLGAFVDSENHTIFGQGNTLAAILGASVIVWAVHYLIARGIREAAYVNLIAT
IVKTLPLFLFIGLAVWFFSPEQFVQDFSGVKLGTTQLEQVKGTMLITLWVFVGVEGASVLSAHAKKKSDVGLATILGILI
TLVLYVAITVLSLGILPREVIAEMPNPSMAGLMEQMIGTSGKIIITFCLIVSVLASYMSWTMFSSEIPYQAAKTKVFPKV
LNRTNINGTPIAGLWLTNITIQISLLLVLFTGKGYSMLIQLSTTMILVPYFLVGAYLFKVAMKQNEAWYIKLTGAMASVY
GLWIVYAAGLDYLLLSVVLYVPGLALFFYSRKQNGENIHLTRFEKSLLAVISVLFIGAVYTLFTNSF

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=461, Percent_Identity=52.060737527115, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI2367353, Length=424, Percent_Identity=29.7169811320755, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790575, Length=454, Percent_Identity=26.6519823788546, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786908, Length=460, Percent_Identity=25.6521739130435, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002293
- InterPro:   IPR004754 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50715; Mature: 50584

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKGKIGLFSLTALVLSSMIGSGIFSLPQNMAEVAGAEALLSGWLITGIGIIFLGLSFFF
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRIKPELEGGVYTYAREGFGDLVGGLSAWGYWLCTAIGSVGYLVVAFEGLGAFVDSENH
HHHCCHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHCCCCCC
TIFGQGNTLAAILGASVIVWAVHYLIARGIREAAYVNLIATIVKTLPLFLFIGLAVWFFS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEQFVQDFSGVKLGTTQLEQVKGTMLITLWVFVGVEGASVLSAHAKKKSDVGLATILGIL
HHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
ITLVLYVAITVLSLGILPREVIAEMPNPSMAGLMEQMIGTSGKIIITFCLIVSVLASYMS
HHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WTMFSSEIPYQAAKTKVFPKVLNRTNINGTPIAGLWLTNITIQISLLLVLFTGKGYSMLI
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
QLSTTMILVPYFLVGAYLFKVAMKQNEAWYIKLTGAMASVYGLWIVYAAGLDYLLLSVVL
EHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVPGLALFFYSRKQNGENIHLTRFEKSLLAVISVLFIGAVYTLFTNSF
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]