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The map label for this gene is htpG

Identifier: 126208461

GI number: 126208461

Start: 1139729

End: 1141606

Strand: Reverse

Name: htpG

Synonym: APL_0987

Alternate gene names: 126208461

Gene position: 1141606-1139729 (Counterclockwise)

Preceding gene: 126208472

Following gene: 126208456

Centisome position: 50.19

GC content: 39.67

Gene sequence:

>1878_bases
ATGAGTACTAATCAAGAAACAAGAGGCTTTCAATCGGAAGTTAAGCAACTGCTTCAATTAATGATCCATTCACTTTATTC
AAATAAAGAAATTTTCTTACGTGAATTAATCTCTAATGCGTCTGATGCGGCGGATAAACTACGCTTTAAAGCACTTTCAA
ATCCTGCGTTATATGAAGGAGACGGCGAATTACGTGTACGAGTGAGCTTTGATGAAACTTTAGGTACATTAACGATCAGC
GATAACGGTATCGGAATGAATCGTGAGCAAGTGATCGATCACTTAGGTACGATTGCTAAATCAGGTACCAAAGAATTTTT
AAATTCGTTAGGTACGGATCAAGCGAAAGACAGCCAATTAATCGGTCAATTCGGGGTTGGTTTTTATTCGGCATTTATTG
TAGCGGACAAAGTGACAGTGAAAACCCGTGCGGCGGGCGAAACACAAGCCGTACTTTGGGAATCTGCCGGTGAAGGCGAT
TACACCGTAGCGGATATTGAGAAAGCGACACGCGGTACGGATGTTATTTTACATTTGCGTGAAGAAGAAAAAGAATTTTT
AAGCGAATGGCGTTTACGTGAAATTATCGGTAAATATTCGGATCATATCGGTTTACCAGTTGAAATCCAAACTACCGAAT
ACAATGAAGAAGGCAAAGCAAGCGGTCAAAAATGGGAAAAAATTAACAAAGCGCAAGCACTTTGGACTCGTTCAAAAAAC
GAAATTTCAGACGAAGAATACCAAGAGTTTTATAAACATTTAAGCCACGATTATAATGACTCGCTCATCTGGGCGCATAA
TAAAGTAGAAGGTAAACAAGAATATACCAGCTTACTTTATGTGCCGGCAAAAGCACCTTGGGATTTGTTCAATCGTGATC
AAAAACACGGCTTAAAACTTTATGTACAGCGTGTATTTATTATGGACGATGCTGAAGTGTTTATGCCGAATTACCTACGT
TTTATGCGAGGTTTATTAGACACGAATGACCTGCCGCTCAACGTTTCACGTGAGATTTTACAAGAAAATAAAATCACCGC
TTCACTACGTGCGGCATTAACTAAACGTGCATTGCAATTATTGGAAAAATTAGCGAAGGACGATCAAGCTAAATACCAAA
CTTTCTGGAATGAATTCGGTTTAGTGTTAAAAGAAGGTGTAGGCGAAGATTTTGCCAATAAACAACAAATTGCGTCATTA
TTCCGCTTTGCTTCAACCCAAACTGATTCTAGCGAACAAACGGTAAGCTTGGCGGATTATGTTGGCAGAATGAAAGAAGG
GCAGAAAGCAATTTATTTCTTAACTGCTGATAGCTATGTAGCAGCAAAAAATAGTCCGCACCTTGAACTGTTCAATAAGA
AAGGCATTGAAGTGCTGTTATTATCTGATCGTATTGACGAATGGGTAGTGGGGCACTTAACCGAATTTGACGGTAAACCG
TTGCAAAGTATCACTAAATCGGATTTGGATTTAGGCGATCTTGCCGATAAGGAACAAGAAGAGAGCCAAAAAGCGCAACA
AGCGGAATTCGGATCTTTCCTTGAGCGTGCGCAAAGCTATTTTGGTGAGCGTGTGAAAAAAGTGGTATTAACGCATCGCT
TAACCGACACGCCGGCAGTGGTTTCTACCGACAATGATGAAATGACGACACAGATGGCAAAACTGTTTGCCGCTATGGGA
CAAAAAGCACCGGAAGTGAAATATACGTTTGAGCTAAATCCGGATCATCGTATGGTTAAGAAAATTGCAGATCTTACCGA
TGAAACGAAATTCAATGATTGGATTGAATTATTATTTGAACAAGCATTACTTGCAGAACGCGGTTCATTAGAAAATCCGG
CAGCATTTATTAAACGTATGAATAAATTGCTTGGTTAA

Upstream 100 bases:

>100_bases
TTTATTTTGTGACTTGAAAAGTAAAACGCTTTTCCCCATTTACTAATACATTTGCAAGCGGTGAAATTCCGCTTATTTTT
TGTAAATTAAAGAGGATAAA

Downstream 100 bases:

>100_bases
TCTAAATATGTAACAAAAAAAGCTATCGAAATGATCTGACCCCAAAAAGTTAGACTGTTTAATTTAAGGACTGAGTTCTG
TATTGTACAAGGCTCAGTCC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGELRVRVSFDETLGTLTIS
DNGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGD
YTVADIEKATRGTDVILHLREEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKN
EISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDLFNRDQKHGLKLYVQRVFIMDDAEVFMPNYLR
FMRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQLLEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASL
FRFASTQTDSSEQTVSLADYVGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKP
LQSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAVVSTDNDEMTTQMAKLFAAMG
QKAPEVKYTFELNPDHRMVKKIADLTDETKFNDWIELLFEQALLAERGSLENPAAFIKRMNKLLG

Sequences:

>Translated_625_residues
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGELRVRVSFDETLGTLTIS
DNGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGD
YTVADIEKATRGTDVILHLREEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKN
EISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDLFNRDQKHGLKLYVQRVFIMDDAEVFMPNYLR
FMRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQLLEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASL
FRFASTQTDSSEQTVSLADYVGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKP
LQSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAVVSTDNDEMTTQMAKLFAAMG
QKAPEVKYTFELNPDHRMVKKIADLTDETKFNDWIELLFEQALLAERGSLENPAAFIKRMNKLLG
>Mature_624_residues
STNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGELRVRVSFDETLGTLTISD
NGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGDY
TVADIEKATRGTDVILHLREEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKNE
ISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDLFNRDQKHGLKLYVQRVFIMDDAEVFMPNYLRF
MRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQLLEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASLF
RFASTQTDSSEQTVSLADYVGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKPL
QSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAVVSTDNDEMTTQMAKLFAAMGQ
KAPEVKYTFELNPDHRMVKKIADLTDETKFNDWIELLFEQALLAERGSLENPAAFIKRMNKLLG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=678, Percent_Identity=35.8407079646018, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI155722983, Length=629, Percent_Identity=34.181240063593, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI154146191, Length=413, Percent_Identity=38.2566585956416, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI153792590, Length=413, Percent_Identity=38.0145278450363, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI20149594, Length=411, Percent_Identity=37.4695863746959, Blast_Score=270, Evalue=3e-72,
Organism=Escherichia coli, GI1786679, Length=622, Percent_Identity=74.1157556270096, Blast_Score=959, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=675, Percent_Identity=38.6666666666667, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=35.1111111111111, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI115535205, Length=656, Percent_Identity=33.0792682926829, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=434, Percent_Identity=36.1751152073733, Blast_Score=257, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=37.9259259259259, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6325016, Length=679, Percent_Identity=37.4079528718704, Blast_Score=443, Evalue=1e-125,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=35.9882005899705, Blast_Score=377, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586016, Length=648, Percent_Identity=33.641975308642, Blast_Score=345, Evalue=7e-95,
Organism=Drosophila melanogaster, GI17647529, Length=211, Percent_Identity=47.39336492891, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_ACTP2 (A3N0Z5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053686.1
- ProteinModelPortal:   A3N0Z5
- SMR:   A3N0Z5
- STRING:   A3N0Z5
- GeneID:   4848844
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0987
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- PhylomeDB:   A3N0Z5
- ProtClustDB:   PRK05218
- BioCyc:   APLE416269:APL_0987-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71042; Mature: 70911

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGELRVRVSFDETLGTLTISDNGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQL
CCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGDYTVADIEKATRGTDVILHLR
HHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEHHHHHHHCCCCEEEEEEH
EEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKN
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDLFNRDQKHGLKL
CCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCEEEEECCCCCHHHHCCCHHCCHHH
YVQRVFIMDDAEVFMPNYLRFMRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQL
HHHHHHEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASLFRFASTQTDSSEQTVSLADY
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
VGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKP
HHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCH
LQSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAV
HHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VSTDNDEMTTQMAKLFAAMGQKAPEVKYTFELNPDHRMVKKIADLTDETKFNDWIELLFE
EECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
QALLAERGSLENPAAFIKRMNKLLG
HHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
STNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEG
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEC
DGELRVRVSFDETLGTLTISDNGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQL
CCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGDYTVADIEKATRGTDVILHLR
HHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEHHHHHHHCCCCEEEEEEH
EEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKN
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCC
EISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDLFNRDQKHGLKL
CCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCEEEEECCCCCHHHHCCCHHCCHHH
YVQRVFIMDDAEVFMPNYLRFMRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQL
HHHHHHEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASLFRFASTQTDSSEQTVSLADY
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
VGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKP
HHHHHCCCEEEEEEEECCEEECCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCH
LQSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAV
HHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VSTDNDEMTTQMAKLFAAMGQKAPEVKYTFELNPDHRMVKKIADLTDETKFNDWIELLFE
EECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHH
QALLAERGSLENPAAFIKRMNKLLG
HHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA