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The map label for this gene is sstT

Identifier: 126208245

GI number: 126208245

Start: 877724

End: 878938

Strand: Reverse

Name: sstT

Synonym: APL_0767

Alternate gene names: 126208245

Gene position: 878938-877724 (Counterclockwise)

Preceding gene: 126208249

Following gene: 126208244

Centisome position: 38.64

GC content: 42.72

Gene sequence:

>1215_bases
ATGAGTAATCCATCTTTATCTTCAAAACTTCTCGGGGGCAATTTAGTTTTACGCATTGCTATCGGTTTGGTATTAGGTGC
TTGCCTTGCCTTAGTCAATCCGGATTGGGCAAAGAATGTCGGCGTATTAGGTCAATTCTTTGTGAAATCTTTACGTGCAA
TTGCACCGATTCTTGTATTCGTTTTAGTTTTATCGGCGATTGCAAATAAAGAAGTCGGTTCGGACAGTAAATTAAAACCG
ATTTTAGTAATGTACGTATTAGGGACGTTTGTTGCGGCATTAACCGCAGTAGTTTTAAGTTTTATGTTCCCGACTACGTT
AGAACTTGTTTCAAATCCGGATAACTTGAACCCTCCGCAAGGTATCGGTGAAATTATCAAAACCGTGGTGTTCAACCTTG
TCGATAACCCGTTACAAGCATTAGCAAACGCAAACTTTATCGGTATTTTAGCTTGGGCGATCGGTTTAGGTATCGCTTTA
CGTCATGCGGCACCAAGTACGAAAACATTCTTAAATGATTTTGCCGAAGCGGTTTCATTTGTGGTTAAAGTGGTAATCGC
TTTTGCTCCGATCGGTGTATTCGGTTTAGTTGCCGAAACGATTGCGACAAACGGCGCGGATGCGTTTGTAGGATATGCAC
GTTTATTAGGCGTATTACTTGGCGCGATGGTAATTGTTGCATTTGTATTAAATCCGTTAATCGTATTTTGGAAAATCCGT
CGCAATCCGTATCCTTTAACATTAACTTGTTTACGTGAAAGCGGTGTAACGGCATTCTTTACTCGCAGTTCTGCGGCAAA
TATTCCGGTAAATATGAACCTTGCTAAACGTTTAGGCGTACGTGATGAAATCGCATCGGTTGCCATTCCGCTTGGTGCGA
CTATCAATATGGCGGGTGCGGCGATTACCGTAACGGTATTAACTTTAGCGGCGGCTTATACGCAAGGTATTCAACCTGAT
TTCGCTACCGCATTATTATTAAGTATCGTTGCTTCTGTTTGTGCTTGCGGTGCATCGGGTGTTGCGGGCGGTTCGTTATT
ACTTATTCCGTTAGCGTGTAGTTTATTTAATATTCCGAACGATATTGCGGCGCAAGTTATCGGTGTAGGCTTTATTATCG
GGGTAATCCAAGACTCTGCGGAAACCGCATTGAACTCATCAACGGACGTGTTATTTACTGCGGCGGTAAGCCAAGCGGAA
GATCAAAAAGCATAG

Upstream 100 bases:

>100_bases
ATTCCCAAAAAGGTGATTTTCCGCTAATCTGAAAACTTCATATTTTGGCGGATATACGGTTTGCCGTATATCCTTTTTTA
GTCTTACAAAGTGAAACATT

Downstream 100 bases:

>100_bases
TTAAAAGCGGTTTTTGCGATCAGGATCGAAGAACTGATTTCCGTTTGATACAAGCGGTCGGATTTTTAGCATACTTTACC
TATTATTTGGGTATTGGCTA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSNPSLSSKLLGGNLVLRIAIGLVLGACLALVNPDWAKNVGVLGQFFVKSLRAIAPILVFVLVLSAIANKEVGSDSKLKP
ILVMYVLGTFVAALTAVVLSFMFPTTLELVSNPDNLNPPQGIGEIIKTVVFNLVDNPLQALANANFIGILAWAIGLGIAL
RHAAPSTKTFLNDFAEAVSFVVKVVIAFAPIGVFGLVAETIATNGADAFVGYARLLGVLLGAMVIVAFVLNPLIVFWKIR
RNPYPLTLTCLRESGVTAFFTRSSAANIPVNMNLAKRLGVRDEIASVAIPLGATINMAGAAITVTVLTLAAAYTQGIQPD
FATALLLSIVASVCACGASGVAGGSLLLIPLACSLFNIPNDIAAQVIGVGFIIGVIQDSAETALNSSTDVLFTAAVSQAE
DQKA

Sequences:

>Translated_404_residues
MSNPSLSSKLLGGNLVLRIAIGLVLGACLALVNPDWAKNVGVLGQFFVKSLRAIAPILVFVLVLSAIANKEVGSDSKLKP
ILVMYVLGTFVAALTAVVLSFMFPTTLELVSNPDNLNPPQGIGEIIKTVVFNLVDNPLQALANANFIGILAWAIGLGIAL
RHAAPSTKTFLNDFAEAVSFVVKVVIAFAPIGVFGLVAETIATNGADAFVGYARLLGVLLGAMVIVAFVLNPLIVFWKIR
RNPYPLTLTCLRESGVTAFFTRSSAANIPVNMNLAKRLGVRDEIASVAIPLGATINMAGAAITVTVLTLAAAYTQGIQPD
FATALLLSIVASVCACGASGVAGGSLLLIPLACSLFNIPNDIAAQVIGVGFIIGVIQDSAETALNSSTDVLFTAAVSQAE
DQKA
>Mature_403_residues
SNPSLSSKLLGGNLVLRIAIGLVLGACLALVNPDWAKNVGVLGQFFVKSLRAIAPILVFVLVLSAIANKEVGSDSKLKPI
LVMYVLGTFVAALTAVVLSFMFPTTLELVSNPDNLNPPQGIGEIIKTVVFNLVDNPLQALANANFIGILAWAIGLGIALR
HAAPSTKTFLNDFAEAVSFVVKVVIAFAPIGVFGLVAETIATNGADAFVGYARLLGVLLGAMVIVAFVLNPLIVFWKIRR
NPYPLTLTCLRESGVTAFFTRSSAANIPVNMNLAKRLGVRDEIASVAIPLGATINMAGAAITVTVLTLAAAYTQGIQPDF
ATALLLSIVASVCACGASGVAGGSLLLIPLACSLFNIPNDIAAQVIGVGFIIGVIQDSAETALNSSTDVLFTAAVSQAED
QKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468566, Length=261, Percent_Identity=31.8007662835249, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI223468564, Length=255, Percent_Identity=32.156862745098, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI5032093, Length=261, Percent_Identity=31.8007662835249, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4827012, Length=277, Percent_Identity=25.2707581227437, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI169790839, Length=258, Percent_Identity=24.4186046511628, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21314632, Length=268, Percent_Identity=28.7313432835821, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI66773030, Length=264, Percent_Identity=23.4848484848485, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI40254478, Length=254, Percent_Identity=25.5905511811024, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789473, Length=401, Percent_Identity=62.3441396508728, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1789947, Length=356, Percent_Identity=24.1573033707865, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790514, Length=274, Percent_Identity=25.1824817518248, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17537407, Length=449, Percent_Identity=23.3853006681514, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983106, Length=255, Percent_Identity=25.0980392156863, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71983099, Length=255, Percent_Identity=25.0980392156863, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71996953, Length=451, Percent_Identity=23.5033259423503, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=435, Percent_Identity=23.9080459770115, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583025, Length=444, Percent_Identity=23.8738738738739, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17137668, Length=444, Percent_Identity=23.8738738738739, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583023, Length=444, Percent_Identity=23.8738738738739, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_ACTP2 (A3N0C9)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053470.1
- ProteinModelPortal:   A3N0C9
- SMR:   A3N0C9
- STRING:   A3N0C9
- GeneID:   4849414
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0767
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   MASIANK
- PhylomeDB:   A3N0C9
- ProtClustDB:   PRK13628
- BioCyc:   APLE416269:APL_0767-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 41871; Mature: 41740

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b394c30)-; HASH(0x1c607dd0)-; HASH(0x1cf56db0)-; HASH(0x1bc8739c)-; HASH(0x1b34faec)-; HASH(0x1d016044)-; HASH(0x1d461f50)-; HASH(0x1ce60b38)-; HASH(0x1d211fb4)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCH
>Mature Secondary Structure 
SNPSLSSKLLGGNLVLRIAIGLVLGACLALVNPDWAKNVGVLGQFFVKSLRAIAPILVF
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLVLSAIANKEVGSDSKLKPILVMYVLGTFVAALTAVVLSFMFPTTLELVSNPDNLNPPQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
GIGEIIKTVVFNLVDNPLQALANANFIGILAWAIGLGIALRHAAPSTKTFLNDFAEAVSF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VVKVVIAFAPIGVFGLVAETIATNGADAFVGYARLLGVLLGAMVIVAFVLNPLIVFWKIR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RNPYPLTLTCLRESGVTAFFTRSSAANIPVNMNLAKRLGVRDEIASVAIPLGATINMAGA
CCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCEECCHH
AITVTVLTLAAAYTQGIQPDFATALLLSIVASVCACGASGVAGGSLLLIPLACSLFNIPN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCH
DIAAQVIGVGFIIGVIQDSAETALNSSTDVLFTAAVSQAEDQKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA