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The map label for this gene is aroC

Identifier: 126208226

GI number: 126208226

Start: 853537

End: 854619

Strand: Reverse

Name: aroC

Synonym: APL_0748

Alternate gene names: 126208226

Gene position: 854619-853537 (Counterclockwise)

Preceding gene: 126208227

Following gene: 126208225

Centisome position: 37.57

GC content: 47.28

Gene sequence:

>1083_bases
ATGGCAGGCAACAGCATTGGACAATTATTTAAAGTAACCACATTCGGCGAATCGCACGGTATTGCGTTAGGTTGTATCGT
GGACGGTGTTCCGCCGAATATGGCGCTCTCGGAAGCGGATATTCAGCCTGATTTAGACCGTCGTAAACCGGGAACTTCAC
GTTATACCACGCCTCGTAGAGAAGATGACGAAGTACAAATTCTTTCCGGCGTATTTGAAGGTAAAACAACCGGCACCAGT
ATCGGATTAATCATTAAAAATGCTGATCAGCGTTCGAAAGATTACGGCGATATTGCGGATAAATTCCGTCCGGGGCATGC
GGATTATACCTATCAGCAAAAATACGGTATTCGTGATTATCGTGGAGGTGGGCGTTCTTCCGCTCGTGAAACGGCAATGC
GAGTTGCTGCCGGTGCGATTGCCAAAAAATATTTACGCGAGCAATTCGGTATTGAAGTACGTGGTTATTTATCACAAATC
GGTAATGTGAAAATTAATCCTGAAACGGTAGCGGACATCAGCAAAATCGATTGGCAACAAGTGGCGAGCAATCCGTTTTT
TTGCCCGGATCCGGTGGCGGTAGAAGGCTTTGGCGAGTTGATTCGTGAATTGAAAAAAGACGGTGATTCTATCGGGGCGA
AATTAACGGTAGTTGCCGAGAACGTACCGGTCGGACTTGGCGAGCCGGTGTTTGACCGTTTAGATGCGGATTTGGCGCAT
GCGTTGATGTCAATCAATGCGGTAAAGGCGGTCGAAATCGGTGACGGTTTTGACGTGGTTGAGCAGCGTGGTAGCGAGCA
TCGCGATGAAATGACGCCGCAAGGTTTTGTGTCAAATCACGCCGGCGGAATTTTAGGCGGGATCAGTTCCGGTCAGCCGA
TCATTGCGCATATCGCATTGAAACCGACTTCCAGTATTATGGTACCGGGACGTTCGGTGAATTTAAATAACGAACAAGTC
GAATTGATCACCAAAGGACGCCACGATCCTTGTGTTGGTATCCGTGCAGTACCGATAGCAGAAGCGATGACAGCAATTAT
TTTATTGGACCATTTACTTAGATTTAAAGCACAATGCCGTTAA

Upstream 100 bases:

>100_bases
TTTCAAACAGTTGGATGTCAATATGCATACGGCAGAGGTTCGGCAAGCGGTCACATTGAGTGAAAATTTAGCAAAATAAT
CAAAATAAGAAGGAAGCATT

Downstream 100 bases:

>100_bases
GTCGGGTATAATCCGAACAAGCGGTCTTTTTTGCTAAAAATGCTGCAAAAAAGACCGCTTGTTTTTTTATTCATTGACTT
TTCTAGGTGTAATAATGAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MAGNSIGQLFKVTTFGESHGIALGCIVDGVPPNMALSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGLIIKNADQRSKDYGDIADKFRPGHADYTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREQFGIEVRGYLSQI
GNVKINPETVADISKIDWQQVASNPFFCPDPVAVEGFGELIRELKKDGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAH
ALMSINAVKAVEIGDGFDVVEQRGSEHRDEMTPQGFVSNHAGGILGGISSGQPIIAHIALKPTSSIMVPGRSVNLNNEQV
ELITKGRHDPCVGIRAVPIAEAMTAIILLDHLLRFKAQCR

Sequences:

>Translated_360_residues
MAGNSIGQLFKVTTFGESHGIALGCIVDGVPPNMALSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTS
IGLIIKNADQRSKDYGDIADKFRPGHADYTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREQFGIEVRGYLSQI
GNVKINPETVADISKIDWQQVASNPFFCPDPVAVEGFGELIRELKKDGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAH
ALMSINAVKAVEIGDGFDVVEQRGSEHRDEMTPQGFVSNHAGGILGGISSGQPIIAHIALKPTSSIMVPGRSVNLNNEQV
ELITKGRHDPCVGIRAVPIAEAMTAIILLDHLLRFKAQCR
>Mature_359_residues
AGNSIGQLFKVTTFGESHGIALGCIVDGVPPNMALSEADIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTSI
GLIIKNADQRSKDYGDIADKFRPGHADYTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREQFGIEVRGYLSQIG
NVKINPETVADISKIDWQQVASNPFFCPDPVAVEGFGELIRELKKDGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAHA
LMSINAVKAVEIGDGFDVVEQRGSEHRDEMTPQGFVSNHAGGILGGISSGQPIIAHIALKPTSSIMVPGRSVNLNNEQVE
LITKGRHDPCVGIRAVPIAEAMTAIILLDHLLRFKAQCR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=358, Percent_Identity=75.4189944134078, Blast_Score=535, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6321290, Length=371, Percent_Identity=48.2479784366577, Blast_Score=324, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_ACTP2 (A3N0B0)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053451.1
- ProteinModelPortal:   A3N0B0
- SMR:   A3N0B0
- STRING:   A3N0B0
- GeneID:   4848838
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0748
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   A3N0B0
- ProtClustDB:   PRK05382
- BioCyc:   APLE416269:APL_0748-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38894; Mature: 38762

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQLFKVTTFGESHGIALGCIVDGVPPNMALSEADIQPDLDRRKPGTSRYTTPRR
CCCCCHHHEEEEEECCCCCCEEEEEEECCCCCCCEECCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGLIIKNADQRSKDYGDIADKFRPGHADYTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREQFGIEVRGYLSQIGNVKINPETVADISKIDWQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECHHHHHHHHHHHHHH
VASNPFFCPDPVAVEGFGELIRELKKDGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAH
HHCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
ALMSINAVKAVEIGDGFDVVEQRGSEHRDEMTPQGFVSNHAGGILGGISSGQPIIAHIAL
HHHHHCCEEEEEECCCHHHHHHCCCHHHHHCCCCCHHHCCCCCEEECCCCCCCEEEEEEE
KPTSSIMVPGRSVNLNNEQVELITKGRHDPCVGIRAVPIAEAMTAIILLDHLLRFKAQCR
CCCCCEEECCCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNSIGQLFKVTTFGESHGIALGCIVDGVPPNMALSEADIQPDLDRRKPGTSRYTTPRR
CCCCHHHEEEEEECCCCCCEEEEEEECCCCCCCEECCCCCCCCHHHCCCCCCCCCCCCC
EDDEVQILSGVFEGKTTGTSIGLIIKNADQRSKDYGDIADKFRPGHADYTYQQKYGIRDY
CCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLREQFGIEVRGYLSQIGNVKINPETVADISKIDWQQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECHHHHHHHHHHHHHH
VASNPFFCPDPVAVEGFGELIRELKKDGDSIGAKLTVVAENVPVGLGEPVFDRLDADLAH
HHCCCCCCCCCCCHHHHHHHHHHHHHCCHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
ALMSINAVKAVEIGDGFDVVEQRGSEHRDEMTPQGFVSNHAGGILGGISSGQPIIAHIAL
HHHHHCCEEEEEECCCHHHHHHCCCHHHHHCCCCCHHHCCCCCEEECCCCCCCEEEEEEE
KPTSSIMVPGRSVNLNNEQVELITKGRHDPCVGIRAVPIAEAMTAIILLDHLLRFKAQCR
CCCCCEEECCCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA