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The map label for this gene is ilvH [H]

Identifier: 126208208

GI number: 126208208

Start: 836810

End: 837301

Strand: Direct

Name: ilvH [H]

Synonym: APL_0728

Alternate gene names: 126208208

Gene position: 836810-837301 (Clockwise)

Preceding gene: 126208207

Following gene: 126208210

Centisome position: 36.79

GC content: 41.06

Gene sequence:

>492_bases
ATGCGTAGAACATTATCAGTATTACTCGAAAACGAATCGGGTGCATTATCCCGTGTGGTAGGCCTTTTTTCTCAACGTGG
GTTTAATATCGAAAGTTTAACCGTTGCGCCGACTGACGATGAAACGCTTTCACGTATGACAATCGTTGCCCAAGGCGATG
AAAACGTCCTTGAGCAAATCGAAAAGCAATTGCATAAATTGATTGACGTGTTCAAAGTTTCAAACTTAAGCCCTACCGAG
CATATTGAACGTGAAGTCTTATTATTAAAAGTGCGTGCGACAGGTTCATCTCGTGACGAATTAAAACGAATGGTCGATAT
TTTCCGCGGGCAAATTGTTGATATTACGCCGAAACTTTATACCGTGCAATTAGCCGGCACTAGTGAAAAACTGAATGCGT
TTATTGAAGCGGTAAAACAAGAAACGACAATAGTCGAAATCGTACGATCCGGCGTTATTAGTCTTTCTCGCGGCGATAAA
AACTGTTTATAA

Upstream 100 bases:

>100_bases
TTTGTCGATGTAAAAGTAGATGAAACCGAACACGTTTACCCGATGCAAATTCGCGGCGGTGCGATGAATGAGATGATTTT
AAGCAAAACGGAGAGAACAG

Downstream 100 bases:

>100_bases
CATTTTACAGGGCGAACGCATTGTTCGCCTTTTGTTTTAACTGAAAGACAAGCGGTTAAATTCGCTCAATTTTTTGTAAA
AAAATAGCTAATCCTTTCGG

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRRTLSVLLENESGALSRVVGLFSQRGFNIESLTVAPTDDETLSRMTIVAQGDENVLEQIEKQLHKLIDVFKVSNLSPTE
HIEREVLLLKVRATGSSRDELKRMVDIFRGQIVDITPKLYTVQLAGTSEKLNAFIEAVKQETTIVEIVRSGVISLSRGDK
NCL

Sequences:

>Translated_163_residues
MRRTLSVLLENESGALSRVVGLFSQRGFNIESLTVAPTDDETLSRMTIVAQGDENVLEQIEKQLHKLIDVFKVSNLSPTE
HIEREVLLLKVRATGSSRDELKRMVDIFRGQIVDITPKLYTVQLAGTSEKLNAFIEAVKQETTIVEIVRSGVISLSRGDK
NCL
>Mature_163_residues
MRRTLSVLLENESGALSRVVGLFSQRGFNIESLTVAPTDDETLSRMTIVAQGDENVLEQIEKQLHKLIDVFKVSNLSPTE
HIEREVLLLKVRATGSSRDELKRMVDIFRGQIVDITPKLYTVQLAGTSEKLNAFIEAVKQETTIVEIVRSGVISLSRGDK
NCL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=160, Percent_Identity=70.625, Blast_Score=237, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=27.3170731707317, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18196; Mature: 18196

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTLSVLLENESGALSRVVGLFSQRGFNIESLTVAPTDDETLSRMTIVAQGDENVLEQI
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHEEEEEECCCHHHHHHH
EKQLHKLIDVFKVSNLSPTEHIEREVLLLKVRATGSSRDELKRMVDIFRGQIVDITPKLY
HHHHHHHHHHHHCCCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCEE
TVQLAGTSEKLNAFIEAVKQETTIVEIVRSGVISLSRGDKNCL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCC
>Mature Secondary Structure
MRRTLSVLLENESGALSRVVGLFSQRGFNIESLTVAPTDDETLSRMTIVAQGDENVLEQI
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHEEEEEECCCHHHHHHH
EKQLHKLIDVFKVSNLSPTEHIEREVLLLKVRATGSSRDELKRMVDIFRGQIVDITPKLY
HHHHHHHHHHHHCCCCCHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCEE
TVQLAGTSEKLNAFIEAVKQETTIVEIVRSGVISLSRGDKNCL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]