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The map label for this gene is hsdS3

Identifier: 126208116

GI number: 126208116

Start: 722739

End: 723980

Strand: Direct

Name: hsdS3

Synonym: APL_0634

Alternate gene names: NA

Gene position: 722739-723980 (Clockwise)

Preceding gene: 126208115

Following gene: 126208117

Centisome position: 31.78

GC content: 34.86

Gene sequence:

>1242_bases
ATGGCGAAATTGGGTGATATTGCAGATATTGTAATGGGGCAGTCCCCTTCAAGCAGTGACGTGAATATGGAAAGAATAGG
CGACCCTTTATTAAATGGTCCAACAGAATTTACGAGTTTTTATCCAAGTCCTGTTCAATATACAGAGAAGGGTAAAAAAT
TTGCTGAAAAAGGCGATTTATTATTTTGTGTTCGTGGATCAACAACAGGGAGAATAAATTTTGCGGATCAAAAATATGCT
ATAGGGAGAGGTTTGGCGGCAATTCGTGGCAAAAATGGTTATCCGACAAAATTTATTGAATTAATTTTAAAAGATTGCTT
GGAGAGAATTTTACAATCTGCAACAGGTTCAACATTTCCTAATGTGAGCCAAGCTATGTTATTGGATTTAGATATTGGGG
ATTTTTCTCTTCCAGAAGCAATTAAAATTGCTGACATATTGGGAATAATAGATCATAAAATCCACCTCAACACCCAAACC
AACCAAACCCTAGAACAAATCGCCCAAGCGATTTTCAAAAGTTGGTTTGTGGATTTCGAGCCTGTCAAAGCCAAAATGCA
AGGTGGCAATCTCGCCGTAATGGAAGCCATTTCTGGTAAAAACAGCGAAGAATTACACCGCTTGCAAACCGAAAACCCAA
CCGAATACCAAAAACTCTGGGCAATCGCAGATGCATTCCCTGATGAAATTGGGGAAGATGGCATACCTGTGGGGTGGGAA
AATGTATATCTAAAAGATGTTTGTAATATCGTTTATGGTAAAAATTTACCAATAAAAAAATTACAAGAGTTTGGATATCC
TGTGTTCGGTGGCAATGGAATAATAGGATTTTATGAAAAATTCTTATATGAAGAGCCACACACTTTGGTTTCTTGTCGGG
GAGCAGCTTCGGGGAAAGTAATGTATTCTCAACCATATTCATTTGTAACTAATAATTCTCTAGTGATAGAACACTCAAAA
AGCTTTTTAAGTTACTTTTATATTTATGAAGCACTTAGAATACAAACTCTAGTTGAGTTAACAACAGGTTCTGCACAACC
ACAAATGACAATAGCAAATATGAATCCAGTTCAGATAATATTGCCTACTGATAAAATTCATAATTTATACACATCTCAAG
TTAAGTATCTCTATGAAAAGATTTATAGAAATAATTTAGAAAATGAGCAATTAGAAAAAATTAGAGATGAATTATTGCCA
AAATTACTAAACGGAGATTTATGTAATACAATGGATAATTGA

Upstream 100 bases:

>100_bases
CACCAACCCCATTACGCCATAAAAATCCCAACAACGGACGCACGCAGTGCGTCCCTACCAATCACGTTTTATAAGATTTT
AGGGAAATTTGGAGATGAAA

Downstream 100 bases:

>100_bases
GCTATTTGCTAAGTCTCCGAGATTTTCAGTTTATCAAGCACAGGTTGATGATGTTTTAAATAATCTTGAAAGAAATCCAA
CATTAAATATAGGAATTTGA

Product: putative type I restriction system specificity protein

Products: NA

Alternate protein names: S.HindVIIP; Type I restriction enzyme HindVIIP specificity protein; S protein [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAKLGDIADIVMGQSPSSSDVNMERIGDPLLNGPTEFTSFYPSPVQYTEKGKKFAEKGDLLFCVRGSTTGRINFADQKYA
IGRGLAAIRGKNGYPTKFIELILKDCLERILQSATGSTFPNVSQAMLLDLDIGDFSLPEAIKIADILGIIDHKIHLNTQT
NQTLEQIAQAIFKSWFVDFEPVKAKMQGGNLAVMEAISGKNSEELHRLQTENPTEYQKLWAIADAFPDEIGEDGIPVGWE
NVYLKDVCNIVYGKNLPIKKLQEFGYPVFGGNGIIGFYEKFLYEEPHTLVSCRGAASGKVMYSQPYSFVTNNSLVIEHSK
SFLSYFYIYEALRIQTLVELTTGSAQPQMTIANMNPVQIILPTDKIHNLYTSQVKYLYEKIYRNNLENEQLEKIRDELLP
KLLNGDLCNTMDN

Sequences:

>Translated_413_residues
MAKLGDIADIVMGQSPSSSDVNMERIGDPLLNGPTEFTSFYPSPVQYTEKGKKFAEKGDLLFCVRGSTTGRINFADQKYA
IGRGLAAIRGKNGYPTKFIELILKDCLERILQSATGSTFPNVSQAMLLDLDIGDFSLPEAIKIADILGIIDHKIHLNTQT
NQTLEQIAQAIFKSWFVDFEPVKAKMQGGNLAVMEAISGKNSEELHRLQTENPTEYQKLWAIADAFPDEIGEDGIPVGWE
NVYLKDVCNIVYGKNLPIKKLQEFGYPVFGGNGIIGFYEKFLYEEPHTLVSCRGAASGKVMYSQPYSFVTNNSLVIEHSK
SFLSYFYIYEALRIQTLVELTTGSAQPQMTIANMNPVQIILPTDKIHNLYTSQVKYLYEKIYRNNLENEQLEKIRDELLP
KLLNGDLCNTMDN
>Mature_412_residues
AKLGDIADIVMGQSPSSSDVNMERIGDPLLNGPTEFTSFYPSPVQYTEKGKKFAEKGDLLFCVRGSTTGRINFADQKYAI
GRGLAAIRGKNGYPTKFIELILKDCLERILQSATGSTFPNVSQAMLLDLDIGDFSLPEAIKIADILGIIDHKIHLNTQTN
QTLEQIAQAIFKSWFVDFEPVKAKMQGGNLAVMEAISGKNSEELHRLQTENPTEYQKLWAIADAFPDEIGEDGIPVGWEN
VYLKDVCNIVYGKNLPIKKLQEFGYPVFGGNGIIGFYEKFLYEEPHTLVSCRGAASGKVMYSQPYSFVTNNSLVIEHSKS
FLSYFYIYEALRIQTLVELTTGSAQPQMTIANMNPVQIILPTDKIHNLYTSQVKYLYEKIYRNNLENEQLEKIRDELLPK
LLNGDLCNTMDN

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 46322; Mature: 46190

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLGDIADIVMGQSPSSSDVNMERIGDPLLNGPTEFTSFYPSPVQYTEKGKKFAEKGDL
CCCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCE
LFCVRGSTTGRINFADQKYAIGRGLAAIRGKNGYPTKFIELILKDCLERILQSATGSTFP
EEEEECCCCCEEEECCCHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
NVSQAMLLDLDIGDFSLPEAIKIADILGIIDHKIHLNTQTNQTLEQIAQAIFKSWFVDFE
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCCCH
PVKAKMQGGNLAVMEAISGKNSEELHRLQTENPTEYQKLWAIADAFPDEIGEDGIPVGWE
HHHHEECCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
NVYLKDVCNIVYGKNLPIKKLQEFGYPVFGGNGIIGFYEKFLYEEPHTLVSCRGAASGKV
HHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCE
MYSQPYSFVTNNSLVIEHSKSFLSYFYIYEALRIQTLVELTTGSAQPQMTIANMNPVQII
EEECCCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
LPTDKIHNLYTSQVKYLYEKIYRNNLENEQLEKIRDELLPKLLNGDLCNTMDN
ECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure 
AKLGDIADIVMGQSPSSSDVNMERIGDPLLNGPTEFTSFYPSPVQYTEKGKKFAEKGDL
CCCCCHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCE
LFCVRGSTTGRINFADQKYAIGRGLAAIRGKNGYPTKFIELILKDCLERILQSATGSTFP
EEEEECCCCCEEEECCCHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
NVSQAMLLDLDIGDFSLPEAIKIADILGIIDHKIHLNTQTNQTLEQIAQAIFKSWFVDFE
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHCCCCH
PVKAKMQGGNLAVMEAISGKNSEELHRLQTENPTEYQKLWAIADAFPDEIGEDGIPVGWE
HHHHEECCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
NVYLKDVCNIVYGKNLPIKKLQEFGYPVFGGNGIIGFYEKFLYEEPHTLVSCRGAASGKV
HHHHHHHHHHHHCCCCCHHHHHHCCCCEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCE
MYSQPYSFVTNNSLVIEHSKSFLSYFYIYEALRIQTLVELTTGSAQPQMTIANMNPVQII
EEECCCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
LPTDKIHNLYTSQVKYLYEKIYRNNLENEQLEKIRDELLPKLLNGDLCNTMDN
ECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]