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The map label for this gene is fieF [H]

Identifier: 126208086

GI number: 126208086

Start: 689899

End: 690822

Strand: Direct

Name: fieF [H]

Synonym: APL_0604

Alternate gene names: 126208086

Gene position: 689899-690822 (Clockwise)

Preceding gene: 126208085

Following gene: 126208087

Centisome position: 30.33

GC content: 41.34

Gene sequence:

>924_bases
ATGGAACAGCAATATATAAAACTGGTAAAACGAGCGGCAAATTTAGCGATTACCATTGCTTGCGTATTAATTGTTATCAA
AATGTTTGCATGGTGGAAAACCGGCTCAATTTCGATTTTAGCGGCGGTAACCGATTCTGTTGTCGATTTATTAGCCTCGA
TCACTAATATTTTAGTGTTACGTTTTGCGCTTTTGCCGGCGGATGAAAACCATACTTTCGGGCATGGTAAAGCGGAATCT
TTGGCTGCGATTGCGCAAAGTGCGTTTATCGGCGGTTCGGCGGTGTTTCTAGTGCTGCAAGGCGTGCATAAATTGATGCA
TCCGCATTTTATTAACGGATCTGAAATCGGGATAATTGTCAGTCTGATTTCGATTGTTTTTACCGCCGGGTTAGTTTGGT
ACCAAAAGCGGGTGGTTGCATTAACTAAAAGTCCGGCGATTGCGGCGGATTCGCTCCATTATCAAACCGATTTATTAATG
AATGCGGCGATTTTAGCGGCAATGTTGCTTAATTTATACGGTTTTGTGTATGCCGATGCGATTTTTGCCATCGGAATTGC
ACTGTATATCGGTCTTAATGCGCTAAAAATGTTTTGGGAAGCGGTACAAGTGCTGCTGGATAAAGCGTTACCGCAAGAAG
AGATTGATCAAATTATCGAATTGGCGGCAAAACACGAACGAATTATCGGTATTCATGATTTACTGACACGTCAAGTGGGA
GCCGTGCGTTTTATCCAACTTCATTTGGAATTAGCCGATAATCTCACTTTAATTGAAGCGCATGATATTACCGATTCGTT
GGAACAAAAAATTCTGGCGATTTTTCCGCGTTCGGAAATTATTATTCATCAAGAACCGACCTCAATTGTTCAGCAAGAGC
TTAAATTAGGGCAAGTAAAAGATTATGTACCAAGTTATCGCTAA

Upstream 100 bases:

>100_bases
ACCGCTTACCAAGCTTCATTGCTTCAATTGGCACAGCAACTTGCGGCAATGCCGTGGTTAGTCACGTGTAAATAAACCGA
ATAGGGTATAAGGAAGGTGT

Downstream 100 bases:

>100_bases
TTTCAGTTATCAAAATTTTGAAAGCGATCCTGTCACGTTTATTAGTCAAATTGTTAATCAATGGCGTTTTAACGGGCAAA
TTATCGGGCGTGAATTTGCG

Product: cation-efflux pump FieF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEQQYIKLVKRAANLAITIACVLIVIKMFAWWKTGSISILAAVTDSVVDLLASITNILVLRFALLPADENHTFGHGKAES
LAAIAQSAFIGGSAVFLVLQGVHKLMHPHFINGSEIGIIVSLISIVFTAGLVWYQKRVVALTKSPAIAADSLHYQTDLLM
NAAILAAMLLNLYGFVYADAIFAIGIALYIGLNALKMFWEAVQVLLDKALPQEEIDQIIELAAKHERIIGIHDLLTRQVG
AVRFIQLHLELADNLTLIEAHDITDSLEQKILAIFPRSEIIIHQEPTSIVQQELKLGQVKDYVPSYR

Sequences:

>Translated_307_residues
MEQQYIKLVKRAANLAITIACVLIVIKMFAWWKTGSISILAAVTDSVVDLLASITNILVLRFALLPADENHTFGHGKAES
LAAIAQSAFIGGSAVFLVLQGVHKLMHPHFINGSEIGIIVSLISIVFTAGLVWYQKRVVALTKSPAIAADSLHYQTDLLM
NAAILAAMLLNLYGFVYADAIFAIGIALYIGLNALKMFWEAVQVLLDKALPQEEIDQIIELAAKHERIIGIHDLLTRQVG
AVRFIQLHLELADNLTLIEAHDITDSLEQKILAIFPRSEIIIHQEPTSIVQQELKLGQVKDYVPSYR
>Mature_307_residues
MEQQYIKLVKRAANLAITIACVLIVIKMFAWWKTGSISILAAVTDSVVDLLASITNILVLRFALLPADENHTFGHGKAES
LAAIAQSAFIGGSAVFLVLQGVHKLMHPHFINGSEIGIIVSLISIVFTAGLVWYQKRVVALTKSPAIAADSLHYQTDLLM
NAAILAAMLLNLYGFVYADAIFAIGIALYIGLNALKMFWEAVQVLLDKALPQEEIDQIIELAAKHERIIGIHDLLTRQVG
AVRFIQLHLELADNLTLIEAHDITDSLEQKILAIFPRSEIIIHQEPTSIVQQELKLGQVKDYVPSYR

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=295, Percent_Identity=53.5593220338983, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI72000060, Length=290, Percent_Identity=24.4827586206897, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000062, Length=290, Percent_Identity=24.4827586206897, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33849; Mature: 33849

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQQYIKLVKRAANLAITIACVLIVIKMFAWWKTGSISILAAVTDSVVDLLASITNILVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RFALLPADENHTFGHGKAESLAAIAQSAFIGGSAVFLVLQGVHKLMHPHFINGSEIGIIV
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SLISIVFTAGLVWYQKRVVALTKSPAIAADSLHYQTDLLMNAAILAAMLLNLYGFVYADA
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAIGIALYIGLNALKMFWEAVQVLLDKALPQEEIDQIIELAAKHERIIGIHDLLTRQVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRFIQLHLELADNLTLIEAHDITDSLEQKILAIFPRSEIIIHQEPTSIVQQELKLGQVK
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
DYVPSYR
HHCCCCC
>Mature Secondary Structure
MEQQYIKLVKRAANLAITIACVLIVIKMFAWWKTGSISILAAVTDSVVDLLASITNILVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RFALLPADENHTFGHGKAESLAAIAQSAFIGGSAVFLVLQGVHKLMHPHFINGSEIGIIV
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SLISIVFTAGLVWYQKRVVALTKSPAIAADSLHYQTDLLMNAAILAAMLLNLYGFVYADA
HHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFAIGIALYIGLNALKMFWEAVQVLLDKALPQEEIDQIIELAAKHERIIGIHDLLTRQVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVRFIQLHLELADNLTLIEAHDITDSLEQKILAIFPRSEIIIHQEPTSIVQQELKLGQVK
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
DYVPSYR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA