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The map label for this gene is sotB [H]

Identifier: 126208064

GI number: 126208064

Start: 662052

End: 663227

Strand: Direct

Name: sotB [H]

Synonym: APL_0582

Alternate gene names: 126208064

Gene position: 662052-663227 (Clockwise)

Preceding gene: 126208063

Following gene: 126208067

Centisome position: 29.11

GC content: 42.18

Gene sequence:

>1176_bases
ATGATTACCAGAAAAGAACATCGCAAACTTTCGTTTTTGCGAGTGTTTGTGTTTTCACTGTCCGCATTTATTTTTAATAC
CACGGAGTTTATCCCCGTAGCACTGTTATCGGATATTGCGGTTAGCTTTGAGATGGAAACGGCAACGACAGGATTAATGA
TTACCGCTTATGCGTGGGTGGTTTTTTTAGCGGCATTACCTTTTATGTTACTGACGGCAAAAGTAGAACGAAAGCGTTTA
TTGCTAGTGTTGTTTGCGATATTTATTGTGGGACATATCGTCTCATATTTTGCCACCAGCTTTACCATGTTGTTGATTTC
CCGAATGGGGATTGCTTTGACCCATGCTATTTTCTGGTCAATTACCGCTTCACTGGTCATTCGTGTTGCACCGAAAGATA
AAAAACAGCAAGCGTTAGGACTATTAGCCCTAGGCAATTCATTAGCGATGATTTTCGGTCTGCCGTTAGGGCGAATGATC
GGGCAAGCGTTCGGTTGGCGTGAAACGTTTGCTCTCATTGGTATCATTGCGTTGGGTATTATGTTGATTATGTGGAAGTT
ACTACCGCATTTACCAAGCAAAAATTCGGGATCGTTAGCCGGCTTGCCGATTTTAATTAAGCGTCCGATGCTAGTTGGTA
TCTACTTATTGACAGCGGTTGTTATTTCCGGACATTTTACCGGCTATAGTTATATTGAGCCGTTTATGGTGAAGATCAGC
CAAATGAGTGAACAAACCGGCACGGCAATTTTATTAGTGTTCGGCTTGGCCGGTGTGGCGGCAAGTTTCTTATTCGGGCG
TTTATATCCGAAAGCACCGAAGAAATTTATTATCAGCAATATGGCATTAATTATGCTAATGCAGATGTGCCTATTACCAT
TTAGTAATCATATTGCGGCGATGTTCGGCATAGTGTTTATTTGGGGAATTGGTATTACCGCAATGAGTATCGCATTGCAA
ATGCAAGTATTGGATCTCGCACCGGATGCGACTGATGTGGCAACGGCAATTTATTCGGGGATTTATAATGTCGGTATCGG
TGGCGGCGCATTAATCGGTAGCCAAGTGATTCAGCATATCGGTTTGCCTTATATCGGATGGATTGGCGGCGGATTGGCAG
GTTTTGCTATTTTATGGTTTGTATTTATTTCTTTACGTTATCGTGTAATAAAATAG

Upstream 100 bases:

>100_bases
TTGAAAGGGTTTGGGCAACAATAAAGCGTGAACTTACAAGCGGTCAGAAATTGCAAAAAAGTTGCAAAATCTGACCGCTT
AATTTTTTAGGAAGAATAAA

Downstream 100 bases:

>100_bases
CTTAGGCACAATAAAAGAAAATGGGATTGTTATCCCATTTTCAGTTACCGCTTATTTCTCAACAAATTGATTACTTTGTT
GGATCATATGTAAGAAGAGT

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MITRKEHRKLSFLRVFVFSLSAFIFNTTEFIPVALLSDIAVSFEMETATTGLMITAYAWVVFLAALPFMLLTAKVERKRL
LLVLFAIFIVGHIVSYFATSFTMLLISRMGIALTHAIFWSITASLVIRVAPKDKKQQALGLLALGNSLAMIFGLPLGRMI
GQAFGWRETFALIGIIALGIMLIMWKLLPHLPSKNSGSLAGLPILIKRPMLVGIYLLTAVVISGHFTGYSYIEPFMVKIS
QMSEQTGTAILLVFGLAGVAASFLFGRLYPKAPKKFIISNMALIMLMQMCLLPFSNHIAAMFGIVFIWGIGITAMSIALQ
MQVLDLAPDATDVATAIYSGIYNVGIGGGALIGSQVIQHIGLPYIGWIGGGLAGFAILWFVFISLRYRVIK

Sequences:

>Translated_391_residues
MITRKEHRKLSFLRVFVFSLSAFIFNTTEFIPVALLSDIAVSFEMETATTGLMITAYAWVVFLAALPFMLLTAKVERKRL
LLVLFAIFIVGHIVSYFATSFTMLLISRMGIALTHAIFWSITASLVIRVAPKDKKQQALGLLALGNSLAMIFGLPLGRMI
GQAFGWRETFALIGIIALGIMLIMWKLLPHLPSKNSGSLAGLPILIKRPMLVGIYLLTAVVISGHFTGYSYIEPFMVKIS
QMSEQTGTAILLVFGLAGVAASFLFGRLYPKAPKKFIISNMALIMLMQMCLLPFSNHIAAMFGIVFIWGIGITAMSIALQ
MQVLDLAPDATDVATAIYSGIYNVGIGGGALIGSQVIQHIGLPYIGWIGGGLAGFAILWFVFISLRYRVIK
>Mature_391_residues
MITRKEHRKLSFLRVFVFSLSAFIFNTTEFIPVALLSDIAVSFEMETATTGLMITAYAWVVFLAALPFMLLTAKVERKRL
LLVLFAIFIVGHIVSYFATSFTMLLISRMGIALTHAIFWSITASLVIRVAPKDKKQQALGLLALGNSLAMIFGLPLGRMI
GQAFGWRETFALIGIIALGIMLIMWKLLPHLPSKNSGSLAGLPILIKRPMLVGIYLLTAVVISGHFTGYSYIEPFMVKIS
QMSEQTGTAILLVFGLAGVAASFLFGRLYPKAPKKFIISNMALIMLMQMCLLPFSNHIAAMFGIVFIWGIGITAMSIALQ
MQVLDLAPDATDVATAIYSGIYNVGIGGGALIGSQVIQHIGLPYIGWIGGGLAGFAILWFVFISLRYRVIK

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=389, Percent_Identity=51.413881748072, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1787947, Length=377, Percent_Identity=29.4429708222812, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693198, Length=339, Percent_Identity=27.4336283185841, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786595, Length=347, Percent_Identity=26.5129682997118, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42743; Mature: 42743

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITRKEHRKLSFLRVFVFSLSAFIFNTTEFIPVALLSDIAVSFEMETATTGLMITAYAWV
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHH
VFLAALPFMLLTAKVERKRLLLVLFAIFIVGHIVSYFATSFTMLLISRMGIALTHAIFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLVIRVAPKDKKQQALGLLALGNSLAMIFGLPLGRMIGQAFGWRETFALIGIIALGI
HHHHHHEEECCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHH
MLIMWKLLPHLPSKNSGSLAGLPILIKRPMLVGIYLLTAVVISGHFTGYSYIEPFMVKIS
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QMSEQTGTAILLVFGLAGVAASFLFGRLYPKAPKKFIISNMALIMLMQMCLLPFSNHIAA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
MFGIVFIWGIGITAMSIALQMQVLDLAPDATDVATAIYSGIYNVGIGGGALIGSQVIQHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GLPYIGWIGGGLAGFAILWFVFISLRYRVIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITRKEHRKLSFLRVFVFSLSAFIFNTTEFIPVALLSDIAVSFEMETATTGLMITAYAWV
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHH
VFLAALPFMLLTAKVERKRLLLVLFAIFIVGHIVSYFATSFTMLLISRMGIALTHAIFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITASLVIRVAPKDKKQQALGLLALGNSLAMIFGLPLGRMIGQAFGWRETFALIGIIALGI
HHHHHHEEECCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHH
MLIMWKLLPHLPSKNSGSLAGLPILIKRPMLVGIYLLTAVVISGHFTGYSYIEPFMVKIS
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QMSEQTGTAILLVFGLAGVAASFLFGRLYPKAPKKFIISNMALIMLMQMCLLPFSNHIAA
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
MFGIVFIWGIGITAMSIALQMQVLDLAPDATDVATAIYSGIYNVGIGGGALIGSQVIQHI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GLPYIGWIGGGLAGFAILWFVFISLRYRVIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA