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The map label for this gene is mtnC [H]

Identifier: 126176449

GI number: 126176449

Start: 4992698

End: 4993378

Strand: Direct

Name: mtnC [H]

Synonym: Sbal_4264

Alternate gene names: 126176449

Gene position: 4992698-4993378 (Clockwise)

Preceding gene: 126176445

Following gene: 126176454

Centisome position: 97.37

GC content: 45.37

Gene sequence:

>681_bases
ATGGGTATCAGAGCCATAGTCGTAGACACAGCAGGCACCACGACAGACCTAAACTTTATCCAAGATGTACTATTCCCCTA
TTCTGTCAAAGCCTTGCCAGACTTTTTAGAACAGAACCAACACAATGTATTGGTTGAAAACTGTATTTGCGACACCCGAG
ATATCGCCCTAGAGCCAGATGCGGACTTAGCACGCGTGACTGAAATTTTGCAGCAGTGGGTCAGCGAAGATCGTAAAGCG
ACACCACTCAAAACCCTGCAAGGCTTGATCTGGAAGCAAGGCTACGCCCATGGCGAATTTAAGGGCCATATCTTCCCTGA
CTTTATTGAAGCGGTGAAACGTTTTAGCGCGCAAAATTTGCGTATTTACAGTTTTTCATCGGGCTCTGTTGATGCGCAAA
AACTGTTATTCAGCCACAGTGACGGCGGCGATTTAACCGAGATGTTCAACGGTCATTTTGATACCCGTACAGGCAACAAA
TTAGATAAACAGGCTTACTGCAATATCCTCAACACTATCAGCTTAAGCCCTAAGCAAGTGCTATTTGTGTCTGATGTGAT
TGAAGAATTAAAGGCTGCAGAAGCTGCAGGCATGATGACCTGTCAAATGGTACGCGATAGCACACTGCGCACTGGTGAGT
TCCGTAAAATCAGCAGCTTTGATGAGTTGCTGATTGAATAA

Upstream 100 bases:

>100_bases
GCCCATGTGTTTGGGCGAAATAGACTAGCCAATTTCGCCAATAACGCTTAGGATCGGAGTTGCATTTTTAAGCCAACATA
TTGTGGAGTATCAAAACATT

Downstream 100 bases:

>100_bases
CGTGATTGTTGAAGAACGCAATAGTCGACTAACTCAGCCAAACTGATTTAGCAAAAAATGAAAGCGACCTTGTGGTCGCT
TTTTTATGGGTCTGCTTATT

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKA
TPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSAQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNK
LDKQAYCNILNTISLSPKQVLFVSDVIEELKAAEAAGMMTCQMVRDSTLRTGEFRKISSFDELLIE

Sequences:

>Translated_226_residues
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKA
TPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSAQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNK
LDKQAYCNILNTISLSPKQVLFVSDVIEELKAAEAAGMMTCQMVRDSTLRTGEFRKISSFDELLIE
>Mature_225_residues
GIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVSEDRKAT
PLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSAQNLRIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKL
DKQAYCNILNTISLSPKQVLFVSDVIEELKAAEAAGMMTCQMVRDSTLRTGEFRKISSFDELLIE

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=254, Percent_Identity=35.0393700787402, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI115533232, Length=215, Percent_Identity=38.1395348837209, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320797, Length=208, Percent_Identity=34.1346153846154, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281360080, Length=213, Percent_Identity=37.0892018779343, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24644163, Length=213, Percent_Identity=37.0892018779343, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 25374; Mature: 25243

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPD
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCC
ADLARVTEILQQWVSEDRKATPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSAQNL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCE
RIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKLDKQAYCNILNTISLSPKQV
EEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LFVSDVIEELKAAEAAGMMTCQMVRDSTLRTGEFRKISSFDELLIE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GIRAIVVDTAGTTTDLNFIQDVLFPYSVKALPDFLEQNQHNVLVENCICDTRDIALEPD
CCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCCC
ADLARVTEILQQWVSEDRKATPLKTLQGLIWKQGYAHGEFKGHIFPDFIEAVKRFSAQNL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCE
RIYSFSSGSVDAQKLLFSHSDGGDLTEMFNGHFDTRTGNKLDKQAYCNILNTISLSPKQV
EEEEECCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
LFVSDVIEELKAAEAAGMMTCQMVRDSTLRTGEFRKISSFDELLIE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA