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The map label for this gene is yciR [C]

Identifier: 126176406

GI number: 126176406

Start: 4947128

End: 4949329

Strand: Direct

Name: yciR [C]

Synonym: Sbal_4221

Alternate gene names: 126176406

Gene position: 4947128-4949329 (Clockwise)

Preceding gene: 126176405

Following gene: 126176408

Centisome position: 96.48

GC content: 49.41

Gene sequence:

>2202_bases
ATGGCCAAGCTGCTGCAATTGAAGCAGCAAGGCTTGCCGATGGCGGAGATCAACGCCATCGCGCAAGTCCCTGCCAGTGA
GGACAAGTTAAGCCAAGCGATGACACAACTGCTAATGCCGCCACATCCGATTGACAGCCAAAAATGGTGGGCGCTCACCA
CCCAGCGTATTGAACAACTGCATCAACTCGCCAAAGACATCACCCAGACCATGGCGCAGCAGAGCGAGTATCAACAAAAC
CAAGCCCTGACCTTCCTCGGCCTGTACTTGTCATCAGCGCTGTTCACCGCAACCGTTACACTCTGGCTCGGACAGAAGAT
CATTCGCAACTTTATGGATAAAATCACTAAGATTGCCAATGACATGCAGCAAATGGCGGAAGATCCTAAGCTCAATATCA
ATATCCGCGTTTCAGGTACTGATGAACTTGCTCGCATGGCCCGTGCCATGAACCGGATGATCAGCGAGCGGCAGAAGGCG
AACCATGCGCTCACCCGCGCCGCTGCGGTATTTGACTATTCTGCCGAGGGCATAATGGTGACTGATGCCGATAACCATAT
CGAACTGGTCAATCCGGCTTTCTGCAATATTACTGGCTATACATTGGAAGAGGTGAAAGGCCGCAGCCCATCCATCCTCA
GTTCTAGCCGCCATTCGCAGCACTTTTACACCACCATGTGGGAGTCGCTGCAAACAGAAGGAAAATGGGAGGGCGAGGTT
TGGAATAAGCGCAAAAATGGCCAAGTGTATCCCGAGTATTTAGCCATTACTGTGGTGCGAAATGAGCAAGGACAAATAAT
CCAACACATTGGTTTATTTATGGATATCAGTAAGCGTAAGCAATATGAGCAAGATCTTTGGTATCAAGCCAACTTCGATG
CGTTAACGGGACTGCCTAATCGTAAGTTGTTTAATGAGCGCCTACAGCACGAAATCCATGTGGCGCAGCATGACTCACGC
AAACTGGCGATTCTGCTGATAGATTTAGACCAATTCAAATACATCAACGATGTGCAAGGCCATGCCACGGGCGACTTATT
ACTTAAAGATGTGGCCAAACGCTTAGAAGGCATTGCGGGTAAAACCGACTTTATCGCCCGCATCGGGGGTGATGAATTTG
TGCTTATATTGCCTCGACTGACTAACGAACTCGCCATCGAACACATGGCAACGCGTATTATCGAAACCTTAGGCATGCCG
TTTGACTTAAATGACCGCGAGATCCAGATTTCAGCCAGCTTTGGTATCGGCGTCTATCCCGAAGATGGCCTCGATGTCAG
CTCACTCACCCGCAATACCGAAACCGCCATGTATCAAGCCAAAGATGCGGGACGGAACAACTTCAAATACTTTACCGCGG
GCATGAATGAAGCCATGTTCGCTCGGATGGAGTTAGAGCAACGCCTGCGCCGCGCCGTGGCACAAAATGAATTTGCCCTG
CATTATCAACCCATAGTGGATATGCAAACTGGAGTCGTCTGTAGCGTCGAAGCCCTTATCCGCTGGCAAGATCCTGACTT
TGGCCTGATCCCACCGGATCAATTTATCCCGCTGGCCGAAGAAACCGGACTGATAGAACCTATGGGCGAATGGGTGCTCA
ACCAAGCCATGCATGATTTGAGACAGTGGCAGAAAAGTGGCTTAAAAATCAATGTTGCGATTAATGTTTCTGGCCGCCAA
TGTATCAACACCCGCGGCATGGGATTCGACCAAGTGCTGCAGGAATGCTTTAACCGCCACCATGTGAACCCGCGCAATGT
GCATATTGAGATCACAGAAAGCATGCTGATGGGCGATGCCAGCCACTGCTTGAGCACGCTCGAATCGATTCGCCATTTAG
GCTCGCAAATCTATATCGATGACTTTGGTACGGGTTATTCTTCCCTGAGTTATTTGAAAAAATTCCCTATCTCAGTGATT
AAAATTGATCGTAGCTTTGTGGAAAATGCCCTCGAAAGTAACGCTAATGCTAACTTAGTCAAAGCCATCGTCATGATGGG
GCAAAGCCTCGAAATGGAGTTAGTGGCCGAAGGCATAGAAACCGAGGCCCAGTGGCACTTCCTGCGGGATTTAGGTTGTC
ACTTTGCCCAAGGATATTTGATCTCTAAACCGCTGCCCTTCGACGAGATCACCCCCTTGCTGCACATCAAGCACACAGCA
CTGCTCAACCACGATTACCAAGATAGATGCGTGAATATCTAA

Upstream 100 bases:

>100_bases
TCTCAACTTAGATGAACTCAATCACGAGACCCACTTTCTCCCCAAATTTAAGCCGGCGCTGAAAACCATTGAGGACAGCA
TAGATCAATACCAGTTCAGC

Downstream 100 bases:

>100_bases
GATGCTGAAAGCTAGTCATCAATAACAAAAAAGCAGCCTAGGCTGCTTTTTTGTGGCGAATAAAACGAGCTTAAGCCTGC
GGTTGGCCTTGACCGTTCAT

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MAKLLQLKQQGLPMAEINAIAQVPASEDKLSQAMTQLLMPPHPIDSQKWWALTTQRIEQLHQLAKDITQTMAQQSEYQQN
QALTFLGLYLSSALFTATVTLWLGQKIIRNFMDKITKIANDMQQMAEDPKLNINIRVSGTDELARMARAMNRMISERQKA
NHALTRAAAVFDYSAEGIMVTDADNHIELVNPAFCNITGYTLEEVKGRSPSILSSSRHSQHFYTTMWESLQTEGKWEGEV
WNKRKNGQVYPEYLAITVVRNEQGQIIQHIGLFMDISKRKQYEQDLWYQANFDALTGLPNRKLFNERLQHEIHVAQHDSR
KLAILLIDLDQFKYINDVQGHATGDLLLKDVAKRLEGIAGKTDFIARIGGDEFVLILPRLTNELAIEHMATRIIETLGMP
FDLNDREIQISASFGIGVYPEDGLDVSSLTRNTETAMYQAKDAGRNNFKYFTAGMNEAMFARMELEQRLRRAVAQNEFAL
HYQPIVDMQTGVVCSVEALIRWQDPDFGLIPPDQFIPLAEETGLIEPMGEWVLNQAMHDLRQWQKSGLKINVAINVSGRQ
CINTRGMGFDQVLQECFNRHHVNPRNVHIEITESMLMGDASHCLSTLESIRHLGSQIYIDDFGTGYSSLSYLKKFPISVI
KIDRSFVENALESNANANLVKAIVMMGQSLEMELVAEGIETEAQWHFLRDLGCHFAQGYLISKPLPFDEITPLLHIKHTA
LLNHDYQDRCVNI

Sequences:

>Translated_733_residues
MAKLLQLKQQGLPMAEINAIAQVPASEDKLSQAMTQLLMPPHPIDSQKWWALTTQRIEQLHQLAKDITQTMAQQSEYQQN
QALTFLGLYLSSALFTATVTLWLGQKIIRNFMDKITKIANDMQQMAEDPKLNINIRVSGTDELARMARAMNRMISERQKA
NHALTRAAAVFDYSAEGIMVTDADNHIELVNPAFCNITGYTLEEVKGRSPSILSSSRHSQHFYTTMWESLQTEGKWEGEV
WNKRKNGQVYPEYLAITVVRNEQGQIIQHIGLFMDISKRKQYEQDLWYQANFDALTGLPNRKLFNERLQHEIHVAQHDSR
KLAILLIDLDQFKYINDVQGHATGDLLLKDVAKRLEGIAGKTDFIARIGGDEFVLILPRLTNELAIEHMATRIIETLGMP
FDLNDREIQISASFGIGVYPEDGLDVSSLTRNTETAMYQAKDAGRNNFKYFTAGMNEAMFARMELEQRLRRAVAQNEFAL
HYQPIVDMQTGVVCSVEALIRWQDPDFGLIPPDQFIPLAEETGLIEPMGEWVLNQAMHDLRQWQKSGLKINVAINVSGRQ
CINTRGMGFDQVLQECFNRHHVNPRNVHIEITESMLMGDASHCLSTLESIRHLGSQIYIDDFGTGYSSLSYLKKFPISVI
KIDRSFVENALESNANANLVKAIVMMGQSLEMELVAEGIETEAQWHFLRDLGCHFAQGYLISKPLPFDEITPLLHIKHTA
LLNHDYQDRCVNI
>Mature_732_residues
AKLLQLKQQGLPMAEINAIAQVPASEDKLSQAMTQLLMPPHPIDSQKWWALTTQRIEQLHQLAKDITQTMAQQSEYQQNQ
ALTFLGLYLSSALFTATVTLWLGQKIIRNFMDKITKIANDMQQMAEDPKLNINIRVSGTDELARMARAMNRMISERQKAN
HALTRAAAVFDYSAEGIMVTDADNHIELVNPAFCNITGYTLEEVKGRSPSILSSSRHSQHFYTTMWESLQTEGKWEGEVW
NKRKNGQVYPEYLAITVVRNEQGQIIQHIGLFMDISKRKQYEQDLWYQANFDALTGLPNRKLFNERLQHEIHVAQHDSRK
LAILLIDLDQFKYINDVQGHATGDLLLKDVAKRLEGIAGKTDFIARIGGDEFVLILPRLTNELAIEHMATRIIETLGMPF
DLNDREIQISASFGIGVYPEDGLDVSSLTRNTETAMYQAKDAGRNNFKYFTAGMNEAMFARMELEQRLRRAVAQNEFALH
YQPIVDMQTGVVCSVEALIRWQDPDFGLIPPDQFIPLAEETGLIEPMGEWVLNQAMHDLRQWQKSGLKINVAINVSGRQC
INTRGMGFDQVLQECFNRHHVNPRNVHIEITESMLMGDASHCLSTLESIRHLGSQIYIDDFGTGYSSLSYLKKFPISVIK
IDRSFVENALESNANANLVKAIVMMGQSLEMELVAEGIETEAQWHFLRDLGCHFAQGYLISKPLPFDEITPLLHIKHTAL
LNHDYQDRCVNI

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=555, Percent_Identity=36.036036036036, Blast_Score=338, Evalue=8e-94,
Organism=Escherichia coli, GI87081921, Length=448, Percent_Identity=32.8125, Blast_Score=243, Evalue=4e-65,
Organism=Escherichia coli, GI226510982, Length=451, Percent_Identity=27.7161862527716, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI87081743, Length=299, Percent_Identity=35.1170568561873, Blast_Score=180, Evalue=4e-46,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=31.5352697095436, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1786507, Length=266, Percent_Identity=33.8345864661654, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI87081980, Length=248, Percent_Identity=34.2741935483871, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1788502, Length=264, Percent_Identity=32.5757575757576, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=33.203125, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1787055, Length=246, Percent_Identity=32.520325203252, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788849, Length=266, Percent_Identity=31.5789473684211, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788381, Length=574, Percent_Identity=22.4738675958188, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=261, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=34.6153846153846, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081977, Length=180, Percent_Identity=36.1111111111111, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788956, Length=151, Percent_Identity=36.4238410596026, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693134, Length=200, Percent_Identity=29.5, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=30.0578034682081, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082007, Length=173, Percent_Identity=34.1040462427746, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=30.6748466257669, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=31.2101910828025, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789650, Length=426, Percent_Identity=21.3615023474178, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081974, Length=93, Percent_Identity=36.5591397849462, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787410, Length=120, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 83352; Mature: 83220

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50937 HTH_MERR_2 ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLLQLKQQGLPMAEINAIAQVPASEDKLSQAMTQLLMPPHPIDSQKWWALTTQRIEQL
CCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HQLAKDITQTMAQQSEYQQNQALTFLGLYLSSALFTATVTLWLGQKIIRNFMDKITKIAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMQQMAEDPKLNINIRVSGTDELARMARAMNRMISERQKANHALTRAAAVFDYSAEGIMV
HHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
TDADNHIELVNPAFCNITGYTLEEVKGRSPSILSSSRHSQHFYTTMWESLQTEGKWEGEV
ECCCCCEEEECCCEECCCCCCHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHH
WNKRKNGQVYPEYLAITVVRNEQGQIIQHIGLFMDISKRKQYEQDLWYQANFDALTGLPN
HCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHCCCCC
RKLFNERLQHEIHVAQHDSRKLAILLIDLDQFKYINDVQGHATGDLLLKDVAKRLEGIAG
HHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
KTDFIARIGGDEFVLILPRLTNELAIEHMATRIIETLGMPFDLNDREIQISASFGIGVYP
CCHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCC
EDGLDVSSLTRNTETAMYQAKDAGRNNFKYFTAGMNEAMFARMELEQRLRRAVAQNEFAL
CCCCCHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEE
HYQPIVDMQTGVVCSVEALIRWQDPDFGLIPPDQFIPLAEETGLIEPMGEWVLNQAMHDL
EECCCCCCCCCCEEEEEHHEEECCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
RQWQKSGLKINVAINVSGRQCINTRGMGFDQVLQECFNRHHVNPRNVHIEITESMLMGDA
HHHHHCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCH
SHCLSTLESIRHLGSQIYIDDFGTGYSSLSYLKKFPISVIKIDRSFVENALESNANANLV
HHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHH
KAIVMMGQSLEMELVAEGIETEAQWHFLRDLGCHFAQGYLISKPLPFDEITPLLHIKHTA
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHCCHHHHHHHHH
LLNHDYQDRCVNI
HHCCCHHHHHCCC
>Mature Secondary Structure 
AKLLQLKQQGLPMAEINAIAQVPASEDKLSQAMTQLLMPPHPIDSQKWWALTTQRIEQL
CHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HQLAKDITQTMAQQSEYQQNQALTFLGLYLSSALFTATVTLWLGQKIIRNFMDKITKIAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMQQMAEDPKLNINIRVSGTDELARMARAMNRMISERQKANHALTRAAAVFDYSAEGIMV
HHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
TDADNHIELVNPAFCNITGYTLEEVKGRSPSILSSSRHSQHFYTTMWESLQTEGKWEGEV
ECCCCCEEEECCCEECCCCCCHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHH
WNKRKNGQVYPEYLAITVVRNEQGQIIQHIGLFMDISKRKQYEQDLWYQANFDALTGLPN
HCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHCCCCC
RKLFNERLQHEIHVAQHDSRKLAILLIDLDQFKYINDVQGHATGDLLLKDVAKRLEGIAG
HHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
KTDFIARIGGDEFVLILPRLTNELAIEHMATRIIETLGMPFDLNDREIQISASFGIGVYP
CCHHHEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCC
EDGLDVSSLTRNTETAMYQAKDAGRNNFKYFTAGMNEAMFARMELEQRLRRAVAQNEFAL
CCCCCHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEE
HYQPIVDMQTGVVCSVEALIRWQDPDFGLIPPDQFIPLAEETGLIEPMGEWVLNQAMHDL
EECCCCCCCCCCEEEEEHHEEECCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
RQWQKSGLKINVAINVSGRQCINTRGMGFDQVLQECFNRHHVNPRNVHIEITESMLMGDA
HHHHHCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCH
SHCLSTLESIRHLGSQIYIDDFGTGYSSLSYLKKFPISVIKIDRSFVENALESNANANLV
HHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHH
KAIVMMGQSLEMELVAEGIETEAQWHFLRDLGCHFAQGYLISKPLPFDEITPLLHIKHTA
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCCHHHCCHHHHHHHHH
LLNHDYQDRCVNI
HHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]