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The map label for this gene is pilQ [H]

Identifier: 126176299

GI number: 126176299

Start: 4821445

End: 4823496

Strand: Reverse

Name: pilQ [H]

Synonym: Sbal_4114

Alternate gene names: 126176299

Gene position: 4823496-4821445 (Counterclockwise)

Preceding gene: 126176300

Following gene: 126176298

Centisome position: 94.07

GC content: 43.91

Gene sequence:

>2052_bases
ATGAAATCTTCTGCCGCGATAAAAGTCCCGTTATTATCTTCAGGCTTAATCAAGTCTGTCATAGGGATCGCACTGGTATT
TGGAATTTTGCCATCGAGTTTTGCGGCAAATCGATTAATGGATGTGAAATACCACGCCTTGGTTGACCATCAATTGGAGC
TAGAGCTGGTCTTTGAAGAGGCTGTCACTCCGCCTGCAATAGACTCAAATGCCTCGCCCGCAGAGCTAGTGCTGACCTTC
GATAATAGTATCTCAGGTTTATCTAAGGATCGTTTACCTATTAACCAGGTCGGGGTGACAGACATCACCACTGAGCAACA
AGATACTCACCTTAAAGTCATCTTAGGTATGTCCAAAGTGAAACCTTACCAAGGTTCTGTCATGGGCAATTCATATCGAC
TCACAATTAACGATGAAGTGGCGGGTACTCAAGCCCAAGCTGAAAACCCTTTCGTTAATAGCATTAAAAATATCGATTTC
CGTCGTAATGATAATGGTGGCGGTGAGTTATTGGTCTATCTAAATAATCGCTCGGTTGCGGCTAATGTCGAGCAAGTGGG
CGCTAAGCTCGAAGTGAAGTTATATAACACAGATATTAATAACGATCTTCTGTATGTTATGGATGTGAAAGACTTCTCCA
CACCGGTAAAAAGTTTCGAGACCTTTAAAGAAGACTTAACAACGCGCATATTAGTTGATATCGCTGGCGAGTATGAATTC
ACTTACAAACAAGAAGATAACCTCTTTAGACTCTCAATGAATAAAGTCGAGAGAGCCGCCGCCAAGAAAGATGTTAAAAA
GTACAATGGTCGAACTTTATCGCTTAACTTCCAAAATATCCCAGTGCGTACTGTGTTGCAGATCATCGCCGACTATAACA
ACTTTAACTTAGTCACCAGCGATACTGTGGAAGGCAATATCACCTTAAGATTGGACGATGTGCCTTGGGATCAAGCTTTA
GAATTAATTCTGCAAACCAAAGGATTAGATAAGCGTATCGAAGGCAACATCTTAATGGTGGCGCCGAGCGAAGAACTGGC
AATTCGTGAAAGCCAAAACCTTAAAAACAAACAAGAAGTTAAAGAGTTAGCACCGCTCTATTCTGAGTACTTGCAAATTA
ACTACGCTAAAGCGGTCGATATTGCTGAGTTATTGAAAAGTGCTGACTCGAGCTTACTTTCACCACGCGGTTCAGTCGCG
GTCGATGAACGCACTAACACAGTGTTAGTGAAAGATACGGCTGAAACGATTGAGAACATTCACCGTTTAGTCGAAGTGCT
CGATATCCCCATCCGCCAAGTGTTGATCGAGTCACGCATGGTGACAGTGAAAGATGATGTCTCCGAAGACTTAGGTATTC
GTTGGGGCGTCACAGACCAGCAAGGTAGCAAGGGAACCTCTGGCACATTAGAAGGTGCACAGAGTATTGCCAATGGGATA
ATTCCTACTGCAGATCAGCGTTTGAATGTTAACTTGCCCTCGGCGGCCTCCAATCCAGCGAGTATTGCCTTTCATGTCGC
CAAATTGGCGGACGGTACCATTCTTGATTTGGAATTAAGTGCGTTAGAGCAAGAAAATAAAGGTGAGATCATCGCTAGCC
CTCGTATTACCACCTCTAACCAAAAGGCGGCTTATATTGAGCAAGGTGTCGAGATCCCTTATGTGCAGTCTACTTCGAGT
GGTGCAACGTCAGTCACGTTTAAGAAGGCGGTGTTGTCTCTACGGGTTACACCCCAAATTACGCCTGATAACCGAGTCAT
TTTAGATTTAGAAATCACTCAAGATTCTCAGGGTAAAACCGTTGATACTCCAACGGGTCCAGCAGTCGCCATCGATACTC
AACGCATCGGCACCCAAGTGCTCGTTAATAACGGTGAAACTATAGTGCTTGGCGGTATTTATCAGCAAAATCTGATCAGC
CGTGTGAGTAAAGTACCAATTCTAGGTGACATTCCTCTGGTTGGTTTCCTGTTTAGGAACACAACAGACAAAAATGAGCG
TCAAGAGCTACTTATTTTCGTCACCCCCAAAATAGTCGGTGAGAAGATCTAA

Upstream 100 bases:

>100_bases
CGAAGTAGTAGAATTAATTCCAGATGGTTCTGGTTGTTGGTCTGAAAGGACAAGCAATTTAGAACTTTCTGGAGAATAAC
GAGCGAAGGATGAGGAAATA

Downstream 100 bases:

>100_bases
GCACTTGCTATGTATCGACTAAAGCCAGCAGTTATTGCTGGCTTTATTATTACTGTTATACAATTCTTTGCATAAATAGC
GCACATGGCTTGCCATAGTA

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MKSSAAIKVPLLSSGLIKSVIGIALVFGILPSSFAANRLMDVKYHALVDHQLELELVFEEAVTPPAIDSNASPAELVLTF
DNSISGLSKDRLPINQVGVTDITTEQQDTHLKVILGMSKVKPYQGSVMGNSYRLTINDEVAGTQAQAENPFVNSIKNIDF
RRNDNGGGELLVYLNNRSVAANVEQVGAKLEVKLYNTDINNDLLYVMDVKDFSTPVKSFETFKEDLTTRILVDIAGEYEF
TYKQEDNLFRLSMNKVERAAAKKDVKKYNGRTLSLNFQNIPVRTVLQIIADYNNFNLVTSDTVEGNITLRLDDVPWDQAL
ELILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELAPLYSEYLQINYAKAVDIAELLKSADSSLLSPRGSVA
VDERTNTVLVKDTAETIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGSKGTSGTLEGAQSIANGI
IPTADQRLNVNLPSAASNPASIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYVQSTSS
GATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGPAVAIDTQRIGTQVLVNNGETIVLGGIYQQNLIS
RVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVGEKI

Sequences:

>Translated_683_residues
MKSSAAIKVPLLSSGLIKSVIGIALVFGILPSSFAANRLMDVKYHALVDHQLELELVFEEAVTPPAIDSNASPAELVLTF
DNSISGLSKDRLPINQVGVTDITTEQQDTHLKVILGMSKVKPYQGSVMGNSYRLTINDEVAGTQAQAENPFVNSIKNIDF
RRNDNGGGELLVYLNNRSVAANVEQVGAKLEVKLYNTDINNDLLYVMDVKDFSTPVKSFETFKEDLTTRILVDIAGEYEF
TYKQEDNLFRLSMNKVERAAAKKDVKKYNGRTLSLNFQNIPVRTVLQIIADYNNFNLVTSDTVEGNITLRLDDVPWDQAL
ELILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELAPLYSEYLQINYAKAVDIAELLKSADSSLLSPRGSVA
VDERTNTVLVKDTAETIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGSKGTSGTLEGAQSIANGI
IPTADQRLNVNLPSAASNPASIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYVQSTSS
GATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGPAVAIDTQRIGTQVLVNNGETIVLGGIYQQNLIS
RVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVGEKI
>Mature_683_residues
MKSSAAIKVPLLSSGLIKSVIGIALVFGILPSSFAANRLMDVKYHALVDHQLELELVFEEAVTPPAIDSNASPAELVLTF
DNSISGLSKDRLPINQVGVTDITTEQQDTHLKVILGMSKVKPYQGSVMGNSYRLTINDEVAGTQAQAENPFVNSIKNIDF
RRNDNGGGELLVYLNNRSVAANVEQVGAKLEVKLYNTDINNDLLYVMDVKDFSTPVKSFETFKEDLTTRILVDIAGEYEF
TYKQEDNLFRLSMNKVERAAAKKDVKKYNGRTLSLNFQNIPVRTVLQIIADYNNFNLVTSDTVEGNITLRLDDVPWDQAL
ELILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELAPLYSEYLQINYAKAVDIAELLKSADSSLLSPRGSVA
VDERTNTVLVKDTAETIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGSKGTSGTLEGAQSIANGI
IPTADQRLNVNLPSAASNPASIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYVQSTSS
GATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGPAVAIDTQRIGTQVLVNNGETIVLGGIYQQNLIS
RVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVGEKI

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=421, Percent_Identity=37.7672209026128, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI87082242, Length=373, Percent_Identity=30.8310991957105, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 74902; Mature: 74902

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSAAIKVPLLSSGLIKSVIGIALVFGILPSSFAANRLMDVKYHALVDHQLELELVFEE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHEECEEEEEEECCCEEEEEEEEC
AVTPPAIDSNASPAELVLTFDNSISGLSKDRLPINQVGVTDITTEQQDTHLKVILGMSKV
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEHHHC
KPYQGSVMGNSYRLTINDEVAGTQAQAENPFVNSIKNIDFRRNDNGGGELLVYLNNRSVA
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCEEEEEECCCCEE
ANVEQVGAKLEVKLYNTDINNDLLYVMDVKDFSTPVKSFETFKEDLTTRILVDIAGEYEF
CCHHHCCCEEEEEEEECCCCCCEEEEEECCHHCCHHHHHHHHHHHHHEEEEEEECCCEEE
TYKQEDNLFRLSMNKVERAAAKKDVKKYNGRTLSLNFQNIPVRTVLQIIADYNNFNLVTS
EEECCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEC
DTVEGNITLRLDDVPWDQALELILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEV
CCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHEEECCCCCCCHHHH
KELAPLYSEYLQINYAKAVDIAELLKSADSSLLSPRGSVAVDERTNTVLVKDTAETIENI
HHHHHHHHHHHEEEHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEEECHHHHHHHH
HRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGSKGTSGTLEGAQSIANGI
HHHHHHHHCHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCC
IPTADQRLNVNLPSAASNPASIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTSN
CCCCCCEEEEECCCCCCCCCCEEEEEEHHCCCEEEEEEHHHHCCCCCCCEEECCEEECCC
QKAAYIEQGVEIPYVQSTSSGATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKT
CCHHHHHCCCCCCEEECCCCCCCEEEEEEEEEEEEECCEECCCCEEEEEEEECCCCCCCE
VDTPTGPAVAIDTQRIGTQVLVNNGETIVLGGIYQQNLISRVSKVPILGDIPLVGFLFRN
ECCCCCCEEEEEHHHCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCEECCCHHHHEECC
TTDKNERQELLIFVTPKIVGEKI
CCCCCCCCEEEEEECCHHCCCCC
>Mature Secondary Structure
MKSSAAIKVPLLSSGLIKSVIGIALVFGILPSSFAANRLMDVKYHALVDHQLELELVFEE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHEECEEEEEEECCCEEEEEEEEC
AVTPPAIDSNASPAELVLTFDNSISGLSKDRLPINQVGVTDITTEQQDTHLKVILGMSKV
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEHHHC
KPYQGSVMGNSYRLTINDEVAGTQAQAENPFVNSIKNIDFRRNDNGGGELLVYLNNRSVA
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCEEEEEECCCCEE
ANVEQVGAKLEVKLYNTDINNDLLYVMDVKDFSTPVKSFETFKEDLTTRILVDIAGEYEF
CCHHHCCCEEEEEEEECCCCCCEEEEEECCHHCCHHHHHHHHHHHHHEEEEEEECCCEEE
TYKQEDNLFRLSMNKVERAAAKKDVKKYNGRTLSLNFQNIPVRTVLQIIADYNNFNLVTS
EEECCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEC
DTVEGNITLRLDDVPWDQALELILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEV
CCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHEEECCCCCCCHHHH
KELAPLYSEYLQINYAKAVDIAELLKSADSSLLSPRGSVAVDERTNTVLVKDTAETIENI
HHHHHHHHHHHEEEHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCCEEEEECHHHHHHHH
HRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGSKGTSGTLEGAQSIANGI
HHHHHHHHCHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCC
IPTADQRLNVNLPSAASNPASIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTSN
CCCCCCEEEEECCCCCCCCCCEEEEEEHHCCCEEEEEEHHHHCCCCCCCEEECCEEECCC
QKAAYIEQGVEIPYVQSTSSGATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKT
CCHHHHHCCCCCCEEECCCCCCCEEEEEEEEEEEEECCEECCCCEEEEEEEECCCCCCCE
VDTPTGPAVAIDTQRIGTQVLVNNGETIVLGGIYQQNLISRVSKVPILGDIPLVGFLFRN
ECCCCCCEEEEEHHHCCEEEEEECCCEEEECCHHHHHHHHHHHCCCCEECCCHHHHEECC
TTDKNERQELLIFVTPKIVGEKI
CCCCCCCCEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]