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The map label for this gene is trpS [H]

Identifier: 126176290

GI number: 126176290

Start: 4814003

End: 4815001

Strand: Reverse

Name: trpS [H]

Synonym: Sbal_4105

Alternate gene names: 126176290

Gene position: 4815001-4814003 (Counterclockwise)

Preceding gene: 126176291

Following gene: 126176288

Centisome position: 93.91

GC content: 49.65

Gene sequence:

>999_bases
ATGACCAAACCCATAGTACTCAGCGGTGCACAGCCGTCCGGCGAATTAACCATAGGTAACTACATGGGTGCATTGCGTCA
ATGGGTTGCGATGCAAGATAGCCACGACTGCCTCTATTGTGTGGTCGACTTGCATGCCATTACCGTGCGTCAAGATCCTA
AAGCGTTGCGCGAAGCCTGTTTAGACACCTTAGCCCTGTATTTGGCCTGTGGCGTCGATCCTAAAAAGAGCACAGTGTTT
ATCCAGTCACAAGTGCCACAACACACGCAATTGGGTTGGGCATTAAACTGCTACACCCAAATGGGCGAGTTGAGTCGTAT
GACGCAGTTTAAAGATAAGTCACAAAAGCACGCTAACAACATCAACGTGGGTCTGTTTGGTTACCCAGTGCTGATGGCGG
CGGATATTCTGATTTATCAAGCGAACGAAATCCCAGTTGGTCAAGATCAGAAGCAACACCTTGAGTTAACTCGTGATATC
GCGACTCGCTTCAACAATGCCTACGGTGATACTTTCACCATTCCTGAGCCATTTATTCCTGAACATGGCGCGAAAGTGAT
GTCGTTGCAGGAGCCGCTGAAGAAGATGTCTAAGTCAGACGAGAACCGTAACAACGTCATCGGCCTGCTAGAAGATCCAA
AAGCCGTGCTGAAGAAGCTGAAAAAAGCTATGACAGACAGTGATGAGCCGCCAGTCGTGCGTTTCGATATGGAGAATAAG
CCAGGCGTTTCGAACCTGCTGAGTTTAATGTCGGGTGTGACGGGACAAAGCATCGCAAGCCTAGAAGCCGAGTTTGAAGG
CAAGATGTATGGCCATTTGAAAGGGGCAGCAGGCGAAGCGGTTGTGAGCATGTTAGAGCCGCTGCAAGAGCGTTACCGCA
CGATTCGTGCCGACCGTGCTTACTTAGACCAAGTGATGAAAGCTGGCGCTGAAAGTGCGCAGGCGCGCGCCGAAGTGACA
TTGAAGAAAGTGTACGAGAAGATTGGTTTGTTAGTGTAA

Upstream 100 bases:

>100_bases
ATTTTGAACTGGGTAAAACCTACTAAGTAATGCGTGTTTACCCGTTTTTTAGTCGATTTTTTATAGTCTTTTTATATATA
GATAGTGGAGCAATGACGTA

Downstream 100 bases:

>100_bases
TCAATCGATATCGATAAATTAAGCCGACGTCAGCGTCGGCTTTTTTGTGTCTGTCTGTTCACCTTAGGCTTGTGATTTTA
GCCAAGAGGAGAAGGCGGCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVF
IQSQVPQHTQLGWALNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANEIPVGQDQKQHLELTRDI
ATRFNNAYGDTFTIPEPFIPEHGAKVMSLQEPLKKMSKSDENRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDMENK
PGVSNLLSLMSGVTGQSIASLEAEFEGKMYGHLKGAAGEAVVSMLEPLQERYRTIRADRAYLDQVMKAGAESAQARAEVT
LKKVYEKIGLLV

Sequences:

>Translated_332_residues
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVF
IQSQVPQHTQLGWALNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANEIPVGQDQKQHLELTRDI
ATRFNNAYGDTFTIPEPFIPEHGAKVMSLQEPLKKMSKSDENRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDMENK
PGVSNLLSLMSGVTGQSIASLEAEFEGKMYGHLKGAAGEAVVSMLEPLQERYRTIRADRAYLDQVMKAGAESAQARAEVT
LKKVYEKIGLLV
>Mature_331_residues
TKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREACLDTLALYLACGVDPKKSTVFI
QSQVPQHTQLGWALNCYTQMGELSRMTQFKDKSQKHANNINVGLFGYPVLMAADILIYQANEIPVGQDQKQHLELTRDIA
TRFNNAYGDTFTIPEPFIPEHGAKVMSLQEPLKKMSKSDENRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDMENKP
GVSNLLSLMSGVTGQSIASLEAEFEGKMYGHLKGAAGEAVVSMLEPLQERYRTIRADRAYLDQVMKAGAESAQARAEVTL
KKVYEKIGLLV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=39.8791540785499, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=50.2793296089386, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=73.1117824773414, Blast_Score=523, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.9281437125749, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.9281437125749, Blast_Score=197, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=38.8405797101449, Blast_Score=229, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=40.1215805471125, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36775; Mature: 36644

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREAC
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCHHHHHHHH
LDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWALNCYTQMGELSRMTQFKDKSQKHANN
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INVGLFGYPVLMAADILIYQANEIPVGQDQKQHLELTRDIATRFNNAYGDTFTIPEPFIP
CCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EHGAKVMSLQEPLKKMSKSDENRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDMENK
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
PGVSNLLSLMSGVTGQSIASLEAEFEGKMYGHLKGAAGEAVVSMLEPLQERYRTIRADRA
CCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
YLDQVMKAGAESAQARAEVTLKKVYEKIGLLV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKPIVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPKALREAC
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCHHHHHHHH
LDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWALNCYTQMGELSRMTQFKDKSQKHANN
HHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
INVGLFGYPVLMAADILIYQANEIPVGQDQKQHLELTRDIATRFNNAYGDTFTIPEPFIP
CCEEHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EHGAKVMSLQEPLKKMSKSDENRNNVIGLLEDPKAVLKKLKKAMTDSDEPPVVRFDMENK
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
PGVSNLLSLMSGVTGQSIASLEAEFEGKMYGHLKGAAGEAVVSMLEPLQERYRTIRADRA
CCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
YLDQVMKAGAESAQARAEVTLKKVYEKIGLLV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]