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The map label for this gene is dsbD [H]

Identifier: 126176261

GI number: 126176261

Start: 4781354

End: 4783414

Strand: Direct

Name: dsbD [H]

Synonym: Sbal_4075

Alternate gene names: 126176261

Gene position: 4781354-4783414 (Clockwise)

Preceding gene: 126176260

Following gene: 126176269

Centisome position: 93.25

GC content: 45.22

Gene sequence:

>2061_bases
ATGAAACGTTTAGCTCAGTTTATAACAGGATTTATTATCCTAATATGTTCGTTGCAAGTTATGGCCAATGAGCTAAGTCA
GTCTCAGCGCCTAATTTCTATTTCCATGATGATGGAGTCTGACAAGCCTGCAGCTGGAACCCACGAGCTCGCTATCACCA
TGACACCTCAAAAAGGCTGGCATGGTTATTGGCAAAATCCCGGTGATGCAGGCTTTCCAACGCGGTTTGATTGGCAGTTG
CCCGAAGACGTGACAATAGGAGAGGTGCAATATCCGGCACCGAGTCAGCTGGTGACCAGTGATATCATGAATTACATTTA
TCACGGCGAATATACCTTGCTTGCGCCTATCACTATTGATAGCAGCATTGCAGTTGGTACTTCGTTGCCCATCAAGCTCG
ATATCAGCTATCTAGTATGTAATCCAACAACCTGCTTGCCAGAACAACAGACAATCGAGCAAGACTTCATAGTCGGGGAT
GGCAAGGTTGAGCAGAATCATCAGCGGCAATTTAGCCAATGGCGTCAGATGCTACCTAGACCATTGGATGCTAAGGGGCA
GTTTGCAGTCGAAAACAATACTCTGACGCTGTCTTTACCGCTACCCGGTTCAGTCGACAGCCGTAATGCCCATATCTATC
CCATCATCAATAATACCCTAGTAAACAATGCACAGCAGATCCTGAACCATGAAGGCGATGTGCTGAGTATGCAAACGCAA
GTGGGTGATGAATTAGCTGATTTATTTCAAGGAGTTTTAGTATTAGAAAATGGTACCGCATTACGCTTTGATGCCCATAA
AACTGACCATGTCGCGTTTATTGTACCGCCGATAAATGAAGATAATACCAGCAATCAAAACATCTGGTTAATTGGCATCA
CGGCTTTTGTGGGCGCAATTCTAGGCGGCTTACTACTTAACATCATGCCCTGTGTATTTCCTATCCTGAGCTTAAAGATT
TTGAGTCTGTCACATCAAGGCTCGGAAAAAGCGGCGAGGATGGGCTCAGTTGCTTATACCTTAGGTGCGGTGTTGGTCTG
CATTTGCTTAGGTGGCGCTATCTTAGGCCTTAGGGCCTTGGGGCATCAAGTCGGCTGGGCATTCCAGTTGCAAAGTCCTG
CTGTAATTGCCGCATTGATCCTATTAATGAGCGCGATTGGGTTTAATTTGGCGGGCTTGTTCGAAATAGGGACATTAACC
TCAGGTTCTAAATTGCAAGATCAAAAAGGCCCCATGGGAGATTTCTGGACTGGGGTATTAGCGGCATTTATTGCAACGCC
TTGTACCGGGCCCTTTATGGCGACAGCTTTAGGTGCCGCCTTAGTATTACCAACGACGGTGGCATTGGTAATTTTTGCTG
GCTTAGGTTTTGGCATGGCATTACCGTTTCTATTGGTGGGTTTTATTCCGGCATTACGTACTCGTTTACCTAAGCCAGGG
GCTTGGATGGTCACCGCAAGGCGGATCCTTTCTTTGCCTATGTTTATTACCGTGTTAGGACTAGTGTGGATTTTGATGCG
TCAATCAAATGATAATTATGTCTTGTCTGTACTTGCAGCCACCATGTTATCTACCTTTGGTCTATGGCTTACTGGTTTGT
GGCAACACTCGCAACATAAAGGCCAGTGGTGGCCTAGCCTCTTATTGACGTTACTTCCTCTGTTGGCACTCCTTTATTGG
GTTCCACAGGCTGAATCCCATGTACAGGGTGAACAAAAAGAGGTGGCGGAAGCGCTTGTCTTTAGCCAAGAACAACTCAA
TATCTTAGGCGCGCAGCAAGATGTGTTTGTGTATTTTACGGCCGACTGGTGTTTAACCTGCAAGGTAAATGAGAAAACAT
CGATTGAGCGCCAAGAAGTCAAAGCAGCGTTTAAACAACATAATGTCGCGACTATGATTGGCGACTGGACAAACGGAGAT
AATCAGATCACTGAGTTTTTATCACAACATGGGCGTTCTGGAGTACCTTTGTATTTGTGGTATAAAAAAGGCGTAAACAA
ACCGATTGTTCTACCTCAAATATTGTCTCAAACAATATTAATTGAACAGGCCAAAGGATAA

Upstream 100 bases:

>100_bases
TTATCCTAAAATCCTCGATTCAAGATGATGATTTTGATGCCGTTTTACACACGATTTCAGCATTAAAATAACCCCTTCAT
CTTGATAATAAAGGCGTGAC

Downstream 100 bases:

>100_bases
AAGTTTAAATACGACACTGTAATGTCACATTTTAAGCATTAATTTCACCATCTGCACTTAGTGTTGGCTTTGCTGAATAA
ATCCTAGCATTAATCAACTT

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MKRLAQFITGFIILICSLQVMANELSQSQRLISISMMMESDKPAAGTHELAITMTPQKGWHGYWQNPGDAGFPTRFDWQL
PEDVTIGEVQYPAPSQLVTSDIMNYIYHGEYTLLAPITIDSSIAVGTSLPIKLDISYLVCNPTTCLPEQQTIEQDFIVGD
GKVEQNHQRQFSQWRQMLPRPLDAKGQFAVENNTLTLSLPLPGSVDSRNAHIYPIINNTLVNNAQQILNHEGDVLSMQTQ
VGDELADLFQGVLVLENGTALRFDAHKTDHVAFIVPPINEDNTSNQNIWLIGITAFVGAILGGLLLNIMPCVFPILSLKI
LSLSHQGSEKAARMGSVAYTLGAVLVCICLGGAILGLRALGHQVGWAFQLQSPAVIAALILLMSAIGFNLAGLFEIGTLT
SGSKLQDQKGPMGDFWTGVLAAFIATPCTGPFMATALGAALVLPTTVALVIFAGLGFGMALPFLLVGFIPALRTRLPKPG
AWMVTARRILSLPMFITVLGLVWILMRQSNDNYVLSVLAATMLSTFGLWLTGLWQHSQHKGQWWPSLLLTLLPLLALLYW
VPQAESHVQGEQKEVAEALVFSQEQLNILGAQQDVFVYFTADWCLTCKVNEKTSIERQEVKAAFKQHNVATMIGDWTNGD
NQITEFLSQHGRSGVPLYLWYKKGVNKPIVLPQILSQTILIEQAKG

Sequences:

>Translated_686_residues
MKRLAQFITGFIILICSLQVMANELSQSQRLISISMMMESDKPAAGTHELAITMTPQKGWHGYWQNPGDAGFPTRFDWQL
PEDVTIGEVQYPAPSQLVTSDIMNYIYHGEYTLLAPITIDSSIAVGTSLPIKLDISYLVCNPTTCLPEQQTIEQDFIVGD
GKVEQNHQRQFSQWRQMLPRPLDAKGQFAVENNTLTLSLPLPGSVDSRNAHIYPIINNTLVNNAQQILNHEGDVLSMQTQ
VGDELADLFQGVLVLENGTALRFDAHKTDHVAFIVPPINEDNTSNQNIWLIGITAFVGAILGGLLLNIMPCVFPILSLKI
LSLSHQGSEKAARMGSVAYTLGAVLVCICLGGAILGLRALGHQVGWAFQLQSPAVIAALILLMSAIGFNLAGLFEIGTLT
SGSKLQDQKGPMGDFWTGVLAAFIATPCTGPFMATALGAALVLPTTVALVIFAGLGFGMALPFLLVGFIPALRTRLPKPG
AWMVTARRILSLPMFITVLGLVWILMRQSNDNYVLSVLAATMLSTFGLWLTGLWQHSQHKGQWWPSLLLTLLPLLALLYW
VPQAESHVQGEQKEVAEALVFSQEQLNILGAQQDVFVYFTADWCLTCKVNEKTSIERQEVKAAFKQHNVATMIGDWTNGD
NQITEFLSQHGRSGVPLYLWYKKGVNKPIVLPQILSQTILIEQAKG
>Mature_686_residues
MKRLAQFITGFIILICSLQVMANELSQSQRLISISMMMESDKPAAGTHELAITMTPQKGWHGYWQNPGDAGFPTRFDWQL
PEDVTIGEVQYPAPSQLVTSDIMNYIYHGEYTLLAPITIDSSIAVGTSLPIKLDISYLVCNPTTCLPEQQTIEQDFIVGD
GKVEQNHQRQFSQWRQMLPRPLDAKGQFAVENNTLTLSLPLPGSVDSRNAHIYPIINNTLVNNAQQILNHEGDVLSMQTQ
VGDELADLFQGVLVLENGTALRFDAHKTDHVAFIVPPINEDNTSNQNIWLIGITAFVGAILGGLLLNIMPCVFPILSLKI
LSLSHQGSEKAARMGSVAYTLGAVLVCICLGGAILGLRALGHQVGWAFQLQSPAVIAALILLMSAIGFNLAGLFEIGTLT
SGSKLQDQKGPMGDFWTGVLAAFIATPCTGPFMATALGAALVLPTTVALVIFAGLGFGMALPFLLVGFIPALRTRLPKPG
AWMVTARRILSLPMFITVLGLVWILMRQSNDNYVLSVLAATMLSTFGLWLTGLWQHSQHKGQWWPSLLLTLLPLLALLYW
VPQAESHVQGEQKEVAEALVFSQEQLNILGAQQDVFVYFTADWCLTCKVNEKTSIERQEVKAAFKQHNVATMIGDWTNGD
NQITEFLSQHGRSGVPLYLWYKKGVNKPIVLPQILSQTILIEQAKG

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=401, Percent_Identity=26.1845386533666, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 75211; Mature: 75211

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLAQFITGFIILICSLQVMANELSQSQRLISISMMMESDKPAAGTHELAITMTPQKGW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCC
HGYWQNPGDAGFPTRFDWQLPEDVTIGEVQYPAPSQLVTSDIMNYIYHGEYTLLAPITID
CCCCCCCCCCCCCCCCCCCCCCCCEECCEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEC
SSIAVGTSLPIKLDISYLVCNPTTCLPEQQTIEQDFIVGDGKVEQNHQRQFSQWRQMLPR
CCEEECCCCCEEEEEEEEEECCCCCCCCHHHCCHHEEECCCCCCHHHHHHHHHHHHHCCC
PLDAKGQFAVENNTLTLSLPLPGSVDSRNAHIYPIINNTLVNNAQQILNHEGDVLSMQTQ
CCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEHHH
VGDELADLFQGVLVLENGTALRFDAHKTDHVAFIVPPINEDNTSNQNIWLIGITAFVGAI
HHHHHHHHHCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEHHHHHHHH
LGGLLLNIMPCVFPILSLKILSLSHQGSEKAARMGSVAYTLGAVLVCICLGGAILGLRAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHQVGWAFQLQSPAVIAALILLMSAIGFNLAGLFEIGTLTSGSKLQDQKGPMGDFWTGVL
HHHHCEEEEECCCHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHH
AAFIATPCTGPFMATALGAALVLPTTVALVIFAGLGFGMALPFLLVGFIPALRTRLPKPG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AWMVTARRILSLPMFITVLGLVWILMRQSNDNYVLSVLAATMLSTFGLWLTGLWQHSQHK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GQWWPSLLLTLLPLLALLYWVPQAESHVQGEQKEVAEALVFSQEQLNILGAQQDVFVYFT
CCHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
ADWCLTCKVNEKTSIERQEVKAAFKQHNVATMIGDWTNGDNQITEFLSQHGRSGVPLYLW
ECEEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEE
YKKGVNKPIVLPQILSQTILIEQAKG
EECCCCCCEEHHHHHHHHHHEEECCC
>Mature Secondary Structure
MKRLAQFITGFIILICSLQVMANELSQSQRLISISMMMESDKPAAGTHELAITMTPQKGW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCC
HGYWQNPGDAGFPTRFDWQLPEDVTIGEVQYPAPSQLVTSDIMNYIYHGEYTLLAPITID
CCCCCCCCCCCCCCCCCCCCCCCCEECCEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEC
SSIAVGTSLPIKLDISYLVCNPTTCLPEQQTIEQDFIVGDGKVEQNHQRQFSQWRQMLPR
CCEEECCCCCEEEEEEEEEECCCCCCCCHHHCCHHEEECCCCCCHHHHHHHHHHHHHCCC
PLDAKGQFAVENNTLTLSLPLPGSVDSRNAHIYPIINNTLVNNAQQILNHEGDVLSMQTQ
CCCCCCCEEEECCEEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEHHH
VGDELADLFQGVLVLENGTALRFDAHKTDHVAFIVPPINEDNTSNQNIWLIGITAFVGAI
HHHHHHHHHCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEEHHHHHHHH
LGGLLLNIMPCVFPILSLKILSLSHQGSEKAARMGSVAYTLGAVLVCICLGGAILGLRAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHQVGWAFQLQSPAVIAALILLMSAIGFNLAGLFEIGTLTSGSKLQDQKGPMGDFWTGVL
HHHHCEEEEECCCHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCHHHHHHH
AAFIATPCTGPFMATALGAALVLPTTVALVIFAGLGFGMALPFLLVGFIPALRTRLPKPG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AWMVTARRILSLPMFITVLGLVWILMRQSNDNYVLSVLAATMLSTFGLWLTGLWQHSQHK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GQWWPSLLLTLLPLLALLYWVPQAESHVQGEQKEVAEALVFSQEQLNILGAQQDVFVYFT
CCHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
ADWCLTCKVNEKTSIERQEVKAAFKQHNVATMIGDWTNGDNQITEFLSQHGRSGVPLYLW
ECEEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEE
YKKGVNKPIVLPQILSQTILIEQAKG
EECCCCCCEEHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]