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The map label for this gene is 126176209

Identifier: 126176209

GI number: 126176209

Start: 4721413

End: 4722777

Strand: Direct

Name: 126176209

Synonym: Sbal_4023

Alternate gene names: NA

Gene position: 4721413-4722777 (Clockwise)

Preceding gene: 126176208

Following gene: 126176211

Centisome position: 92.08

GC content: 50.48

Gene sequence:

>1365_bases
ATGCAATCGGCCAATACAAGTTCGACTAACCACTTCAGCTCACGCTTAGGTTTTATCATGGCGGCAGCCGGTAGCGCCGT
TGGTGTAGGTAACATCTGGGGATTCCCCACCCAAGCAGCCACCCATGGCGGCGGTGCCTTTTTACTGGTTTACCTGGTAC
TGATTTTCATCCTAGGCATTCCCATGTTAATGGCCGAACTCATGATAGGTCGCCACGGACAGACCAACCCCGCCGATGCC
ATGGGCAAACTCGGCTTCAACACCCTAACTCGCAGTTTAGGCAAGGCGATAGGTTTGATTTCCATCGTCACCGCGGGATT
AATCTATACCTTCTACAGCATTCTTTCTGGCTGGTTTGTCAGCTACGCCATCGCCCCGATTGCCACAGCTTTGGGCTCGA
ACGACACCGCAGCTTGGTTAGTGGATTTCTCGCTATCGCGCAATCTGGTGTTCACGCTGATCTTCAGCACACTCGTGTTT
CTGGTATTGCTGCAAGGCGTGCAAGAAGGCATAGAAAAATGGTCGAAACGCTTGATGCCGTTATTGTTGATCATGCTGAT
CGCGGGCGTGGCGTATATCTTCACCCTTAATGGCGCGAGCGAAGGCATTACCGCACTATTAACGCCTAACTTTGCCAAGG
CGCTGGCGCCAGATACCTTGATCAGCGCACTCGGACAAACCTTCTTCTCCCTCACCATAGGCACAGGTGCCATGATGGTT
TATGGCAGCTATTTGAGCCAAAAAGAGAATATCGCCAAGCTGACCGTCTGGGTTGCCTTTACCGATAGTGGCATCGCCTT
TCTCGCCGCTTTCTTGATTATCCCAGCCATGTATGTGGCCCAGCACAATGGCGTGGAGATTTTTAACGCCGAGGGTAAAT
TACTCGACTCAGATGCGCTGGTGTTTACTGTTTTACCCGCCTTATTTTCGACCTTAGGAGACACCGCCAACCTCATCATT
AGCGTGGTGTTCTTTATTCTGCTAATCATCGCCGGCCTAACTTCTGCCATTTCTATCGCCGAAGTCCCGACTAGCTATGT
GATGCAAAAATTCGGACTCAGCCGCCAGCGCGCAACCTTGATCATTGGCCTATTACTGACCTCATTATCCCTATTGCTGG
CGGTATTTTTTGAGACGTTATTTAGCTTCACTATTATGCTCACCACCCAAATCGCCCAGCCGCTGGTCGCCCTCGGTATC
GCGATTTACTTAGGTTGGATTTGGCGCCAAACACAATTACTCAAGGCAATTAGTGAACAAGATGGTGTTAATACCACAGG
ACTCTTCTGGCGCATTTGGCCAAGGTACGTGAAGTATGTGTGCCCAGTCCTGATCATCGCGATCGCTATCAGGCAATTTG
TGTAA

Upstream 100 bases:

>100_bases
AGAATATAAATTGCCGATTAACATCATTTTAACGCACTAAAATTGCGTTGAACTTCTTATTTATCCGCCTAAGATACGCC
TTCTTTTTACGGGAGGCACA

Downstream 100 bases:

>100_bases
GCCTTTAAAAAGCAAAAATCCCCGCTGAGTGCGGGGATTTTTTATTTAGCAATTGATGATCTAATTAACTTTTTTAAATA
ATCATCAAGGGCTTGCTGCC

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQSANTSSTNHFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGIPMLMAELMIGRHGQTNPADA
MGKLGFNTLTRSLGKAIGLISIVTAGLIYTFYSILSGWFVSYAIAPIATALGSNDTAAWLVDFSLSRNLVFTLIFSTLVF
LVLLQGVQEGIEKWSKRLMPLLLIMLIAGVAYIFTLNGASEGITALLTPNFAKALAPDTLISALGQTFFSLTIGTGAMMV
YGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLIIPAMYVAQHNGVEIFNAEGKLLDSDALVFTVLPALFSTLGDTANLII
SVVFFILLIIAGLTSAISIAEVPTSYVMQKFGLSRQRATLIIGLLLTSLSLLLAVFFETLFSFTIMLTTQIAQPLVALGI
AIYLGWIWRQTQLLKAISEQDGVNTTGLFWRIWPRYVKYVCPVLIIAIAIRQFV

Sequences:

>Translated_454_residues
MQSANTSSTNHFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGIPMLMAELMIGRHGQTNPADA
MGKLGFNTLTRSLGKAIGLISIVTAGLIYTFYSILSGWFVSYAIAPIATALGSNDTAAWLVDFSLSRNLVFTLIFSTLVF
LVLLQGVQEGIEKWSKRLMPLLLIMLIAGVAYIFTLNGASEGITALLTPNFAKALAPDTLISALGQTFFSLTIGTGAMMV
YGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLIIPAMYVAQHNGVEIFNAEGKLLDSDALVFTVLPALFSTLGDTANLII
SVVFFILLIIAGLTSAISIAEVPTSYVMQKFGLSRQRATLIIGLLLTSLSLLLAVFFETLFSFTIMLTTQIAQPLVALGI
AIYLGWIWRQTQLLKAISEQDGVNTTGLFWRIWPRYVKYVCPVLIIAIAIRQFV
>Mature_454_residues
MQSANTSSTNHFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGIPMLMAELMIGRHGQTNPADA
MGKLGFNTLTRSLGKAIGLISIVTAGLIYTFYSILSGWFVSYAIAPIATALGSNDTAAWLVDFSLSRNLVFTLIFSTLVF
LVLLQGVQEGIEKWSKRLMPLLLIMLIAGVAYIFTLNGASEGITALLTPNFAKALAPDTLISALGQTFFSLTIGTGAMMV
YGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLIIPAMYVAQHNGVEIFNAEGKLLDSDALVFTVLPALFSTLGDTANLII
SVVFFILLIIAGLTSAISIAEVPTSYVMQKFGLSRQRATLIIGLLLTSLSLLLAVFFETLFSFTIMLTTQIAQPLVALGI
AIYLGWIWRQTQLLKAISEQDGVNTTGLFWRIWPRYVKYVCPVLIIAIAIRQFV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=509, Percent_Identity=23.1827111984283, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4507043, Length=484, Percent_Identity=24.1735537190083, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI134304856, Length=333, Percent_Identity=27.3273273273273, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI188528618, Length=402, Percent_Identity=24.3781094527363, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI51468073, Length=294, Percent_Identity=27.2108843537415, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4507041, Length=508, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI289191351, Length=511, Percent_Identity=23.4833659491194, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4557046, Length=511, Percent_Identity=23.4833659491194, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI289191377, Length=511, Percent_Identity=23.4833659491194, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI58219014, Length=559, Percent_Identity=23.7924865831843, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI33354281, Length=298, Percent_Identity=26.510067114094, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI197276623, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI54607094, Length=335, Percent_Identity=25.9701492537313, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI7657587, Length=490, Percent_Identity=24.0816326530612, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI171184408, Length=493, Percent_Identity=23.5294117647059, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI171184406, Length=493, Percent_Identity=23.5294117647059, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI171184404, Length=493, Percent_Identity=23.5294117647059, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI92859670, Length=434, Percent_Identity=23.7327188940092, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI194018524, Length=311, Percent_Identity=25.08038585209, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI11181770, Length=295, Percent_Identity=25.4237288135593, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI21361693, Length=112, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI289191353, Length=306, Percent_Identity=26.4705882352941, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI12408638, Length=266, Percent_Identity=24.4360902255639, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI197276625, Length=161, Percent_Identity=27.3291925465839, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI300360519, Length=284, Percent_Identity=25.7042253521127, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=375, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71995588, Length=406, Percent_Identity=24.384236453202, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146584, Length=418, Percent_Identity=21.7703349282297, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555248, Length=217, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=122, Percent_Identity=28.6885245901639, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212642127, Length=106, Percent_Identity=31.1320754716981, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133952791, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI17136952, Length=388, Percent_Identity=25.2577319587629, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281364394, Length=388, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28574704, Length=388, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136950, Length=388, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28574702, Length=388, Percent_Identity=25, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24762620, Length=504, Percent_Identity=25, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655079, Length=305, Percent_Identity=27.8688524590164, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639516, Length=300, Percent_Identity=26, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639514, Length=300, Percent_Identity=26, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221329674, Length=301, Percent_Identity=26.578073089701, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654186, Length=354, Percent_Identity=27.9661016949153, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281365034, Length=477, Percent_Identity=23.0607966457023, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19921936, Length=500, Percent_Identity=23.4, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281364136, Length=516, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24661428, Length=313, Percent_Identity=27.1565495207668, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652942, Length=489, Percent_Identity=23.9263803680982, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45551088, Length=489, Percent_Identity=23.9263803680982, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363702, Length=497, Percent_Identity=23.3400402414487, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582567, Length=333, Percent_Identity=23.4234234234234, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45550877, Length=111, Percent_Identity=34.2342342342342, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551183, Length=111, Percent_Identity=34.2342342342342, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48934; Mature: 48934

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSANTSSTNHFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGI
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PMLMAELMIGRHGQTNPADAMGKLGFNTLTRSLGKAIGLISIVTAGLIYTFYSILSGWFV
HHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYAIAPIATALGSNDTAAWLVDFSLSRNLVFTLIFSTLVFLVLLQGVQEGIEKWSKRLMP
HHHHHHHHHHHCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIMLIAGVAYIFTLNGASEGITALLTPNFAKALAPDTLISALGQTFFSLTIGTGAMMV
HHHHHHHHHHHHHHEECCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH
YGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLIIPAMYVAQHNGVEIFNAEGKLLDSDAL
HHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCHH
VFTVLPALFSTLGDTANLIISVVFFILLIIAGLTSAISIAEVPTSYVMQKFGLSRQRATL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
IIGLLLTSLSLLLAVFFETLFSFTIMLTTQIAQPLVALGIAIYLGWIWRQTQLLKAISEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVNTTGLFWRIWPRYVKYVCPVLIIAIAIRQFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQSANTSSTNHFSSRLGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLVLIFILGI
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PMLMAELMIGRHGQTNPADAMGKLGFNTLTRSLGKAIGLISIVTAGLIYTFYSILSGWFV
HHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYAIAPIATALGSNDTAAWLVDFSLSRNLVFTLIFSTLVFLVLLQGVQEGIEKWSKRLMP
HHHHHHHHHHHCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLIMLIAGVAYIFTLNGASEGITALLTPNFAKALAPDTLISALGQTFFSLTIGTGAMMV
HHHHHHHHHHHHHHEECCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH
YGSYLSQKENIAKLTVWVAFTDSGIAFLAAFLIIPAMYVAQHNGVEIFNAEGKLLDSDAL
HHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEECCCHH
VFTVLPALFSTLGDTANLIISVVFFILLIIAGLTSAISIAEVPTSYVMQKFGLSRQRATL
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
IIGLLLTSLSLLLAVFFETLFSFTIMLTTQIAQPLVALGIAIYLGWIWRQTQLLKAISEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVNTTGLFWRIWPRYVKYVCPVLIIAIAIRQFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]