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The map label for this gene is ykoW [H]

Identifier: 126176197

GI number: 126176197

Start: 4706082

End: 4708001

Strand: Direct

Name: ykoW [H]

Synonym: Sbal_4010

Alternate gene names: 126176197

Gene position: 4706082-4708001 (Clockwise)

Preceding gene: 126176196

Following gene: 126176199

Centisome position: 91.78

GC content: 44.11

Gene sequence:

>1920_bases
ATGACACTGTTTAGACAGATTTATTCGCTGCTTTTTAGCCTATTTTTGCTCGTAGTTGCAAGCCTTGGCTATGTGCAATT
TACTGAGACTCAAAGCTTTTTAACCAAGCAAATGGAGTCAGATCTAAACAATGCCAGCACTTCACTTGGTCTAATGCTTA
CTCCAGCACTTCAAGCTGGCGATACCGCAGCGGCAGAAACCTTAGTGAATGTCATCTTTGAAGGTGGCTATTATCAAAAT
GTAAAGCTGACATGGATGGTGGATGGTAAGCAACAAGAGTGGAATAACCCTTTAAGAATTGAAGATGTACCTCAATGGTT
TATCAATTTAAATCTATTTAAAACCATCAAAAAACAAAGCACTATCACTTCTGGCTGGTTGCAACTCGCGCAACTTGAGA
TCACCGCTCATCCTGGGTTTGGTTACCATGAGCTGTGGCGAATCATGTCCAATACGATCATTGCCTTCTCTCTACTTTTC
CTCGTAGCCATTTTTACCGCAAGAATTGGTTTAACGTGGATATTGAAACCTCTACACACTTTGTCGGAACACGCGAAAAG
TATTGCGGCACGCCAATTTGGCCCAGGCATGGCATTACCTAAGACCACTGAATTGAAAGACTTAGTGACCGCATTTAACA
GTATGTCGGCGCAGTTAAAGCAAGTATTCCATTCCCTCGACGAAGAAGTCGGCGCGTTACGTAAGAAGAATCTTGTCGAT
CCTGCGTCAGGCCTGCCTAACCGCCAATATCTGGTAAGCCGTTTAAATGGTTGGTTGAGTGAACCTAGCAGCGGCGCGTT
ATTCCTCGCTAAACTCGACTGGCTCGAAGAAGTGCACAGCAAATATGGCTACCAAGTTCGAGATGAAACCATACGGATCT
TGGCAGAAAAGTTTCAGCTGCAGTTAAACGAAATAACACCGTCTGTTATAGGCCGCATTGCCGCCTATGAATTTGCATTT
TTAGTGACTGATGTTGAACACGATCAAATCAGCAAATATTTACAAACGCTTATCCGCACCATCAACCAAGAAATGTCGAA
GGCGGGCTGTAAGCCTAATGAAGACTTTGCGATTGGTATTGCGGAGCGTATTGGGCAAATGAATGTGTCGGATATTTTGG
CTCAAGCCGACAACGCCCTTCAAAAAGCGTTACAAGAAAATAAAACATTCCATTGGTTTGAAACCACAGAGCAGCAACTA
TTCACCCGTGAACAGTGGCGGGATAACCTTAGCCATGCCATCAGTAATAAGAAGTTTAAGTTTAGATGGCAGCCTATCCA
GTTTTGCGATGGGGATGGTATAGCGCAGCGGGAATTATATTGCCAATTAGAGCTCGGCGATCAACTCGCCCATGCAGGGC
AATTTATGCCTTATATCGAGCTCTTATCTCTCGGTGCCTTGCTCGATAAATGCTTAATTGAAACCGTCTACGAGCAAAAA
CTACTAGAGCGTAGCTATGAACCGCTCGCGATTAACTTAACCCACCAAAGCATTAACGATCCTCAGTTCCATGAGTGGCT
CAATCACTTCTTACGTAATGCTACATTTATTGAGCGGATCTGCTTCGAAATCCCTGAGGCGGGCGTTTATAGCGATCTTA
AGTCGTGTCAGCACTTATGTAACATTATTCGTGATAATGGCGCTAAGTTCGGCATTGACCACTTTGGCCGTCAGTTTGGC
TCTATGTCTTATCTACAGGAATTAAGACCGAGTTATGTGAAACTCGATCAATCCTTCGCCTACTATGATGAGACACACCA
TAATAGTGAGCTCTGCCGCGCGCTAATCAACGTAGCGAAAGGATTAGATATTCAAGTCATAGTGACGGGTATTCAAGAAA
AAGCTCAGCTAGAGCGCTTTAACGAGCTTAGAACTGATGCCTATCAGGGCTTTATCGCCCCTCCGGTGAGTCTTGATTAA

Upstream 100 bases:

>100_bases
CGGGTTCGTCTACACGGCTAGAAAAATGGAACGATCTTAACCATAGATTAGGTGTTGACCGCCTTAGACAACCAAAATTA
AAACTGGAGTAGCACCAAAA

Downstream 100 bases:

>100_bases
GCCGAATTAAGAAGTGATATTAAAAACAAAAAGCTCCGTAAGGAGCTTTTTACTTTTCTAACGACAGAATGCCTATATCG
ATACCGTTGCACATCTGTAT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MTLFRQIYSLLFSLFLLVVASLGYVQFTETQSFLTKQMESDLNNASTSLGLMLTPALQAGDTAAAETLVNVIFEGGYYQN
VKLTWMVDGKQQEWNNPLRIEDVPQWFINLNLFKTIKKQSTITSGWLQLAQLEITAHPGFGYHELWRIMSNTIIAFSLLF
LVAIFTARIGLTWILKPLHTLSEHAKSIAARQFGPGMALPKTTELKDLVTAFNSMSAQLKQVFHSLDEEVGALRKKNLVD
PASGLPNRQYLVSRLNGWLSEPSSGALFLAKLDWLEEVHSKYGYQVRDETIRILAEKFQLQLNEITPSVIGRIAAYEFAF
LVTDVEHDQISKYLQTLIRTINQEMSKAGCKPNEDFAIGIAERIGQMNVSDILAQADNALQKALQENKTFHWFETTEQQL
FTREQWRDNLSHAISNKKFKFRWQPIQFCDGDGIAQRELYCQLELGDQLAHAGQFMPYIELLSLGALLDKCLIETVYEQK
LLERSYEPLAINLTHQSINDPQFHEWLNHFLRNATFIERICFEIPEAGVYSDLKSCQHLCNIIRDNGAKFGIDHFGRQFG
SMSYLQELRPSYVKLDQSFAYYDETHHNSELCRALINVAKGLDIQVIVTGIQEKAQLERFNELRTDAYQGFIAPPVSLD

Sequences:

>Translated_639_residues
MTLFRQIYSLLFSLFLLVVASLGYVQFTETQSFLTKQMESDLNNASTSLGLMLTPALQAGDTAAAETLVNVIFEGGYYQN
VKLTWMVDGKQQEWNNPLRIEDVPQWFINLNLFKTIKKQSTITSGWLQLAQLEITAHPGFGYHELWRIMSNTIIAFSLLF
LVAIFTARIGLTWILKPLHTLSEHAKSIAARQFGPGMALPKTTELKDLVTAFNSMSAQLKQVFHSLDEEVGALRKKNLVD
PASGLPNRQYLVSRLNGWLSEPSSGALFLAKLDWLEEVHSKYGYQVRDETIRILAEKFQLQLNEITPSVIGRIAAYEFAF
LVTDVEHDQISKYLQTLIRTINQEMSKAGCKPNEDFAIGIAERIGQMNVSDILAQADNALQKALQENKTFHWFETTEQQL
FTREQWRDNLSHAISNKKFKFRWQPIQFCDGDGIAQRELYCQLELGDQLAHAGQFMPYIELLSLGALLDKCLIETVYEQK
LLERSYEPLAINLTHQSINDPQFHEWLNHFLRNATFIERICFEIPEAGVYSDLKSCQHLCNIIRDNGAKFGIDHFGRQFG
SMSYLQELRPSYVKLDQSFAYYDETHHNSELCRALINVAKGLDIQVIVTGIQEKAQLERFNELRTDAYQGFIAPPVSLD
>Mature_638_residues
TLFRQIYSLLFSLFLLVVASLGYVQFTETQSFLTKQMESDLNNASTSLGLMLTPALQAGDTAAAETLVNVIFEGGYYQNV
KLTWMVDGKQQEWNNPLRIEDVPQWFINLNLFKTIKKQSTITSGWLQLAQLEITAHPGFGYHELWRIMSNTIIAFSLLFL
VAIFTARIGLTWILKPLHTLSEHAKSIAARQFGPGMALPKTTELKDLVTAFNSMSAQLKQVFHSLDEEVGALRKKNLVDP
ASGLPNRQYLVSRLNGWLSEPSSGALFLAKLDWLEEVHSKYGYQVRDETIRILAEKFQLQLNEITPSVIGRIAAYEFAFL
VTDVEHDQISKYLQTLIRTINQEMSKAGCKPNEDFAIGIAERIGQMNVSDILAQADNALQKALQENKTFHWFETTEQQLF
TREQWRDNLSHAISNKKFKFRWQPIQFCDGDGIAQRELYCQLELGDQLAHAGQFMPYIELLSLGALLDKCLIETVYEQKL
LERSYEPLAINLTHQSINDPQFHEWLNHFLRNATFIERICFEIPEAGVYSDLKSCQHLCNIIRDNGAKFGIDHFGRQFGS
MSYLQELRPSYVKLDQSFAYYDETHHNSELCRALINVAKGLDIQVIVTGIQEKAQLERFNELRTDAYQGFIAPPVSLD

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=413, Percent_Identity=21.3075060532688, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72980; Mature: 72849

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFRQIYSLLFSLFLLVVASLGYVQFTETQSFLTKQMESDLNNASTSLGLMLTPALQAG
CCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
DTAAAETLVNVIFEGGYYQNVKLTWMVDGKQQEWNNPLRIEDVPQWFINLNLFKTIKKQS
CHHHHHHHHHHHHCCCEEECEEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
TITSGWLQLAQLEITAHPGFGYHELWRIMSNTIIAFSLLFLVAIFTARIGLTWILKPLHT
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEHAKSIAARQFGPGMALPKTTELKDLVTAFNSMSAQLKQVFHSLDEEVGALRKKNLVD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PASGLPNRQYLVSRLNGWLSEPSSGALFLAKLDWLEEVHSKYGYQVRDETIRILAEKFQL
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QLNEITPSVIGRIAAYEFAFLVTDVEHDQISKYLQTLIRTINQEMSKAGCKPNEDFAIGI
HHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEH
AERIGQMNVSDILAQADNALQKALQENKTFHWFETTEQQLFTREQWRDNLSHAISNKKFK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEE
FRWQPIQFCDGDGIAQRELYCQLELGDQLAHAGQFMPYIELLSLGALLDKCLIETVYEQK
EEECCCEEECCCCCCCHHHEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLERSYEPLAINLTHQSINDPQFHEWLNHFLRNATFIERICFEIPEAGVYSDLKSCQHLC
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NIIRDNGAKFGIDHFGRQFGSMSYLQELRPSYVKLDQSFAYYDETHHNSELCRALINVAK
HHHHCCCCEECHHHHHHHHCCHHHHHHHCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHC
GLDIQVIVTGIQEKAQLERFNELRTDAYQGFIAPPVSLD
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TLFRQIYSLLFSLFLLVVASLGYVQFTETQSFLTKQMESDLNNASTSLGLMLTPALQAG
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
DTAAAETLVNVIFEGGYYQNVKLTWMVDGKQQEWNNPLRIEDVPQWFINLNLFKTIKKQS
CHHHHHHHHHHHHCCCEEECEEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
TITSGWLQLAQLEITAHPGFGYHELWRIMSNTIIAFSLLFLVAIFTARIGLTWILKPLHT
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEHAKSIAARQFGPGMALPKTTELKDLVTAFNSMSAQLKQVFHSLDEEVGALRKKNLVD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PASGLPNRQYLVSRLNGWLSEPSSGALFLAKLDWLEEVHSKYGYQVRDETIRILAEKFQL
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QLNEITPSVIGRIAAYEFAFLVTDVEHDQISKYLQTLIRTINQEMSKAGCKPNEDFAIGI
HHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEH
AERIGQMNVSDILAQADNALQKALQENKTFHWFETTEQQLFTREQWRDNLSHAISNKKFK
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEE
FRWQPIQFCDGDGIAQRELYCQLELGDQLAHAGQFMPYIELLSLGALLDKCLIETVYEQK
EEECCCEEECCCCCCCHHHEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLERSYEPLAINLTHQSINDPQFHEWLNHFLRNATFIERICFEIPEAGVYSDLKSCQHLC
HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
NIIRDNGAKFGIDHFGRQFGSMSYLQELRPSYVKLDQSFAYYDETHHNSELCRALINVAK
HHHHCCCCEECHHHHHHHHCCHHHHHHHCHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHC
GLDIQVIVTGIQEKAQLERFNELRTDAYQGFIAPPVSLD
CCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]