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The map label for this gene is xerC [H]

Identifier: 126176181

GI number: 126176181

Start: 4681294

End: 4682214

Strand: Reverse

Name: xerC [H]

Synonym: Sbal_3993

Alternate gene names: 126176181

Gene position: 4682214-4681294 (Counterclockwise)

Preceding gene: 126176182

Following gene: 126176180

Centisome position: 91.32

GC content: 48.43

Gene sequence:

>921_bases
ATGAGTACGCAAACAGCCGAAGTGTCGGCGCTTAATACTCAATGGTTACAAACCTTTGAACGCTATCTGAGTACCGAGCG
GCAGTTGTCGGCCCATACAGTACGTAATTACCTTTACGAGCTTAATCGCGGAAGCGATCTCTTGCCTGACGGCGTGAATC
TACTCAATGTGAGTCGCGAGCATTGGCAGCAAGTGTTAGCCAAATTGCACCGCAAAGGCTTAAGCCCGCGATCGCTTTCT
CTGTGCTTATCTGCGGTAAAACAATGGGGTGAATTTTTGCTGCGCGAAGGTGTGATTGAGCTTAATCCTGCCAAAGGCTT
AAGTGCTCCCAAACAAGCCAAACCGCTGCCGAAGAATATCGATGTCGATGCCATCAGTCATTTGCTGGACATTGAAGGCA
CGGATCCCCTAAGCCTGCGGGATAAAGCCATGATGGAATTGTTTTATTCCAGTGGTTTACGTTTAGCAGAACTCGCCGCG
CTTAATTTATCCAGTGTGCAATACGATTTGAAAGAAGTGCGAGTCTTAGGTAAAGGCAATAAGGAACGTATCGTCCCTGT
CGGTCGTTTAGCGATTGCTGCTTTGCTGAATTGGCTCAATTGCCGAAAGCAGATCCCCTGTGAAGATAACGCCTTATTTG
TGACCGAAAAGGGCAAGCGACTCTCCCATCGTAGTATTCAGGCGCGGATGGCGAAATGGGGGCAAGAGCAGGCATTATCG
GTGCGCGTGCATCCACATAAACTACGCCATTCCTTTGCCACTCACATGTTAGAAGCGAGCGCCGATCTGCGGGCGGTGCA
AGAATTATTGGGCCATGCGAACCTAGCGACTACGCAAATTTATACCAGTTTGGATTTCCAACACTTAGCTAAGGTGTACG
ATAACGCCCATCCTAGAGCGAAAAAAACACAGGATAAATAA

Upstream 100 bases:

>100_bases
ACAACTGCGGCGTTTACTGGCGCACATGCTCGCTAAGCTGTAACGGCTGTTGAGCCATTGTGCTCGCCTAAGGCTTGGCA
AAACCCATGAGGAAACCGAT

Downstream 100 bases:

>100_bases
TGCGTTGCTATCTAAGACCTCAAAATATTCAAGCGATCAGTTTCGATCTCGACGATACCCTGTACGACAACCTACCGCAT
ATTTTAAATGCCGAAGCTGA

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSTQTAEVSALNTQWLQTFERYLSTERQLSAHTVRNYLYELNRGSDLLPDGVNLLNVSREHWQQVLAKLHRKGLSPRSLS
LCLSAVKQWGEFLLREGVIELNPAKGLSAPKQAKPLPKNIDVDAISHLLDIEGTDPLSLRDKAMMELFYSSGLRLAELAA
LNLSSVQYDLKEVRVLGKGNKERIVPVGRLAIAALLNWLNCRKQIPCEDNALFVTEKGKRLSHRSIQARMAKWGQEQALS
VRVHPHKLRHSFATHMLEASADLRAVQELLGHANLATTQIYTSLDFQHLAKVYDNAHPRAKKTQDK

Sequences:

>Translated_306_residues
MSTQTAEVSALNTQWLQTFERYLSTERQLSAHTVRNYLYELNRGSDLLPDGVNLLNVSREHWQQVLAKLHRKGLSPRSLS
LCLSAVKQWGEFLLREGVIELNPAKGLSAPKQAKPLPKNIDVDAISHLLDIEGTDPLSLRDKAMMELFYSSGLRLAELAA
LNLSSVQYDLKEVRVLGKGNKERIVPVGRLAIAALLNWLNCRKQIPCEDNALFVTEKGKRLSHRSIQARMAKWGQEQALS
VRVHPHKLRHSFATHMLEASADLRAVQELLGHANLATTQIYTSLDFQHLAKVYDNAHPRAKKTQDK
>Mature_305_residues
STQTAEVSALNTQWLQTFERYLSTERQLSAHTVRNYLYELNRGSDLLPDGVNLLNVSREHWQQVLAKLHRKGLSPRSLSL
CLSAVKQWGEFLLREGVIELNPAKGLSAPKQAKPLPKNIDVDAISHLLDIEGTDPLSLRDKAMMELFYSSGLRLAELAAL
NLSSVQYDLKEVRVLGKGNKERIVPVGRLAIAALLNWLNCRKQIPCEDNALFVTEKGKRLSHRSIQARMAKWGQEQALSV
RVHPHKLRHSFATHMLEASADLRAVQELLGHANLATTQIYTSLDFQHLAKVYDNAHPRAKKTQDK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=50.4983388704319, Blast_Score=293, Evalue=8e-81,
Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=35.0515463917526, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=29.4444444444444, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790768, Length=160, Percent_Identity=30, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34505; Mature: 34374

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQTAEVSALNTQWLQTFERYLSTERQLSAHTVRNYLYELNRGSDLLPDGVNLLNVSRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHH
HWQQVLAKLHRKGLSPRSLSLCLSAVKQWGEFLLREGVIELNPAKGLSAPKQAKPLPKNI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHCCCCCCCC
DVDAISHLLDIEGTDPLSLRDKAMMELFYSSGLRLAELAALNLSSVQYDLKEVRVLGKGN
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KERIVPVGRLAIAALLNWLNCRKQIPCEDNALFVTEKGKRLSHRSIQARMAKWGQEQALS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCEE
VRVHPHKLRHSFATHMLEASADLRAVQELLGHANLATTQIYTSLDFQHLAKVYDNAHPRA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
KKTQDK
CCCCCC
>Mature Secondary Structure 
STQTAEVSALNTQWLQTFERYLSTERQLSAHTVRNYLYELNRGSDLLPDGVNLLNVSRE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHH
HWQQVLAKLHRKGLSPRSLSLCLSAVKQWGEFLLREGVIELNPAKGLSAPKQAKPLPKNI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHCCCCCCCC
DVDAISHLLDIEGTDPLSLRDKAMMELFYSSGLRLAELAALNLSSVQYDLKEVRVLGKGN
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
KERIVPVGRLAIAALLNWLNCRKQIPCEDNALFVTEKGKRLSHRSIQARMAKWGQEQALS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHCEE
VRVHPHKLRHSFATHMLEASADLRAVQELLGHANLATTQIYTSLDFQHLAKVYDNAHPRA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCC
KKTQDK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA