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The map label for this gene is ttdR [H]

Identifier: 126176121

GI number: 126176121

Start: 4624708

End: 4625634

Strand: Reverse

Name: ttdR [H]

Synonym: Sbal_3931

Alternate gene names: 126176121

Gene position: 4625634-4624708 (Counterclockwise)

Preceding gene: 126176124

Following gene: 126176118

Centisome position: 90.21

GC content: 48.33

Gene sequence:

>927_bases
ATGTTGATTAATGATTTAGCTTTGTTCGTGCGGGTCGCCGATTGTGGCAATATTTCTGCCGCTGCGGCCGAGATGGATAT
CTCCGCCGCTTCTGCCAGTGCCGCAATAAAACGGCTTGAAAAACAGCTCGATACTAGCTTATTTATCCGCACAACTCGCA
GCTTACGTTTGACTGTGCAAGGTGAGCGTTATCTTATTCATTGTCGACGGGCTTTAAGCGATTTAGCGCTCGGCGAACAG
GCTATCGCCAGTGACAAAGGTAAGATCTCCGGCACCTTGAGTCTGTCTGTGTCTTCGGATTTTGGTCGTAATCTGTTTGT
GCCTTGGCTCGATGAGTTCTTGCTCGATTTCCCACAATTGCAAGTGCGCTTGCATCTTGGCGATAATATCAGCAGCTTTT
ATCACGATAAAATTGATGTCGCGGTGCGTTACGGCAAACCGCAGGACTCAAACCAAGTGGCATTTCCGCTCTGCAGTGTT
GATCGTGTCTTGTGCGCCTCACCTGAATATCTGGCCGAGTTTGGTGTGCCAGATTCATTAGAACAGCTGATAGAGCATAA
TTGCTTGTTTTATAAGTTAGATGAGCGAACCCACGATCAATGGCAATTTAGGCGCGACGGCCAAGAATATAAAGTGCGTG
TCACGGGCAACCGTAGTGCTAACGATGCGGAAATAGCTCGTCGCTGGGCTGTGGCAGGTAAAGGATTGGTATTTAAGTCG
AGTCTAGATCTGGCCGATGACTTAATTTCAGGGCGGTTAGTACGATTGTTGCCTGAGTATCAAGGTGAGCCAGTCGATTT
GTACCTAGTGTGCCCAGGACGCGAGCATGTAACGCCTGTTGTCTTGTTGCTGCGGGAAATGCTGCGGCAGCGCACACAGG
CTTTGAGTAAAAGCTTAGGTCAAATACTGGCAGTAAAAAAATCTTAG

Upstream 100 bases:

>100_bases
CTGTTTGAGTGTACTTGTATCGTGTTGCCATTGTGTGGAATATTAGCTAAGAGATAAACAGGGTAAAGTTTGTAATTTTT
TCAAAGGATTTTTGATAATC

Downstream 100 bases:

>100_bases
GATTTAAGAAACAAAAAAGCCGCATGATGCGGCTTTTTAGCGACTCGCGAAGATTAAGACTTAGCGCGTTTCATGGCGGT
AAAGAATTCTTCGTTAGTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPLCSV
DRVLCASPEYLAEFGVPDSLEQLIEHNCLFYKLDERTHDQWQFRRDGQEYKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTQALSKSLGQILAVKKS

Sequences:

>Translated_308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPLCSV
DRVLCASPEYLAEFGVPDSLEQLIEHNCLFYKLDERTHDQWQFRRDGQEYKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTQALSKSLGQILAVKKS
>Mature_308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLQVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPLCSV
DRVLCASPEYLAEFGVPDSLEQLIEHNCLFYKLDERTHDQWQFRRDGQEYKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTQALSKSLGQILAVKKS

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=35, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=32.5259515570934, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=30.3030303030303, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786401, Length=254, Percent_Identity=30.3149606299213, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789639, Length=265, Percent_Identity=30.188679245283, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=25.7246376811594, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=25.089605734767, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786448, Length=277, Percent_Identity=27.4368231046931, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=25.9649122807018, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=162, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=129, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790011, Length=309, Percent_Identity=26.537216828479, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34480; Mature: 34480

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQ
CCCHHEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPLCSVDRVLCASPEYLAEFGVPDSL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCHHH
EQLIEHNCLFYKLDERTHDQWQFRRDGQEYKVRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTQALSKSLG
CCHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QILAVKKS
HHEEECCC
>Mature Secondary Structure
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQ
CCCHHEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCCCCE
QVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPLCSVDRVLCASPEYLAEFGVPDSL
EEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCHHH
EQLIEHNCLFYKLDERTHDQWQFRRDGQEYKVRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTQALSKSLG
CCHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QILAVKKS
HHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]