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The map label for this gene is ubiB

Identifier: 126176087

GI number: 126176087

Start: 4574419

End: 4576068

Strand: Direct

Name: ubiB

Synonym: Sbal_3897

Alternate gene names: 126176087

Gene position: 4574419-4576068 (Clockwise)

Preceding gene: 126176086

Following gene: 126176088

Centisome position: 89.22

GC content: 46.55

Gene sequence:

>1650_bases
ATGACCCTTGCCAGTATCCGCCGCGGTTACCATGTCATCAAGACCTTGCTTCAGTACGGGTTAGATGACGTATTGCCGCC
AAAGATGACACCTTGGTACTTTAAACTCGCCCGTAATAGTCTGTTCTGGATCCGCAATAAGCATAAAAATAAGCCCGGTG
GCGAACGCTTAAAATTGGCGATGCAGGAACTCGGCCCCGTTTATATCAAGCTTGGGCAAATGCTCTCGACCCGCCGCGAT
TTACTCAGCGATGAATGGGCCAGTGAATTAGCCATGCTGCAAGACAAGGTGCCGCCGTTTGATGGTGCACTTGCCCGCCA
AGCGATTGAAGCTGAACTAAAAGCGCCGATTGAATCCCTATTCGATGACTTTAATGAAATACCGCTAGCCTCAGCCTCTA
TTTCTCAAGTGCATACCGCGACCCTAAAATCTAACGGTAAAGACGTCGTGCTTAAGGTGCTACGGCCGAATGTAGAAACT
AAGATTCAGGCCGATCTGCAGTTGATGTCGCAAACCGCCAAGTTGATTGAATATCTCCTAGGTGAAGGCAACCGCCTGCG
CCCAGCCGAAGTGATTGAAGATTACCGCGTGACCATTTTAGGTGAGTTAAACCTTAAGCTCGAAGCCTTAAACGCAGTCA
AGCTACGCAACAACTTCCTCGACTCAGATGCACTCTATGTGCCTTATGTCTATGAAGAGTTTTGCTATCCACGCCTAATG
GTGATGGAACGCATTTACGGTATATCTGTCTCAGATATTGCCGCCCTTAAAGCGCAAGGCACCAACTTTAAGTTATTGGC
TGAGCGCGGAGTAGAGCTGTTTTTCACCCAAGTGTTCCGCGATAACTTTTTCCATGCCGACATGCATCCGGGCAATATCT
TTATTTCCCGCGATCATCCTGAGAACCCTTATTACATTGGGCTCGATTGCGGCATCATGGGCACACTCAGCGAAGTCGAT
AAACGCTATCTCGCCGAGAATTTCCTCGCCTTCTTTAATCGCGATTATCACCGAATTGCCCAGCTCTATATTGAATCAGG
CTGGGTGTCGGAAAAAACCGATCTACAGGCCTTTGAACAGGCGATTAAAGTGGTGTGCGAACCTATGTTCAACAAGCCGC
TCGATGAGATTTCCTTTGGTCATGTGTTGCTGGAATTATTCCGCACTGCACGCCACTTCGATATCGTGGTGCAACCACAA
TTGGTATTGCTGGAAAAGACCTTACTCTATATCGAAGGCTTAGGTCGTCAGCTGTATCCGCAGTTGGATTTATGGCAAAC
CGCTAAACCGTTTTTAGAGCAGTGGATGGCCGACCAAGTGGGTCCTAAGGCTATGTTTAAAAAGGTATCCACAAAACTGC
CATATTGGGCTGATAAACTACCAGAATTCCCTGAACTGATTTACGATAACCTTAAGTTAGGCAGGAAATTGCTGAGTTCT
CAGCAACAAATGCTAGATAAGTATTTGAAATACCAGCAGCAGGCTCACAAGAGTAACTACTTGCTTATCACTTCTGCAGT
TTTATTGATCTGTGGCACGTTATTGATCAATAGAGACGCTACACTATGGACCCCTTATGTTTGTCTAGTTTCAGGCATTA
TATTGTGGTTTGTCGGATGGCGATCTAGGCCAAAGAATCGCAAATTTTAG

Upstream 100 bases:

>100_bases
CAATTGAGTTACTTCATTTTCGCGATCAAATGGATGATTTAGTTGCCGATACCCGCGCGATTGAACAACGGATTGCCCAA
TTAAGAGACCAAATTAAGCC

Downstream 100 bases:

>100_bases
CTAGCACTAATAAATCATAGGTTCATAATAGAACCGATATCAATTAAGAGGATACCTTCATGGGTGGTATTAGTATTTGG
CAACTTCTTATCGTTGCATT

Product: 2-polyprenylphenol 6-hydroxylase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRD
LLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVET
KIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVD
KRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQ
LVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF

Sequences:

>Translated_549_residues
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRD
LLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVET
KIQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVD
KRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQ
LVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF
>Mature_548_residues
TLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLAMQELGPVYIKLGQMLSTRRDL
LSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESLFDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVETK
IQADLQLMSQTAKLIEYLLGEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLMV
MERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHPENPYYIGLDCGIMGTLSEVDK
RYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQAIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQL
VLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSSQ
QQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGWRSRPKNRKF

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily

Homologues:

Organism=Homo sapiens, GI40254938, Length=254, Percent_Identity=28.3464566929134, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=26.9372693726937, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI217035081, Length=209, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI34147522, Length=220, Percent_Identity=27.7272727272727, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI2367309, Length=547, Percent_Identity=58.3180987202925, Blast_Score=652, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559152, Length=283, Percent_Identity=25.7950530035336, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555620, Length=469, Percent_Identity=21.7484008528785, Blast_Score=100, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325148, Length=469, Percent_Identity=26.226012793177, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323282, Length=305, Percent_Identity=27.8688524590164, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=212, Percent_Identity=29.2452830188679, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI22024280, Length=253, Percent_Identity=30.0395256916996, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24662575, Length=249, Percent_Identity=28.1124497991968, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIB_SHEB2 (B8E6B4)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002356400.1
- GeneID:   7086919
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_0443
- HOGENOM:   HBG593509
- OMA:   RIQRVVI
- ProtClustDB:   CLSK907541
- HAMAP:   MF_00414
- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232
- TIGRFAMs:   TIGR01982

Pfam domain/function: PF03109 ABC1; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 63377; Mature: 63245

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1749934c)-; HASH(0x1997cbc4)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLA
CCHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
MQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLL
HHHHHHCCCCCCHHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
CCCCCCCHHHHHCCCEEEEEEECCEEEHHHHHHHHHHCCCCCCCEECCHHHHHHCCHHHH
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHP
HHHHHHCCCHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEECCCCCCEEEEECCCC
ENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHCC
QLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGW
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRPKNRKF
CCCCCCCCH
>Mature Secondary Structure 
TLASIRRGYHVIKTLLQYGLDDVLPPKMTPWYFKLARNSLFWIRNKHKNKPGGERLKLA
CHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHH
MQELGPVYIKLGQMLSTRRDLLSDEWASELAMLQDKVPPFDGALARQAIEAELKAPIESL
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FDDFNEIPLASASISQVHTATLKSNGKDVVLKVLRPNVETKIQADLQLMSQTAKLIEYLL
HHHHHHCCCCCCHHHHHHHHHHHCCCHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GEGNRLRPAEVIEDYRVTILGELNLKLEALNAVKLRNNFLDSDALYVPYVYEEFCYPRLM
CCCCCCCHHHHHCCCEEEEEEECCEEEHHHHHHHHHHCCCCCCCEECCHHHHHHCCHHHH
VMERIYGISVSDIAALKAQGTNFKLLAERGVELFFTQVFRDNFFHADMHPGNIFISRDHP
HHHHHHCCCHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHCCCEECCCCCCEEEEECCCC
ENPYYIGLDCGIMGTLSEVDKRYLAENFLAFFNRDYHRIAQLYIESGWVSEKTDLQAFEQ
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
AIKVVCEPMFNKPLDEISFGHVLLELFRTARHFDIVVQPQLVLLEKTLLYIEGLGRQLYP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHCC
QLDLWQTAKPFLEQWMADQVGPKAMFKKVSTKLPYWADKLPEFPELIYDNLKLGRKLLSS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
QQQMLDKYLKYQQQAHKSNYLLITSAVLLICGTLLINRDATLWTPYVCLVSGIILWFVGW
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RSRPKNRKF
CCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA