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The map label for this gene is btuB [H]

Identifier: 126176074

GI number: 126176074

Start: 4561200

End: 4563593

Strand: Direct

Name: btuB [H]

Synonym: Sbal_3884

Alternate gene names: 126176074

Gene position: 4561200-4563593 (Clockwise)

Preceding gene: 126176069

Following gene: 126176075

Centisome position: 88.96

GC content: 49.54

Gene sequence:

>2394_bases
ATGCGTCTAGGGATTATCGCATTGGCAGTGTCATCCACACTGGCCATTCCAGCTGTTCAAGCCGAAGAACTACAGCCTGG
CTTCGAGAAAATCGAGATCATAGGTTCACGCATAGCGCTGCGCACGGCAACTGACAGTGTTGCCCCTGTAGACATTATCA
CTGCCGAGCAGCTCGAATCGACCGGCATGACTGAAACCGCTAAAGCACTGCAATTTGCCGCTCCAAGCTACAGCTTCCCA
TTCTCCTCAGTGACTGACGGTTCAGATGCGGTGCGCCCCGCGAGTTTGCGCGGCCTGTCACCCGACCACACCTTAGTACT
CGTTAACGGCAAACGTCGTCACGGCTCAGCGCTAGTGCATTTAAGTGGCACTGTGGGTAAAGGTTCATCTAACGTCGACT
TAAACGCTATCCCTATGACGGCGATTAAGCGCATCGAAATTTTGCGTGATGGTGCCTCGGCACAATACGGCTCGGATGCA
ATTGCCGGCGTCATCAACGTGGTGCTAAAGGACAGCGATCAAGGCGGTAGCATCTCGGCTCAAGCAGGACAAACCTACAT
AGGTGATGGCGAGCAATGGCGTGTGGGTGTAAACCACGGCATCAGTTTAAGTGACGATGGCTTTGTGAATGTCTCACTAG
AAGCCCATCATAAAGACAGCACTAACCGCGCCGGATTAGATGAACGTAAACAATATAATGATTTACCCGATGGATCAGCC
GATCCCCGCGAAGCCACATTTAACCGTAAGAGCCACCAGGTCGGCGATGCCGAATATGACAACTTAGGTCTATTCATCAA
CGCTGCCCAGCCCATCACAAAAGATGGCAAACTCTATGCGTTTGGTGGCATCAGCCAACGTGAGACTAAGTCAGGCGCCT
TTTACCGCCGCGCACTCGACGCCCGTAACTTAACTGAAATCTATCCAGATGGTTTCTTGCCGCAAATCAATCCTAAAATT
ATCGATGCGTCCTTAGTGCTGGGGTATGAATTCAGCCTAGGCGAGTGGAATATTGATACTTCGGCAGGCCATGGTGAAAA
CTCATTTAACTACAATATTGTTAATACCTTAAACGCCTCTTTAGGCCCAGATAGCCCAAACGAGTTTGACGCGGGCACAC
TCACGACCCGTGAAACCAATCTTAATATTGATGCTTCGCGCTACTTTGCCTTTGCCAATGACTCTGAAATCCTGTTTGCG
ACGGGTGTGTCGTGGCGCCAAAACGGCTATCAAATTGAAGCCGGCGAAACGGGTTCATACATCAATGGCGGTTACGACAA
CCGCGCTGCAGGCAGCCAAGGTTTCACTGGTTTTACCCCTGAGTCGCAAGTGGATGAAACCCTTGACAATACTGGCGTTT
ATGTCGAGCTTGAAAACCAGTTAACCAATGAGTTTTACTGGGCGGCGGCGCTGCGTTATGAAAACTATTCTGACTTTGGT
GGCAACACCAGTTGGAAGTTAGCGGGCCGTTACGACTTCACCGAAAACTTAGCCCTGCGCGGTACGATCAACACAGGCTT
TAGAGCGCCAAGCGTACAACAACTGTACTTCAGCAATATCTCGACGCTGTTTAATCCCGATCCTGTAACTGGTCAGCTGG
TGCCTATTGAGTCAGGCACTTTTAACACCCTATCGCCAGTGACCAAAGCACTGGGTATTAATGAGTTAGATCCCGAACTA
TCCCAGTCATTCAGTTTAGGCTTGGTGTACACCAATGACACAGGCTTAGCACTGACATTAGATGCCTATCAAATCTCCAT
CGATGATCGCATTATTCTGTCGAGCTCAGTGACGCCTAATGATTCGCCCGCCGTAGCGGCCGCGTTAGCGGGCACCAATG
CAGAATCGGCGCGCTTCTTTATCAACGCCGTCGATACCCGTACCCGTGGCGTTGACCTTGTAGTGAGCCAAGATTTTGAT
ATCGGCTCATGGGGTGATTTACGGGCTAACTTAGCCTATGCCTACAATAAGACTGAAATCCAAGATATTAATTTCCCAGA
GATTTTAGACGGACTCGGCCCTAAACTATTCGATAGCATTGAACAAACTCGCATGACCTCGGCGACACCGCATAACACGG
GTAACTTGGGCTTGACCCATGAGCTAGGCGACTTTAAGACCAATATTCGCCTCAGCTACTTTGGTGATTACACTGTCGGC
TATTCAACGGGTGATGTGAATTACAGCGATCAATGGGTGATGGATCTGTCGGTGAGATACGCGGCAACCGATGCGCTAAG
TTTCACCGCTGGGGTACAAAACCTGTTTGATGTGTATCCAGAAAAACGCCCTGATGACAATAACTTCGGAGGCATCTTCG
TCTACCCATTAACCAACACCCCGTTTGGTTTTAATGGTGGCTATTACTTCTTAGAAGCTAAATACACTTACTAA

Upstream 100 bases:

>100_bases
TGTTACAGCGATAACCTTCTCCACATTGAATTGTTACGTTATCTTTAATCTGCACTCCTAAGTTCGAGTATCGGGTTACA
AACATCATTGAGAGGTTTTT

Downstream 100 bases:

>100_bases
GCGCGTCTTAGCGAACAAAGTGACACTTGATATAAAAACAGGCCATGCTACGGCCTGTTTTTTTATGCCTAAAGCTTATG
TCCTAACGGCGACTATCTGA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MRLGIIALAVSSTLAIPAVQAEELQPGFEKIEIIGSRIALRTATDSVAPVDIITAEQLESTGMTETAKALQFAAPSYSFP
FSSVTDGSDAVRPASLRGLSPDHTLVLVNGKRRHGSALVHLSGTVGKGSSNVDLNAIPMTAIKRIEILRDGASAQYGSDA
IAGVINVVLKDSDQGGSISAQAGQTYIGDGEQWRVGVNHGISLSDDGFVNVSLEAHHKDSTNRAGLDERKQYNDLPDGSA
DPREATFNRKSHQVGDAEYDNLGLFINAAQPITKDGKLYAFGGISQRETKSGAFYRRALDARNLTEIYPDGFLPQINPKI
IDASLVLGYEFSLGEWNIDTSAGHGENSFNYNIVNTLNASLGPDSPNEFDAGTLTTRETNLNIDASRYFAFANDSEILFA
TGVSWRQNGYQIEAGETGSYINGGYDNRAAGSQGFTGFTPESQVDETLDNTGVYVELENQLTNEFYWAAALRYENYSDFG
GNTSWKLAGRYDFTENLALRGTINTGFRAPSVQQLYFSNISTLFNPDPVTGQLVPIESGTFNTLSPVTKALGINELDPEL
SQSFSLGLVYTNDTGLALTLDAYQISIDDRIILSSSVTPNDSPAVAAALAGTNAESARFFINAVDTRTRGVDLVVSQDFD
IGSWGDLRANLAYAYNKTEIQDINFPEILDGLGPKLFDSIEQTRMTSATPHNTGNLGLTHELGDFKTNIRLSYFGDYTVG
YSTGDVNYSDQWVMDLSVRYAATDALSFTAGVQNLFDVYPEKRPDDNNFGGIFVYPLTNTPFGFNGGYYFLEAKYTY

Sequences:

>Translated_797_residues
MRLGIIALAVSSTLAIPAVQAEELQPGFEKIEIIGSRIALRTATDSVAPVDIITAEQLESTGMTETAKALQFAAPSYSFP
FSSVTDGSDAVRPASLRGLSPDHTLVLVNGKRRHGSALVHLSGTVGKGSSNVDLNAIPMTAIKRIEILRDGASAQYGSDA
IAGVINVVLKDSDQGGSISAQAGQTYIGDGEQWRVGVNHGISLSDDGFVNVSLEAHHKDSTNRAGLDERKQYNDLPDGSA
DPREATFNRKSHQVGDAEYDNLGLFINAAQPITKDGKLYAFGGISQRETKSGAFYRRALDARNLTEIYPDGFLPQINPKI
IDASLVLGYEFSLGEWNIDTSAGHGENSFNYNIVNTLNASLGPDSPNEFDAGTLTTRETNLNIDASRYFAFANDSEILFA
TGVSWRQNGYQIEAGETGSYINGGYDNRAAGSQGFTGFTPESQVDETLDNTGVYVELENQLTNEFYWAAALRYENYSDFG
GNTSWKLAGRYDFTENLALRGTINTGFRAPSVQQLYFSNISTLFNPDPVTGQLVPIESGTFNTLSPVTKALGINELDPEL
SQSFSLGLVYTNDTGLALTLDAYQISIDDRIILSSSVTPNDSPAVAAALAGTNAESARFFINAVDTRTRGVDLVVSQDFD
IGSWGDLRANLAYAYNKTEIQDINFPEILDGLGPKLFDSIEQTRMTSATPHNTGNLGLTHELGDFKTNIRLSYFGDYTVG
YSTGDVNYSDQWVMDLSVRYAATDALSFTAGVQNLFDVYPEKRPDDNNFGGIFVYPLTNTPFGFNGGYYFLEAKYTY
>Mature_797_residues
MRLGIIALAVSSTLAIPAVQAEELQPGFEKIEIIGSRIALRTATDSVAPVDIITAEQLESTGMTETAKALQFAAPSYSFP
FSSVTDGSDAVRPASLRGLSPDHTLVLVNGKRRHGSALVHLSGTVGKGSSNVDLNAIPMTAIKRIEILRDGASAQYGSDA
IAGVINVVLKDSDQGGSISAQAGQTYIGDGEQWRVGVNHGISLSDDGFVNVSLEAHHKDSTNRAGLDERKQYNDLPDGSA
DPREATFNRKSHQVGDAEYDNLGLFINAAQPITKDGKLYAFGGISQRETKSGAFYRRALDARNLTEIYPDGFLPQINPKI
IDASLVLGYEFSLGEWNIDTSAGHGENSFNYNIVNTLNASLGPDSPNEFDAGTLTTRETNLNIDASRYFAFANDSEILFA
TGVSWRQNGYQIEAGETGSYINGGYDNRAAGSQGFTGFTPESQVDETLDNTGVYVELENQLTNEFYWAAALRYENYSDFG
GNTSWKLAGRYDFTENLALRGTINTGFRAPSVQQLYFSNISTLFNPDPVTGQLVPIESGTFNTLSPVTKALGINELDPEL
SQSFSLGLVYTNDTGLALTLDAYQISIDDRIILSSSVTPNDSPAVAAALAGTNAESARFFINAVDTRTRGVDLVVSQDFD
IGSWGDLRANLAYAYNKTEIQDINFPEILDGLGPKLFDSIEQTRMTSATPHNTGNLGLTHELGDFKTNIRLSYFGDYTVG
YSTGDVNYSDQWVMDLSVRYAATDALSFTAGVQNLFDVYPEKRPDDNNFGGIFVYPLTNTPFGFNGGYYFLEAKYTY

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790405, Length=139, Percent_Identity=30.2158273381295, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86401; Mature: 86401

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGIIALAVSSTLAIPAVQAEELQPGFEKIEIIGSRIALRTATDSVAPVDIITAEQLES
CCEEEEEEEECCCEECCCCCHHHCCCCHHHHHEECCEEEEEECCCCCCCEEEEEHHHHHH
TGMTETAKALQFAAPSYSFPFSSVTDGSDAVRPASLRGLSPDHTLVLVNGKRRHGSALVH
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCCCEEEE
LSGTVGKGSSNVDLNAIPMTAIKRIEILRDGASAQYGSDAIAGVINVVLKDSDQGGSISA
EECCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCCEEEC
QAGQTYIGDGEQWRVGVNHGISLSDDGFVNVSLEAHHKDSTNRAGLDERKQYNDLPDGSA
CCCCEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCC
DPREATFNRKSHQVGDAEYDNLGLFINAAQPITKDGKLYAFGGISQRETKSGAFYRRALD
CCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHC
ARNLTEIYPDGFLPQINPKIIDASLVLGYEFSLGEWNIDTSAGHGENSFNYNIVNTLNAS
CCCCHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCEECCCCCCCCCCCCEEEEEEEEECC
LGPDSPNEFDAGTLTTRETNLNIDASRYFAFANDSEILFATGVSWRQNGYQIEAGETGSY
CCCCCCCCCCCCEEEEEECCCCEEHHHEEEEECCCCEEEEECCCCCCCCEEEECCCCCCC
INGGYDNRAAGSQGFTGFTPESQVDETLDNTGVYVELENQLTNEFYWAAALRYENYSDFG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GNTSWKLAGRYDFTENLALRGTINTGFRAPSVQQLYFSNISTLFNPDPVTGQLVPIESGT
CCCEEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHCHHHHCCCCCCCEEEEEECCCC
FNTLSPVTKALGINELDPELSQSFSLGLVYTNDTGLALTLDAYQISIDDRIILSSSVTPN
CCHHHHHHHHCCCCCCCHHHHCCEEEEEEEECCCCEEEEEEEEEEEECCEEEEECCCCCC
DSPAVAAALAGTNAESARFFINAVDTRTRGVDLVVSQDFDIGSWGDLRANLAYAYNKTEI
CCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEE
QDINFPEILDGLGPKLFDSIEQTRMTSATPHNTGNLGLTHELGDFKTNIRLSYFGDYTVG
ECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCEEEE
YSTGDVNYSDQWVMDLSVRYAATDALSFTAGVQNLFDVYPEKRPDDNNFGGIFVYPLTNT
EECCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
PFGFNGGYYFLEAKYTY
CCCCCCCEEEEEEEECC
>Mature Secondary Structure
MRLGIIALAVSSTLAIPAVQAEELQPGFEKIEIIGSRIALRTATDSVAPVDIITAEQLES
CCEEEEEEEECCCEECCCCCHHHCCCCHHHHHEECCEEEEEECCCCCCCEEEEEHHHHHH
TGMTETAKALQFAAPSYSFPFSSVTDGSDAVRPASLRGLSPDHTLVLVNGKRRHGSALVH
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEEECCCCCCCEEEE
LSGTVGKGSSNVDLNAIPMTAIKRIEILRDGASAQYGSDAIAGVINVVLKDSDQGGSISA
EECCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCCCCEEEC
QAGQTYIGDGEQWRVGVNHGISLSDDGFVNVSLEAHHKDSTNRAGLDERKQYNDLPDGSA
CCCCEEECCCCEEEEECCCCCEECCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCC
DPREATFNRKSHQVGDAEYDNLGLFINAAQPITKDGKLYAFGGISQRETKSGAFYRRALD
CCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHC
ARNLTEIYPDGFLPQINPKIIDASLVLGYEFSLGEWNIDTSAGHGENSFNYNIVNTLNAS
CCCCHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCEECCCCCCCCCCCCEEEEEEEEECC
LGPDSPNEFDAGTLTTRETNLNIDASRYFAFANDSEILFATGVSWRQNGYQIEAGETGSY
CCCCCCCCCCCCEEEEEECCCCEEHHHEEEEECCCCEEEEECCCCCCCCEEEECCCCCCC
INGGYDNRAAGSQGFTGFTPESQVDETLDNTGVYVELENQLTNEFYWAAALRYENYSDFG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEECCCCCCC
GNTSWKLAGRYDFTENLALRGTINTGFRAPSVQQLYFSNISTLFNPDPVTGQLVPIESGT
CCCEEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHCHHHHCCCCCCCEEEEEECCCC
FNTLSPVTKALGINELDPELSQSFSLGLVYTNDTGLALTLDAYQISIDDRIILSSSVTPN
CCHHHHHHHHCCCCCCCHHHHCCEEEEEEEECCCCEEEEEEEEEEEECCEEEEECCCCCC
DSPAVAAALAGTNAESARFFINAVDTRTRGVDLVVSQDFDIGSWGDLRANLAYAYNKTEI
CCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEE
QDINFPEILDGLGPKLFDSIEQTRMTSATPHNTGNLGLTHELGDFKTNIRLSYFGDYTVG
ECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCEEEE
YSTGDVNYSDQWVMDLSVRYAATDALSFTAGVQNLFDVYPEKRPDDNNFGGIFVYPLTNT
EECCCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
PFGFNGGYYFLEAKYTY
CCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA