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The map label for this gene is dctS [H]

Identifier: 126176052

GI number: 126176052

Start: 4535522

End: 4537333

Strand: Reverse

Name: dctS [H]

Synonym: Sbal_3861

Alternate gene names: 126176052

Gene position: 4537333-4535522 (Counterclockwise)

Preceding gene: 126176062

Following gene: 126176046

Centisome position: 88.49

GC content: 50.94

Gene sequence:

>1812_bases
ATGGCGACGGGCTCTTGGTGTAAAGCGGTAGTGATGGGATTATGCCTAAGTGTAATTGGGCTGAATCCGTCCTATGCCGA
TGACGTGCCACAGGTGAACCACTTTAAAGTCGGAGTGTTGGCCAACCACGGCGTATTACAGGCCAAGCAGCGATGGCAAC
CTATGATGGATTACCTGACTGAACAAGTGCCCAATAGCCATTTTGAAGTGGTGCCCGTTGACTTTAATGGTATGCGTAGC
CAGTTACTCGGCCATGATTTGCAGTTTATCGTCACCAACCCCGGGCAATATCTGCATCTAAGCAATAACTTCCCGCTGTC
TTGGCTCGCGACGATGAAGAGCCGCAAGCATCAGGGCAGTACTTTTACCATAGGCGCAACTATTATTGTCCGCGCCGATA
GCCCTATCCGCACCCTGCAGGATTTGCGCGGGCGCAATGTGGTCGCCAGTGATCCGCAGGCATTAGGCGGGTATCAGGCG
GCCATGGGGTTACTTCATAAAATGGGCTTTTTACCCGAACAGTTTTTTGGGCAAGTGCGCTTTCTCGGTTTTCCATTGGA
GCCGCTTGTCTATCAAGTCCGTGATGGCAGCGCCGATGCCGCCATCGCGCCTTTTTGCACCTTAGAGGAAATGATCGCAA
CGGGCCTAGTTAATCAGGCCGATTATCGGGTGATCCACCCGACTAACCCCGCAGGATATGACTGCGAGGTCAGCACTCAG
TTATACCCCAACTGGTCATTCGCCGCAGCGGATACGGTTGCCCCTAAGCTGACGATGGCGATCACCCGCGCCTTATTCGA
TTTACCCGCTGACCATGTCGCTGCCATTACCGCCGATACCTTGGGCTGGACGGCACCAGTGAGTCAGTTGAAAGTCATTG
AGTTATTTAAGGAATTACAACTGCAAGGTGCGTCGCCGCCACTCTATCAAACTGTATACAAATGGATGGCGAAAAATAAA
GAATGGGGCGGTGTACTGCTATTAATCTTCATTATTTCGACTATTTATCACCTCTGGCTCGAATATAAGTTTCGCCAGAA
AAGCGAGTTCTTACTCAATACTGAGCGGCAATTAAAGGATAAGGCATTGCAGCTTGAGCGATTGCAAAGCGCGGCAATTC
TGGGGGAAATTGGCGCTGGCCTTGCCCATGAACTCAATCAACCCATAGCCGCCATTACCCAATACAGCGAAGGCGCCATG
CTGCAATTGGAAAGGCTTGGGCAAGATAATCCCGAACTTTATGATGTACTCGGGAAAATTAATGCGCAGTCGATTCGCGC
GGGTGCGGTTGTGCACCGTATTCGCGGTTTACTCAAGCGGCGTCAGGCCAAGACTGAGCCTTTAGATATCGTGCTGGTGG
TGAAGGAGGCGTTAGCTTTACTGCGGCGCGAGTTAGATCGGGCCAATGTGCAAGTGAATGTGCGAGTGCAGGGCGAGCCC
TTTGAGCTGATGGGCGATAGCGTTGGCTTAAGTCAAATGTGGGTCAATCTCGTGAAAAATAGTTTAGATGCACTAGAGAC
CTGCGGCGATAACCGCGTGCGGCAATTATGGATCGATATCTATTTTCAACCGAATGAAATCAAAGTGTTAGTGATTGATA
ATGGTGAAGGGTTACAGGGACAGGCGAGTGAGTTGATGGCATCATTCGCCTCAACCAAAGATGCGGGATTAGGGCTTGGC
TTAGCCATCTGTAAGGATGTGGTCACCCGCCATCACGGCAGCATTCAAATCGAAAACTGTCAGCAATCCACGCAAGCTTT
ACTGCCTTGGCAGCAGGGTTGTGTGGTGACTGTGGTCTTACCTAAGGGCTAA

Upstream 100 bases:

>100_bases
ATCTTAGGGCAGAAACCAGAGTTTGGCGGCATTTCACAGCTTGATTTTTATCTGCGAGTTAAAGTCGTTTAATAGCATAC
AAGACAGGGTAATAGCGGCG

Downstream 100 bases:

>100_bases
TGTGCATAGCTCCACTTAGCTGCAGATCAATTGTATTAGGGCAGTGGATAGTCTTGGGCGAATTGACCGAGTTTTTCCAC
TAAAAACGCTATGGTGCGCC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MATGSWCKAVVMGLCLSVIGLNPSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRS
QLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQA
AMGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTNPAGYDCEVSTQ
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNK
EWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAM
LQLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
FELMGDSVGLSQMWVNLVKNSLDALETCGDNRVRQLWIDIYFQPNEIKVLVIDNGEGLQGQASELMASFASTKDAGLGLG
LAICKDVVTRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG

Sequences:

>Translated_603_residues
MATGSWCKAVVMGLCLSVIGLNPSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRS
QLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQA
AMGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTNPAGYDCEVSTQ
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNK
EWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAM
LQLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
FELMGDSVGLSQMWVNLVKNSLDALETCGDNRVRQLWIDIYFQPNEIKVLVIDNGEGLQGQASELMASFASTKDAGLGLG
LAICKDVVTRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG
>Mature_602_residues
ATGSWCKAVVMGLCLSVIGLNPSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLTEQVPNSHFEVVPVDFNGMRSQ
LLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGSTFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAA
MGLLHKMGFLPEQFFGQVRFLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTNPAGYDCEVSTQL
YPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQLQGASPPLYQTVYKWMAKNKE
WGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKDKALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAML
QLERLGQDNPELYDVLGKINAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEPF
ELMGDSVGLSQMWVNLVKNSLDALETCGDNRVRQLWIDIYFQPNEIKVLVIDNGEGLQGQASELMASFASTKDAGLGLGL
AICKDVVTRHHGSIQIENCQQSTQALLPWQQGCVVTVVLPKG

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=25.4980079681275, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=23.3082706766917, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66743; Mature: 66612

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGSWCKAVVMGLCLSVIGLNPSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLT
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
EQVPNSHFEVVPVDFNGMRSQLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGS
HHCCCCCEEEEEECCCHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCC
TFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAAMGLLHKMGFLPEQFFGQVR
EEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCHHHHCCEE
FLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTNPAGYDCEVSTQ
EECCCHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHH
LQGASPPLYQTVYKWMAKNKEWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKD
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
KALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAMLQLERLGQDNPELYDVLGKI
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHCC
NAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELMGDSVGLSQMWVNLVKNSLDALETCGDNRVRQLWIDIYFQPNEIKVLVIDNGEGLQG
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCC
QASELMASFASTKDAGLGLGLAICKDVVTRHHGSIQIENCQQSTQALLPWQQGCVVTVVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCEEEEEE
PKG
CCC
>Mature Secondary Structure 
ATGSWCKAVVMGLCLSVIGLNPSYADDVPQVNHFKVGVLANHGVLQAKQRWQPMMDYLT
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
EQVPNSHFEVVPVDFNGMRSQLLGHDLQFIVTNPGQYLHLSNNFPLSWLATMKSRKHQGS
HHCCCCCEEEEEECCCHHHHHHCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCC
TFTIGATIIVRADSPIRTLQDLRGRNVVASDPQALGGYQAAMGLLHKMGFLPEQFFGQVR
EEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCHHHCHHHHHHHHHHHHCCCCHHHHCCEE
FLGFPLEPLVYQVRDGSADAAIAPFCTLEEMIATGLVNQADYRVIHPTNPAGYDCEVSTQ
EECCCHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEECCE
LYPNWSFAAADTVAPKLTMAITRALFDLPADHVAAITADTLGWTAPVSQLKVIELFKELQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHH
LQGASPPLYQTVYKWMAKNKEWGGVLLLIFIISTIYHLWLEYKFRQKSEFLLNTERQLKD
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
KALQLERLQSAAILGEIGAGLAHELNQPIAAITQYSEGAMLQLERLGQDNPELYDVLGKI
HHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHCC
NAQSIRAGAVVHRIRGLLKRRQAKTEPLDIVLVVKEALALLRRELDRANVQVNVRVQGEP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELMGDSVGLSQMWVNLVKNSLDALETCGDNRVRQLWIDIYFQPNEIKVLVIDNGEGLQG
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCC
QASELMASFASTKDAGLGLGLAICKDVVTRHHGSIQIENCQQSTQALLPWQQGCVVTVVL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCCCCEEEEEE
PKG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]