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The map label for this gene is qorA [H]

Identifier: 126175925

GI number: 126175925

Start: 4366802

End: 4367803

Strand: Reverse

Name: qorA [H]

Synonym: Sbal_3731

Alternate gene names: 126175925

Gene position: 4367803-4366802 (Counterclockwise)

Preceding gene: 126175927

Following gene: 126175924

Centisome position: 85.19

GC content: 54.59

Gene sequence:

>1002_bases
ATGTCAGCTTTACCAAGCGAATACACCCATATCCATGTTGAGCAACCCGGGACGCCCGAGGTGATGCAGCTATCGCGCTC
GCCTTTGCCTGTGCCAGCGTCTGGCCAAGTGTTGATCCGCGTGCATGCAGCAGGAGTAAATGGCCCCGATGTCAAACAAA
GGGTAGGTGCTTATCCACCACCACCGGGTGCATCACCGATTATTGGTCTTGAAGTCGCGGGTGATATTTGTGCCCTCGGT
GACGGCGTGAGCCAATGGCAAATCGGCGACAAGGTTTGCGCCTTAGTACCGGGCGGTGGCTATGGTGAGTACGTGCTCAC
CTATGCTGCCCACTGTTTACCTATTCCAACGGGCTTTAGTTATGTGCAGGCCGCCGCGCTGCCAGAAACCTTCTTCACCG
TATGGGGCAACCTGTTTATGCGTGCGGGACTGAAAGCGGGCGAGACTGTGCTGATCCACGGCGGCTCGGGCGGTATCGGC
AGTACGGCCATTCAACTTGCCAGCGCCTTAGGCTCAAAAGTCATTGCCACAACGGGGCAAGATGAGAAGCGCGATTATTG
CTTGAGCCTTGGCGCTACTGAAGTCATCAACTATCGCACCCACAACTTTGTTGAGCCCGTCATGACGCTCACCCAAGATA
AGGGCGTGAACGTGGTCTTTGATATCGCGGGTGGCGATTTTATTAATCTCGATTTACAAGCCTTAGCGCTGGACGGCCGT
ATGGTGTCGGTGGCGATGCAACGTGGCCCTAAGGCCGAAGTGGAGATTTTCCGTCTGATGGCAAAACGTATTATGTGGAC
AGGGTCGACCCTAAGACCACAAAGCGTGGAGGCTAAAGCCACTATTGCCGCCGAATTATTTGAGAAAGTCTGGCCGCTGT
TAAACGCCCATAAAATTGTGCCCAATATTTTTGCGACCTTCCCATTAGGCGAAGCCGCGAAAGCCCATGCGCTGATGGAG
TCGGGTGAGCACAGGGGCAAGGTGGTACTGACGGTCATTTAG

Upstream 100 bases:

>100_bases
GCCGCATTAAGGTTAGATGCACTTTTCCGCAGTTAGCACTCGAACCCTGAGATGCTAAGCCATCTGCGATGAGGTCGATG
CCATTCCCAAAGGAGCTTTT

Downstream 100 bases:

>100_bases
GCTCGGCATACTGCTTTGGCTGCGATGCATCGTTTAGGTCGCGGCCATTTGAGGCAAGTCTGAGAGCGTTCAGGCAAAAT
CGTGGCTGAGTAACGTAGGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSALPSEYTHIHVEQPGTPEVMQLSRSPLPVPASGQVLIRVHAAGVNGPDVKQRVGAYPPPPGASPIIGLEVAGDICALG
DGVSQWQIGDKVCALVPGGGYGEYVLTYAAHCLPIPTGFSYVQAAALPETFFTVWGNLFMRAGLKAGETVLIHGGSGGIG
STAIQLASALGSKVIATTGQDEKRDYCLSLGATEVINYRTHNFVEPVMTLTQDKGVNVVFDIAGGDFINLDLQALALDGR
MVSVAMQRGPKAEVEIFRLMAKRIMWTGSTLRPQSVEAKATIAAELFEKVWPLLNAHKIVPNIFATFPLGEAAKAHALME
SGEHRGKVVLTVI

Sequences:

>Translated_333_residues
MSALPSEYTHIHVEQPGTPEVMQLSRSPLPVPASGQVLIRVHAAGVNGPDVKQRVGAYPPPPGASPIIGLEVAGDICALG
DGVSQWQIGDKVCALVPGGGYGEYVLTYAAHCLPIPTGFSYVQAAALPETFFTVWGNLFMRAGLKAGETVLIHGGSGGIG
STAIQLASALGSKVIATTGQDEKRDYCLSLGATEVINYRTHNFVEPVMTLTQDKGVNVVFDIAGGDFINLDLQALALDGR
MVSVAMQRGPKAEVEIFRLMAKRIMWTGSTLRPQSVEAKATIAAELFEKVWPLLNAHKIVPNIFATFPLGEAAKAHALME
SGEHRGKVVLTVI
>Mature_332_residues
SALPSEYTHIHVEQPGTPEVMQLSRSPLPVPASGQVLIRVHAAGVNGPDVKQRVGAYPPPPGASPIIGLEVAGDICALGD
GVSQWQIGDKVCALVPGGGYGEYVLTYAAHCLPIPTGFSYVQAAALPETFFTVWGNLFMRAGLKAGETVLIHGGSGGIGS
TAIQLASALGSKVIATTGQDEKRDYCLSLGATEVINYRTHNFVEPVMTLTQDKGVNVVFDIAGGDFINLDLQALALDGRM
VSVAMQRGPKAEVEIFRLMAKRIMWTGSTLRPQSVEAKATIAAELFEKVWPLLNAHKIVPNIFATFPLGEAAKAHALMES
GEHRGKVVLTVI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=327, Percent_Identity=35.474006116208, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI22538444, Length=327, Percent_Identity=35.474006116208, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=33.8414634146341, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=33.8414634146341, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI194239676, Length=199, Percent_Identity=39.1959798994975, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI24308257, Length=329, Percent_Identity=27.9635258358663, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI28557745, Length=255, Percent_Identity=32.5490196078431, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=27.3311897106109, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=27.4760383386581, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI47519420, Length=366, Percent_Identity=27.0491803278689, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI197927207, Length=185, Percent_Identity=32.972972972973, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226059159, Length=110, Percent_Identity=33.6363636363636, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI226059133, Length=110, Percent_Identity=33.6363636363636, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI226056130, Length=110, Percent_Identity=33.6363636363636, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=32.6219512195122, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788073, Length=241, Percent_Identity=30.2904564315353, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17507255, Length=324, Percent_Identity=29.320987654321, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71987554, Length=186, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=313, Percent_Identity=24.6006389776358, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=354, Percent_Identity=27.1186440677966, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=288, Percent_Identity=26.0416666666667, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=282, Percent_Identity=25.531914893617, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=24.6987951807229, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=322, Percent_Identity=25.4658385093168, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581345, Length=341, Percent_Identity=27.5659824046921, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221330659, Length=270, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920632, Length=270, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45550423, Length=310, Percent_Identity=24.8387096774194, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35276; Mature: 35145

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALPSEYTHIHVEQPGTPEVMQLSRSPLPVPASGQVLIRVHAAGVNGPDVKQRVGAYPP
CCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCC
PPGASPIIGLEVAGDICALGDGVSQWQIGDKVCALVPGGGYGEYVLTYAAHCLPIPTGFS
CCCCCCEEEEEECCCEEECCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHEECCCCHH
YVQAAALPETFFTVWGNLFMRAGLKAGETVLIHGGSGGIGSTAIQLASALGSKVIATTGQ
HHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCC
DEKRDYCLSLGATEVINYRTHNFVEPVMTLTQDKGVNVVFDIAGGDFINLDLQALALDGR
CCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEECCE
MVSVAMQRGPKAEVEIFRLMAKRIMWTGSTLRPQSVEAKATIAAELFEKVWPLLNAHKIV
EEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PNIFATFPLGEAAKAHALMESGEHRGKVVLTVI
HHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
SALPSEYTHIHVEQPGTPEVMQLSRSPLPVPASGQVLIRVHAAGVNGPDVKQRVGAYPP
CCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCC
PPGASPIIGLEVAGDICALGDGVSQWQIGDKVCALVPGGGYGEYVLTYAAHCLPIPTGFS
CCCCCCEEEEEECCCEEECCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHHEECCCCHH
YVQAAALPETFFTVWGNLFMRAGLKAGETVLIHGGSGGIGSTAIQLASALGSKVIATTGQ
HHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEECCC
DEKRDYCLSLGATEVINYRTHNFVEPVMTLTQDKGVNVVFDIAGGDFINLDLQALALDGR
CCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEECCE
MVSVAMQRGPKAEVEIFRLMAKRIMWTGSTLRPQSVEAKATIAAELFEKVWPLLNAHKIV
EEEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PNIFATFPLGEAAKAHALMESGEHRGKVVLTVI
HHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]