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The map label for this gene is bla [H]

Identifier: 126175719

GI number: 126175719

Start: 4141455

End: 4142342

Strand: Reverse

Name: bla [H]

Synonym: Sbal_3522

Alternate gene names: 126175719

Gene position: 4142342-4141455 (Counterclockwise)

Preceding gene: 126175725

Following gene: 126175717

Centisome position: 80.79

GC content: 47.97

Gene sequence:

>888_bases
ATGCGTTCGTTCGCCATATCGACTGTGTTGGTGATGTCCTCACTGTTAGCGTCGTCAATCATAGCTGCCCCGACATTTGC
CTCAACAGCGGCGAAGACGGAGTGGCAAGAAACCCGCAGTTGGGATGCCATTTTTACTCAGCACCAAGTTGAACTGAAAC
AAGCTAAGCAACAACAAGTTAAACCGCAAAAAACTAAGTCCCAGCAAGCCTCGGGCGTGGTGGTGCTGTGGAACGAAAAC
AAGCAACAGGGATATACCAACAGTCTCAAACGTGCCAATCAAGGTTTTTTACCGGCATCGACCTTTAAAATCCCTAATAG
CTTGATTGCGCTCGAGTTGGGTGTGGTGAAGGATGAGCATCAAGTGTTTAAATGGGATGGTAAAAGTCGTGATATCGACA
CTTGGAATCGTGACCACAACTTGATTACCGGGATGAAGTATTCGGTTGTGCCTGTCTATCAAGAGTTTGCCCGCCAAATA
GGTGAGGCGCGGATGTCGAAGATGATCGCCTCCTTCGATTATGGCAATGAGGATATCTCGGGTAACTTAGATAGCTTTTG
GCTCGATGGCGGTATTCGGATTTCGGCCACTGAGCAAATTGATTTCCTGCGCCGGCTTTATCACAACAAGATCCATGCCT
CAGAGCGCAGTCAACGAATCGTTAAGCAGGCCATGCTCACCGAGGCGAATTCTGACTATATTATTCGCGCAAAAACCGGC
TATGCGGTCAGAGCTGAACCAAGTATTGGCTGGTGGGTGGGTTGGGTAGAACTCGATGATAATGTGTGGTTTTTTGCAAT
GAATATGGATATACCCGACGCCGCCGGTTTGCCATTGCGTCAAGCCATCACGAAGGAAGTTTTAAAACTGGAACACGTTA
TTCCTTAG

Upstream 100 bases:

>100_bases
CAATTGATCAGCAGTTTGCTAGGGCATGCTAAAACGCTAAGTGATAGCCTTAAGCACTTTTTTAGTTCATTGGATTTTTT
GTTTTCTACAAGGAGACTTT

Downstream 100 bases:

>100_bases
GTCATGCTAGGTCGCGTCTCTAACTTAAAACCTTGCAGTATTGCGTATTGAATTTAAGTCGGATACTTGGCTGACATGAA
TCATGATGCTAAAAGCCTAG

Product: Beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase PSE-2 [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVELKQAKQQQVKPQKTKSQQASGVVVLWNEN
KQQGYTNSLKRANQGFLPASTFKIPNSLIALELGVVKDEHQVFKWDGKSRDIDTWNRDHNLITGMKYSVVPVYQEFARQI
GEARMSKMIASFDYGNEDISGNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP

Sequences:

>Translated_295_residues
MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVELKQAKQQQVKPQKTKSQQASGVVVLWNEN
KQQGYTNSLKRANQGFLPASTFKIPNSLIALELGVVKDEHQVFKWDGKSRDIDTWNRDHNLITGMKYSVVPVYQEFARQI
GEARMSKMIASFDYGNEDISGNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP
>Mature_295_residues
MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVELKQAKQQQVKPQKTKSQQASGVVVLWNEN
KQQGYTNSLKRANQGFLPASTFKIPNSLIALELGVVKDEHQVFKWDGKSRDIDTWNRDHNLITGMKYSVVPVYQEFARQI
GEARMSKMIASFDYGNEDISGNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP

Specific function: Hydrolyzes both carbenicillin and oxacillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 33496; Mature: 33496

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVELKQAKQQQV
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
KPQKTKSQQASGVVVLWNENKQQGYTNSLKRANQGFLPASTFKIPNSLIALELGVVKDEH
CCHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHCCCCCEEEEEEEEEECCC
QVFKWDGKSRDIDTWNRDHNLITGMKYSVVPVYQEFARQIGEARMSKMIASFDYGNEDIS
EEEEECCCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
CCCCCEEECCCEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEECC
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP
EEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSFAISTVLVMSSLLASSIIAAPTFASTAAKTEWQETRSWDAIFTQHQVELKQAKQQQV
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
KPQKTKSQQASGVVVLWNENKQQGYTNSLKRANQGFLPASTFKIPNSLIALELGVVKDEH
CCHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHCCCCCEEEEEEEEEECCC
QVFKWDGKSRDIDTWNRDHNLITGMKYSVVPVYQEFARQIGEARMSKMIASFDYGNEDIS
EEEEECCCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GNLDSFWLDGGIRISATEQIDFLRRLYHNKIHASERSQRIVKQAMLTEANSDYIIRAKTG
CCCCCEEECCCEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEECC
YAVRAEPSIGWWVGWVELDDNVWFFAMNMDIPDAAGLPLRQAITKEVLKLEHVIP
EEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3126705; 11188693 [H]