Click here to switch to the map view.

The map label for this gene is dpiA [H]

Identifier: 126175628

GI number: 126175628

Start: 4022443

End: 4023123

Strand: Reverse

Name: dpiA [H]

Synonym: Sbal_3431

Alternate gene names: 126175628

Gene position: 4023123-4022443 (Counterclockwise)

Preceding gene: 126175629

Following gene: 126175625

Centisome position: 78.46

GC content: 49.63

Gene sequence:

>681_bases
ATGCATACAGTGATCATCGTCGAGGATGAAGTCGAAGTCGCCCATTTGGTTGCGCAATATTTGTTCTCGACCAATCGTTA
TAAAGTGATTGGCATGGCGAGCGATATCTGCACGGCGCGGTCTTTACTGGGCGCTATCACGCCTGACCTCTTACTGTTAG
ACGTGTATTTACCCGACGGTAATGGTTTGAATTTACTGGCAGAATTACGCAGCCAAGGGATCCGTAGCGAAGTGGTATTG
CTCACTGCGGCCAAAGAAGTGCAGATTTTAGAAAAAGCCATGCAGTTAGGCGTGTTCGATTTTCTGGTAAAACCTGTACT
CTTGAGTCGGTTAGACCAAGCTTTGAGTCGATTCGAGAGTCGCCAGCTCAAACTTTCTGCAACAGAAGAGCTGACTCAAT
CCGTGGTCGATGCCTTTATGGAAGTGCCGATAGGGACGACCAAGGCTGCTGCTCGTTTGCCAAAGGGGGTCGATCAATTG
ACCCTACAGAAAATTCGCGAAGTGTTTGATGCTAAGCCGCAAGATAAACTTACGGCGCAAATGGTGGGTGAAAAGCTAGG
CGTTAGCCGTTCTACTGCGCGGCGTTATTTAGAGTTTTTGTTGGAATGCAATGAGCTGGCGGCGGATCAGAGTTATGGCT
CCATCGGCCGCCCCGAACGTTGCTACCACAGAGTGCGCTAG

Upstream 100 bases:

>100_bases
TGCATACCGTCATGATTGTTGCGGACCAAGTTGCGCGTGTTGCTGAGTTAACCGCACCGTATTTGTTTCCTGAACTTCTG
CCTGAAGTAGGTATTGTTTA

Downstream 100 bases:

>100_bases
TCTTACTATTCAGCTTTTAGCTTTTCTACTTTAAGAAGTTAGTCCACCTTGACCCTTTCAAGCTGCCACTCTGGCAGCTT
AGAGGTTAAGTCTGGGATTA

Product: response regulator receiver/unknown domain-containing protein

Products: NA

Alternate protein names: Destabilizer of plasmid inheritance [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MHTVIIVEDEVEVAHLVAQYLFSTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGIRSEVVL
LTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFESRQLKLSATEELTQSVVDAFMEVPIGTTKAAARLPKGVDQL
TLQKIREVFDAKPQDKLTAQMVGEKLGVSRSTARRYLEFLLECNELAADQSYGSIGRPERCYHRVR

Sequences:

>Translated_226_residues
MHTVIIVEDEVEVAHLVAQYLFSTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGIRSEVVL
LTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFESRQLKLSATEELTQSVVDAFMEVPIGTTKAAARLPKGVDQL
TLQKIREVFDAKPQDKLTAQMVGEKLGVSRSTARRYLEFLLECNELAADQSYGSIGRPERCYHRVR
>Mature_226_residues
MHTVIIVEDEVEVAHLVAQYLFSTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGIRSEVVL
LTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFESRQLKLSATEELTQSVVDAFMEVPIGTTKAAARLPKGVDQL
TLQKIREVFDAKPQDKLTAQMVGEKLGVSRSTARRYLEFLLECNELAADQSYGSIGRPERCYHRVR

Specific function: Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox c

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=221, Percent_Identity=37.5565610859729, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1790566, Length=220, Percent_Identity=29.0909090909091, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787487, Length=164, Percent_Identity=33.5365853658537, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=31.6239316239316, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25163; Mature: 25163

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTVIIVEDEVEVAHLVAQYLFSTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDG
CCEEEEEECCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCC
NGLNLLAELRSQGIRSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFES
CCHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLKLSATEELTQSVVDAFMEVPIGTTKAAARLPKGVDQLTLQKIREVFDAKPQDKLTAQ
HCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
MVGEKLGVSRSTARRYLEFLLECNELAADQSYGSIGRPERCYHRVR
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MHTVIIVEDEVEVAHLVAQYLFSTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDG
CCEEEEEECCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCC
NGLNLLAELRSQGIRSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFES
CCHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLKLSATEELTQSVVDAFMEVPIGTTKAAARLPKGVDQLTLQKIREVFDAKPQDKLTAQ
HCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
MVGEKLGVSRSTARRYLEFLLECNELAADQSYGSIGRPERCYHRVR
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]