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The map label for this gene is bdlA [H]

Identifier: 126175574

GI number: 126175574

Start: 3951625

End: 3952932

Strand: Reverse

Name: bdlA [H]

Synonym: Sbal_3377

Alternate gene names: 126175574

Gene position: 3952932-3951625 (Counterclockwise)

Preceding gene: 126175575

Following gene: 126175570

Centisome position: 77.09

GC content: 45.64

Gene sequence:

>1308_bases
ATGTTGTTTACGAGCAAAAAGAGAAATAGTGATATCAAAATGGTCGATGCTGAACACTTTAAGTATTTAACATCAATTGA
AGACGAATTAAATGCGGTTAAGGCCAATACTGCCTACATTAGTTTTAGTGCCGATGGCATTATTTTGGACGCTAACGATC
TGTTTTTGTCGGCTGTGGGTTATACATTGGCTGATATTCTGGGTAAACATCACCGTATTTTCTGCGATAAAAGTTACACC
CTATCATCTGAATATCAGCAGTTCTGGCGCGATCTCGCCGCAGGTAAATCTATCCGCGGTACTTTCTTACGCTTCAAACA
AGATAAACAACCCATCTACTTAGAGGCGAGTTATTTCCCGATTGTTGATGGCAGCGGTAAAGTCACTAAAGTGCTGAAAA
TTGCCAACGACATTACCTTGATGCAAGACGCCCTTAAGAATAAAAATGCTGTGTTGACCGCTCTCGATAAGTCATTGGCA
GTGATTGAATTTACGCCCACTGGCATAGTGCTTTCGGCGAATCAGAATTTTCTCGACACTATGGGCTATAGCGAGCATGA
GATAGTCGGGAAACATCACAAACAATTTTGTGAAGCGGCTTATTATCGCGATAATCCTCATTTTTGGGCTTCATTATCCC
AAGGCAAGCATTTATCTGGGCGCTTTAAGCGCATTAACGGTCATGGACAGGTCGTGTGGTTAGAGGCGACCTATAATCCC
ATTTTTGATGAAAATGGCGCTGTCTATAAAGTGATTAAATTCGCCTCGGATATTACAGAGCGCGTCACTGCGGCGCTTAA
TGCCGTGGATCAGGCGGCCGTGACTTCAGAGCAAACCAGCCAAGTGACCAGTAACGCGGTGCAAATTTTAAATGATGCCG
TGCAAACATCCTGTGATATCGCCGCTAAGGTGAATAGTGCCACTCAGACGGGTGAGGAACTTAAAGCGCAGTCAAAGAAT
ATTACCGACATAGTCGTGACGATTCGCTCCATTGCCGACCAGACCAACTTATTGGCATTGAATGCGGCGATTGAGGCCGC
GCGTGCAGGGGATGCAGGACGAGGATTTTCTGTGGTGGCCGATGAAGTGCGTAAATTAGCGAATAACACCTCAGTTGCGA
CCACTGAAATCGCGCGCGTCGTCGAAACCAACCACATTCTTATCAATCAGATGGGCGACGTTCTAGGCTCAGTTTCGGGG
ATTGCCTTGCATGGTCAAGAGAGTATTAGTGAGGTATCGAGGGGCTTAAGTGAGATCACCCAAGGGGTAGCAAGGTTTGT
CGAAATGGTCGACACCATGAAGCCATAA

Upstream 100 bases:

>100_bases
TCGTTGTAACTGGCATGTCGTTATTGATGACACTTAATCTTTTCTTGCTTCTTGTAGCATCACACAAACAAGGACAGCTT
TTCTTATAAGGACTATTAAT

Downstream 100 bases:

>100_bases
TATGCTTCTTTAGCTCGCCGATTCACACAAATAGCTGATTTAGACCGATAGCTCAAACAAGATAGCTAACTCATACTGAT
ATCCATGTGCATTTAAGCAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLFTSKKRNSDIKMVDAEHFKYLTSIEDELNAVKANTAYISFSADGIILDANDLFLSAVGYTLADILGKHHRIFCDKSYT
LSSEYQQFWRDLAAGKSIRGTFLRFKQDKQPIYLEASYFPIVDGSGKVTKVLKIANDITLMQDALKNKNAVLTALDKSLA
VIEFTPTGIVLSANQNFLDTMGYSEHEIVGKHHKQFCEAAYYRDNPHFWASLSQGKHLSGRFKRINGHGQVVWLEATYNP
IFDENGAVYKVIKFASDITERVTAALNAVDQAAVTSEQTSQVTSNAVQILNDAVQTSCDIAAKVNSATQTGEELKAQSKN
ITDIVVTIRSIADQTNLLALNAAIEAARAGDAGRGFSVVADEVRKLANNTSVATTEIARVVETNHILINQMGDVLGSVSG
IALHGQESISEVSRGLSEITQGVARFVEMVDTMKP

Sequences:

>Translated_435_residues
MLFTSKKRNSDIKMVDAEHFKYLTSIEDELNAVKANTAYISFSADGIILDANDLFLSAVGYTLADILGKHHRIFCDKSYT
LSSEYQQFWRDLAAGKSIRGTFLRFKQDKQPIYLEASYFPIVDGSGKVTKVLKIANDITLMQDALKNKNAVLTALDKSLA
VIEFTPTGIVLSANQNFLDTMGYSEHEIVGKHHKQFCEAAYYRDNPHFWASLSQGKHLSGRFKRINGHGQVVWLEATYNP
IFDENGAVYKVIKFASDITERVTAALNAVDQAAVTSEQTSQVTSNAVQILNDAVQTSCDIAAKVNSATQTGEELKAQSKN
ITDIVVTIRSIADQTNLLALNAAIEAARAGDAGRGFSVVADEVRKLANNTSVATTEIARVVETNHILINQMGDVLGSVSG
IALHGQESISEVSRGLSEITQGVARFVEMVDTMKP
>Mature_435_residues
MLFTSKKRNSDIKMVDAEHFKYLTSIEDELNAVKANTAYISFSADGIILDANDLFLSAVGYTLADILGKHHRIFCDKSYT
LSSEYQQFWRDLAAGKSIRGTFLRFKQDKQPIYLEASYFPIVDGSGKVTKVLKIANDITLMQDALKNKNAVLTALDKSLA
VIEFTPTGIVLSANQNFLDTMGYSEHEIVGKHHKQFCEAAYYRDNPHFWASLSQGKHLSGRFKRINGHGQVVWLEATYNP
IFDENGAVYKVIKFASDITERVTAALNAVDQAAVTSEQTSQVTSNAVQILNDAVQTSCDIAAKVNSATQTGEELKAQSKN
ITDIVVTIRSIADQTNLLALNAAIEAARAGDAGRGFSVVADEVRKLANNTSVATTEIARVVETNHILINQMGDVLGSVSG
IALHGQESISEVSRGLSEITQGVARFVEMVDTMKP

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=192, Percent_Identity=32.8125, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788194, Length=212, Percent_Identity=32.0754716981132, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787690, Length=193, Percent_Identity=33.6787564766839, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367378, Length=131, Percent_Identity=39.6946564885496, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789453, Length=217, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 47611; Mature: 47611

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTSKKRNSDIKMVDAEHFKYLTSIEDELNAVKANTAYISFSADGIILDANDLFLSAVG
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHEEECEEEEEEECCEEEEECHHHHHHHHH
YTLADILGKHHRIFCDKSYTLSSEYQQFWRDLAAGKSIRGTFLRFKQDKQPIYLEASYFP
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCCEEEEEEEEE
IVDGSGKVTKVLKIANDITLMQDALKNKNAVLTALDKSLAVIEFTPTGIVLSANQNFLDT
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCEEEECCCCHHHH
MGYSEHEIVGKHHKQFCEAAYYRDNPHFWASLSQGKHLSGRFKRINGHGQVVWLEATYNP
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCCCEEEEEECCCC
IFDENGAVYKVIKFASDITERVTAALNAVDQAAVTSEQTSQVTSNAVQILNDAVQTSCDI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AAKVNSATQTGEELKAQSKNITDIVVTIRSIADQTNLLALNAAIEAARAGDAGRGFSVVA
HHHCCCHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHH
DEVRKLANNTSVATTEIARVVETNHILINQMGDVLGSVSGIALHGQESISEVSRGLSEIT
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHH
QGVARFVEMVDTMKP
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFTSKKRNSDIKMVDAEHFKYLTSIEDELNAVKANTAYISFSADGIILDANDLFLSAVG
CCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHEEECEEEEEEECCEEEEECHHHHHHHHH
YTLADILGKHHRIFCDKSYTLSSEYQQFWRDLAAGKSIRGTFLRFKQDKQPIYLEASYFP
HHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCCEEEEEEEEE
IVDGSGKVTKVLKIANDITLMQDALKNKNAVLTALDKSLAVIEFTPTGIVLSANQNFLDT
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCEEEECCCCHHHH
MGYSEHEIVGKHHKQFCEAAYYRDNPHFWASLSQGKHLSGRFKRINGHGQVVWLEATYNP
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEECCCCCEEEEEECCCC
IFDENGAVYKVIKFASDITERVTAALNAVDQAAVTSEQTSQVTSNAVQILNDAVQTSCDI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AAKVNSATQTGEELKAQSKNITDIVVTIRSIADQTNLLALNAAIEAARAGDAGRGFSVVA
HHHCCCHHHCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHH
DEVRKLANNTSVATTEIARVVETNHILINQMGDVLGSVSGIALHGQESISEVSRGLSEIT
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHH
QGVARFVEMVDTMKP
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]