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The map label for this gene is cobC [H]

Identifier: 126175564

GI number: 126175564

Start: 3933549

End: 3934268

Strand: Reverse

Name: cobC [H]

Synonym: Sbal_3367

Alternate gene names: 126175564

Gene position: 3934268-3933549 (Counterclockwise)

Preceding gene: 126175566

Following gene: 126175563

Centisome position: 76.73

GC content: 56.53

Gene sequence:

>720_bases
ATGAAACAAGTTCGATTGTTATTGTTACGCCACGGCGAGTGTGAAGGCGGCGCCATTTTACGCGGCCGTGTGGATGTGCC
TTTAAGCGAACAGGGTTGGCAGCAAATGTCGGCAGCGGTTGAGGCGCAGGCAAGTACCTGTAGCGCGATTTACAGTTCGA
CTTCACGCCGCTGCGGCGAATTTGCCCAAGCCTTTGCCGCCGAATTGCATTCGACGGCGGCGCTGGTATCTGAGTCAAGG
CCATTGCAGGCGCAGTTTTTGTCGGGTTTACAAGAAATCGACTTTGGCGATTGGGACGGTCGTCGGCTCGATGAGCTGTA
TCAGCAAGAGGGCGAAAGCTTAGCGGCCTATTGGCAAAACCCTTGGCAAACGCCGCCGCCCAATGGGGAAACTATGGCCA
GTTTCGAGTCGCGGGTGAATGGCGCCATTGACCAGATACTCGCCGTCGAGTTTGAACGATTGACAGTTGACTCACAAAAC
GCCGAGCTGGCTGTGGGATCGGGCGTGGCTGCGTGTGAACTGGCTGCCAAAGTATGGGTCGTGACCCACGGCGGAGTGAT
CCGTCACTTAATGGCGCGCGCCCTTGGGGTTGAACGGGCGGTGGGATTTTACAGTCAACTCGATTTACCCGTGGCGGCCG
TAGTGAGCATTAATGTGCTGCAAGATGAACACGGCGTTTGTTACTGGCGTTTAGATTGGCCGGGCGGACGCTGCGAGTGA

Upstream 100 bases:

>100_bases
GAGCTAGTTGTTGGGCTAAGGCGTAATTGAGTATATAGGACGACGGGTCTAATGTGGGCTTTCAACAAAATGTGCCACGA
GTGATAGACATAGGAATACG

Downstream 100 bases:

>100_bases
TCCGCGTTGCCCTAAGGTGAAGATTTTTCTTGTCTTACCAGCATGATTGTCGATTGCCTATTAAGGCAAATATAGGATAA
TGCTTTTTCCTGACGTTACC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKQVRLLLLRHGECEGGAILRGRVDVPLSEQGWQQMSAAVEAQASTCSAIYSSTSRRCGEFAQAFAAELHSTAALVSESR
PLQAQFLSGLQEIDFGDWDGRRLDELYQQEGESLAAYWQNPWQTPPPNGETMASFESRVNGAIDQILAVEFERLTVDSQN
AELAVGSGVAACELAAKVWVVTHGGVIRHLMARALGVERAVGFYSQLDLPVAAVVSINVLQDEHGVCYWRLDWPGGRCE

Sequences:

>Translated_239_residues
MKQVRLLLLRHGECEGGAILRGRVDVPLSEQGWQQMSAAVEAQASTCSAIYSSTSRRCGEFAQAFAAELHSTAALVSESR
PLQAQFLSGLQEIDFGDWDGRRLDELYQQEGESLAAYWQNPWQTPPPNGETMASFESRVNGAIDQILAVEFERLTVDSQN
AELAVGSGVAACELAAKVWVVTHGGVIRHLMARALGVERAVGFYSQLDLPVAAVVSINVLQDEHGVCYWRLDWPGGRCE
>Mature_239_residues
MKQVRLLLLRHGECEGGAILRGRVDVPLSEQGWQQMSAAVEAQASTCSAIYSSTSRRCGEFAQAFAAELHSTAALVSESR
PLQAQFLSGLQEIDFGDWDGRRLDELYQQEGESLAAYWQNPWQTPPPNGETMASFESRVNGAIDQILAVEFERLTVDSQN
AELAVGSGVAACELAAKVWVVTHGGVIRHLMARALGVERAVGFYSQLDLPVAAVVSINVLQDEHGVCYWRLDWPGGRCE

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=218, Percent_Identity=28.8990825688073, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 26136; Mature: 26136

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVRLLLLRHGECEGGAILRGRVDVPLSEQGWQQMSAAVEAQASTCSAIYSSTSRRCGE
CCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAQAFAAELHSTAALVSESRPLQAQFLSGLQEIDFGDWDGRRLDELYQQEGESLAAYWQN
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCEEHHHCC
PWQTPPPNGETMASFESRVNGAIDQILAVEFERLTVDSQNAELAVGSGVAACELAAKVWV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCHHHHHHHHEEEE
VTHGGVIRHLMARALGVERAVGFYSQLDLPVAAVVSINVLQDEHGVCYWRLDWPGGRCE
EECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKQVRLLLLRHGECEGGAILRGRVDVPLSEQGWQQMSAAVEAQASTCSAIYSSTSRRCGE
CCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAQAFAAELHSTAALVSESRPLQAQFLSGLQEIDFGDWDGRRLDELYQQEGESLAAYWQN
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCEEHHHCC
PWQTPPPNGETMASFESRVNGAIDQILAVEFERLTVDSQNAELAVGSGVAACELAAKVWV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCHHHHHHHHEEEE
VTHGGVIRHLMARALGVERAVGFYSQLDLPVAAVVSINVLQDEHGVCYWRLDWPGGRCE
EECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]