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The map label for this gene is rpiA

Identifier: 126175493

GI number: 126175493

Start: 3855222

End: 3855884

Strand: Direct

Name: rpiA

Synonym: Sbal_3293

Alternate gene names: 126175493

Gene position: 3855222-3855884 (Clockwise)

Preceding gene: 126175489

Following gene: 126175495

Centisome position: 75.19

GC content: 47.06

Gene sequence:

>663_bases
ATGACTCAAGATGAAATGAAAAAAGCTGCCGGTTGGGCCGCACTCAAGTACGTTGAAAGAGACAGTATTGTTGGTGTTGG
TACTGGTTCGACTGTGAATCACTTTATTGATGCACTGGCGACCATGAAAGCTGATATCGAAGGCGCAGTCTCTAGTTCTG
AGGCATCAACTCAGAAAATGAAAGCGCTGGGTATTCCCGTTTATGACTTAAACAGCGTCGATCGTTTATCTGTCTATGTG
GACGGTGCCGATGAAATCAACGACCGTATGGATATGATCAAAGGGGGCGGCGCGGCGTTAACTCGCGAGAAAATTGTTGC
GGCTGTGGCTGAAAAATTTATCTGTATCGTGGATAACACTAAGCAAGTCGACATCCTAGGGGAATTCCCACTGCCAGTTG
AAGTCATTCCTATGGCGCGCTCTTATGTGGCACGTCAGTTAGTTAAGCTAGGCGGCGATCCTGTGTACCGTGAAGGCGTT
GTGACCGATAACGGCAACGTGATCCTCGATGTGTACAATCTTAAGATCCTTAATCCAAAAGAATTGGAAAGTCAGATCAA
TGAGATAGTCGGTGTCGTCACTAACGGTCTGTTCGCTAAACGCGGCGCAGATGTGTTGTTAGTCGGTACACCTGATGGCG
TAAAAACCTTTACCGCCGAATAA

Upstream 100 bases:

>100_bases
TCTAGATCACACCTAAGGCTGAATTGCGCCACATTATTTATCGGAAAAGAGTATACTAAGCGCAGAATTTTTTACTCATT
TGCCGTTACAGGATGTCAAC

Downstream 100 bases:

>100_bases
GTTAAGCGTTAACACTTACATCCCAGTCACAAGGCTGCAGATGTAAAAACACGGTTAAAATACGCGACAAAAATGCCAGC
CACTTTATTCAAGGGCTGGC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTQDEMKKAAGWAALKYVERDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYV
DGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGV
VTDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAE

Sequences:

>Translated_220_residues
MTQDEMKKAAGWAALKYVERDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYV
DGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGV
VTDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAE
>Mature_219_residues
TQDEMKKAAGWAALKYVERDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYVD
GADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVV
TDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=225, Percent_Identity=36.8888888888889, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=76.036866359447, Blast_Score=337, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=35.2380952380952, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=240, Percent_Identity=30.4166666666667, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281364072, Length=202, Percent_Identity=34.1584158415842, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_SHEB2 (B8E4U3)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002357002.1
- ProteinModelPortal:   B8E4U3
- SMR:   B8E4U3
- GeneID:   7087837
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_1064
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23590; Mature: 23459

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALKYVERDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKM
CCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KALGIPVYDLNSVDRLSVYVDGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNT
HHHCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCC
KQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVVTDNGNVILDVYNLKILNPK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEEEEEECHH
ELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAE
HHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCEEECCC
>Mature Secondary Structure 
TQDEMKKAAGWAALKYVERDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKM
CHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KALGIPVYDLNSVDRLSVYVDGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNT
HHHCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEECCC
KQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVVTDNGNVILDVYNLKILNPK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEEEEEECHH
ELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAE
HHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA