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The map label for this gene is corC [H]

Identifier: 126175464

GI number: 126175464

Start: 3826044

End: 3826919

Strand: Direct

Name: corC [H]

Synonym: Sbal_3264

Alternate gene names: 126175464

Gene position: 3826044-3826919 (Clockwise)

Preceding gene: 126175463

Following gene: 126175465

Centisome position: 74.62

GC content: 46.12

Gene sequence:

>876_bases
ATGAGTGACGATATCCCCCCGAGTACGAACGCCCACAAGAAAGGTTGGTTTGATAGAGTAAGTCAGCTATTTCAGGGCGA
ACCTCAAAATCGCGAAGATTTAGTCGATGTGATTGATGGTGCAGAACAGCGCGATCTGATCACTCAAGACACCCGCGAGA
TGATAAAAGGTGTATTAGACGTTTCTGATATGCGTGTTCGGGATATAATGATCCCAAGAGCTCAAATTGTCGCCCTCCAG
ATAGACAACTCGGTCGAAGAATTACTCGCCACAGTGATTGGTTCAGGTCACTCGCGCTTCCCCGTCGTTAACGAAGATAA
AGACCATATCGAAGGCATTTTGCTTGCTAAAGATTTGATCCCTTACGGTTTCTCCAACAGTGATGAGCCCTTCTCGCTGG
ATCGGGTGATCCGTCCTGCTGTGGTTGTACCCGAAAGCAAACGCGTCGATGTATTGCTAAAAGAATTCCGCTCACAACGA
TACCATATGGCGATTGTGGTCGATGAATACGGCGGCGTGTCAGGTCTGGTGACTATCGAAGATATTTTGGAAGAAATTGT
CGGTGAGATTGAAGACGAATTCGACCACGATAGCACGGAAGAAACTGAGATCCGCAAAGTCGGCAACACGGTTTATATGG
TTAAGGCCTTGACGCCAATCGAAGATTTCAACGAAGAATTCAACACTGAATTCAGCGATGAAGAGTTTGATACTGTCGGT
GGCTTAGTCTCACACGCCTTTGGTCATCTGCCAGAACGCAACGAGAGCATCATCATTGAAGGCATTGAATTTAAAGTTAT
CAATGCTGACACAAGGCGTTTAATCCAACTCAGAGTTAAACTCCCCGATCCTAATACTGGCGAAGACGTAGAATAA

Upstream 100 bases:

>100_bases
TCGTTAGAGACCCAACTCATTGAAGGCTTAGGCTTTACTGACCCATATAAGGAACAATAGTTAGCTAAGATAATCCCTAT
CAAAAGCTAATGAGAAAACT

Downstream 100 bases:

>100_bases
TCACTCGTGCTAAAACAAATCCGGGCTTTTGCCCAACAAAAGTCCCGACCTAGTGCTTTGAGACTCGTACTGGCATTTGC
CCTTGGCGCCAGTACGGCGC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSDDIPPSTNAHKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRDLITQDTREMIKGVLDVSDMRVRDIMIPRAQIVALQ
IDNSVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSDEPFSLDRVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSTEETEIRKVGNTVYMVKALTPIEDFNEEFNTEFSDEEFDTVG
GLVSHAFGHLPERNESIIIEGIEFKVINADTRRLIQLRVKLPDPNTGEDVE

Sequences:

>Translated_291_residues
MSDDIPPSTNAHKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRDLITQDTREMIKGVLDVSDMRVRDIMIPRAQIVALQ
IDNSVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSDEPFSLDRVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSTEETEIRKVGNTVYMVKALTPIEDFNEEFNTEFSDEEFDTVG
GLVSHAFGHLPERNESIIIEGIEFKVINADTRRLIQLRVKLPDPNTGEDVE
>Mature_290_residues
SDDIPPSTNAHKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRDLITQDTREMIKGVLDVSDMRVRDIMIPRAQIVALQI
DNSVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLIPYGFSNSDEPFSLDRVIRPAVVVPESKRVDVLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSTEETEIRKVGNTVYMVKALTPIEDFNEEFNTEFSDEEFDTVGG
LVSHAFGHLPERNESIIIEGIEFKVINADTRRLIQLRVKLPDPNTGEDVE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=210, Percent_Identity=35.2380952380952, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI94681046, Length=180, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40068053, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI40068055, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786879, Length=286, Percent_Identity=60.1398601398601, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI1790664, Length=272, Percent_Identity=25, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693175, Length=213, Percent_Identity=27.6995305164319, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788119, Length=244, Percent_Identity=32.3770491803279, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082033, Length=239, Percent_Identity=26.3598326359833, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324512, Length=159, Percent_Identity=32.7044025157233, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32904; Mature: 32773

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDIPPSTNAHKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRDLITQDTREMIKGVLD
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
VSDMRVRDIMIPRAQIVALQIDNSVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLI
CCCCHHHHEECCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
PYGFSNSDEPFSLDRVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
CCCCCCCCCCCCHHHHHCCEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSTEETEIRKVGNTVYMVKALTPIEDFNEEFNTEFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHH
GLVSHAFGHLPERNESIIIEGIEFKVINADTRRLIQLRVKLPDPNTGEDVE
HHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SDDIPPSTNAHKKGWFDRVSQLFQGEPQNREDLVDVIDGAEQRDLITQDTREMIKGVLD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
VSDMRVRDIMIPRAQIVALQIDNSVEELLATVIGSGHSRFPVVNEDKDHIEGILLAKDLI
CCCCHHHHEECCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
PYGFSNSDEPFSLDRVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
CCCCCCCCCCCCHHHHHCCEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSTEETEIRKVGNTVYMVKALTPIEDFNEEFNTEFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHH
GLVSHAFGHLPERNESIIIEGIEFKVINADTRRLIQLRVKLPDPNTGEDVE
HHHHHHHHCCCCCCCEEEEEEEEEEEECCCHHEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]