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The map label for this gene is ribD [H]

Identifier: 126175361

GI number: 126175361

Start: 3698746

End: 3699900

Strand: Reverse

Name: ribD [H]

Synonym: Sbal_3160

Alternate gene names: 126175361

Gene position: 3699900-3698746 (Counterclockwise)

Preceding gene: 126175362

Following gene: 126175360

Centisome position: 72.16

GC content: 51.08

Gene sequence:

>1155_bases
ATGAGCTTGAACATAAGTTGGTCCGTACTCGATACCCAAATGATGAGCCGCGCGATTCAATTGGCGCGCAAAGGTTTTTA
TACCACCAGACCCAATCCCAGTGTGGGCTGCGTTATTGTTAAAGATAATCAGATCGTCGGCGAAGGTTATCATCAAAAAG
CGGGTGAGCCCCACGCCGAAGTGCATGCGCTACGCATGGCTGGCGAACACGCCCGTGGCGCAACGGCCTATGTCACCTTA
GAGCCATGCAGCCATTATGGCCGCACGCCGCCCTGCGCCTTGGCGCTGATCAATATTGGCGTTAAACGTGTGGTGGTAGC
GGTTGAAGATCCTAATCCGCAAGTGGCTGGTCGCGGTATTCAAATGCTGCGCGACGCCGGTATTGAAGTGGATGTGGGGT
TACACCGCGATGAAGCTTATGCCTTGAATTTAGGCTTTATGAAGCGGATGGAATCAGGTTTACCCAGAGTTACAGTCAAA
TTAGCTGCGAGTCTCGATGGTAAAACCGCGCTGTCTAACGGTGTGTCTAAATGGATTACTGGGCCTGAATCTCGCCGCGA
CGTGCAGCGCTTACGCTTACGTTCCTGCGCGTTGGTGACAGGGATTGAAACCATACTGGTGGACGATCCCTCGCTCAATG
TGCGATATCAAGAACTTGGCGGCATAAAAGACAGCGTAACCGAAGCGCAATTACTGCAGCCATTAAGAGTCATACTCGAC
AGTCGCGCCCGTTTGCCGTTATCGGCTGCCTGTTTGGCTGTCGTATCGCCGATACTCTTGGTCTCGACCGTGGCTTATCC
CGCAAAGTTTCAAGCACAATTGCCCTCCCATGTGAGTTGCCTCGTGTTACCTGCGATTGCAGGTCGCGTATCCTTACCTG
AACTATTAAGCTATTTAGGCCAAAGCTGTAATCACGTGCTAGTGGAAGCGGGTGCAACCTTAGCGGGCGCTTTTTTAGCG
CAGGGGCTGGCCGATGAATTAGTGCTGTACCAAGCGATGAAAATCCTCGGTGGGCAAGGGCGTAATCTATTGCAGCTACC
CGATTATCAAACCATGGCGCAAATTCCTGCATTAATGTTGGTCGATGAGCGCAAATTAGGGCCAGATACCCGTTTAATCT
TGAGCGTTATGCTTGATACTTCTTTAATTAATTAA

Upstream 100 bases:

>100_bases
CTTTAAAAGAGGCTTTTGATTAATAGCTTCTGCAAGACAGGTTTTAAACACAGATTTACAAGACTGGTGAAAGCCGAAAC
CTTTAACAACAGGGTTGAAC

Downstream 100 bases:

>100_bases
GTGAGTTAACCATGTTTACTGGGATTATTGAAGCCGTTGGCACCCTGCGCAAACTGGAGCGTAAAGGCGATGATATTCGT
CTTACCGTGGCGAGCGGCAA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPSVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTL
EPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVAGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVK
LAASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILVDDPSLNVRYQELGGIKDSVTEAQLLQPLRVILD
SRARLPLSAACLAVVSPILLVSTVAYPAKFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLA
QGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALMLVDERKLGPDTRLILSVMLDTSLIN

Sequences:

>Translated_384_residues
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPSVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTL
EPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVAGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVK
LAASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILVDDPSLNVRYQELGGIKDSVTEAQLLQPLRVILD
SRARLPLSAACLAVVSPILLVSTVAYPAKFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLA
QGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALMLVDERKLGPDTRLILSVMLDTSLIN
>Mature_383_residues
SLNISWSVLDTQMMSRAIQLARKGFYTTRPNPSVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTLE
PCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVAGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKL
AASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILVDDPSLNVRYQELGGIKDSVTEAQLLQPLRVILDS
RARLPLSAACLAVVSPILLVSTVAYPAKFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLAQ
GLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALMLVDERKLGPDTRLILSVMLDTSLIN

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=51.4905149051491, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI145693172, Length=152, Percent_Identity=35.5263157894737, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41406; Mature: 41275

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPSVGCVIVKDNQIVGEGYHQKAGEPHAE
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCHHCCCCCHHH
VHALRMAGEHARGATAYVTLEPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVAGRGI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHH
QMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKLAASLDGKTALSNGVSKWIT
HHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCHHHHCC
GPESRRDVQRLRLRSCALVTGIETILVDDPSLNVRYQELGGIKDSVTEAQLLQPLRVILD
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHC
SRARLPLSAACLAVVSPILLVSTVAYPAKFQAQLPSHVSCLVLPAIAGRVSLPELLSYLG
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QSCNHVLVEAGATLAGAFLAQGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALML
HCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEEE
VDERKLGPDTRLILSVMLDTSLIN
EECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLNISWSVLDTQMMSRAIQLARKGFYTTRPNPSVGCVIVKDNQIVGEGYHQKAGEPHAE
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCHHCCCCCHHH
VHALRMAGEHARGATAYVTLEPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVAGRGI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHH
QMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKLAASLDGKTALSNGVSKWIT
HHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCHHHHCC
GPESRRDVQRLRLRSCALVTGIETILVDDPSLNVRYQELGGIKDSVTEAQLLQPLRVILD
CCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHC
SRARLPLSAACLAVVSPILLVSTVAYPAKFQAQLPSHVSCLVLPAIAGRVSLPELLSYLG
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QSCNHVLVEAGATLAGAFLAQGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALML
HCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEEE
VDERKLGPDTRLILSVMLDTSLIN
EECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]