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The map label for this gene is capD [H]

Identifier: 126175079

GI number: 126175079

Start: 3387765

End: 3389705

Strand: Reverse

Name: capD [H]

Synonym: Sbal_2876

Alternate gene names: 126175079

Gene position: 3389705-3387765 (Counterclockwise)

Preceding gene: 126175080

Following gene: 126175076

Centisome position: 66.11

GC content: 41.94

Gene sequence:

>1941_bases
ATGGAATTTTTGCAGTGTTTATTTTCTTTAAAGCGGGCACAGAAGCGTCTAGTGAGTGTCGCGATTGATTCGGTATTTCT
CTTAGTCGCATTTTGGGCTGCTTTGTTGGTACGTTTGGATGCCGTAAGCGTATTTACTAATAGCGTATACTGGTTGCTCA
TTGTTTTGGTTGTGCCTGTGAGTATCATGGTGTTTGCTAAGCTGGGATTGTATCGTGCTGTGCTTAGATATATGGGATTG
CAGGCGCTAACTGCGATTATTGTTGGGGTTCTTGCATCAACAGTGTCGTTAGTGTTAATTGCGTATTACAGTGAGGCGAA
TTTACCCCGTACGGTACCAATTATTTACGCAGCTTTTGCCTTGGTATTTGTCGGTGGAACTCGCGCTATGGTGCGCTCGT
TAGTAGGGTCTGGTCTAAAGCGGGTTGGCGAACCTGTGATTATTTATGGGGCAGGGGTCAGCGGACGGCAGTTAGTGACC
TCATTGGTCCAGAGTCATGAATATTATCCTTTTGCATTTGTTGATGATGATGTGACTTTACATGGCACTGTCATCCAAGG
AGTGCATGTTCATTCGCCTTCTATTATTAAAAAACTCATCACACAAAAAGCAGCTACTAAAGTGTTGCTGGCTATGCCAA
GTGCTTCTCGCTCTCGTCGCCAAGAGATTTTAGTTAAGCTCGAACCTTTGGCTGTACAAGTTTTAACCTTACCTGCAATG
GCTGATCTGGTAAGTGGTAATAAGCTTTATAGCGATATTAAAGAAGTCGAAATCGATGATTTGTTAGGACGTGATGCAGT
TACTCCCCGTTGCGACTTAATGGTCGCCAATATCCGCAACAAAGTAGTGATGGTCACGGGAGCTGGCGGCTCGATTGGTT
CTGAGTTATGTCGACAGATATTAAAACAATCACCTAAAAAATTAGTGTTATTTGAATTATCTGAGTTTGCCTTGTATACG
ATTGATCGTGAACTTTCTGCGACAGCTTTTGAGTTAGGGCTTGATGTTAAGATTTTACCAATTATGGGTTCGGTACAACG
GGAAAATCGTGTTCAAGCAGTAATGCAATCTTTTAGAGTGCAAACTGTGTATCACGCTGCAGCTTATAAGCATGTGCCAT
TGGTGGAGCACAATGTCGTTGAAGGTGTGCGTAATAATATATTTGGTACTTTATATACTGCACGCGCAGCTATTGCAGCT
AAGGTTGAAACTTTTGTATTGATTTCGACGGATAAAGCTGTACGACCTACTAATATCATGGGCACTACTAAGCGTATGGC
CGAGTTGGCACTTCAAGCGTTATCTAAAGAAACACATCAAACCCGTTTTAGCATGGTTCGCTTTGGTAATGTTTTGGGCT
CTTCAGGTTCTGTAGTGCCATTATTCCGAAAGCAAATTGCTAATGGCGGCCCTGTTACTGTTACGCATCGTGACATAACT
CGTTTCTTTATGACCATTCCTGAGGCTTCACAGTTGGTTATCCAAGCGGGGGCAATGGGCAAAGGTGGCGATGTGTTCGT
GCTTGACATGGGTAAAGCAGTTAAAATTGTTGATTTAGCTGCAAAAATGATTCGCCTTAGCGGTTTTGAAGTAAAGGATG
AACTCAATCCCGATGGTGATATTGCCATCGAGTTTAGTGGCTTACGTCCTGGTGAAAAATTATACGAAGAATTACTGATT
GGTGATGATGTTACTGGCACCGAACATGAGCGTATTATGACAGCCAACGAAATTTTTCTTTCTTGGAAAGAGTTAGAATG
TATTCTTAATCGCTTAGATAAAGCTTGTCATGAGTTTAATCATGAAGCTATACGAGAAATCTTACTGTCTGCACCAACAG
GTTTTAATCCAACAGACGGGATATGCGATTTAGTGTGGCAACAAAAGAAAAAATTAAGCGCTGTTGATGGCCAAAATAAA
GTTGTTCCATTAGTTTCTTAG

Upstream 100 bases:

>100_bases
ATTCTCGCTTTCTGTTATTGAGCCTCTTGTGCTGTGGGGCTGTTGGTAAATGATGGTTCCTATGAAGTTTTTAAATAAGT
TGAGTAAGTTGGAGCTGAAA

Downstream 100 bases:

>100_bases
TTTTCTTGTGGTATTTGAAAAGCCAAATCAATTTGATTTGGCTTTTTCGTTTTTAGGTTTTTAAGGATGTGGTATGTCTC
GTAAATATTTTGGTACTGAC

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MEFLQCLFSLKRAQKRLVSVAIDSVFLLVAFWAALLVRLDAVSVFTNSVYWLLIVLVVPVSIMVFAKLGLYRAVLRYMGL
QALTAIIVGVLASTVSLVLIAYYSEANLPRTVPIIYAAFALVFVGGTRAMVRSLVGSGLKRVGEPVIIYGAGVSGRQLVT
SLVQSHEYYPFAFVDDDVTLHGTVIQGVHVHSPSIIKKLITQKAATKVLLAMPSASRSRRQEILVKLEPLAVQVLTLPAM
ADLVSGNKLYSDIKEVEIDDLLGRDAVTPRCDLMVANIRNKVVMVTGAGGSIGSELCRQILKQSPKKLVLFELSEFALYT
IDRELSATAFELGLDVKILPIMGSVQRENRVQAVMQSFRVQTVYHAAAYKHVPLVEHNVVEGVRNNIFGTLYTARAAIAA
KVETFVLISTDKAVRPTNIMGTTKRMAELALQALSKETHQTRFSMVRFGNVLGSSGSVVPLFRKQIANGGPVTVTHRDIT
RFFMTIPEASQLVIQAGAMGKGGDVFVLDMGKAVKIVDLAAKMIRLSGFEVKDELNPDGDIAIEFSGLRPGEKLYEELLI
GDDVTGTEHERIMTANEIFLSWKELECILNRLDKACHEFNHEAIREILLSAPTGFNPTDGICDLVWQQKKKLSAVDGQNK
VVPLVS

Sequences:

>Translated_646_residues
MEFLQCLFSLKRAQKRLVSVAIDSVFLLVAFWAALLVRLDAVSVFTNSVYWLLIVLVVPVSIMVFAKLGLYRAVLRYMGL
QALTAIIVGVLASTVSLVLIAYYSEANLPRTVPIIYAAFALVFVGGTRAMVRSLVGSGLKRVGEPVIIYGAGVSGRQLVT
SLVQSHEYYPFAFVDDDVTLHGTVIQGVHVHSPSIIKKLITQKAATKVLLAMPSASRSRRQEILVKLEPLAVQVLTLPAM
ADLVSGNKLYSDIKEVEIDDLLGRDAVTPRCDLMVANIRNKVVMVTGAGGSIGSELCRQILKQSPKKLVLFELSEFALYT
IDRELSATAFELGLDVKILPIMGSVQRENRVQAVMQSFRVQTVYHAAAYKHVPLVEHNVVEGVRNNIFGTLYTARAAIAA
KVETFVLISTDKAVRPTNIMGTTKRMAELALQALSKETHQTRFSMVRFGNVLGSSGSVVPLFRKQIANGGPVTVTHRDIT
RFFMTIPEASQLVIQAGAMGKGGDVFVLDMGKAVKIVDLAAKMIRLSGFEVKDELNPDGDIAIEFSGLRPGEKLYEELLI
GDDVTGTEHERIMTANEIFLSWKELECILNRLDKACHEFNHEAIREILLSAPTGFNPTDGICDLVWQQKKKLSAVDGQNK
VVPLVS
>Mature_646_residues
MEFLQCLFSLKRAQKRLVSVAIDSVFLLVAFWAALLVRLDAVSVFTNSVYWLLIVLVVPVSIMVFAKLGLYRAVLRYMGL
QALTAIIVGVLASTVSLVLIAYYSEANLPRTVPIIYAAFALVFVGGTRAMVRSLVGSGLKRVGEPVIIYGAGVSGRQLVT
SLVQSHEYYPFAFVDDDVTLHGTVIQGVHVHSPSIIKKLITQKAATKVLLAMPSASRSRRQEILVKLEPLAVQVLTLPAM
ADLVSGNKLYSDIKEVEIDDLLGRDAVTPRCDLMVANIRNKVVMVTGAGGSIGSELCRQILKQSPKKLVLFELSEFALYT
IDRELSATAFELGLDVKILPIMGSVQRENRVQAVMQSFRVQTVYHAAAYKHVPLVEHNVVEGVRNNIFGTLYTARAAIAA
KVETFVLISTDKAVRPTNIMGTTKRMAELALQALSKETHQTRFSMVRFGNVLGSSGSVVPLFRKQIANGGPVTVTHRDIT
RFFMTIPEASQLVIQAGAMGKGGDVFVLDMGKAVKIVDLAAKMIRLSGFEVKDELNPDGDIAIEFSGLRPGEKLYEELLI
GDDVTGTEHERIMTANEIFLSWKELECILNRLDKACHEFNHEAIREILLSAPTGFNPTDGICDLVWQQKKKLSAVDGQNK
VVPLVS

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 70840; Mature: 70840

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLQCLFSLKRAQKRLVSVAIDSVFLLVAFWAALLVRLDAVSVFTNSVYWLLIVLVVPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIMVFAKLGLYRAVLRYMGLQALTAIIVGVLASTVSLVLIAYYSEANLPRTVPIIYAAFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVFVGGTRAMVRSLVGSGLKRVGEPVIIYGAGVSGRQLVTSLVQSHEYYPFAFVDDDVTL
HHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCEEE
HGTVIQGVHVHSPSIIKKLITQKAATKVLLAMPSASRSRRQEILVKLEPLAVQVLTLPAM
EEEEEECEEECCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHEEECCHHEEEHHHHHH
ADLVSGNKLYSDIKEVEIDDLLGRDAVTPRCDLMVANIRNKVVMVTGAGGSIGSELCRQI
HHHHCCHHHHHHHHHCCHHHHHCCCCCCCCHHEEEEECCCCEEEEECCCCCHHHHHHHHH
LKQSPKKLVLFELSEFALYTIDRELSATAFELGLDVKILPIMGSVQRENRVQAVMQSFRV
HHCCCCEEEEEEHHHHHEEEECCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
QTVYHAAAYKHVPLVEHNVVEGVRNNIFGTLYTARAAIAAKVETFVLISTDKAVRPTNIM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCC
GTTKRMAELALQALSKETHQTRFSMVRFGNVLGSSGSVVPLFRKQIANGGPVTVTHRDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHH
RFFMTIPEASQLVIQAGAMGKGGDVFVLDMGKAVKIVDLAAKMIRLSGFEVKDELNPDGD
HHHHHCCCHHHHHEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
IAIEFSGLRPGEKLYEELLIGDDVTGTEHERIMTANEIFLSWKELECILNRLDKACHEFN
EEEEECCCCCHHHHHHHHHCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
HEAIREILLSAPTGFNPTDGICDLVWQQKKKLSAVDGQNKVVPLVS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCC
>Mature Secondary Structure
MEFLQCLFSLKRAQKRLVSVAIDSVFLLVAFWAALLVRLDAVSVFTNSVYWLLIVLVVPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIMVFAKLGLYRAVLRYMGLQALTAIIVGVLASTVSLVLIAYYSEANLPRTVPIIYAAFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVFVGGTRAMVRSLVGSGLKRVGEPVIIYGAGVSGRQLVTSLVQSHEYYPFAFVDDDVTL
HHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCEEE
HGTVIQGVHVHSPSIIKKLITQKAATKVLLAMPSASRSRRQEILVKLEPLAVQVLTLPAM
EEEEEECEEECCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHEEECCHHEEEHHHHHH
ADLVSGNKLYSDIKEVEIDDLLGRDAVTPRCDLMVANIRNKVVMVTGAGGSIGSELCRQI
HHHHCCHHHHHHHHHCCHHHHHCCCCCCCCHHEEEEECCCCEEEEECCCCCHHHHHHHHH
LKQSPKKLVLFELSEFALYTIDRELSATAFELGLDVKILPIMGSVQRENRVQAVMQSFRV
HHCCCCEEEEEEHHHHHEEEECCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
QTVYHAAAYKHVPLVEHNVVEGVRNNIFGTLYTARAAIAAKVETFVLISTDKAVRPTNIM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCC
GTTKRMAELALQALSKETHQTRFSMVRFGNVLGSSGSVVPLFRKQIANGGPVTVTHRDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHH
RFFMTIPEASQLVIQAGAMGKGGDVFVLDMGKAVKIVDLAAKMIRLSGFEVKDELNPDGD
HHHHHCCCHHHHHEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
IAIEFSGLRPGEKLYEELLIGDDVTGTEHERIMTANEIFLSWKELECILNRLDKACHEFN
EEEEECCCCCHHHHHHHHHCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
HEAIREILLSAPTGFNPTDGICDLVWQQKKKLSAVDGQNKVVPLVS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]