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The map label for this gene is cat [H]

Identifier: 126175059

GI number: 126175059

Start: 3363390

End: 3364028

Strand: Direct

Name: cat [H]

Synonym: Sbal_2855

Alternate gene names: 126175059

Gene position: 3363390-3364028 (Clockwise)

Preceding gene: 126175058

Following gene: 126175060

Centisome position: 65.6

GC content: 51.02

Gene sequence:

>639_bases
ATGTCTGCGCCTAGATCAGAGCCGGCATCTTTGCCTGATTATCAAAGCCAGCATAAAAAGCGTCTATCATGGATGCCGTG
GCTGTATTTTTCTTTAAAAGAGAAACATTTAGTCTGGGCAAAACCTTGGCAGGATGAGATCCAAGCAAAGCTTTGCGCCC
TCGAAACAGTCAACATCGGCGAGCACTGTTTTATCGCCCCCGAAGCACAGTTATTTGCCGAACCCAATCGAGATATCCGC
ATGGGTAATCGCTGCATGATCGCCGCCGACTGTTTTTTACACGGGCCCATCACGCTAGGGGATGAAGTGGCGATTAATCA
TGGTTGCTCCTTCGATGGCGGCAGGGTCGGGATTCAGATAGGCAATCAAACCCGCATCGCCAATAATGTCACCCTTTACG
CCTTCAACCATGGCATGGCGCCAGATACGCCCATCTATCAACAAGCTGCCAACTCCAAAGGCATTGTTATAGGTAAAGAT
GTGTGGATTGGCGCTCAGGCCGGCATAGTCGATGGTGTGACAATTGGCGATCACGCTGTGGTGGGTATGGGCAGCATAGT
GACGAAAGATGTGCCCGACTGGGCGATAGTGGCAGGCAACCCCGCCAAAGTGATTGGCGATAGGCGTGATAAAAGCTAA

Upstream 100 bases:

>100_bases
CGCCCTCTATGATTTAGATGTGTTCTGGCAAATGGCGGTCGATAATAATGACCAAGAATACATCTTGGTACTGGAACTCA
AACCGGGGAAATGTGGCTAA

Downstream 100 bases:

>100_bases
ATCGGCCAGTACAAATCGCGTCTTAAATCGCTTTCCTTTAGCTCAGTAATCTTCTCAAAAATGCTATTTGTCTCCCAGCT
AGTTGAATTTAACCTAAATA

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSAPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRDIR
MGNRCMIAADCFLHGPITLGDEVAINHGCSFDGGRVGIQIGNQTRIANNVTLYAFNHGMAPDTPIYQQAANSKGIVIGKD
VWIGAQAGIVDGVTIGDHAVVGMGSIVTKDVPDWAIVAGNPAKVIGDRRDKS

Sequences:

>Translated_212_residues
MSAPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRDIR
MGNRCMIAADCFLHGPITLGDEVAINHGCSFDGGRVGIQIGNQTRIANNVTLYAFNHGMAPDTPIYQQAANSKGIVIGKD
VWIGAQAGIVDGVTIGDHAVVGMGSIVTKDVPDWAIVAGNPAKVIGDRRDKS
>Mature_211_residues
SAPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIGEHCFIAPEAQLFAEPNRDIRM
GNRCMIAADCFLHGPITLGDEVAINHGCSFDGGRVGIQIGNQTRIANNVTLYAFNHGMAPDTPIYQQAANSKGIVIGKDV
WIGAQAGIVDGVTIGDHAVVGMGSIVTKDVPDWAIVAGNPAKVIGDRRDKS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=90, Percent_Identity=44.4444444444444, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786537, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788345, Length=154, Percent_Identity=30.5194805194805, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322243, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23147; Mature: 23015

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIG
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEEEEECCC
EHCFIAPEAQLFAEPNRDIRMGNRCMIAADCFLHGPITLGDEVAINHGCSFDGGRVGIQI
CEEEECCCHHEEECCCCCEECCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEE
GNQTRIANNVTLYAFNHGMAPDTPIYQQAANSKGIVIGKDVWIGAQAGIVDGVTIGDHAV
CCCEEEECCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEECCCCCCCCEEECCCEE
VGMGSIVTKDVPDWAIVAGNPAKVIGDRRDKS
EECCCCEECCCCCEEEEECCCHHEECCCCCCC
>Mature Secondary Structure 
SAPRSEPASLPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDEIQAKLCALETVNIG
CCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHHHEEEEECCC
EHCFIAPEAQLFAEPNRDIRMGNRCMIAADCFLHGPITLGDEVAINHGCSFDGGRVGIQI
CEEEECCCHHEEECCCCCEECCCEEEEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEEE
GNQTRIANNVTLYAFNHGMAPDTPIYQQAANSKGIVIGKDVWIGAQAGIVDGVTIGDHAV
CCCEEEECCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCEEEECCCCCCCCEEECCCEE
VGMGSIVTKDVPDWAIVAGNPAKVIGDRRDKS
EECCCCEECCCCCEEEEECCCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]