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The map label for this gene is yliI [H]

Identifier: 126175044

GI number: 126175044

Start: 3339408

End: 3340601

Strand: Direct

Name: yliI [H]

Synonym: Sbal_2839

Alternate gene names: 126175044

Gene position: 3339408-3340601 (Clockwise)

Preceding gene: 126175043

Following gene: 126175048

Centisome position: 65.13

GC content: 47.82

Gene sequence:

>1194_bases
ATGAAACGGATCACCTTTAAACTAAGCAGCTTGAAGCTAAAGACCTTGAAGCTCAGCAGCTTAAGTCTTGCCCTGTGTCT
TGTTGCAAGCTCACCCGCTATTTACGCGCAAAACACTAGCGCAGCAATCATTAGCGTCAAAACGGAAACGGGTAACATTC
AGGTAAAAACCATAGCCCAAGGGTTAGAGAATGTCTGGGGTATGGCATTTTTACCCGACGGCAGCATGCTCGTGACTGAA
CGCGCCGGCAGAATGCGCATTGTCAGCGCCGCAGGTAAAGTGGGCGAACCCTTAACGGGTTTGCCACCGCTATATGCCAA
GGGCCAAGGTGGTTTACTCGATGTGGTGCTTGCGCCAGATTTTGCCAGCAGCAAAAAAATCTATTTCAGTTATTCAGAAC
CCGCAGAAGGTGATGCAAGTGAACTCAATAGCACTGCGGTGAGTTTTGCTACTCTCAATGGCAACAAGCTTGAAAATCTC
AGCCGCGTTTTTAGTCAGCAACCTAAAATCAACAGCGGCCACCATTTTGGATCTCGTTTGGTGTGGGCGCCTGACGGCAC
TTTATTTATCACACTTGGCGATCGTTACAGCAAAAAAGATAGCGCCCAAACATTAGACAATCATTTAGGCAAAGTGGTGC
GGATTAATGCCGATGGCTCAGTGCCTAAGGATAACCCCTTCATCAATACGGCGGGCGCTTTACCCGAGATCTGGTCTATT
GGTCATCGCAATATGCAAGGCGCGGCCATTAATCCCACCAGCAAAGTATTATGGACTGGCGAGCATGGACCGCAGGGCGG
CGATGAACTCAATATTGATGAGGCGGGCAAAAACTATGGCTGGCCTGTGATTACCTATGGTGAGAATTACGGTGGCGGCA
AAATAGGCGAAGGCACCCACAAAGCTGGAATGGAGCAACCCGTCTACAAGTGGGTTCCCTCAATTGCCACGGCGGGCTTT
ATGTTTTACACGGGCGATAAATTTCCGCAGTGGAAAAATAATATTTTACTCGCCAGCCTAAAGGAAAAAACGCTAGTACG
TTTAGTGCTTGATGGCGACAAGATTATTAAAGAAGAACGGCTGCTGAAAAATGAATTGGGACAAAGATTACGCTCAGTCG
TGCAAGGGCCTGATGGGTTGATTTATCTTGTGACTGATGAAGCGAAATCAAAAATTTACCAGATCTCACCGTAG

Upstream 100 bases:

>100_bases
GGTGAGTTTCGATACAAGGTCACATCGAGAAATTGCCCTTAGGTTGCTGGCTTGTTACTCTGAGCCATCATTTAGGAAAG
CACTGTGACTAAGGATAGCG

Downstream 100 bases:

>100_bases
TAATCTTAAGCACTCGCTTTAACCACAGCCTTTTAACCAGTGCAACAAGCTCAATGGTGGGAGAGGAATAAAGTTCTATA
CTGAATCGTCACATGTGCTT

Product: glucose sorbosone dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKRITFKLSSLKLKTLKLSSLSLALCLVASSPAIYAQNTSAAIISVKTETGNIQVKTIAQGLENVWGMAFLPDGSMLVTE
RAGRMRIVSAAGKVGEPLTGLPPLYAKGQGGLLDVVLAPDFASSKKIYFSYSEPAEGDASELNSTAVSFATLNGNKLENL
SRVFSQQPKINSGHHFGSRLVWAPDGTLFITLGDRYSKKDSAQTLDNHLGKVVRINADGSVPKDNPFINTAGALPEIWSI
GHRNMQGAAINPTSKVLWTGEHGPQGGDELNIDEAGKNYGWPVITYGENYGGGKIGEGTHKAGMEQPVYKWVPSIATAGF
MFYTGDKFPQWKNNILLASLKEKTLVRLVLDGDKIIKEERLLKNELGQRLRSVVQGPDGLIYLVTDEAKSKIYQISP

Sequences:

>Translated_397_residues
MKRITFKLSSLKLKTLKLSSLSLALCLVASSPAIYAQNTSAAIISVKTETGNIQVKTIAQGLENVWGMAFLPDGSMLVTE
RAGRMRIVSAAGKVGEPLTGLPPLYAKGQGGLLDVVLAPDFASSKKIYFSYSEPAEGDASELNSTAVSFATLNGNKLENL
SRVFSQQPKINSGHHFGSRLVWAPDGTLFITLGDRYSKKDSAQTLDNHLGKVVRINADGSVPKDNPFINTAGALPEIWSI
GHRNMQGAAINPTSKVLWTGEHGPQGGDELNIDEAGKNYGWPVITYGENYGGGKIGEGTHKAGMEQPVYKWVPSIATAGF
MFYTGDKFPQWKNNILLASLKEKTLVRLVLDGDKIIKEERLLKNELGQRLRSVVQGPDGLIYLVTDEAKSKIYQISP
>Mature_397_residues
MKRITFKLSSLKLKTLKLSSLSLALCLVASSPAIYAQNTSAAIISVKTETGNIQVKTIAQGLENVWGMAFLPDGSMLVTE
RAGRMRIVSAAGKVGEPLTGLPPLYAKGQGGLLDVVLAPDFASSKKIYFSYSEPAEGDASELNSTAVSFATLNGNKLENL
SRVFSQQPKINSGHHFGSRLVWAPDGTLFITLGDRYSKKDSAQTLDNHLGKVVRINADGSVPKDNPFINTAGALPEIWSI
GHRNMQGAAINPTSKVLWTGEHGPQGGDELNIDEAGKNYGWPVITYGENYGGGKIGEGTHKAGMEQPVYKWVPSIATAGF
MFYTGDKFPQWKNNILLASLKEKTLVRLVLDGDKIIKEERLLKNELGQRLRSVVQGPDGLIYLVTDEAKSKIYQISP

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=257, Percent_Identity=25.2918287937743, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI187936955, Length=258, Percent_Identity=25.1937984496124, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI124248546, Length=259, Percent_Identity=25.0965250965251, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI20143973, Length=232, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1787060, Length=350, Percent_Identity=46.5714285714286, Blast_Score=322, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 42966; Mature: 42966

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRITFKLSSLKLKTLKLSSLSLALCLVASSPAIYAQNTSAAIISVKTETGNIQVKTIAQ
CCEEEEEEEEEEEEEEEECHHEEEEEEEECCCEEEEECCCEEEEEEEECCCCEEEHHHHH
GLENVWGMAFLPDGSMLVTERAGRMRIVSAAGKVGEPLTGLPPLYAKGQGGLLDVVLAPD
HHHHHCCEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCEEEEEECCC
FASSKKIYFSYSEPAEGDASELNSTAVSFATLNGNKLENLSRVFSQQPKINSGHHFGSRL
CCCCCEEEEEECCCCCCCHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEE
VWAPDGTLFITLGDRYSKKDSAQTLDNHLGKVVRINADGSVPKDNPFINTAGALPEIWSI
EECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHC
GHRNMQGAAINPTSKVLWTGEHGPQGGDELNIDEAGKNYGWPVITYGENYGGGKIGEGTH
CCCCCCCCEECCCCEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCH
KAGMEQPVYKWVPSIATAGFMFYTGDKFPQWKNNILLASLKEKTLVRLVLDGDKIIKEER
HCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHH
LLKNELGQRLRSVVQGPDGLIYLVTDEAKSKIYQISP
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MKRITFKLSSLKLKTLKLSSLSLALCLVASSPAIYAQNTSAAIISVKTETGNIQVKTIAQ
CCEEEEEEEEEEEEEEEECHHEEEEEEEECCCEEEEECCCEEEEEEEECCCCEEEHHHHH
GLENVWGMAFLPDGSMLVTERAGRMRIVSAAGKVGEPLTGLPPLYAKGQGGLLDVVLAPD
HHHHHCCEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCEEEEEECCC
FASSKKIYFSYSEPAEGDASELNSTAVSFATLNGNKLENLSRVFSQQPKINSGHHFGSRL
CCCCCEEEEEECCCCCCCHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEE
VWAPDGTLFITLGDRYSKKDSAQTLDNHLGKVVRINADGSVPKDNPFINTAGALPEIWSI
EECCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCHHHHHC
GHRNMQGAAINPTSKVLWTGEHGPQGGDELNIDEAGKNYGWPVITYGENYGGGKIGEGTH
CCCCCCCCEECCCCEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCH
KAGMEQPVYKWVPSIATAGFMFYTGDKFPQWKNNILLASLKEKTLVRLVLDGDKIIKEER
HCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHH
LLKNELGQRLRSVVQGPDGLIYLVTDEAKSKIYQISP
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]