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The map label for this gene is ykoW [H]

Identifier: 126174964

GI number: 126174964

Start: 3237627

End: 3241886

Strand: Direct

Name: ykoW [H]

Synonym: Sbal_2757

Alternate gene names: 126174964

Gene position: 3237627-3241886 (Clockwise)

Preceding gene: 126174963

Following gene: 126174965

Centisome position: 63.14

GC content: 36.36

Gene sequence:

>4260_bases
ATGCCTAAAGCACTCTTTAAAATCGTCTTGCTCGCTTTCTTTGGCTTGCATGCATTCGAAGACGTAAACGCATCTCCCTT
TTCTGATAAATCTCCAATTATTCTCCAATCACAATCTTTTGGTGTCCCGCAAGGACTTTCCCAAAGCACAGTTACGTCTA
TAGTCCAGGACCATGATGGCTATCTATGGATTGGAACATTTAATGGACTTAATCGATTTGATGGGAAAAACTTTAAGCAT
TTTTATGCTAATGATGCCAGAACAGGCCTTCCCAGTTCTTTTATCAGAAGTTTACTCATTGATGAACAAGGCGTGTTATA
TGTTGGAACCGATAGTGGTCTAGTCGTATATGATAAACTGCAAGAATCATTTTCTCATTATGGCCTATCGGTAAATGACT
CCCCAGTCTGGAGCCTCAACTCAAGTGATAAGAGTTTAATTGTTGGAACCAACAAAGCAATTATTGATATAAGTAACAAA
GAGCAAACTTATGAACTTTCAAAGAAAGGCCTAAGTGAAATTAAAAAAACGATAAAAGTAGGCGACGATTATTATATAAG
AGACTATGCAGGTACATTATTTGAACTAAGCGGGAGTGAGTTAAAAGAGATAGCTCGAAAAACAATGGATTTCGAGCAAA
AGAATGACACGACAATGCTAATATCATTCAGTGATGGATTATATGAATACGAAGGCAATGAAATAGTAAAAGTCGATAAT
CGAGCGTTTTCATTACTTACAAAATACAAAAAAAACATATATGGCTTCACAAATGAAAATGTTGTTGATATTTCCAACAA
CACTACTATTGGACTTTTATCTCCAGATAGACCTGACAAAACATCTTCATTTTTTGCAACCGAAGATATGTTTGTATTAG
GAAGTATTGATCAAGGCATCACTATTGTAAAAAAAGTAAATAATTTAGTGCAAAAAACTAACTTAACGACAGATAGCACA
TGGCATCTTACAAAAAACACTAAAGGTTTTCTGGTTTCATCTGACTCTGAAAAAATAAAACTTTTTGATGAAAATTTGAA
CCTAATAAAAAGCTTCAACACTCATACTCAAGGATACAAATACGCAGTTCTAAGTGACGATGGGCTTTATTTTGGTACTA
ATACAGGGTTGTTTTTACAGAAAGATGATTCATCCAAGTTGATTAGCAAAAATATAATATCATCACTCTCTATTAATGAA
AATAGTTTGACAATTGCTGCTGGCACACCTGATGGTAAAGTTTTAATCATCAAAAATGGTGAAATTACTAACAGCATTGA
TACAAAAAAGAATGAGCCAATTTTTGACGTAGAGTTAAAATCTGACAACCTAATATATATAGCTGGACAAGATGGACTAA
AAAAATATGAAAATGGATTATTAGAAAACTTAAGCAATGAAATAACTTACAGCATCGAAAAAAGTGATAATGGCATTTAC
TTCGGAACATCAACATCACTGATGCTTTATAATGATACCAATAAAAAAATTTCGAGAATACTTTCTGACAATAAAGAGAT
CTACGCCATTGTAGATAATGATGGTTTTATAACAGCCTCATCACTAAGTGAAGTCATTATTTTTGAAAAAAACAGTAAAG
TATCTTATATCTTAAAAACATCAAATGGGAGTCAATATGAGTACAACGCTCCCAATGGTATCAATATAAACGGTAACACT
CTACTTGCGGGGATTAGTGGGATTAGTCTAGTATCTCCTAAAGATGTTGTAAGTTATGTAAAGAAAAGCAAGGTAAATAA
AACAGAAATATCAGATTTCTTAGTATTTAATATAGTTCAAAATCAAGAAAGTAACTATCTAGTACAATCAATCGCAGCAT
CTAATGAAATATCATTGAAATACTCTGACTATCCATTTTCGTTCAACTTTATATCTCCTATGTCAGACGACTCATCAACT
AACTACTACTATAGAATGTTCGGTCTTTCTGATATATGGATACCTGCAAATGGAACAAACTCAGCAACATATACAAACCT
ATCTCCAGGAAATTATACTTTTCAAGTTTATTCTGTTAATTCACTTTCCGGTGAAAAAGCAGCAACAAAAGAGCTTACTG
TCATTATAACACCTCCTTGGTGGTCATCATTTCAAGCAAAATCTATTTATGCTGCTATTGTATTATTTATTTCCTACCTT
GTGACAAAAACCATATTACGTCGTAGAGAAACACAAAGACAGATTGTACTCAGTGAAGAACGATTAAAACTATCATTATG
GGGAAGTGGTGATGAAATGTGGGACTGGGATATTGAAACTGGCAACATTTTCCGCTCAAATATCTGGGGAGCACTTGAAT
TCCCCCGTGATGGACACCGTTCTGGTAAATCAGATGAAGAGAGCAATATACATCCAATGGATCAAGAGCGTGTTCGAGAA
GCGCTCAATAAGCATTTTTATGGTGAAACAGATCATTTTGAAGCCGCATACCGAGTAAAAGGTAAAGACGACAATTGGGT
ATGGATCTTAGACCGCGCCAAAATTGTAGAACGTGATGAAAAAGATAATGCCCTGCGAATGACTGGAACGATTAAGAATA
TTAGTCAATTTAAACAAAAAGAAGAACAACTAAAACTCTTTGAAAAGGCTATTGAAAATATTTCGGAAGGCATGTTTATC
CTCGACAGCGAATACCGTTTTGTCGAAGTTAATGAAGCTTGCTGTAAGATTTCATTACGTAACAGAACTGATTTTATTGG
TAACTTACTCACATTTGATTTATATCCTGAAACCTTCTCCACCCAAATCAGGACCATGTTGAAACAACAAGGTCGCTGGG
CAAATGAAGTAGAAGCAGCCAGAGGAGATAAAAGTCACTTCCACATGGAGCTCACTATCGATGCTATCTATGATGAGTTA
GGCGAATTGTCACACTATGTCGGGGTTTTTTCGGATATTTCGAGACGAAAACAGCAAGAAGAAGAACTTAGAAAACTAAC
CAATAATGATCTTTTAACCGGACTACCTAATCGCTCCAACTTACAAGTGACCTTAAGTAACTTAGTGAATCGAGAAATAG
CTCATGCGCTAATGGTGCTTGACCTTGATAATTTTAAGCGTATTAATGATTCATTAGGTCACCAGATTGGAGATACATTA
TTAAAGCTCGTTGCTGCCCGCATTAAGTCCTTACTTCCTAAAAATACCAGTATTTACCGTCTAGGCGGAGATGAATTCGC
CATTGTATTAGATAAAAACTCAGATATAAGCGCCAGTGCTGCCATCGCTAACCGTATTATCGAAGGGTTAAAACCCGCTT
TTGAAGTGAGTAATGAGCAACTAGTCCTAGGATTAAGTATTGGTATAGTGCTATTCCCAGAAGATGAGCAAAGCGAGCAA
GCATTACTGAGGAAAGCAGATATTGCCATGTACCATGCTAAGTCAGCGGGAGGTAATTGCTATCAGTTTTATTCAGAGTC
ATTAAATCAGCATGCGATTAGGCAGTTAGAAATAGAGAATCTTATCCGTGAAGGCTTAAAAGATGATCTATTTGAAGTTT
ATTATCAGCCTAAGGTTGATCTTAAGCGTGGTAAAATTGCAGGCATGGAGGCTTTGGTCAGATTAAATCATCCAATACAT
GGTTTGATACCCCCAAATGATTTTATTCCACTTGCTGAGGAAAACGGCTTAATTGTTGAAATTGGTGAAATCGTCTTACG
CAAAGCCTGTTTCGCAGCGCAGAAATGGCGTGAACAAGGAATATTCAGCGGCAGAGTCGCCGTCAATTTATCGTCACGTC
AATTTGCACTCCCCGATATTCAACAGCGAATAGAGTCGATATTAAGACTCACCAAACTCCCCGCATGTCATCTTGAATTA
GAAATAACTGAAGGTACTGTCATTAAGCAGCCGGAAACGGCGATTGTTGTCATGCAGCAACTGGCGAAAATGGGCGTTAG
CTTGGCACTCGATGATTTCGGCACTGGGTACTCATCCCTTTCATACTTAAAACGTTTCCCGATTCATACTTTAAAAATTG
ATAAAGCTTTTGTTGACGATATTGATAAGTCTGATCGCGATCTCAAAATGGTCGATTCTATTATCACTATCGCCCATAAC
ATGGGGCTTTCTGTTGTGGGTGAAGGAGTAGAACAGACTGCGCAACTAAACATTTTACGAGCACTTAACTGTGAAGAGAT
CCAAGGCTATATCTTTAGTAAGGCTATAAAAGAGACCGAGTTTACCCTGCTACTCCAAGAAGACATGATAAAGCCAAACA
CCCAAAGTAACATTAATTAA

Upstream 100 bases:

>100_bases
GGATTTCTAGCCGCCTCCGCTTTGACAAAGCCCTCACTTTCTGGAAAAGTGATGTAACACAATTGTTTCATGGCATCCTC
GGATAATAAGAATAAACACT

Downstream 100 bases:

>100_bases
TCATTTAAATCTCAATTTGATTGCGGTTTACAACATTGGCACAACAAGTGCAACAACAAGTGCAACAACAAGTGCAGTAG
CACTATCAGTGTCAATAATA

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1419; Mature: 1418

Protein sequence:

>1419_residues
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKH
FYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNK
EQTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
RAFSLLTKYKKNIYGFTNENVVDISNNTTIGLLSPDRPDKTSSFFATEDMFVLGSIDQGITIVKKVNNLVQKTNLTTDST
WHLTKNTKGFLVSSDSEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINE
NSLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELKSDNLIYIAGQDGLKKYENGLLENLSNEITYSIEKSDNGIY
FGTSTSLMLYNDTNKKISRILSDNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNT
LLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLVQSIAASNEISLKYSDYPFSFNFISPMSDDSST
NYYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYSVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
VTKTILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVRE
ALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFI
LDSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTL
LKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQ
ALLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPIH
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLEL
EITEGTVIKQPETAIVVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHN
MGLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQEDMIKPNTQSNIN

Sequences:

>Translated_1419_residues
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKH
FYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNK
EQTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
RAFSLLTKYKKNIYGFTNENVVDISNNTTIGLLSPDRPDKTSSFFATEDMFVLGSIDQGITIVKKVNNLVQKTNLTTDST
WHLTKNTKGFLVSSDSEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINE
NSLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELKSDNLIYIAGQDGLKKYENGLLENLSNEITYSIEKSDNGIY
FGTSTSLMLYNDTNKKISRILSDNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNT
LLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLVQSIAASNEISLKYSDYPFSFNFISPMSDDSST
NYYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYSVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
VTKTILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVRE
ALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFI
LDSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTL
LKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQ
ALLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPIH
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLEL
EITEGTVIKQPETAIVVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHN
MGLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQEDMIKPNTQSNIN
>Mature_1418_residues
PKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDGYLWIGTFNGLNRFDGKNFKHF
YANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKLQESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKE
QTYELSKKGLSEIKKTIKVGDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDNR
AFSLLTKYKKNIYGFTNENVVDISNNTTIGLLSPDRPDKTSSFFATEDMFVLGSIDQGITIVKKVNNLVQKTNLTTDSTW
HLTKNTKGFLVSSDSEKIKLFDENLNLIKSFNTHTQGYKYAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINEN
SLTIAAGTPDGKVLIIKNGEITNSIDTKKNEPIFDVELKSDNLIYIAGQDGLKKYENGLLENLSNEITYSIEKSDNGIYF
GTSTSLMLYNDTNKKISRILSDNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKTSNGSQYEYNAPNGININGNTL
LAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQNQESNYLVQSIAASNEISLKYSDYPFSFNFISPMSDDSSTN
YYYRMFGLSDIWIPANGTNSATYTNLSPGNYTFQVYSVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYLV
TKTILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHRSGKSDEESNIHPMDQERVREA
LNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDEKDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFIL
DSEYRFVEVNEACCKISLRNRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDELG
ELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVLDLDNFKRINDSLGHQIGDTLL
KLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASAAIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQA
LLRKADIAMYHAKSAGGNCYQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPIHG
LIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDIQQRIESILRLTKLPACHLELE
ITEGTVIKQPETAIVVMQQLAKMGVSLALDDFGTGYSSLSYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNM
GLSVVGEGVEQTAQLNILRALNCEEIQGYIFSKAIKETEFTLLLQEDMIKPNTQSNIN

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=437, Percent_Identity=39.5881006864989, Blast_Score=313, Evalue=7e-86,
Organism=Escherichia coli, GI87081921, Length=449, Percent_Identity=32.293986636971, Blast_Score=248, Evalue=3e-66,
Organism=Escherichia coli, GI226510982, Length=444, Percent_Identity=28.3783783783784, Blast_Score=178, Evalue=2e-45,
Organism=Escherichia coli, GI1786507, Length=267, Percent_Identity=29.2134831460674, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1788502, Length=278, Percent_Identity=32.3741007194245, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=229, Percent_Identity=33.1877729257642, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1790496, Length=262, Percent_Identity=30.1526717557252, Blast_Score=120, Evalue=8e-28,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=30.2521008403361, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI87081980, Length=245, Percent_Identity=31.4285714285714, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1787055, Length=237, Percent_Identity=30.8016877637131, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI87082096, Length=421, Percent_Identity=26.603325415677, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1788849, Length=241, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1788381, Length=437, Percent_Identity=24.9427917620137, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI145693134, Length=185, Percent_Identity=34.5945945945946, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=35.9756097560976, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.7560975609756, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.3030303030303, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI87081881, Length=184, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787802, Length=159, Percent_Identity=31.4465408805031, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789650, Length=446, Percent_Identity=20.1793721973094, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788085, Length=187, Percent_Identity=28.3422459893048, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 159715; Mature: 159583

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDG
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCC
YLWIGTFNGLNRFDGKNFKHFYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKL
EEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
QESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKEQTYELSKKGLSEIKKTIKV
HHHHHHCCCCCCCCCEEEECCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
GDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
CCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECC
RAFSLLTKYKKNIYGFTNENVVDISNNTTIGLLSPDRPDKTSSFFATEDMFVLGSIDQGI
HHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCH
TIVKKVNNLVQKTNLTTDSTWHLTKNTKGFLVSSDSEKIKLFDENLNLIKSFNTHTQGYK
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCCHHHHHCCCCCCCEE
YAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINENSLTIAAGTPDGKVLIIKNG
EEEEECCCEEEECCCEEEEEECCCHHHHHHHHHHHCEECCCCEEEEECCCCCEEEEEECC
EITNSIDTKKNEPIFDVELKSDNLIYIAGQDGLKKYENGLLENLSNEITYSIEKSDNGIY
CCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FGTSTSLMLYNDTNKKISRILSDNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKT
EECCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEC
SNGSQYEYNAPNGININGNTLLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQ
CCCCEEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHEEEEEEEE
NQESNYLVQSIAASNEISLKYSDYPFSFNFISPMSDDSSTNYYYRMFGLSDIWIPANGTN
CCCCCHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
SATYTNLSPGNYTFQVYSVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
CCEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
VTKTILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHR
HHHHHHHHHHHHHHEEEECCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCC
SGKSDEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHCCCC
KDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFILDSEYRFVEVNEACCKISLR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEC
NRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
CCHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHH
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEHHHHHHHHHHHHEEEE
DLDNFKRINDSLGHQIGDTLLKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHH
AIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQALLRKADIAMYHAKSAGGNC
HHHHHHHHHCCHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHEEEEECCCCCCH
YQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEE
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDI
ECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
QQRIESILRLTKLPACHLELEITEGTVIKQPETAIVVMQQLAKMGVSLALDDFGTGYSSL
HHHHHHHHHHHCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEECCCCCCHHHH
SYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVVGEGVEQTAQLNILR
HHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHH
ALNCEEIQGYIFSKAIKETEFTLLLQEDMIKPNTQSNIN
HCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCC
>Mature Secondary Structure 
PKALFKIVLLAFFGLHAFEDVNASPFSDKSPIILQSQSFGVPQGLSQSTVTSIVQDHDG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCC
YLWIGTFNGLNRFDGKNFKHFYANDARTGLPSSFIRSLLIDEQGVLYVGTDSGLVVYDKL
EEEEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCEEEEHHH
QESFSHYGLSVNDSPVWSLNSSDKSLIVGTNKAIIDISNKEQTYELSKKGLSEIKKTIKV
HHHHHHCCCCCCCCCEEEECCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHC
GDDYYIRDYAGTLFELSGSELKEIARKTMDFEQKNDTTMLISFSDGLYEYEGNEIVKVDN
CCCEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCEEEEECC
RAFSLLTKYKKNIYGFTNENVVDISNNTTIGLLSPDRPDKTSSFFATEDMFVLGSIDQGI
HHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEEECCEEEEECCCCCH
TIVKKVNNLVQKTNLTTDSTWHLTKNTKGFLVSSDSEKIKLFDENLNLIKSFNTHTQGYK
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEEEEECCCHHHHHCCCCCCCEE
YAVLSDDGLYFGTNTGLFLQKDDSSKLISKNIISSLSINENSLTIAAGTPDGKVLIIKNG
EEEEECCCEEEECCCEEEEEECCCHHHHHHHHHHHCEECCCCEEEEECCCCCEEEEEECC
EITNSIDTKKNEPIFDVELKSDNLIYIAGQDGLKKYENGLLENLSNEITYSIEKSDNGIY
CCCCCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FGTSTSLMLYNDTNKKISRILSDNKEIYAIVDNDGFITASSLSEVIIFEKNSKVSYILKT
EECCCEEEEEECCCHHHHHHHCCCCEEEEEECCCCEEECCCCCEEEEEECCCCEEEEEEC
SNGSQYEYNAPNGININGNTLLAGISGISLVSPKDVVSYVKKSKVNKTEISDFLVFNIVQ
CCCCEEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHEEEEEEEE
NQESNYLVQSIAASNEISLKYSDYPFSFNFISPMSDDSSTNYYYRMFGLSDIWIPANGTN
CCCCCHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
SATYTNLSPGNYTFQVYSVNSLSGEKAATKELTVIITPPWWSSFQAKSIYAAIVLFISYL
CCEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHH
VTKTILRRRETQRQIVLSEERLKLSLWGSGDEMWDWDIETGNIFRSNIWGALEFPRDGHR
HHHHHHHHHHHHHHEEEECCEEEEEEECCCCCEEEEECCCCCEEECCCCEEEECCCCCCC
SGKSDEESNIHPMDQERVREALNKHFYGETDHFEAAYRVKGKDDNWVWILDRAKIVERDE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCHHHCCCC
KDNALRMTGTIKNISQFKQKEEQLKLFEKAIENISEGMFILDSEYRFVEVNEACCKISLR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEEC
NRTDFIGNLLTFDLYPETFSTQIRTMLKQQGRWANEVEAARGDKSHFHMELTIDAIYDEL
CCHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHH
GELSHYVGVFSDISRRKQQEEELRKLTNNDLLTGLPNRSNLQVTLSNLVNREIAHALMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEHHHHHHHHHHHHEEEE
DLDNFKRINDSLGHQIGDTLLKLVAARIKSLLPKNTSIYRLGGDEFAIVLDKNSDISASA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEEECCCCCCHHH
AIANRIIEGLKPAFEVSNEQLVLGLSIGIVLFPEDEQSEQALLRKADIAMYHAKSAGGNC
HHHHHHHHHCCHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHEEEEECCCCCCH
YQFYSESLNQHAIRQLEIENLIREGLKDDLFEVYYQPKVDLKRGKIAGMEALVRLNHPIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEE
GLIPPNDFIPLAEENGLIVEIGEIVLRKACFAAQKWREQGIFSGRVAVNLSSRQFALPDI
ECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
QQRIESILRLTKLPACHLELEITEGTVIKQPETAIVVMQQLAKMGVSLALDDFGTGYSSL
HHHHHHHHHHHCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHCCCEEEECCCCCCHHHH
SYLKRFPIHTLKIDKAFVDDIDKSDRDLKMVDSIITIAHNMGLSVVGEGVEQTAQLNILR
HHHHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHH
ALNCEEIQGYIFSKAIKETEFTLLLQEDMIKPNTQSNIN
HCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]