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The map label for this gene is mdtA [H]

Identifier: 126174734

GI number: 126174734

Start: 2945672

End: 2946736

Strand: Direct

Name: mdtA [H]

Synonym: Sbal_2521

Alternate gene names: 126174734

Gene position: 2945672-2946736 (Clockwise)

Preceding gene: 126174733

Following gene: 126174735

Centisome position: 57.45

GC content: 46.38

Gene sequence:

>1065_bases
ATGGAAAAGTCAAACATTGCTAAATTCGCCCTACCCCTGCTAATGATTTCAATGCTAGCAGCCTGTGGTAAGGAAGAAGT
GGCCAAAAAAGAAGAAAAATATGCCATTCCCGTCGAAACCACCACAGTGATGCAAGGAAACGTTTCATCTTTCTACAGCA
CAACAGCCACCTTAGAAGCACCTCAAGAAGCCAATGTCGTCAGCCGCATTTCTGGACTCATTGAATCACTTGCCGTTGAA
GAAGGTGACCGCGTACAAAAGGGCCAAGTGCTCGCCGTTATCGATGCCAAAAGACAGCAATACGATTTAGACCGCTCAGA
AGCCGAAGTTAAAATCATTGAGCAGGAATTGAATCGTCTGAAGAAAATGGGCAACAAAGAATTTATCAGCGCAGATTCGA
TGGCCAAACTTGAGTATAACTTGCAAGCCGCCATCGCCAAGAAAGATCTTGCCGAGCTACAAGTCAGAGAAAGCCGCGTA
CTATCCCCTATTAGCGGCGTCGTCGCTAAACGTTATGTGAAAGCAGGCAACATGGCGAAGGAATTTGGCGACTTGTTCTA
CATAGTCAATCAAGATGAACTCCACGGTATAGTCCATCTGCCAGAGCAACAACTTGCCAGCTTAAGACTCGGCCAAGAAG
CACAAGTGTTCAGCAATCAACAAAGTAAAAATGCTATCCATGCCAAAGTGCTGCGGATAAGCCCGATTGTTGACCCACAA
AGTGGCACGTTTAAAGTGACATTAGCCGTACCGAATCAAGAAGCGCGCCTAAAAGCAGGGATGTTTACCCGTGTAGAGCT
TAAGTATGACACCCACGAAAACGTGATTACCGTTCCCTATAGCGCCCTGATTAACCAAGATAACAGGCAAGCTTTGTATG
TTATCGATGGCACTAATGCTAACCGCCGTGAAGTCGAAATTGGCTATCGTGAAGGTGACTCTGTAGAAGTGATTGCAGGC
ATTAACCCAGGTGAACAAGTCGTGACCCGTGGCCAGCAAAACTTGAAAGACCAATCCTTAGTCGAAGTGATCACCCCACT
CGATCTTGCTTCCGCTAAGAACTGA

Upstream 100 bases:

>100_bases
CTTAAGCATAGCTTAACTATATGAAATTAAGCTATATTTAATGTTGGCACGGTTTCTGCTATCACATGGCATCACAATAA
AGACAACAGGTAACACACTT

Downstream 100 bases:

>100_bases
TAGGAGCCTTTCATGTCAATTATCAGCACTTCCGTTAAACGGCCAGTCACGGTATGGATGTTCATGCTGGCGGTAATTTT
ATTCGGTATGGTGGGATTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLRLGQEAQVFSNQQSKNAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTNANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Sequences:

>Translated_354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLRLGQEAQVFSNQQSKNAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTNANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
>Mature_354_residues
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEAPQEANVVSRISGLIESLAVE
EGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRLKKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRV
LSPISGVVAKRYVKAGNMAKEFGDLFYIVNQDELHGIVHLPEQQLASLRLGQEAQVFSNQQSKNAIHAKVLRISPIVDPQ
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTNANRREVEIGYREGDSVEVIAG
INPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=25.9036144578313, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081796, Length=330, Percent_Identity=23.6363636363636, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789929, Length=362, Percent_Identity=23.2044198895028, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39142; Mature: 39142

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRISGLIESLAVEEGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRVLSPISGVVAKRYVKAGNMAK
HHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLASLRLGQEAQVFSNQQSKNAIHAKVLRISPIVDPQ
HHCCEEEEECCCCCCCEEECCHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTNA
CCEEEEEEEECCCHHHHHCCCEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVIAGINPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MEKSNIAKFALPLLMISMLAACGKEEVAKKEEKYAIPVETTTVMQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEECCCEEEEEEECCHHHHHCCEEEECC
PQEANVVSRISGLIESLAVEEGDRVQKGQVLAVIDAKRQQYDLDRSEAEVKIIEQELNRL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHH
KKMGNKEFISADSMAKLEYNLQAAIAKKDLAELQVRESRVLSPISGVVAKRYVKAGNMAK
HHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EFGDLFYIVNQDELHGIVHLPEQQLASLRLGQEAQVFSNQQSKNAIHAKVLRISPIVDPQ
HHCCEEEEECCCCCCCEEECCHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEEEECCCCCC
SGTFKVTLAVPNQEARLKAGMFTRVELKYDTHENVITVPYSALINQDNRQALYVIDGTNA
CCEEEEEEEECCCHHHHHCCCEEEEEEEECCCCCEEEECHHHHHCCCCCEEEEEEECCCC
NRREVEIGYREGDSVEVIAGINPGEQVVTRGQQNLKDQSLVEVITPLDLASAKN
CCEEEEEEECCCCCEEEEECCCCCHHHHHCCHHCCCHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]