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The map label for this gene is gltT [H]

Identifier: 126174712

GI number: 126174712

Start: 2922399

End: 2923721

Strand: Direct

Name: gltT [H]

Synonym: Sbal_2499

Alternate gene names: 126174712

Gene position: 2922399-2923721 (Clockwise)

Preceding gene: 126174710

Following gene: 126174713

Centisome position: 57.0

GC content: 44.14

Gene sequence:

>1323_bases
ATGGCAATTTCGATAAAAAATAAACTCGGCCTTACAAGTAAAATTCTGATCGGTATGGGGACAGGCATTGCCTTAGGTCT
CCTACTCCGCAATGCCTTTCCAGAAAGCGATATCGTAAAAGACTATATTACCGAAGGTTTCTTACATGTTATCGGCACCA
TTTTCATCTCCAGCTTAAAAATGTTAGTGGTTCCTTTAGTCTTTATTTCACTAGTCTGTGGAACTTGCTCACTGAGTGAG
CCTTCAAAATTGGGCCGTTTAGGGGGCAAAACCCTCGCTTTCTATTTATTCACCACCGCTATTGCTCTCGTGGTTGCGAT
TGTCAGTGCAGTCCTTATACATCCTGGGAACGCTTCACTGGCTACAGAGAAAATGGAGTACATCGCCAAAGAAGCGCCAA
GTCTTTCAAGCGTGATTATCAATATCGTCCCCACCAATCCGATGCAAGCATTGAGTGAAGGCAATATGCTGCAAATCATT
ATTTTTGCGGTGATTTTTGGCTTTGCTATTGCCCATATTGGTGAGAGAGGTAAACGCGTTGCGGCTTTGTTTGAAGATTT
AAATGAAGTCATCATGCGCGTCGTGACACTGATCATGCAGCTTGCACCTTATGGTGTGTTTGCGCTGATGGCAAAACTTG
CATTAACGCTCGGTTTAGAAACCTTTGGTAGCGTAGTTAAATATTTCTTCGTGGTTCTCGGTGTTTTACTGGTCCATGCA
TTTATTGTTTACCCTACACTTCTAAAACTTTTCTCAGGCCTCAATCCCTTTATTTTCATTCGTAAAATGCGTGATGTGCA
GCTGTTTGCTTTTTCAACAGCAAGTTCAAATGCCACTTTACCGATTACCATAGAAGCCTCTGAGCATAGATTAGGTGTCG
ATAATAAGATTGCCGCCTTTACGCTCCCGTTAGGTGCAACCATTAACATGGATGGCACTGCAATCATGCAAGGTGTGGCC
ACAGTGTTTATCGCCCAGGTTTTTGGCATTGAACTCTCACTCACCGATTATGCCGCCGTTGTTGTGACAGCGACATTGGC
ATCAATTGGTACCGCAGGCGTTCCGGGTGTCGGACTTATCATGCTGGCCATGGTATTGAATCAAGTTGGCTTACCGGTTG
AAGGTATTGCACTGATTATCGGTGTTGATCGCCTACTCGACATGGTACGTACCGCAGTAAACGTCACCGGTGATTGTGTG
GCGACCGTGGTCATTGCGAAATCTGAAGGTGAATTTAACGAGCAAGTGTTTAACGACACTCAAGCGGGTAAGGTTGCTAG
AAATTTTGATGAGCAAGTTCATCATTCAAATAGCTCTAACTAG

Upstream 100 bases:

>100_bases
CAAATACTTTAACGCTATTTGTCATTTCATCTTCGCCGTTTTCTTGCTAGTCTTGTGAGCGCCAAAAAATAGAATGTATA
AAAAACACACAGGACTCACC

Downstream 100 bases:

>100_bases
CCTTAGTTAAATACCCATCACGCCCAGCCTCTGTGTTGGGCGTTTTTGTTTGCACTTTTTGTTTACACTTTTATCTGTAC
TTAGCCCAATTAATTTTTCT

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVIINIVPTNPMQALSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLVHA
FIVYPTLLKLFSGLNPFIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN

Sequences:

>Translated_440_residues
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSE
PSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVIINIVPTNPMQALSEGNMLQII
IFAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLVHA
FIVYPTLLKLFSGLNPFIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVA
TVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCV
ATVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN
>Mature_439_residues
AISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLKMLVVPLVFISLVCGTCSLSEP
SKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASLATEKMEYIAKEAPSLSSVIINIVPTNPMQALSEGNMLQIII
FAVIFGFAIAHIGERGKRVAALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLVHAF
IVYPTLLKLFSGLNPFIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAFTLPLGATINMDGTAIMQGVAT
VFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLIMLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVA
TVVIAKSEGEFNEQVFNDTQAGKVARNFDEQVHHSNSSN

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=411, Percent_Identity=35.5231143552311, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI40254478, Length=509, Percent_Identity=30.6483300589391, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI66773030, Length=405, Percent_Identity=34.0740740740741, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4827012, Length=285, Percent_Identity=41.0526315789474, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI21314632, Length=444, Percent_Identity=31.7567567567568, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI194239697, Length=428, Percent_Identity=32.2429906542056, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI5032093, Length=372, Percent_Identity=36.5591397849462, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI223468566, Length=253, Percent_Identity=38.7351778656126, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI223468564, Length=247, Percent_Identity=39.2712550607287, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI262359914, Length=344, Percent_Identity=33.1395348837209, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI301601644, Length=170, Percent_Identity=40.5882352941176, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790514, Length=443, Percent_Identity=34.9887133182844, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789947, Length=435, Percent_Identity=31.264367816092, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1788024, Length=417, Percent_Identity=31.89448441247, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789473, Length=379, Percent_Identity=29.023746701847, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71983106, Length=434, Percent_Identity=33.4101382488479, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71983099, Length=434, Percent_Identity=33.4101382488479, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17537407, Length=484, Percent_Identity=34.7107438016529, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI193206505, Length=395, Percent_Identity=35.9493670886076, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI71996953, Length=446, Percent_Identity=33.1838565022422, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI193206654, Length=432, Percent_Identity=32.6388888888889, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17541374, Length=392, Percent_Identity=33.1632653061224, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24583025, Length=437, Percent_Identity=32.0366132723112, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI17137668, Length=437, Percent_Identity=32.0366132723112, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24583023, Length=437, Percent_Identity=32.0366132723112, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281360481, Length=452, Percent_Identity=30.7522123893805, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281360483, Length=452, Percent_Identity=30.7522123893805, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17137666, Length=452, Percent_Identity=30.7522123893805, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 46808; Mature: 46677

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLK
CEEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATEKMEYIAKEAPSLSSVIINIVPTNPMQALSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLVHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPFIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAF
HHHHHHHHHHHCCCCHHEEHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNEQVFNDT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCC
QAGKVARNFDEQVHHSNSSN
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AISIKNKLGLTSKILIGMGTGIALGLLLRNAFPESDIVKDYITEGFLHVIGTIFISSLK
EEEECCCCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVPLVFISLVCGTCSLSEPSKLGRLGGKTLAFYLFTTAIALVVAIVSAVLIHPGNASL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATEKMEYIAKEAPSLSSVIINIVPTNPMQALSEGNMLQIIIFAVIFGFAIAHIGERGKRV
HHHHHHHHHHCCCCHHHEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AALFEDLNEVIMRVVTLIMQLAPYGVFALMAKLALTLGLETFGSVVKYFFVVLGVLLVHA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVYPTLLKLFSGLNPFIFIRKMRDVQLFAFSTASSNATLPITIEASEHRLGVDNKIAAF
HHHHHHHHHHHCCCCHHEEHHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEEE
TLPLGATINMDGTAIMQGVATVFIAQVFGIELSLTDYAAVVVTATLASIGTAGVPGVGLI
EECCCCEECCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHH
MLAMVLNQVGLPVEGIALIIGVDRLLDMVRTAVNVTGDCVATVVIAKSEGEFNEQVFNDT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHCCC
QAGKVARNFDEQVHHSNSSN
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]