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The map label for this gene is hscB [H]

Identifier: 126174607

GI number: 126174607

Start: 2785152

End: 2785676

Strand: Reverse

Name: hscB [H]

Synonym: Sbal_2394

Alternate gene names: 126174607

Gene position: 2785676-2785152 (Counterclockwise)

Preceding gene: 126174608

Following gene: 126174606

Centisome position: 54.33

GC content: 46.67

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAAATTTTCCCCTGCCTTCGATATTGATACCGCCTTACTTGCAGAACGCTATCGCGAACT
GCAACGGGCGGTTCATCCCGATAAATTTGCCAATGATACTGAGCAGCAAAAATTGCTGTCGGTGCAGCGCACGGCGCAAG
TCAATGATGGTTTTCAAACCTTAAAAGATCCCATTCGCCGTGCCGAGCATATGTTGTCGCTGCGTGGCATTGAATTAAGC
CATGAAACCACGACAGTGAAAGATACTGGCTTCTTGATGCAGCAAATGGAATGGCGTGAAGCGTTGGAAGACATACGCGA
TAGTGCCGATCCTCAAGCGAGTATTGACGCGTTATATCAATCGTTTGCAGAGTACCGCGCGCAACTCACTCAGCAATTGA
CTCAACTGTTAACCAGTGAGCAGGCTGAAGATGCATTGTTAGCGGCGGATCAAGTTCGCAAACTCAAATTTATGGCAAAA
TTACACGACGAGTTGACCAGAGTCGAAGACGCTCTGTTAGATTGA

Upstream 100 bases:

>100_bases
AAAGAAGGGCTGAATGAAGGCTTCCAATTTAACAATCCTAACGCAAAAGGTGAGTGTGGTTGCGGTGAGAGTTTCACTGT
TTAACCGCTAAAGTTGACGC

Downstream 100 bases:

>100_bases
TTTTCCGTGTTTATGTTACTTTGCTGACTCAAGCACGCTTGAGTTGGCATTACTAAGTTGGATATATATGGCCCTTTTGC
AGATAGCTGAGCCCGGTCAA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQSFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD

Sequences:

>Translated_174_residues
MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQSFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD
>Mature_174_residues
MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELS
HETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQSFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAK
LHDELTRVEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=108, Percent_Identity=37.962962962963, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788876, Length=177, Percent_Identity=40.6779661016949, Blast_Score=123, Evalue=8e-30,
Organism=Drosophila melanogaster, GI161084223, Length=108, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20153; Mature: 20153

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQT
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQ
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQT
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQ
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA