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The map label for this gene is dinG [H]

Identifier: 126174568

GI number: 126174568

Start: 2741969

End: 2742595

Strand: Direct

Name: dinG [H]

Synonym: Sbal_2355

Alternate gene names: 126174568

Gene position: 2741969-2742595 (Clockwise)

Preceding gene: 126174566

Following gene: 126174571

Centisome position: 53.48

GC content: 49.44

Gene sequence:

>627_bases
ATGCCTACATCAGCTGCTAACACTTTGGTCGTGCTCGACTTTGAAACCACGGGGCTGTCGCCCAATCAAGGGGATCGCGC
GATTGAAATCGGGGCTGTGCTGATTGAAGACGGTGTGATCACTCAAAGATTTTCTGAGTTAATGAACCCAGGATTTAGAA
TAAGTCGCTTTATTGAAGACTACACTGGGATCAGCAATCAAATGCTCAGGGACGCGGCGCCCTGCAATGAAGTGATGGCG
CGTTTTGCGGACTTTATCGCCGATCACAATTTAGTTGCCCACAATGCGGCGTTCGATCAGCGCTTTTTAGATGCGGAGTT
TGCCCAAATTCGCCATCGTTATCTTGGGCAATTTGGCTGTTCCTTGCTGGTGGCGAGACGTTTGTATCAAGCGGCACCCA
ATCATCAGTTAGGTACTTTAGTGCGCTATAAACAGTTACCAACCGATGGCACTTTTCACCGCGCCTTAGCCGATGCCGAA
ATGACCGGCCATTTGTGGCTGGCTATGCTGGCAGACCTTCAGCAAGAGTTTGGACTCTGCTCACCGACCTTTGAGTTACT
GCAAAAATTAGCGAAGAAAACCAAAGCAGAGGTGCCGAAGTTTTTACGCCAATACGCCGTCAAGTGA

Upstream 100 bases:

>100_bases
AATTTACTAACGTATTGAATTACAATCGGCTTATCTAGAAGCATTTCGCCACAAACGACGCTAATGCTGACACATCATTA
ATTGAGTCCATGTAAGATCT

Downstream 100 bases:

>100_bases
TCCAAAAAGCAACGCAGCTAAGAGGTATCAAAAAGCAAAAAACCGATAAATCCAAGGATTATCGGCGTTGTTTCAATCGG
TAAATTAAGTGACCAACGAG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPTSAANTLVVLDFETTGLSPNQGDRAIEIGAVLIEDGVITQRFSELMNPGFRISRFIEDYTGISNQMLRDAAPCNEVMA
RFADFIADHNLVAHNAAFDQRFLDAEFAQIRHRYLGQFGCSLLVARRLYQAAPNHQLGTLVRYKQLPTDGTFHRALADAE
MTGHLWLAMLADLQQEFGLCSPTFELLQKLAKKTKAEVPKFLRQYAVK

Sequences:

>Translated_208_residues
MPTSAANTLVVLDFETTGLSPNQGDRAIEIGAVLIEDGVITQRFSELMNPGFRISRFIEDYTGISNQMLRDAAPCNEVMA
RFADFIADHNLVAHNAAFDQRFLDAEFAQIRHRYLGQFGCSLLVARRLYQAAPNHQLGTLVRYKQLPTDGTFHRALADAE
MTGHLWLAMLADLQQEFGLCSPTFELLQKLAKKTKAEVPKFLRQYAVK
>Mature_207_residues
PTSAANTLVVLDFETTGLSPNQGDRAIEIGAVLIEDGVITQRFSELMNPGFRISRFIEDYTGISNQMLRDAAPCNEVMAR
FADFIADHNLVAHNAAFDQRFLDAEFAQIRHRYLGQFGCSLLVARRLYQAAPNHQLGTLVRYKQLPTDGTFHRALADAEM
TGHLWLAMLADLQQEFGLCSPTFELLQKLAKKTKAEVPKFLRQYAVK

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=177, Percent_Identity=31.638418079096, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 23364; Mature: 23233

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSAANTLVVLDFETTGLSPNQGDRAIEIGAVLIEDGVITQRFSELMNPGFRISRFIED
CCCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
YTGISNQMLRDAAPCNEVMARFADFIADHNLVAHNAAFDQRFLDAEFAQIRHRYLGQFGC
HHCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLVARRLYQAAPNHQLGTLVRYKQLPTDGTFHRALADAEMTGHLWLAMLADLQQEFGLC
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPTFELLQKLAKKTKAEVPKFLRQYAVK
CHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTSAANTLVVLDFETTGLSPNQGDRAIEIGAVLIEDGVITQRFSELMNPGFRISRFIED
CCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
YTGISNQMLRDAAPCNEVMARFADFIADHNLVAHNAAFDQRFLDAEFAQIRHRYLGQFGC
HHCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLVARRLYQAAPNHQLGTLVRYKQLPTDGTFHRALADAEMTGHLWLAMLADLQQEFGLC
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPTFELLQKLAKKTKAEVPKFLRQYAVK
CHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]