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The map label for this gene is umuD [H]

Identifier: 126174565

GI number: 126174565

Start: 2738719

End: 2739138

Strand: Direct

Name: umuD [H]

Synonym: Sbal_2352

Alternate gene names: 126174565

Gene position: 2738719-2739138 (Clockwise)

Preceding gene: 126174564

Following gene: 126174566

Centisome position: 53.41

GC content: 49.05

Gene sequence:

>420_bases
ATGATGATCCTAGGCCGCTTCGCCAAACATACCCAATATCGGCTCTCGCTATTTAGCTCCTTGATTGCCGCAGGATTTCC
GTCACCAGCCCAAGACTATGTAGAACAAACATTAGATCTCAATGAGTTATGCATCAAGCATCCCGCCGCCACGTTTTTTG
TCAAAGTCCAAGGGGATTCGATGATCGAAGCGGGGATTTTCTCCGGTGATATTTTGGTGGTGGATCGCTCATTACAGCCG
GCCCACGGGGATACCGTTGTCGCAGCGGTGAACGGCGAGTTTACTGTAAAGCAATTACAGCTGCGCCCTGTGGTGCAATT
ACTGCCACGTAATGCCTTATTCTCCCCGATTGCCATCAATGATGAGTCTGAGTTAAACATCTTTGGGGTGGTGACCAACG
TGGTGAAAAAGCTCAAATGA

Upstream 100 bases:

>100_bases
TGCGCCAGGGTCGATAACACAACTGTCTCCACATAAATTCTTTCGATAAGTTTCATTGTTAGACTATACTGTTCATACGT
ACAGTATATTGTGATTTATT

Downstream 100 bases:

>100_bases
CGCCCTCACTATTCGCACTCGTCGATTGCAATAATTTTTATGCCTCCTGTGAGCGGATGTTTAGGCCAGATTTAGCTGGC
AGGCCGATTGTAGTGTTATC

Product: putative prophage repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MMILGRFAKHTQYRLSLFSSLIAAGFPSPAQDYVEQTLDLNELCIKHPAATFFVKVQGDSMIEAGIFSGDILVVDRSLQP
AHGDTVVAAVNGEFTVKQLQLRPVVQLLPRNALFSPIAINDESELNIFGVVTNVVKKLK

Sequences:

>Translated_139_residues
MMILGRFAKHTQYRLSLFSSLIAAGFPSPAQDYVEQTLDLNELCIKHPAATFFVKVQGDSMIEAGIFSGDILVVDRSLQP
AHGDTVVAAVNGEFTVKQLQLRPVVQLLPRNALFSPIAINDESELNIFGVVTNVVKKLK
>Mature_139_residues
MMILGRFAKHTQYRLSLFSSLIAAGFPSPAQDYVEQTLDLNELCIKHPAATFFVKVQGDSMIEAGIFSGDILVVDRSLQP
AHGDTVVAAVNGEFTVKQLQLRPVVQLLPRNALFSPIAINDESELNIFGVVTNVVKKLK

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=123, Percent_Identity=60.9756097560976, Blast_Score=167, Evalue=2e-43,
Organism=Escherichia coli, GI1790476, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15241; Mature: 15241

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILGRFAKHTQYRLSLFSSLIAAGFPSPAQDYVEQTLDLNELCIKHPAATFFVKVQGDS
CEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECCCC
MIEAGIFSGDILVVDRSLQPAHGDTVVAAVNGEFTVKQLQLRPVVQLLPRNALFSPIAIN
EEECCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCEEEC
DESELNIFGVVTNVVKKLK
CCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MMILGRFAKHTQYRLSLFSSLIAAGFPSPAQDYVEQTLDLNELCIKHPAATFFVKVQGDS
CEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCEEEEEEECCCC
MIEAGIFSGDILVVDRSLQPAHGDTVVAAVNGEFTVKQLQLRPVVQLLPRNALFSPIAIN
EEECCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCEEEC
DESELNIFGVVTNVVKKLK
CCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]