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The map label for this gene is proX [H]

Identifier: 126174514

GI number: 126174514

Start: 2676650

End: 2677684

Strand: Direct

Name: proX [H]

Synonym: Sbal_2299

Alternate gene names: 126174514

Gene position: 2676650-2677684 (Clockwise)

Preceding gene: 126174513

Following gene: 126174518

Centisome position: 52.2

GC content: 45.89

Gene sequence:

>1035_bases
ATGAGACTTAAAAAAGTAATACTGGGTGCAGCGTTAGCTGCAATGACAGTGACGGGATCCGCAGCGCTTGCAGATACTCT
CAAGCCAGGAGAAGGCATAACCGTTAAACCCGCTCGGGCGACATGGGACACAGGTTTTTTTCAGGAAGCACTTGTTCGAC
GCGGTCTTGAAACGCTTGGGTATGATGTCGAAAAGCCTAAGACACTGGTCAATCCCATCTTTTATAAAACCGTCACACTC
GGTGACATTGATTATTGGGCCAATGGTTGGTTTCCAATGCATAACGATCAGCTACCGAGCAATTTCGACGAAAAAGCCGA
AAAAATTGGTTATGTTATTAAAGCCGGTGGATTAGGCGGATATTTAATCTCTAAAAAAGAAGCCGATAAATACAATATTA
CCTCTCTTGCAGATTTTAAACGCCCTGAAGTCAAGCAAGCATTTGATACTAATGGAGATGGTAAAGCGGATTTGACTGCA
TGTCCTCCTGGTTGGGGATGCGAAAAAATCATCACTCACCATATGGATGTTTACGGTCTGAAAGATTCGATTAATCCAGT
GAAAGCGGCCTATGCTGCCGGGATGGCATCCGCTATGGCGGGTTATAAAAATGGTGGCCCGATATTTTTCTATACTTGGG
CGCCCAACTGGACCATTTTTAAAATGAAGCCAGGCAAGGACGTGGTATGGATAAACGTGCCTGAAATCAAGCCAACAAAA
GCCCAGAGTGCTGCCGTTGATCGGATGACGGTAAAGGGACTCGAAGGCGCGGTTTCCGATCCGATAAAACTGGGGTTTGT
CGCTTCTGACATCCAGATCGTTGCCAACAAAAAATTCGCTAAACAAAATCCCGCCGCGAGAAAGTTTTTTGAGGTATTCA
CACTACCGCTCGCCGATATCAACGAGCAGAACACGCGTATGAACGACGGTGAAAAGAGCAAGCAAGATATTCAACACCAC
GTTGATGGGTGGATTGCCAAGAACCAAGATAAATGGAACGGTTGGCTTACTGAAGCACGAAACGCGGCTCAATAG

Upstream 100 bases:

>100_bases
TTGGTTTAGCCACGGTGGGCGGTCTAGCGATTGTTTTATTAGCCATCATTCTCGATAGGATCACCCAATCAATGGCGACC
AAAAAAAATAAGGACGTAAA

Downstream 100 bases:

>100_bases
TCTCAAGCTGTAACCCTAAATCTGGCCAGTGATGATAAAACGCAAACAACATCCACTTTCGGTTTGCGTTCTATCATCAC
TGGAACTTGCTTTCGGGGTC

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRLKKVILGAALAAMTVTGSAALADTLKPGEGITVKPARATWDTGFFQEALVRRGLETLGYDVEKPKTLVNPIFYKTVTL
GDIDYWANGWFPMHNDQLPSNFDEKAEKIGYVIKAGGLGGYLISKKEADKYNITSLADFKRPEVKQAFDTNGDGKADLTA
CPPGWGCEKIITHHMDVYGLKDSINPVKAAYAAGMASAMAGYKNGGPIFFYTWAPNWTIFKMKPGKDVVWINVPEIKPTK
AQSAAVDRMTVKGLEGAVSDPIKLGFVASDIQIVANKKFAKQNPAARKFFEVFTLPLADINEQNTRMNDGEKSKQDIQHH
VDGWIAKNQDKWNGWLTEARNAAQ

Sequences:

>Translated_344_residues
MRLKKVILGAALAAMTVTGSAALADTLKPGEGITVKPARATWDTGFFQEALVRRGLETLGYDVEKPKTLVNPIFYKTVTL
GDIDYWANGWFPMHNDQLPSNFDEKAEKIGYVIKAGGLGGYLISKKEADKYNITSLADFKRPEVKQAFDTNGDGKADLTA
CPPGWGCEKIITHHMDVYGLKDSINPVKAAYAAGMASAMAGYKNGGPIFFYTWAPNWTIFKMKPGKDVVWINVPEIKPTK
AQSAAVDRMTVKGLEGAVSDPIKLGFVASDIQIVANKKFAKQNPAARKFFEVFTLPLADINEQNTRMNDGEKSKQDIQHH
VDGWIAKNQDKWNGWLTEARNAAQ
>Mature_344_residues
MRLKKVILGAALAAMTVTGSAALADTLKPGEGITVKPARATWDTGFFQEALVRRGLETLGYDVEKPKTLVNPIFYKTVTL
GDIDYWANGWFPMHNDQLPSNFDEKAEKIGYVIKAGGLGGYLISKKEADKYNITSLADFKRPEVKQAFDTNGDGKADLTA
CPPGWGCEKIITHHMDVYGLKDSINPVKAAYAAGMASAMAGYKNGGPIFFYTWAPNWTIFKMKPGKDVVWINVPEIKPTK
AQSAAVDRMTVKGLEGAVSDPIKLGFVASDIQIVANKKFAKQNPAARKFFEVFTLPLADINEQNTRMNDGEKSKQDIQHH
VDGWIAKNQDKWNGWLTEARNAAQ

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=342, Percent_Identity=42.3976608187134, Blast_Score=264, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 37863; Mature: 37863

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKKVILGAALAAMTVTGSAALADTLKPGEGITVKPARATWDTGFFQEALVRRGLETLG
CCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHC
YDVEKPKTLVNPIFYKTVTLGDIDYWANGWFPMHNDQLPSNFDEKAEKIGYVIKAGGLGG
CCCCCCHHHHCHHHEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCC
YLISKKEADKYNITSLADFKRPEVKQAFDTNGDGKADLTACPPGWGCEKIITHHMDVYGL
EEEECCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHEEEC
KDSINPVKAAYAAGMASAMAGYKNGGPIFFYTWAPNWTIFKMKPGKDVVWINVPEIKPTK
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCCC
AQSAAVDRMTVKGLEGAVSDPIKLGFVASDIQIVANKKFAKQNPAARKFFEVFTLPLADI
CHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCHHHCCHHHHHHHHHHHCCHHCC
NEQNTRMNDGEKSKQDIQHHVDGWIAKNQDKWNGWLTEARNAAQ
CCCCCCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLKKVILGAALAAMTVTGSAALADTLKPGEGITVKPARATWDTGFFQEALVRRGLETLG
CCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHC
YDVEKPKTLVNPIFYKTVTLGDIDYWANGWFPMHNDQLPSNFDEKAEKIGYVIKAGGLGG
CCCCCCHHHHCHHHEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCC
YLISKKEADKYNITSLADFKRPEVKQAFDTNGDGKADLTACPPGWGCEKIITHHMDVYGL
EEEECCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHEEEC
KDSINPVKAAYAAGMASAMAGYKNGGPIFFYTWAPNWTIFKMKPGKDVVWINVPEIKPTK
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCCC
AQSAAVDRMTVKGLEGAVSDPIKLGFVASDIQIVANKKFAKQNPAARKFFEVFTLPLADI
CHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCHHHCCHHHHHHHHHHHCCHHCC
NEQNTRMNDGEKSKQDIQHHVDGWIAKNQDKWNGWLTEARNAAQ
CCCCCCCCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]