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The map label for this gene is malZ [C]

Identifier: 126174505

GI number: 126174505

Start: 2661442

End: 2663739

Strand: Direct

Name: malZ [C]

Synonym: Sbal_2289

Alternate gene names: 126174505

Gene position: 2661442-2663739 (Clockwise)

Preceding gene: 126174504

Following gene: 126174506

Centisome position: 51.91

GC content: 46.82

Gene sequence:

>2298_bases
ATGATCCGTCAAATCTGGCTAATAGTGCTTTATTTATCCGTAGTTTACTGTTCATTTAATCCTGTCCATGCGAACACTCT
AGAGCCGAAGATATCGACGGACGTTAAACTTGAACCCGCTTTTTGGTGGGCGGGGATGCACAATCCTGAGTTACAGTTAA
TGCTGTATAGCCGCGAGCTGCCTAGCTTACCGCAGCAGCTTAAGGTTGATATCCAAGGGCAAGGCATCACGCTAAAAAGC
CTTGAACACACTGATAACCCGCATTATCTGTTTATCAATTTAGATCTTAGCCAAGCTGCGCCGCAAACCTTTGAGCTGGT
GATTTCAAGCACTGACTCGGCGTCAAAAACCAACACGCCTCTTTATCGCCTGCCCTATACGTTGCAAGGGCGCGCTAAAG
GTAGCCGTGAGCGCCAAGGGTTTAGCAATAAGGATGTGATTTACCTTATCACGCCAGACAGATTCGCCAATGGCGACACG
AGTAATGACAATCAGGCCGATATGCTAGAGCAAGTCGCAACTAACTCTCCTAGCAATTCCAACAATCCCTATTATCCCGA
TGCTCGCCATGGCGGCGATATCGCAGGGATCAGCCAGCACTTAGCGTATCTGGCAAAGCTCGGGGTGACTCAGTTATGGA
TCAATCCACTGCTTGAGAATAATCAAGCCCAATATTCATACCACGGATACTCAATTACCAATTTGTACCGCGTCGATCCC
CGCTTTGGCAGCAATGAGGATTATAAAGCCTTAGTCGCTAAGGCTAACAAGCTTGGCCTTGGGGTAATTAAAGATGTTGT
CGTGAATCATATCGGCTCTAATCATTGGTGGCTCAACGATTTACCTAGCCAAGACTGGCTCAATGACGCCACAAAAACGC
AGCTACATAATCGCGAATCTAAGCCTGACTTGATTCAGTCTGCCGATACTAAATCCAGCACTATTAAATCCAGCGTTACC
AGCCCCCGTTTTACCAATCATAGGCGCACTACAGTGCAAGATCCCTACGCGGCAGCGCAAGATCATATTGATTTTGTCGA
CGGCTGGTTTACCGACACTATGCCGGATCTGAATCAAAGCAATCCCAAACTGGCAACCTATCTTATCCAAAACAGTATTT
GGTGGGTCGAGTACGCAGGACTTTCAGGGATCCGCGAAGACACTTATTCCTACGCCGACAAAGGGTTTCTCGCTAAATGG
TCTAAGGCCGTAATGACTGAGTACCCGAATTTTAATATTGTGGGCGAAGAATGGACCGCAAACCCCATCACAGTTGCCTA
TTGGCAAAAGGGCAAAATCAATGCCGATGGCTATACCTCAGATCTACCCAGTTTAATGGACTTCCCGCTATATGAAAAAT
TAATTGCCAGCCTCAATGAGCCAGAAAGCTGGGACACAGGTTTTATCAAGCTTTACGAGATGTTAGCCAACGATCTTGTG
TATGCCGATCCCAGTAAACTAGTGCTATTTGAAGGCAATCACGACACCAATCGTATCTTCAGTTTAGTGAAAGAAAATAT
AGACTTATATAAGATGGCACTCACCTATGTGCTGACCGCCAAACGCATTCCGCAGCTGTTTTACGGTACAGAAGTGTTAA
TGACCAGCCCGACCGAAGGCCGTCACGATGGTGTTGTGCGCAGTGATTTCCCCGGTGGGTTTGCCAACAGTGCCACTAAC
GCCTTTACCGGCCAAGGGCTGAGTGAACCCCAGCGACAAGCACAGCAATTTGTCAGAACCCTACTGAATTACCGTAAACA
ATCCCCTGCGCTACAATCGGGCGATTTACTGCACTTTGTACCGCAAGATGGTGTCTATGTGCAATTTCGTTGCGTATTAA
ATGCGCCATTATCAGCTGAACAAAAAGCCGAAGCGCTCAAATCACTAATACAAAACAATTCTCTAACTCAACACAATGCC
TGCACTCAGCCCTCGGCCGACAAAGTCATGGTGATTTACAATAAAAATGACAAGGCAGTCACGCTAGATATAAACCGCTT
TGCCAGTGTACTTGGCGATAGCGGCGCCGCTACAGATATCATCAGTGGCAAAACCGTTTCACTCAATCAAGCGATAACCT
TGCCCCACGCAGGTGTCACTATTCTCGAGCTTAAGCTTAAGCCTAATTCTAAGTCTAAGACTAAGTCGCCGCAGAATGCT
GGCTTGCCGAGCCGCCAAGATTCAATGCTCTCTAGGAATCAAGCTAACGCTTTAACGCGCGCTCATACTAACAACAGTAC
AAACAACAGCGCTAATAACCTAGCGAAAAACTCAACTCAAAAAGGAACTCAGCCTTGA

Upstream 100 bases:

>100_bases
CTTCAATTAAGAAGCAGGCTTTTGCTTATGTAGATTTCAGCGATGTTAAACTTCATCATGCCAGCGCATTTTACTTCTCT
ATCTTTAAAAGGCTTACATT

Downstream 100 bases:

>100_bases
GCTTTTTATCGCCTATCGATTCCAGAGTGACTCAGAGCCAACAAGCGGCTAAATTTCCCATCGTAGCTTTACTGACCAAA
GCCCCGCAGCGCCGACAGTC

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Beta-amylase; Alpha-amylase [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MIRQIWLIVLYLSVVYCSFNPVHANTLEPKISTDVKLEPAFWWAGMHNPELQLMLYSRELPSLPQQLKVDIQGQGITLKS
LEHTDNPHYLFINLDLSQAAPQTFELVISSTDSASKTNTPLYRLPYTLQGRAKGSRERQGFSNKDVIYLITPDRFANGDT
SNDNQADMLEQVATNSPSNSNNPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENNQAQYSYHGYSITNLYRVDP
RFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNDATKTQLHNRESKPDLIQSADTKSSTIKSSVT
SPRFTNHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKW
SKAVMTEYPNFNIVGEEWTANPITVAYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEPESWDTGFIKLYEMLANDLV
YADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGRHDGVVRSDFPGGFANSATN
AFTGQGLSEPQRQAQQFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCVLNAPLSAEQKAEALKSLIQNNSLTQHNA
CTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTILELKLKPNSKSKTKSPQNA
GLPSRQDSMLSRNQANALTRAHTNNSTNNSANNLAKNSTQKGTQP

Sequences:

>Translated_765_residues
MIRQIWLIVLYLSVVYCSFNPVHANTLEPKISTDVKLEPAFWWAGMHNPELQLMLYSRELPSLPQQLKVDIQGQGITLKS
LEHTDNPHYLFINLDLSQAAPQTFELVISSTDSASKTNTPLYRLPYTLQGRAKGSRERQGFSNKDVIYLITPDRFANGDT
SNDNQADMLEQVATNSPSNSNNPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENNQAQYSYHGYSITNLYRVDP
RFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNDATKTQLHNRESKPDLIQSADTKSSTIKSSVT
SPRFTNHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKW
SKAVMTEYPNFNIVGEEWTANPITVAYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEPESWDTGFIKLYEMLANDLV
YADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGRHDGVVRSDFPGGFANSATN
AFTGQGLSEPQRQAQQFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCVLNAPLSAEQKAEALKSLIQNNSLTQHNA
CTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTILELKLKPNSKSKTKSPQNA
GLPSRQDSMLSRNQANALTRAHTNNSTNNSANNLAKNSTQKGTQP
>Mature_765_residues
MIRQIWLIVLYLSVVYCSFNPVHANTLEPKISTDVKLEPAFWWAGMHNPELQLMLYSRELPSLPQQLKVDIQGQGITLKS
LEHTDNPHYLFINLDLSQAAPQTFELVISSTDSASKTNTPLYRLPYTLQGRAKGSRERQGFSNKDVIYLITPDRFANGDT
SNDNQADMLEQVATNSPSNSNNPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENNQAQYSYHGYSITNLYRVDP
RFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNDATKTQLHNRESKPDLIQSADTKSSTIKSSVT
SPRFTNHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQSNPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKW
SKAVMTEYPNFNIVGEEWTANPITVAYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEPESWDTGFIKLYEMLANDLV
YADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEGRHDGVVRSDFPGGFANSATN
AFTGQGLSEPQRQAQQFVRTLLNYRKQSPALQSGDLLHFVPQDGVYVQFRCVLNAPLSAEQKAEALKSLIQNNSLTQHNA
CTQPSADKVMVIYNKNDKAVTLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTILELKLKPNSKSKTKSPQNA
GLPSRQDSMLSRNQANALTRAHTNNSTNNSANNLAKNSTQKGTQP

Specific function: The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=515, Percent_Identity=24.6601941747573, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1789995, Length=142, Percent_Identity=31.6901408450704, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790687, Length=89, Percent_Identity=37.0786516853933, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321726, Length=210, Percent_Identity=29.0476190476191, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324416, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322241, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322245, Length=102, Percent_Identity=37.2549019607843, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319776, Length=225, Percent_Identity=28.4444444444444, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=225, Percent_Identity=28.4444444444444, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586587, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583745, Length=87, Percent_Identity=40.2298850574713, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24586589, Length=92, Percent_Identity=36.9565217391304, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586591, Length=84, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45549022, Length=87, Percent_Identity=32.183908045977, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24586597, Length=87, Percent_Identity=35.632183908046, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24586599, Length=204, Percent_Identity=25, Blast_Score=70, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24583749, Length=196, Percent_Identity=23.469387755102, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583747, Length=196, Percent_Identity=23.469387755102, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR005085
- InterPro:   IPR008985
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR001554
- InterPro:   IPR018238
- InterPro:   IPR000125
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF03423 CBM_25; PF01373 Glyco_hydro_14 [H]

EC number: =3.2.1.2; =3.2.1.1 [H]

Molecular weight: Translated: 85419; Mature: 85419

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRQIWLIVLYLSVVYCSFNPVHANTLEPKISTDVKLEPAFWWAGMHNPELQLMLYSREL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCEEEEEECCCC
PSLPQQLKVDIQGQGITLKSLEHTDNPHYLFINLDLSQAAPQTFELVISSTDSASKTNTP
CCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEEEHHHCCCCEEEEEEECCCCCCCCCCC
LYRLPYTLQGRAKGSRERQGFSNKDVIYLITPDRFANGDTSNDNQADMLEQVATNSPSNS
EEECCEEEECCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
NNPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENNQAQYSYHGYSITNLYRVDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEECCEEEEEEEEECC
RFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNDATKTQLHNRES
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHCCCC
KPDLIQSADTKSSTIKSSVTSPRFTNHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQS
CCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCC
NPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKWSKAVMTEYPNFNIVGEEWTA
CCCEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCC
NPITVAYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEPESWDTGFIKLYEMLANDLV
CCEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEE
YADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEG
EECCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RHDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQQFVRTLLNYRKQSPALQSGDLLHFV
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PQDGVYVQFRCVLNAPLSAEQKAEALKSLIQNNSLTQHNACTQPSADKVMVIYNKNDKAV
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEE
TLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTILELKLKPNSKSKTKSPQNA
EEEHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCEEEEEEEECCCCCCCCCCCCCC
GLPSRQDSMLSRNQANALTRAHTNNSTNNSANNLAKNSTQKGTQP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIRQIWLIVLYLSVVYCSFNPVHANTLEPKISTDVKLEPAFWWAGMHNPELQLMLYSREL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCEEEEEECCCC
PSLPQQLKVDIQGQGITLKSLEHTDNPHYLFINLDLSQAAPQTFELVISSTDSASKTNTP
CCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEEEHHHCCCCEEEEEEECCCCCCCCCCC
LYRLPYTLQGRAKGSRERQGFSNKDVIYLITPDRFANGDTSNDNQADMLEQVATNSPSNS
EEECCEEEECCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
NNPYYPDARHGGDIAGISQHLAYLAKLGVTQLWINPLLENNQAQYSYHGYSITNLYRVDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEEECCEEEEEEEEECC
RFGSNEDYKALVAKANKLGLGVIKDVVVNHIGSNHWWLNDLPSQDWLNDATKTQLHNRES
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHCCCC
KPDLIQSADTKSSTIKSSVTSPRFTNHRRTTVQDPYAAAQDHIDFVDGWFTDTMPDLNQS
CCHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCC
NPKLATYLIQNSIWWVEYAGLSGIREDTYSYADKGFLAKWSKAVMTEYPNFNIVGEEWTA
CCCEEEEEECCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCC
NPITVAYWQKGKINADGYTSDLPSLMDFPLYEKLIASLNEPESWDTGFIKLYEMLANDLV
CCEEEEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEE
YADPSKLVLFEGNHDTNRIFSLVKENIDLYKMALTYVLTAKRIPQLFYGTEVLMTSPTEG
EECCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RHDGVVRSDFPGGFANSATNAFTGQGLSEPQRQAQQFVRTLLNYRKQSPALQSGDLLHFV
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PQDGVYVQFRCVLNAPLSAEQKAEALKSLIQNNSLTQHNACTQPSADKVMVIYNKNDKAV
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEE
TLDINRFASVLGDSGAATDIISGKTVSLNQAITLPHAGVTILELKLKPNSKSKTKSPQNA
EEEHHHHHHHHCCCCCCCCCCCCCEEECCCEEECCCCCEEEEEEEECCCCCCCCCCCCCC
GLPSRQDSMLSRNQANALTRAHTNNSTNNSANNLAKNSTQKGTQP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2435707; 2464578; 2438660; 1827035 [H]