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The map label for this gene is pgm [H]

Identifier: 126174441

GI number: 126174441

Start: 2573939

End: 2575591

Strand: Reverse

Name: pgm [H]

Synonym: Sbal_2225

Alternate gene names: 126174441

Gene position: 2575591-2573939 (Counterclockwise)

Preceding gene: 126174442

Following gene: 126174439

Centisome position: 50.23

GC content: 48.46

Gene sequence:

>1653_bases
GTGGCAATACATCAAAGGGCAGGACAAATCGCTAATCAGACGGATCTGGTCAATATTCCAAAACTGATGAGCCATTATTA
CAGCATCACGCCAAATATGGATGACGTACAACAACGCGTCACCTTTGGCACTTCTGGGCACAGAGGCTGCGCTTTTAATG
GCAGTTTTAACCAACAACACATTTGGGCGATTACCCAAGCTGTGGTGGATTATCGCCAATCGGTGAATATCAATGGGCCG
TTGATCCTCGGGATTGACACCCATGCGTTATCCTACGCCGCTTATTTATCGGCAATTGAAGTGCTGGCGGCAAATAAAGT
CACAGTGCACATCCAGCAAAATGATGGTTTCACGCCAACACCAGTTGTGTCCCATGGGGTGATTTGCGCCAATCGCGAAG
CGAATATCACAGGTGCGCCTCTTTCTGATGGTTTGATTATCACGCCTTCCCACAATCCGCCTCAAGATGGCGGGATCAAA
TACAATCCACCCCATGGCGGACCAGCAGAAGGAAATATCACGGCTTGGATTGAGTCGCGTGCCAATGATTACTTGCGCCA
AGCGTTAGCTGGAGTGCAAAAATTAGCGTATGCCGAAGCGCTGGCCTCAGGCTATGTCAACGCCATTGATTTGATCACGC
CCTATGTGGCTGATTTAGAGAATGTTATCGATATGCAGGCGATTGCCAACGCTAAGCTGCGTATCGGTGTGGACCCGCTC
GGTGGTTCAGGGATTTTCTACTGGGCTCCGATTGCCGCGCGTTATGGGCTCGATATCACCTTAGTTAATGATAAAGTTGA
CCCAAGCTTTAGCTTTATGCCGCTCGATAAAGACGGCAAAATCCGCATGGATTGCTCGTCTCCCTATGCGATGGCTGGGT
TACTCGCCCATAAAGAATCTTATGATTTATGCCTTGGTAACGATCCTGACTATGACCGCCATGGCATTGTCTGCCCAGGT
ACCGGCTTGATGGATCCTAATCACTACCTTGCGGTCGCTATCGATTATTTACTGACACACAGACCGGATTGGAGCGATAG
CTTAGCCATAGGTAAAACCTTAGTATCGAGCGCGCTTATCGATAAAATCTGTGCTTTCCACGGCAAAAAATTACTCGAAG
TGCCTGTGGGATTTAAGTGGTTTGTCGATGGTTTAGCCGAAGCCACCATCGCCTTTGGCGGTGAAGAGAGCGCTGGTGCG
GCATTTTTACGCCGTGATGGCACAACGTGGTGCACGGATAAAGACGGCTTCATTTTAGGGTTACTTGCCGCAGAAATTCT
TGCGGTGACAGGTAAAACTCCAGGTCAACGCCATCAAGAGCTAGTAGAACAATTTGGCCAAAGTTTCTATAAGCGTATCG
ATAGCCCAATCAGTCTTGAAAACAAGGCCAAATTTGCGTTATTGAATGCAGAAACCTTAAATGCCACTGTGCTTGCGGGT
GAGGTAATCGAAAACGTGTTAACCCATGCGCCGGGCAATAATGCGGCCATTGGTGGCATCAAAGTGACTACGGCGAATGG
TTGGTTTGCCGCGCGTCCATCGGGCACGGAAGCGTTATTTAAGATCTACGGCGAGAGTTTTATCAGTGAGCAGCATTTAG
CTGAAATTATCAAAGATGCGCAGGCATTAATTGATAAGGCGCTGAACGCTTAA

Upstream 100 bases:

>100_bases
ATCGCCGAGCGCGTTTAATCTGCGGGTGAGCCATTTAATCAGCTATTGAGCTAAGTTTAACCATTGTTTTTAATTGTAGT
TGAGTGCAGGAGAGCCATAG

Downstream 100 bases:

>100_bases
TGCAGCAGTAGGTTTATAAAGTATAAAAAAACAAACGCACTCAGATTTGAGTGCGTTTTTGTTTGTGTCTAATTCAGTTA
TGAGTAGTTGATCTCATGCT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAIHQRAGQIANQTDLVNIPKLMSHYYSITPNMDDVQQRVTFGTSGHRGCAFNGSFNQQHIWAITQAVVDYRQSVNINGP
LILGIDTHALSYAAYLSAIEVLAANKVTVHIQQNDGFTPTPVVSHGVICANREANITGAPLSDGLIITPSHNPPQDGGIK
YNPPHGGPAEGNITAWIESRANDYLRQALAGVQKLAYAEALASGYVNAIDLITPYVADLENVIDMQAIANAKLRIGVDPL
GGSGIFYWAPIAARYGLDITLVNDKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKESYDLCLGNDPDYDRHGIVCPG
TGLMDPNHYLAVAIDYLLTHRPDWSDSLAIGKTLVSSALIDKICAFHGKKLLEVPVGFKWFVDGLAEATIAFGGEESAGA
AFLRRDGTTWCTDKDGFILGLLAAEILAVTGKTPGQRHQELVEQFGQSFYKRIDSPISLENKAKFALLNAETLNATVLAG
EVIENVLTHAPGNNAAIGGIKVTTANGWFAARPSGTEALFKIYGESFISEQHLAEIIKDAQALIDKALNA

Sequences:

>Translated_550_residues
MAIHQRAGQIANQTDLVNIPKLMSHYYSITPNMDDVQQRVTFGTSGHRGCAFNGSFNQQHIWAITQAVVDYRQSVNINGP
LILGIDTHALSYAAYLSAIEVLAANKVTVHIQQNDGFTPTPVVSHGVICANREANITGAPLSDGLIITPSHNPPQDGGIK
YNPPHGGPAEGNITAWIESRANDYLRQALAGVQKLAYAEALASGYVNAIDLITPYVADLENVIDMQAIANAKLRIGVDPL
GGSGIFYWAPIAARYGLDITLVNDKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKESYDLCLGNDPDYDRHGIVCPG
TGLMDPNHYLAVAIDYLLTHRPDWSDSLAIGKTLVSSALIDKICAFHGKKLLEVPVGFKWFVDGLAEATIAFGGEESAGA
AFLRRDGTTWCTDKDGFILGLLAAEILAVTGKTPGQRHQELVEQFGQSFYKRIDSPISLENKAKFALLNAETLNATVLAG
EVIENVLTHAPGNNAAIGGIKVTTANGWFAARPSGTEALFKIYGESFISEQHLAEIIKDAQALIDKALNA
>Mature_549_residues
AIHQRAGQIANQTDLVNIPKLMSHYYSITPNMDDVQQRVTFGTSGHRGCAFNGSFNQQHIWAITQAVVDYRQSVNINGPL
ILGIDTHALSYAAYLSAIEVLAANKVTVHIQQNDGFTPTPVVSHGVICANREANITGAPLSDGLIITPSHNPPQDGGIKY
NPPHGGPAEGNITAWIESRANDYLRQALAGVQKLAYAEALASGYVNAIDLITPYVADLENVIDMQAIANAKLRIGVDPLG
GSGIFYWAPIAARYGLDITLVNDKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKESYDLCLGNDPDYDRHGIVCPGT
GLMDPNHYLAVAIDYLLTHRPDWSDSLAIGKTLVSSALIDKICAFHGKKLLEVPVGFKWFVDGLAEATIAFGGEESAGAA
FLRRDGTTWCTDKDGFILGLLAAEILAVTGKTPGQRHQELVEQFGQSFYKRIDSPISLENKAKFALLNAETLNATVLAGE
VIENVLTHAPGNNAAIGGIKVTTANGWFAARPSGTEALFKIYGESFISEQHLAEIIKDAQALIDKALNA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=504, Percent_Identity=23.2142857142857, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI133922562, Length=395, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21361621, Length=547, Percent_Identity=23.5831809872029, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786904, Length=548, Percent_Identity=56.3868613138686, Blast_Score=633, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=440, Percent_Identity=26.5909090909091, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17864244, Length=436, Percent_Identity=23.8532110091743, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59183; Mature: 59052

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHQRAGQIANQTDLVNIPKLMSHYYSITPNMDDVQQRVTFGTSGHRGCAFNGSFNQQH
CCCCHHHCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCEEECCCCCCHH
IWAITQAVVDYRQSVNINGPLILGIDTHALSYAAYLSAIEVLAANKVTVHIQQNDGFTPT
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
PVVSHGVICANREANITGAPLSDGLIITPSHNPPQDGGIKYNPPHGGPAEGNITAWIESR
CHHHCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEHHH
ANDYLRQALAGVQKLAYAEALASGYVNAIDLITPYVADLENVIDMQAIANAKLRIGVDPL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GGSGIFYWAPIAARYGLDITLVNDKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKES
CCCCEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCC
YDLCLGNDPDYDRHGIVCPGTGLMDPNHYLAVAIDYLLTHRPDWSDSLAIGKTLVSSALI
CCEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
DKICAFHGKKLLEVPVGFKWFVDGLAEATIAFGGEESAGAAFLRRDGTTWCTDKDGFILG
HHHHHHCCCEEEECCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCEEEECCCCHHHH
LLAAEILAVTGKTPGQRHQELVEQFGQSFYKRIDSPISLENKAKFALLNAETLNATVLAG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHH
EVIENVLTHAPGNNAAIGGIKVTTANGWFAARPSGTEALFKIYGESFISEQHLAEIIKDA
HHHHHHHHCCCCCCCEECCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QALIDKALNA
HHHHHHHHCC
>Mature Secondary Structure 
AIHQRAGQIANQTDLVNIPKLMSHYYSITPNMDDVQQRVTFGTSGHRGCAFNGSFNQQH
CCCHHHCCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCEEECCCCCCHH
IWAITQAVVDYRQSVNINGPLILGIDTHALSYAAYLSAIEVLAANKVTVHIQQNDGFTPT
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
PVVSHGVICANREANITGAPLSDGLIITPSHNPPQDGGIKYNPPHGGPAEGNITAWIESR
CHHHCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEHHH
ANDYLRQALAGVQKLAYAEALASGYVNAIDLITPYVADLENVIDMQAIANAKLRIGVDPL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GGSGIFYWAPIAARYGLDITLVNDKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKES
CCCCEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCC
YDLCLGNDPDYDRHGIVCPGTGLMDPNHYLAVAIDYLLTHRPDWSDSLAIGKTLVSSALI
CCEEECCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
DKICAFHGKKLLEVPVGFKWFVDGLAEATIAFGGEESAGAAFLRRDGTTWCTDKDGFILG
HHHHHHCCCEEEECCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCEEEECCCCHHHH
LLAAEILAVTGKTPGQRHQELVEQFGQSFYKRIDSPISLENKAKFALLNAETLNATVLAG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHH
EVIENVLTHAPGNNAAIGGIKVTTANGWFAARPSGTEALFKIYGESFISEQHLAEIIKDA
HHHHHHHHCCCCCCCEECCEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QALIDKALNA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]