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The map label for this gene is hlyB [H]

Identifier: 126174150

GI number: 126174150

Start: 2238093

End: 2239688

Strand: Direct

Name: hlyB [H]

Synonym: Sbal_1924

Alternate gene names: 126174150

Gene position: 2238093-2239688 (Clockwise)

Preceding gene: 126174149

Following gene: 126174156

Centisome position: 43.65

GC content: 46.87

Gene sequence:

>1596_bases
GTGGACAGTTTAAGTATCAGCGTCGCCGACGAAGTCGCCTATTACACTGAGTTAAATAAGTTACTATTGGCGATAGTCGA
TGAAACCGCAAAAACTGGCGCCAACCAAGAAATCGCCATCCAAGCTGCTGCCTTTAGTGCTTTTTTGCAATTAAAGGAGA
GGGCGGGGATAGAAAGGGCGGTGTTAAGTTCAACCTTCGGCCAAGCCGGATTTAAGCCTAAGGTTTACGCTAAATTTATT
ACCTTAGTGTCGGAGCAAAATACCTATCAACAACGGTTCTTAGCATTAGCAGACTCAGATTTGTTAGCGGCATTTAACCG
TTTGCGAAGTTCTGCTGCAATGCACGATGTTGAGTTGTTACGTCAGCTTGCATTTGAACAAGACAATCAAAAAATCCAGC
AACAAAGTCCCGAAGATTGGTACAGTAAATCAACCGTACGGATTGAGCTATTACGTGAGTTTGAACAGCAAGTCTCGGCA
GATTTACTCAATACCAACCATGTAAGATTATCCTTAGCAAATGAAAAAATGTTCTTAGTGCTCGCGACCTTAATCTCAGT
ATTGGCGATAGTGTTGATATTGAGTTTATCCGTGATCCGCTACTTGCACGACAGCGTGCATCATTTATATTCGACCATTA
CGCAAGCCCGTAAACATTACGATTTAAGCGTGCGTTTGACTCAAACAAGCTCGGATGAGTTTGGTGAACTTGCCATCGCC
TTTAACGACATGATGAGTGATTTTGAAAAGGTGATCCTGCATGTGCGTTCCAGCGGCGCAAAACTGCAACAAGCCGTGGC
ACAAATGGATGTATGTACTCACTCCATGGAACAAGATGTAATGGCGGGTCACAGCGAGGCAGAGCAAGTGGCCTCGGCGA
TGACTGAAATGAGTGCGACAGTGGCCGAGATTGCCAGCAATGCGGTGCAGGCATCCGAAGCGTCTTCCGCCGCCAATATT
GAGGCAAAAGAAGGTAACCTCGAAGTCGGCCGAACCAGTAAAGCGATCAAAGCCTTAGCCGATGATATCAGTGGAGCCTC
TAAAGCCATCAACGACTTAGACCGTGAAATTCATGGCATAGTGGTTGTGCTTGAGGTGATCAGCAGTATTGCAGAGCAAA
CCAATCTACTCGCACTCAATGCCGCGATTGAAGCCGCGCGAGCAGGGGAAATGGGCCGCGGCTTTGCCGTTGTTGCCGAT
GAAGTCCGCAGTTTGGCACAGCGCTCACAAACCTCGACCTCTGATATTAAAAACATGACAGATAGATTGAAGGCAGGGGC
GAGCATTGCGGTAAAAGCCATGGACAGAGGCTTGGCGCAGGCGAATAACAGTGTTCATGAAGCCGAGCAAGCGGGCGTTG
AACTGAAACGGATTGTGGAGCAAGTCGACATTATTGATCGCATGAACGAGCAAATTGCCACCGCAACCCACGAGCAATCG
GCCGTATCCGAAGACGTAAACCGTAATGCATTCAAGATCAGTGAGATTTACCTCAATACCCAAAGGATCTCCGATGAGCT
TAGGGAACTGACTAAAGCCCTGACATATGACGCGAATTTAATGTCAAAAGAAGTACACAAATTTACCGTCAATTAA

Upstream 100 bases:

>100_bases
AGTTAACGGATACGCAGCTTAGTCTCTATCAGCAATATTTGCTCCTAAACTTAAGGAACTTAATTCACAGTTAGGGCGAT
TAAATTCAATTCGCTCACAG

Downstream 100 bases:

>100_bases
CAACATAAAACGGTGAAAAGATTCAGGAAATGACGGCGGTTTGTTTAGCAATTGCGCAACCGCCTGAAACTGAGTCTTTT
TTACTTGACCCCCTTTAGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MDSLSISVADEVAYYTELNKLLLAIVDETAKTGANQEIAIQAAAFSAFLQLKERAGIERAVLSSTFGQAGFKPKVYAKFI
TLVSEQNTYQQRFLALADSDLLAAFNRLRSSAAMHDVELLRQLAFEQDNQKIQQQSPEDWYSKSTVRIELLREFEQQVSA
DLLNTNHVRLSLANEKMFLVLATLISVLAIVLILSLSVIRYLHDSVHHLYSTITQARKHYDLSVRLTQTSSDEFGELAIA
FNDMMSDFEKVILHVRSSGAKLQQAVAQMDVCTHSMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVQASEASSAANI
EAKEGNLEVGRTSKAIKALADDISGASKAINDLDREIHGIVVVLEVISSIAEQTNLLALNAAIEAARAGEMGRGFAVVAD
EVRSLAQRSQTSTSDIKNMTDRLKAGASIAVKAMDRGLAQANNSVHEAEQAGVELKRIVEQVDIIDRMNEQIATATHEQS
AVSEDVNRNAFKISEIYLNTQRISDELRELTKALTYDANLMSKEVHKFTVN

Sequences:

>Translated_531_residues
MDSLSISVADEVAYYTELNKLLLAIVDETAKTGANQEIAIQAAAFSAFLQLKERAGIERAVLSSTFGQAGFKPKVYAKFI
TLVSEQNTYQQRFLALADSDLLAAFNRLRSSAAMHDVELLRQLAFEQDNQKIQQQSPEDWYSKSTVRIELLREFEQQVSA
DLLNTNHVRLSLANEKMFLVLATLISVLAIVLILSLSVIRYLHDSVHHLYSTITQARKHYDLSVRLTQTSSDEFGELAIA
FNDMMSDFEKVILHVRSSGAKLQQAVAQMDVCTHSMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVQASEASSAANI
EAKEGNLEVGRTSKAIKALADDISGASKAINDLDREIHGIVVVLEVISSIAEQTNLLALNAAIEAARAGEMGRGFAVVAD
EVRSLAQRSQTSTSDIKNMTDRLKAGASIAVKAMDRGLAQANNSVHEAEQAGVELKRIVEQVDIIDRMNEQIATATHEQS
AVSEDVNRNAFKISEIYLNTQRISDELRELTKALTYDANLMSKEVHKFTVN
>Mature_531_residues
MDSLSISVADEVAYYTELNKLLLAIVDETAKTGANQEIAIQAAAFSAFLQLKERAGIERAVLSSTFGQAGFKPKVYAKFI
TLVSEQNTYQQRFLALADSDLLAAFNRLRSSAAMHDVELLRQLAFEQDNQKIQQQSPEDWYSKSTVRIELLREFEQQVSA
DLLNTNHVRLSLANEKMFLVLATLISVLAIVLILSLSVIRYLHDSVHHLYSTITQARKHYDLSVRLTQTSSDEFGELAIA
FNDMMSDFEKVILHVRSSGAKLQQAVAQMDVCTHSMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVQASEASSAANI
EAKEGNLEVGRTSKAIKALADDISGASKAINDLDREIHGIVVVLEVISSIAEQTNLLALNAAIEAARAGEMGRGFAVVAD
EVRSLAQRSQTSTSDIKNMTDRLKAGASIAVKAMDRGLAQANNSVHEAEQAGVELKRIVEQVDIIDRMNEQIATATHEQS
AVSEDVNRNAFKISEIYLNTQRISDELRELTKALTYDANLMSKEVHKFTVN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=313, Percent_Identity=30.0319488817891, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787690, Length=317, Percent_Identity=30.9148264984227, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=33.4710743801653, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=344, Percent_Identity=27.6162790697674, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58257; Mature: 58257

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLSISVADEVAYYTELNKLLLAIVDETAKTGANQEIAIQAAAFSAFLQLKERAGIERA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCHHHH
VLSSTFGQAGFKPKVYAKFITLVSEQNTYQQRFLALADSDLLAAFNRLRSSAAMHDVELL
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLAFEQDNQKIQQQSPEDWYSKSTVRIELLREFEQQVSADLLNTNHVRLSLANEKMFLV
HHHHHCCHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
LATLISVLAIVLILSLSVIRYLHDSVHHLYSTITQARKHYDLSVRLTQTSSDEFGELAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
FNDMMSDFEKVILHVRSSGAKLQQAVAQMDVCTHSMEQDVMAGHSEAEQVASAMTEMSAT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAEIASNAVQASEASSAANIEAKEGNLEVGRTSKAIKALADDISGASKAINDLDREIHGI
HHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VVVLEVISSIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
DRLKAGASIAVKAMDRGLAQANNSVHEAEQAGVELKRIVEQVDIIDRMNEQIATATHEQS
HHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSEDVNRNAFKISEIYLNTQRISDELRELTKALTYDANLMSKEVHKFTVN
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSLSISVADEVAYYTELNKLLLAIVDETAKTGANQEIAIQAAAFSAFLQLKERAGIERA
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCHHHH
VLSSTFGQAGFKPKVYAKFITLVSEQNTYQQRFLALADSDLLAAFNRLRSSAAMHDVELL
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RQLAFEQDNQKIQQQSPEDWYSKSTVRIELLREFEQQVSADLLNTNHVRLSLANEKMFLV
HHHHHCCHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
LATLISVLAIVLILSLSVIRYLHDSVHHLYSTITQARKHYDLSVRLTQTSSDEFGELAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
FNDMMSDFEKVILHVRSSGAKLQQAVAQMDVCTHSMEQDVMAGHSEAEQVASAMTEMSAT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAEIASNAVQASEASSAANIEAKEGNLEVGRTSKAIKALADDISGASKAINDLDREIHGI
HHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VVVLEVISSIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
DRLKAGASIAVKAMDRGLAQANNSVHEAEQAGVELKRIVEQVDIIDRMNEQIATATHEQS
HHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSEDVNRNAFKISEIYLNTQRISDELRELTKALTYDANLMSKEVHKFTVN
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]