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The map label for this gene is yfbK [C]

Identifier: 126174069

GI number: 126174069

Start: 2140893

End: 2143208

Strand: Direct

Name: yfbK [C]

Synonym: Sbal_1843

Alternate gene names: 126174069

Gene position: 2140893-2143208 (Clockwise)

Preceding gene: 126174068

Following gene: 126174070

Centisome position: 41.75

GC content: 50.22

Gene sequence:

>2316_bases
ATGATCACAGGGAAAAGGGTAAAAGAAATCAGCGAAAGCTTAGCGATATTAATGATCAGTGTCGCCGTATGTTGGGGCTT
GCCCTTTGTGGCATTAGCCTCACCCAATAGCACGGGCACATTGTCTGAGCCGCAGAATATTGCCTCGGCGCTGGTCGGCC
AAAATACTGCTCAAAGTACGGCAGAATCACAGGTCATTAATTACGATGACATTACTCAGGGTTTGTTGCTTTATCGTCAG
CCGAGCGGCGCTTGGGTGCCATCTTTGCCACTCGATACACAAGTGTCGATGCAAGTCTCTGGCTTAAGTAATCGCGTGAG
TGTGAAGCAGGTTTTTCGCAATAACACTGAATTTGTGTTGAATGGGCAATATCTGTTCCCGCTGCCCAATGAGGCCGCGG
TGGATTCGCTGCGATTACATATCGGCCAAAGGGTCATCGAAGGGCAAATTCATCCTAAGGCCGAGGCTAAGCAGATTTTT
GAGCAAGCCAAAGCGGAGGGCAAACGCGCCAGCTTAGTGAGCCAAGAGCGGCCGAATATGTTCACGACCGAAGTGGCCAA
CCTAGCACCGCAGGAAGAGTTGATTGTCGAAATCAGCTATCAGGAGAATATCAAATATGAAGACGGCTTATTTAGCCTAC
GTTTTCCGCTGGTGGTCGCGCCTCGGTATATCCCGGGCTTAACCTCTGACGCAAGTGCTAGCGATTCAAATAATCCTATA
GCACAGAGCAGCCAATCGAGCCGAGTGACCAGCTCGCAGGTGTTTGATGCCGACCGGATTGTGGCGCCTGTGCGGGACGG
CGCCAGTGGACGCGATCCTGTGCTCAAGGCGGACATTCAAGTCTTGCTGGCAAAGGGGGTTGATAAGGCGTCAATTGAGA
GTCCTTACCATGACATCAAACTCAAGCAAACCAATAGCGGCGTCGATGTTTCACTGGCACAACGCGTGCCTGCCAATCGT
GACTTTGTACTGCAATGGCGCGTACAGCAGGGTACGAGTCCAATGGCTTGGGTGTTTAATCAACAGGGTAAGACCCATAA
ACCCGATGGCGATAATTTGTCTCAGGACACGCTTGAAACCAGCAAAGCTAACGGCGTAAATGAAGATAATTATAGTCTCG
TCATGGTGTTGCCTCCTAAGGTCGAAAAGAGCACCCAACCAAGTTTGCCCCGTGAATTAATTTTGGTGATTGATACTTCG
GGCTCTATGGCGGGGGATTCTATCGTTCAAGCCAAAAATGCACTGCTTTATGCATTAAAAGGACTCAAGCCCGAGGACAG
TTTTAACATTATCGAATTTAACTCCAGTCTGTCTCAGTTTTCAGCGACACCATTACCTGCGACTTCGTCTAATTTGTCCC
GCGCCCGTCAATTTGTGAGCCGTTTACAAGCCGATGGTGGCACTGAAATGGCGCTGGCACTGGATGCGGCCTTGCCAAAA
TCTTTGGGCAGTGCCCCGTCCGATGCTGTGCAGCCTTTGCGCCAAGTGATCTTTATGACCGACGGCTCTGTGGGCAATGA
GCAAGCCTTGTTCGATTTGATCCGCTATCAAATCGGAGAGAGCCGCTTATTTACTGTCGGCATAGGCTCAGCGCCTAATT
CTCACTTTATGCAAAGGGCGGCAGAGCTGGGTCGTGGCACTTTTACTTATATTGGCAAAGTGGATGAAGTCGGCGAGAAG
ATCAGCGCCTTGCTGAGCAAAATTCAATATCCCTTATTAACCGATATTCAAGTGCGTTTTGATGATGGCAGTGTGCCCGA
TTACTGGCCATCACCGATTGCCGATCTGTATCGCGGCGAGCCTGTGCTCGTAAGTCTAAAACGCAGCGCCCGTGAGCCGC
AGGAATTAGTGATCTTAGGTCGCCAAGGGCATAAAAACTGGCAACAGTCGTTATCGCTTCAGGACAACTCAGCGGGACTT
ATCACCAATCAAGGTGCGGGTTTAGATTTACTGTGGGCGCGTAAACAGATTGGTGCATTGGAGCTGAGTAAAAATGGCGC
AAATGATGACAAGGTAAAGCAGCAAGTCACGGCTTTGTCGATGAATTATCACTTAGTCAGCGCTTATACCAGCTTAGTGG
CGGTGGACTTAACCCCCATAGATTCAACTGCAATGAGCCGCGATGCAGTGGTGCGTCAGCACTTGCCCTTAGGTTGGCAG
CCTTTTGGTGCCTTGCCACAAACTGCGACCTCGAGCCGTTTGGATATGTTATTGGGTGCGCTTACCTTGCTGCTGGCCTT
GGTACTTATGGGATCGATTCTGCGACAAAAATGTGAAGAGAAGGCAGCCATGATGGCGCTTGCCTGTCATCGATGA

Upstream 100 bases:

>100_bases
GATGTTAGTCGTCTATTCTAAGCCGTCAATTTAGAACATTCATTTTAACGACTGCGAACGTCAGTCCATATTAGTTAATA
GAAAGAAGGAAGCCTTTGTG

Downstream 100 bases:

>100_bases
ACCAATGAATCATGAACGACGAGTAAAGCCCGATGAGCAAAGGCAGAACGCAGCGATTTTTAGTGGTGGGATTATTTTTA
ATTGGCGCAACATTGTTAGG

Product: vault protein inter-alpha-trypsin subunit

Products: NA

Alternate protein names: Von Willebrand Factor Type A Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin; Inter-Alpha-Trypsin Inhibitor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain Protein; Von Willebrand Factor Type A; Cell Wall Anchor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain-Containing Protein; Von Willebrand Factor Type A Domain Protein; LPXTG-Motif Cell Wall Anchor Domain-Containing Protein; Transmembrane Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; Vault Protein Inter-Alpha-Trypsin Domain; Protein ContAining A Von Willebrand Factor Type A Domain; Inter-Alpha-Trypsin Inhibitor Domain Protein; Von Willebrand Factor

Number of amino acids: Translated: 771; Mature: 771

Protein sequence:

>771_residues
MITGKRVKEISESLAILMISVAVCWGLPFVALASPNSTGTLSEPQNIASALVGQNTAQSTAESQVINYDDITQGLLLYRQ
PSGAWVPSLPLDTQVSMQVSGLSNRVSVKQVFRNNTEFVLNGQYLFPLPNEAAVDSLRLHIGQRVIEGQIHPKAEAKQIF
EQAKAEGKRASLVSQERPNMFTTEVANLAPQEELIVEISYQENIKYEDGLFSLRFPLVVAPRYIPGLTSDASASDSNNPI
AQSSQSSRVTSSQVFDADRIVAPVRDGASGRDPVLKADIQVLLAKGVDKASIESPYHDIKLKQTNSGVDVSLAQRVPANR
DFVLQWRVQQGTSPMAWVFNQQGKTHKPDGDNLSQDTLETSKANGVNEDNYSLVMVLPPKVEKSTQPSLPRELILVIDTS
GSMAGDSIVQAKNALLYALKGLKPEDSFNIIEFNSSLSQFSATPLPATSSNLSRARQFVSRLQADGGTEMALALDAALPK
SLGSAPSDAVQPLRQVIFMTDGSVGNEQALFDLIRYQIGESRLFTVGIGSAPNSHFMQRAAELGRGTFTYIGKVDEVGEK
ISALLSKIQYPLLTDIQVRFDDGSVPDYWPSPIADLYRGEPVLVSLKRSAREPQELVILGRQGHKNWQQSLSLQDNSAGL
ITNQGAGLDLLWARKQIGALELSKNGANDDKVKQQVTALSMNYHLVSAYTSLVAVDLTPIDSTAMSRDAVVRQHLPLGWQ
PFGALPQTATSSRLDMLLGALTLLLALVLMGSILRQKCEEKAAMMALACHR

Sequences:

>Translated_771_residues
MITGKRVKEISESLAILMISVAVCWGLPFVALASPNSTGTLSEPQNIASALVGQNTAQSTAESQVINYDDITQGLLLYRQ
PSGAWVPSLPLDTQVSMQVSGLSNRVSVKQVFRNNTEFVLNGQYLFPLPNEAAVDSLRLHIGQRVIEGQIHPKAEAKQIF
EQAKAEGKRASLVSQERPNMFTTEVANLAPQEELIVEISYQENIKYEDGLFSLRFPLVVAPRYIPGLTSDASASDSNNPI
AQSSQSSRVTSSQVFDADRIVAPVRDGASGRDPVLKADIQVLLAKGVDKASIESPYHDIKLKQTNSGVDVSLAQRVPANR
DFVLQWRVQQGTSPMAWVFNQQGKTHKPDGDNLSQDTLETSKANGVNEDNYSLVMVLPPKVEKSTQPSLPRELILVIDTS
GSMAGDSIVQAKNALLYALKGLKPEDSFNIIEFNSSLSQFSATPLPATSSNLSRARQFVSRLQADGGTEMALALDAALPK
SLGSAPSDAVQPLRQVIFMTDGSVGNEQALFDLIRYQIGESRLFTVGIGSAPNSHFMQRAAELGRGTFTYIGKVDEVGEK
ISALLSKIQYPLLTDIQVRFDDGSVPDYWPSPIADLYRGEPVLVSLKRSAREPQELVILGRQGHKNWQQSLSLQDNSAGL
ITNQGAGLDLLWARKQIGALELSKNGANDDKVKQQVTALSMNYHLVSAYTSLVAVDLTPIDSTAMSRDAVVRQHLPLGWQ
PFGALPQTATSSRLDMLLGALTLLLALVLMGSILRQKCEEKAAMMALACHR
>Mature_771_residues
MITGKRVKEISESLAILMISVAVCWGLPFVALASPNSTGTLSEPQNIASALVGQNTAQSTAESQVINYDDITQGLLLYRQ
PSGAWVPSLPLDTQVSMQVSGLSNRVSVKQVFRNNTEFVLNGQYLFPLPNEAAVDSLRLHIGQRVIEGQIHPKAEAKQIF
EQAKAEGKRASLVSQERPNMFTTEVANLAPQEELIVEISYQENIKYEDGLFSLRFPLVVAPRYIPGLTSDASASDSNNPI
AQSSQSSRVTSSQVFDADRIVAPVRDGASGRDPVLKADIQVLLAKGVDKASIESPYHDIKLKQTNSGVDVSLAQRVPANR
DFVLQWRVQQGTSPMAWVFNQQGKTHKPDGDNLSQDTLETSKANGVNEDNYSLVMVLPPKVEKSTQPSLPRELILVIDTS
GSMAGDSIVQAKNALLYALKGLKPEDSFNIIEFNSSLSQFSATPLPATSSNLSRARQFVSRLQADGGTEMALALDAALPK
SLGSAPSDAVQPLRQVIFMTDGSVGNEQALFDLIRYQIGESRLFTVGIGSAPNSHFMQRAAELGRGTFTYIGKVDEVGEK
ISALLSKIQYPLLTDIQVRFDDGSVPDYWPSPIADLYRGEPVLVSLKRSAREPQELVILGRQGHKNWQQSLSLQDNSAGL
ITNQGAGLDLLWARKQIGALELSKNGANDDKVKQQVTALSMNYHLVSAYTSLVAVDLTPIDSTAMSRDAVVRQHLPLGWQ
PFGALPQTATSSRLDMLLGALTLLLALVLMGSILRQKCEEKAAMMALACHR

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI112789550, Length=637, Percent_Identity=21.8210361067504, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI262050538, Length=328, Percent_Identity=26.8292682926829, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI31542984, Length=328, Percent_Identity=26.8292682926829, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI38195080, Length=522, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI194306644, Length=522, Percent_Identity=24.1379310344828, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI133925809, Length=328, Percent_Identity=27.1341463414634, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI70778918, Length=326, Percent_Identity=23.0061349693252, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI38348336, Length=339, Percent_Identity=25.6637168141593, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI153945711, Length=336, Percent_Identity=21.4285714285714, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI153945780, Length=336, Percent_Identity=21.4285714285714, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI49355778, Length=336, Percent_Identity=21.4285714285714, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI210147462, Length=572, Percent_Identity=21.8531468531469, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI261878614, Length=328, Percent_Identity=23.4756097560976, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI156119625, Length=328, Percent_Identity=23.4756097560976, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI261878618, Length=327, Percent_Identity=23.5474006116208, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI261878616, Length=327, Percent_Identity=23.5474006116208, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 83760; Mature: 83760

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITGKRVKEISESLAILMISVAVCWGLPFVALASPNSTGTLSEPQNIASALVGQNTAQST
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHH
AESQVINYDDITQGLLLYRQPSGAWVPSLPLDTQVSMQVSGLSNRVSVKQVFRNNTEFVL
HHHCCCCHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEE
NGQYLFPLPNEAAVDSLRLHIGQRVIEGQIHPKAEAKQIFEQAKAEGKRASLVSQERPNM
ECEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCC
FTTEVANLAPQEELIVEISYQENIKYEDGLFSLRFPLVVAPRYIPGLTSDASASDSNNPI
HHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCEEECCHHCCCCCCCCCCCCCCCCC
AQSSQSSRVTSSQVFDADRIVAPVRDGASGRDPVLKADIQVLLAKGVDKASIESPYHDIK
CCCCCCCCCCHHHHCCCHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCEE
LKQTNSGVDVSLAQRVPANRDFVLQWRVQQGTSPMAWVFNQQGKTHKPDGDNLSQDTLET
EEECCCCCCEEHHHHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
SKANGVNEDNYSLVMVLPPKVEKSTQPSLPRELILVIDTSGSMAGDSIVQAKNALLYALK
HHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
GLKPEDSFNIIEFNSSLSQFSATPLPATSSNLSRARQFVSRLQADGGTEMALALDAALPK
CCCCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
SLGSAPSDAVQPLRQVIFMTDGSVGNEQALFDLIRYQIGESRLFTVGIGSAPNSHFMQRA
HHCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
AELGRGTFTYIGKVDEVGEKISALLSKIQYPLLTDIQVRFDDGSVPDYWPSPIADLYRGE
HHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCC
PVLVSLKRSAREPQELVILGRQGHKNWQQSLSLQDNSAGLITNQGAGLDLLWARKQIGAL
CEEEEECHHCCCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCCCCEEEEEHHHHCCEE
ELSKNGANDDKVKQQVTALSMNYHLVSAYTSLVAVDLTPIDSTAMSRDAVVRQHLPLGWQ
EECCCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCC
PFGALPQTATSSRLDMLLGALTLLLALVLMGSILRQKCEEKAAMMALACHR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITGKRVKEISESLAILMISVAVCWGLPFVALASPNSTGTLSEPQNIASALVGQNTAQST
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHH
AESQVINYDDITQGLLLYRQPSGAWVPSLPLDTQVSMQVSGLSNRVSVKQVFRNNTEFVL
HHHCCCCHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEE
NGQYLFPLPNEAAVDSLRLHIGQRVIEGQIHPKAEAKQIFEQAKAEGKRASLVSQERPNM
ECEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCC
FTTEVANLAPQEELIVEISYQENIKYEDGLFSLRFPLVVAPRYIPGLTSDASASDSNNPI
HHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCEEECCHHCCCCCCCCCCCCCCCCC
AQSSQSSRVTSSQVFDADRIVAPVRDGASGRDPVLKADIQVLLAKGVDKASIESPYHDIK
CCCCCCCCCCHHHHCCCHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCCCCEE
LKQTNSGVDVSLAQRVPANRDFVLQWRVQQGTSPMAWVFNQQGKTHKPDGDNLSQDTLET
EEECCCCCCEEHHHHCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
SKANGVNEDNYSLVMVLPPKVEKSTQPSLPRELILVIDTSGSMAGDSIVQAKNALLYALK
HHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
GLKPEDSFNIIEFNSSLSQFSATPLPATSSNLSRARQFVSRLQADGGTEMALALDAALPK
CCCCCCCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
SLGSAPSDAVQPLRQVIFMTDGSVGNEQALFDLIRYQIGESRLFTVGIGSAPNSHFMQRA
HHCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
AELGRGTFTYIGKVDEVGEKISALLSKIQYPLLTDIQVRFDDGSVPDYWPSPIADLYRGE
HHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHCCC
PVLVSLKRSAREPQELVILGRQGHKNWQQSLSLQDNSAGLITNQGAGLDLLWARKQIGAL
CEEEEECHHCCCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCCCCEEEEEHHHHCCEE
ELSKNGANDDKVKQQVTALSMNYHLVSAYTSLVAVDLTPIDSTAMSRDAVVRQHLPLGWQ
EECCCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCC
PFGALPQTATSSRLDMLLGALTLLLALVLMGSILRQKCEEKAAMMALACHR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA