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The map label for this gene is grxD [H]

Identifier: 126174010

GI number: 126174010

Start: 2076651

End: 2076983

Strand: Direct

Name: grxD [H]

Synonym: Sbal_1783

Alternate gene names: 126174010

Gene position: 2076651-2076983 (Clockwise)

Preceding gene: 126174005

Following gene: 126174012

Centisome position: 40.5

GC content: 43.84

Gene sequence:

>333_bases
ATGGAAACAGTAGAGAAAATTAAGCAGCAGATCACGGAAAACCCTATCATTGTTTATATGAAAGGCTCTCCTAAGTTGCC
TAGCTGTGGCTTCTCGTCACAGGTAGCTCAGATCATGATTAACTGCGGTGAGCAGTTTGCATTCGTGGATATTCTTCAGC
ATCCAGACATTCGCGCAGAATTACCTAAGTTTGCTAACTGGCCGACTTTCCCACAATTGTGGATTGAAGGTGAGTTGATC
GGTGGCTGTGATATCGTTGTGGACATGTTCCAAAAAGGCGAATTACAACCTTTGATCAAAGCCGCTGCCGCTAAGATCAA
GACTGAAGAATAA

Upstream 100 bases:

>100_bases
CAAATGTCGGCATAACCTTACAAACTGTGGGATTTTGTTCTGCCTCTAGCTGACGTACAATAGTCGCATTGAGTCAATGT
CATCCTACTTAGGAATCAAA

Downstream 100 bases:

>100_bases
GCGTTAATGCTTTTTTATAAGTATTAATGAAAAAGCCGCCATGATTAATATCACGGCGGCTTTTTTGTCGCTGTTTTTCA
AAGAGCTATCGCTAAAAAAA

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
METVEKIKQQITENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKFANWPTFPQLWIEGELI
GGCDIVVDMFQKGELQPLIKAAAAKIKTEE

Sequences:

>Translated_110_residues
METVEKIKQQITENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKFANWPTFPQLWIEGELI
GGCDIVVDMFQKGELQPLIKAAAAKIKTEE
>Mature_110_residues
METVEKIKQQITENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAELPKFANWPTFPQLWIEGELI
GGCDIVVDMFQKGELQPLIKAAAAKIKTEE

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=97, Percent_Identity=37.1134020618557, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=38.0434782608696, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787943, Length=108, Percent_Identity=73.1481481481482, Blast_Score=182, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71988153, Length=82, Percent_Identity=36.5853658536585, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556042, Length=98, Percent_Identity=31.6326530612245, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=80, Percent_Identity=38.75, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325198, Length=112, Percent_Identity=37.5, Blast_Score=95, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321022, Length=72, Percent_Identity=50, Blast_Score=87, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=81, Percent_Identity=44.4444444444444, Blast_Score=87, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24642023, Length=93, Percent_Identity=43.010752688172, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19921242, Length=97, Percent_Identity=36.0824742268041, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12321; Mature: 12321

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVEKIKQQITENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LPKFANWPTFPQLWIEGELIGGCDIVVDMFQKGELQPLIKAAAAKIKTEE
CCCCCCCCCCCCEEECCEEECCHHHHHHHHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
METVEKIKQQITENPIIVYMKGSPKLPSCGFSSQVAQIMINCGEQFAFVDILQHPDIRAE
CCHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
LPKFANWPTFPQLWIEGELIGGCDIVVDMFQKGELQPLIKAAAAKIKTEE
CCCCCCCCCCCCEEECCEEECCHHHHHHHHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]