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The map label for this gene is nhaB

Identifier: 126174004

GI number: 126174004

Start: 2068049

End: 2069650

Strand: Reverse

Name: nhaB

Synonym: Sbal_1777

Alternate gene names: 126174004

Gene position: 2069650-2068049 (Counterclockwise)

Preceding gene: 126174006

Following gene: 126174003

Centisome position: 40.36

GC content: 44.44

Gene sequence:

>1602_bases
ATGCCGGCGACAATGAGTCAGGCGTTTATTGGGAACTTCTTAGGAAATTCTCCTAAGTGGTACAAAACCGCAATACTGTC
ATTTTTAATTATCAATCCACTACTCTTTTTCTATGTCGACCCCTTCGTGGCCGGCTGGGTATTGGTGCTTGAATTTATTT
TTACCTTAGCAATGGCATTAAAATGTTATCCATTACAGCCTGGCGGATTATTAGCAATTGAAGCTGTCGCTATTGGCATG
ACATCGGCAAGCCAAGTCTTACATGAAATAGAAGCCAACCTCGAAGTATTATTACTCTTGGTGTTTATGGTCGCTGGTAT
TTATTTCATGAAGCAATTGCTGCTATTTGGCTTCACGAAAATTATTACCAAAGTGCGTTCTAAAGTTTTAGTGTCACTGA
TGTTTTGTTTGGCATCGGCGTTTTTATCTGCCTTCTTAGATGCGTTAACGGTTATTGCCGTGATTATCGCGGTCGCTGTG
GGTTTCTATTCTATTTACCACAAGGTCGCTTCTGGAAAAGATTTCGGTGCCGATCACGATCATACCTCCGAAGGTAAAAA
CGCTGCAGGCGAAGATCAGTTAAACGAAGAAGAACTCGGTGCATTCCGTGGCTTTCTGCGTAATCTGTTAATGCATGCGG
GTGTCGGTACTGCACTTGGCGGTGTATGTACTATGGTGGGAGAACCTCAAAACCTGATCATTGCCGCACAGGCCAATTGG
CAGTTCGGTGAATTCGCCGTACGTATGTCACCAGTTACAGTCCCAGTATTGATTTCTGGTATCTTAACCTGCTACTTAGT
TGAAAAGTTTGGCATTTTTGGTTATGGCGCTAAATTGCCAACGGCCGTTCATCGGATCTTATGTGAATATGCCGCCCATG
AAGATGCGCGCCGTACTAATAAAGACAACATGAAGTTAATCGTCCAAGCACTCGTGGGTGTCTGGTTAATCGCAGGTCTT
GCCTTGCATTTAGCTTCTGTGGGCTTAATTGGTCTTTCTGTGATTATTTTAACCACAGCCTTTAATGGCGTCACCGATGA
GCATGCCCTTGGTAAAGCCTTCGAAGAAGCACTGCCTTTTACCGCATTATTAGCGGTGTTCTTTGCGGTTGTTGGCGTGA
TTATCGATCAACACTTATTCGCCCCCGTTATCCAATGGGCACTGGGTTATGAAGGCAATACCCAATTAGTGATTTTCTAT
ATCGCCAACGGATTATTGTCTATGGTGAGTGATAACGTGTTCGTCGGCACTGTGTATATCAACGAAGTGAAGGCGGCATT
GATTAATGGCCAAATCACCCGTGATCAATTCGACTTACTGGCCGTTGCGATTAATACCGGAACTAACTTACCTTCGGTGG
CGACACCTAATGGTCAAGCGGCGTTCTTGTTCTTACTGACTTCAGCCTTAGCACCGCTGATCCGCTTATCCTATGGCAGA
ATGGTATGGATGGCATTGCCCTACACTATTGTGCTATCCATTGTGGGCGTTATGGCGATCCAAACGGGATTCTTAGAACA
AGCCACTCAATATTTCTATGATTCCCATACAATCATCCATCACAGTGCAAAAGAAGTGTTGGGCACAGTGTCTGGACATT
AA

Upstream 100 bases:

>100_bases
TCGTTACATTAGCTTTCTCTTTAGGCTAGACTGATTTAACAAACGCAGGTATTGATATTAAACACGTGCAATTTTTAACA
TAATTAGAAGAGAGGCTGCC

Downstream 100 bases:

>100_bases
TCTTCTCTATTGACTGAACTTTATTAAATAAGTAGAGTCCAAAAAACGCCCCATGTCTGAGGGCGTTTTTTGTTGATATG
GAGCTCACTTTGACTGTCAT

Product: sodium/proton antiporter

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaB

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MPATMSQAFIGNFLGNSPKWYKTAILSFLIINPLLFFYVDPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFGFTKIITKVRSKVLVSLMFCLASAFLSAFLDALTVIAVIIAVAV
GFYSIYHKVASGKDFGADHDHTSEGKNAAGEDQLNEEELGAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
QFGEFAVRMSPVTVPVLISGILTCYLVEKFGIFGYGAKLPTAVHRILCEYAAHEDARRTNKDNMKLIVQALVGVWLIAGL
ALHLASVGLIGLSVIILTTAFNGVTDEHALGKAFEEALPFTALLAVFFAVVGVIIDQHLFAPVIQWALGYEGNTQLVIFY
IANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
MVWMALPYTIVLSIVGVMAIQTGFLEQATQYFYDSHTIIHHSAKEVLGTVSGH

Sequences:

>Translated_533_residues
MPATMSQAFIGNFLGNSPKWYKTAILSFLIINPLLFFYVDPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFGFTKIITKVRSKVLVSLMFCLASAFLSAFLDALTVIAVIIAVAV
GFYSIYHKVASGKDFGADHDHTSEGKNAAGEDQLNEEELGAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
QFGEFAVRMSPVTVPVLISGILTCYLVEKFGIFGYGAKLPTAVHRILCEYAAHEDARRTNKDNMKLIVQALVGVWLIAGL
ALHLASVGLIGLSVIILTTAFNGVTDEHALGKAFEEALPFTALLAVFFAVVGVIIDQHLFAPVIQWALGYEGNTQLVIFY
IANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
MVWMALPYTIVLSIVGVMAIQTGFLEQATQYFYDSHTIIHHSAKEVLGTVSGH
>Mature_532_residues
PATMSQAFIGNFLGNSPKWYKTAILSFLIINPLLFFYVDPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGMT
SASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFGFTKIITKVRSKVLVSLMFCLASAFLSAFLDALTVIAVIIAVAVG
FYSIYHKVASGKDFGADHDHTSEGKNAAGEDQLNEEELGAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQ
FGEFAVRMSPVTVPVLISGILTCYLVEKFGIFGYGAKLPTAVHRILCEYAAHEDARRTNKDNMKLIVQALVGVWLIAGLA
LHLASVGLIGLSVIILTTAFNGVTDEHALGKAFEEALPFTALLAVFFAVVGVIIDQHLFAPVIQWALGYEGNTQLVIFYI
ANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRM
VWMALPYTIVLSIVGVMAIQTGFLEQATQYFYDSHTIIHHSAKEVLGTVSGH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons

COG id: COG3067

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaB Na(+)/H(+) (TC 2.A.34) antiporter family

Homologues:

Organism=Escherichia coli, GI1787435, Length=488, Percent_Identity=68.2377049180328, Blast_Score=641, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NHAB_SHEB2 (B8EAH3)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358425.1
- GeneID:   7087044
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2508
- HOGENOM:   HBG296776
- OMA:   CFLVEKF
- ProtClustDB:   PRK09547
- HAMAP:   MF_01599
- InterPro:   IPR004671
- TIGRFAMs:   TIGR00774

Pfam domain/function: PF06450 NhaB

EC number: NA

Molecular weight: Translated: 57641; Mature: 57509

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14b3af80)-; HASH(0x15ca6af4)-; HASH(0x15bb8344)-; HASH(0x1320ccb4)-; HASH(0x14d76d74)-; HASH(0x15dca680)-; HASH(0x15a4122c)-; HASH(0x15a14088)-; HASH(0x1509934c)-; HASH(0x151db6f4)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
PATMSQAFIGNFLGNSPKWYKTAILSFLIINPLLFFYVDPFVAGWVLVLEFIFTLAMAL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCYPLQPGGLLAIEAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFGFTK
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITKVRSKVLVSLMFCLASAFLSAFLDALTVIAVIIAVAVGFYSIYHKVASGKDFGADHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HTSEGKNAAGEDQLNEEELGAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCC
QFGEFAVRMSPVTVPVLISGILTCYLVEKFGIFGYGAKLPTAVHRILCEYAAHEDARRTN
CHHHEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
KDNMKLIVQALVGVWLIAGLALHLASVGLIGLSVIILTTAFNGVTDEHALGKAFEEALPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
TALLAVFFAVVGVIIDQHLFAPVIQWALGYEGNTQLVIFYIANGLLSMVSDNVFVGTVYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEH
NEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGR
HHHHHHHHCCCCCHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MVWMALPYTIVLSIVGVMAIQTGFLEQATQYFYDSHTIIHHSAKEVLGTVSGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3 Proton [Periplasm]; Na (I) [Cytoplasm] [C]

Specific reaction: 3 Proton [Periplasm] + 2 Na (I) [Cytoplasm] = 2 Na (I) [Periplasm] + 3 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA