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The map label for this gene is tolA [C]

Identifier: 126173974

GI number: 126173974

Start: 2029587

End: 2030615

Strand: Direct

Name: tolA [C]

Synonym: Sbal_1745

Alternate gene names: 126173974

Gene position: 2029587-2030615 (Clockwise)

Preceding gene: 126173973

Following gene: 126173975

Centisome position: 39.58

GC content: 47.23

Gene sequence:

>1029_bases
GTGGCAGATAAGTCAGATGTAACATTACCTCTGTCAATTTCAGCGGGTATTCATATTGGCGTGATAATTATTCTGGCGTT
GGGGATCGATTTCTCTCACAAACCTGAGCCTATGCAACAAGTTAGTGCGCCAGCGGTTAAAGCCGTGATGGTTGATCAGC
AAAAAGTCGCTAATCAAGTTGAGAAACTTAAGCAAGAAAAGCGTGATGCCGAGCGCCGTGAGCAAGAACGTCAAGCTGAG
CTTGAGCGCAAAGCGCAAGAAGCGAAGCAAGCGCGCGAACGTGAACAAGCTCAGATTAAACAGTTAGAGCAAGAACGTAA
GCAGCAAGAAATTGAAACCCAAAAGGCCAATGAAGCGACCAAGCTAGCCCAAGTGAAACAGCAGCAGGAAAAGGAAAAGG
CAGTTAAAGCCGAAGCCGACCGTAAGCTGAAAGAGCAGGAGCGTAAAGTCGCCGAAGATGCCGCGCAAAAAGCAGCAGAA
AAACGCAAAGTGGAAGAAGCCGCTGCAGCGAAAGCGGAAAGTGACCGTAAGCTAAAGGAGGCAGAAGCTAAGGCCAAAGC
TGAAAAAGCCAAGGCAGATGCAGATGCGAAAGCCGAAGCTAAAGCTAAAGCCAAAGCAGATGCTAAAGCTAAAGCGGATG
CTAAGGCCAAAGCCGATGCTGAAGCCAAAGCCCGAGCTCAGCAGGAGCAAGAAATGGCTGATGCATTAGCGGCGGAGCAG
GCGGCGTTGTCGCAAACCATGAATAAGCAGATGCAGAGTGAAGTGGGTAAGTATCAGGCAATGATTAAATCGACTATCCA
ACGTAATTTGGTAGTGGATGAATCTATGCGTGGCAAGACTTGTACTGTCTCTGTACGATTAGCAAATGATGGTTTTGTGA
TCAGCAGTCAAACTAAAGGCGGTGATCCTAACGTTTGTCGTGCAGCAAAAGCAGCGATTTTGAAGGCGGGTAAATTGCCA
GTGTCTCCGGACCCTGCAGTTTATAACTTGATGAAAGAAATTAACTTAATCGTTGAACCAACGTTTTAA

Upstream 100 bases:

>100_bases
AAATATTCCTTACGATAAAGTGATTCAGTTGATGGTGACCTTGCAAGGTGCTGGCGTGCCATCAGTCGGTTTGATGACGG
ATTCACCCAAGGAGAAATAG

Downstream 100 bases:

>100_bases
TTAAAGGAGTCCCATGAGAATATTGGCAAAATGGTTAGCATTGGCAGTTCTGCTGTGCACCACCCCCGCAAAAGCGGCAT
TGGATATTGTGATCACAGAA

Product: TolA family protein

Products: NA

Alternate protein names: LA Protein; LA-Like Protein; Protein lA; And Transport-Associated Protein lA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MADKSDVTLPLSISAGIHIGVIIILALGIDFSHKPEPMQQVSAPAVKAVMVDQQKVANQVEKLKQEKRDAERREQERQAE
LERKAQEAKQAREREQAQIKQLEQERKQQEIETQKANEATKLAQVKQQQEKEKAVKAEADRKLKEQERKVAEDAAQKAAE
KRKVEEAAAAKAESDRKLKEAEAKAKAEKAKADADAKAEAKAKAKADAKAKADAKAKADAEAKARAQQEQEMADALAAEQ
AALSQTMNKQMQSEVGKYQAMIKSTIQRNLVVDESMRGKTCTVSVRLANDGFVISSQTKGGDPNVCRAAKAAILKAGKLP
VSPDPAVYNLMKEINLIVEPTF

Sequences:

>Translated_342_residues
MADKSDVTLPLSISAGIHIGVIIILALGIDFSHKPEPMQQVSAPAVKAVMVDQQKVANQVEKLKQEKRDAERREQERQAE
LERKAQEAKQAREREQAQIKQLEQERKQQEIETQKANEATKLAQVKQQQEKEKAVKAEADRKLKEQERKVAEDAAQKAAE
KRKVEEAAAAKAESDRKLKEAEAKAKAEKAKADADAKAEAKAKAKADAKAKADAKAKADAEAKARAQQEQEMADALAAEQ
AALSQTMNKQMQSEVGKYQAMIKSTIQRNLVVDESMRGKTCTVSVRLANDGFVISSQTKGGDPNVCRAAKAAILKAGKLP
VSPDPAVYNLMKEINLIVEPTF
>Mature_341_residues
ADKSDVTLPLSISAGIHIGVIIILALGIDFSHKPEPMQQVSAPAVKAVMVDQQKVANQVEKLKQEKRDAERREQERQAEL
ERKAQEAKQAREREQAQIKQLEQERKQQEIETQKANEATKLAQVKQQQEKEKAVKAEADRKLKEQERKVAEDAAQKAAEK
RKVEEAAAAKAESDRKLKEAEAKAKAEKAKADADAKAEAKAKAKADAKAKADAKAKADAEAKARAQQEQEMADALAAEQA
ALSQTMNKQMQSEVGKYQAMIKSTIQRNLVVDESMRGKTCTVSVRLANDGFVISSQTKGGDPNVCRAAKAAILKAGKLPV
SPDPAVYNLMKEINLIVEPTF

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. Also Involved In The Translocation Of Bacteriophage DNA. [C]

COG id: COG3064

COG function: function code M; Membrane protein involved in colicin uptake

Gene ontology:

Cell location: Type II Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37497; Mature: 37366

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKSDVTLPLSISAGIHIGVIIILALGIDFSHKPEPMQQVSAPAVKAVMVDQQKVANQV
CCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKLKQEKRDAERREQERQAELERKAQEAKQAREREQAQIKQLEQERKQQEIETQKANEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLAQVKQQQEKEKAVKAEADRKLKEQERKVAEDAAQKAAEKRKVEEAAAAKAESDRKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKAKAEKAKADADAKAEAKAKAKADAKAKADAKAKADAEAKARAQQEQEMADALAAEQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHH
AALSQTMNKQMQSEVGKYQAMIKSTIQRNLVVDESMRGKTCTVSVRLANDGFVISSQTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEECCCCC
GDPNVCRAAKAAILKAGKLPVSPDPAVYNLMKEINLIVEPTF
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADKSDVTLPLSISAGIHIGVIIILALGIDFSHKPEPMQQVSAPAVKAVMVDQQKVANQV
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKLKQEKRDAERREQERQAELERKAQEAKQAREREQAQIKQLEQERKQQEIETQKANEAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLAQVKQQQEKEKAVKAEADRKLKEQERKVAEDAAQKAAEKRKVEEAAAAKAESDRKLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKAKAEKAKADADAKAEAKAKAKADAKAKADAKAKADAEAKARAQQEQEMADALAAEQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHH
AALSQTMNKQMQSEVGKYQAMIKSTIQRNLVVDESMRGKTCTVSVRLANDGFVISSQTKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEECCCCC
GDPNVCRAAKAAILKAGKLPVSPDPAVYNLMKEINLIVEPTF
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA