Click here to switch to the map view.

The map label for this gene is tolQ [H]

Identifier: 126173972

GI number: 126173972

Start: 2028466

End: 2029152

Strand: Direct

Name: tolQ [H]

Synonym: Sbal_1743

Alternate gene names: 126173972

Gene position: 2028466-2029152 (Clockwise)

Preceding gene: 126173971

Following gene: 126173973

Centisome position: 39.56

GC content: 42.5

Gene sequence:

>687_bases
GTGCAAGCTGATATGTCGATTGTTGGGTTATTTTTACAAGCCAGTTTATTAGTGAAATTTGTTATGTTCACCTTACTTTG
CTTGTCAGTGATGTCTTGGACGGTGATTTTACAACGCCGTAGCTTACTGACATCCGCAAAAAGTAAATCGGCGAAGTTTG
AAGACAAATTTTGGTCAGGCGTTGATTTAAACCGTTTATATAAAGAATTATCGACTCGTCCTGATAATAGCGGTTTAGAG
TCATTATTTGTGACTGGCTTTAAAGAATATTCACGCCTGAATAAATTAAATAGCAAAGTGCCCGATGCCGTGATGGACGG
TACATCACGTGCGATGCGTGTGACACTTTCTCGCGAAATGGAAAAGTTAGAAGCTAACTTACCCTTATTCGCGACCATTG
GTTCGACTAGCCCTTATATCGGTTTATTTGGTACGGTATGGGGGATTATGAATTCATTTATCGCCATTGGTTCGATGGAA
AACGCGACCTTAGCTATGGTTGCCCCCGGTATTGCTGAAGCCTTGATTGCAACGGCTATGGGTCTATTTGCTGCGATCCC
TGCGGTTATTGCGTACAACCGTTTCTCGACTCAAGTCGATAAATTGGAAATGGCCTACGCAAACTTTATGGAAGAGTTCT
CCAGCATTTTGCATCGCCAAGCATACAGTGAGAAGGAAGGGGCATAA

Upstream 100 bases:

>100_bases
GGAGACTGTTATTGTGAAGGCACAGTGCTGGTTGTTTGTGTTGCGCTGTCACGAATGCGTCCCCGAGCTATTCCCTTAAA
TATTGTGCAGGAGTTTGACA

Downstream 100 bases:

>100_bases
TGCAACCAGCTTATCAGCGCAAACGTCGTCGCCCCGTTGCCGAAATCAACGTGGTGCCCTATATCGACGTGATGCTCGTG
CTGTTAATTATTTTTATGGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQADMSIVGLFLQASLLVKFVMFTLLCLSVMSWTVILQRRSLLTSAKSKSAKFEDKFWSGVDLNRLYKELSTRPDNSGLE
SLFVTGFKEYSRLNKLNSKVPDAVMDGTSRAMRVTLSREMEKLEANLPLFATIGSTSPYIGLFGTVWGIMNSFIAIGSME
NATLAMVAPGIAEALIATAMGLFAAIPAVIAYNRFSTQVDKLEMAYANFMEEFSSILHRQAYSEKEGA

Sequences:

>Translated_228_residues
MQADMSIVGLFLQASLLVKFVMFTLLCLSVMSWTVILQRRSLLTSAKSKSAKFEDKFWSGVDLNRLYKELSTRPDNSGLE
SLFVTGFKEYSRLNKLNSKVPDAVMDGTSRAMRVTLSREMEKLEANLPLFATIGSTSPYIGLFGTVWGIMNSFIAIGSME
NATLAMVAPGIAEALIATAMGLFAAIPAVIAYNRFSTQVDKLEMAYANFMEEFSSILHRQAYSEKEGA
>Mature_228_residues
MQADMSIVGLFLQASLLVKFVMFTLLCLSVMSWTVILQRRSLLTSAKSKSAKFEDKFWSGVDLNRLYKELSTRPDNSGLE
SLFVTGFKEYSRLNKLNSKVPDAVMDGTSRAMRVTLSREMEKLEANLPLFATIGSTSPYIGLFGTVWGIMNSFIAIGSME
NATLAMVAPGIAEALIATAMGLFAAIPAVIAYNRFSTQVDKLEMAYANFMEEFSSILHRQAYSEKEGA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=224, Percent_Identity=58.9285714285714, Blast_Score=283, Evalue=5e-78,
Organism=Escherichia coli, GI1789381, Length=222, Percent_Identity=37.3873873873874, Blast_Score=123, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25179; Mature: 25179

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADMSIVGLFLQASLLVKFVMFTLLCLSVMSWTVILQRRSLLTSAKSKSAKFEDKFWSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
VDLNRLYKELSTRPDNSGLESLFVTGFKEYSRLNKLNSKVPDAVMDGTSRAMRVTLSREM
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
EKLEANLPLFATIGSTSPYIGLFGTVWGIMNSFIAIGSMENATLAMVAPGIAEALIATAM
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHH
GLFAAIPAVIAYNRFSTQVDKLEMAYANFMEEFSSILHRQAYSEKEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQADMSIVGLFLQASLLVKFVMFTLLCLSVMSWTVILQRRSLLTSAKSKSAKFEDKFWSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
VDLNRLYKELSTRPDNSGLESLFVTGFKEYSRLNKLNSKVPDAVMDGTSRAMRVTLSREM
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHH
EKLEANLPLFATIGSTSPYIGLFGTVWGIMNSFIAIGSMENATLAMVAPGIAEALIATAM
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHH
GLFAAIPAVIAYNRFSTQVDKLEMAYANFMEEFSSILHRQAYSEKEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]