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The map label for this gene is ppiD [H]

Identifier: 126173842

GI number: 126173842

Start: 1879343

End: 1881208

Strand: Direct

Name: ppiD [H]

Synonym: Sbal_1608

Alternate gene names: 126173842

Gene position: 1879343-1881208 (Clockwise)

Preceding gene: 126173841

Following gene: 126173851

Centisome position: 36.65

GC content: 46.73

Gene sequence:

>1866_bases
ATGTTAGAAAAGATCCGCGATGGTTCGCAAGGCTTGATTGCTAAAGGCATTCTCGTACTTGTGATTTTATCTTTTGCATT
TGCAGGAGTCAGCAGTTACTTAGGTTCTACAACTGATGTGCCTGCAGCAGAAGTGAACGGTGACATAATCACTAAAGCCG
AGCTTGAGCAGGCTTACCAAAGCGAGCGCTCTCGTATGGAGCAACAGCTAGGTGAGATGTTTGCTGCGTTATCTGCTGAC
GAAAAATATCTACAAAGCATTAAGCAGAGCGTATTAGAGCGCTTAGTGGCTGACAAACTGATTGATCAAGCTGCTAAGGC
TATGGGGTTGCGTGTATCTGACGAACAGATCATTGCAGCCGTGAAAACTGAACCTGCATTCCAAACCGATGGCAAATTTG
ATAACGATCGTTATCAAGCGATTCTACGTCAGTTAGGTTATCAACCACAGGCGTTCAGAGACATGATGCGCGTCGATATG
ACCCGTCGTCAGTTAACGGCTGCGCTTGTTGGTACTGAATTTGTGTTAGCTGGCGAAGCTAAGCAGTTAGCTGAGTTACA
AGGCCAAACCCGCGATGTTCGTTATTTAGTCGTTGATTCTGCGCCATTCTTAGCGACAGCGGTTGTGACTGACGAGCAAG
TGAAAAACTATTACGACGCAAACCAAGGGCAGTTTATGAGCCCTGAAATGGTGAGCTTAGAATATGTTGAGCTGAATGCG
GCTGATTTTGCTAAAAATAACCCAGTTTCAGACGAAGAAGCGCAAGCTTATTACGAAGAACACAAAGCGCAATACGTGTC
TAACGAGAAGCGTCTTGCCGCACACATTCTGGTTATGCCAGGTAGTGATGAAGCGGCTGCAAAAGCCAAGGCTGAAGATT
TAGCGAAGCAATTAGACAGCGGTGCCGATTTTGCTGATCTGGCTAAAGCGAACTCTGACGATACCTTGAGTGCAGAGCAG
GGCGGTAAACTGGATTGGTTTGAACCAGGTGTGATGGACCCCGCTTTCGATGCTGCATTATTTGCATTGAACAAAGGTCA
ACATTCTGCGGTGGTTAAAACTGACTTTGGTTTCCACATTATCAAGCTATTAGATGTGCAACCGGGTGTGACTGTACCGT
TTGCCGATGTGAAAGCTAAGATAGTAGCGCAATTGCAAGATAAGAAAGCGGTTGATCAGTTCTACAGCTTACAAAGCAAA
TTGGCTGATACTAGCTATGAAGTGCCAGATACACTATCTGAAACTGCTAAAGCTGTGGGCGTCGACATTAAGACGACTCC
ACTGTTCTCTCGCGATAACGTTCCTGCAGCGCTGAACAAGCCTGACTTAGTCAAAGCTGCGTTCTCTGAAACTGTTATGC
TAAAAGGGTTAAACAGTGAAGTGATTGAGCTTGAACCTAACCACGTGGTGGTGGTGCGTGTGAAGGAACATCACGATGCG
GGCACTTTGGCCTTAGCGGAAGTGAAAGCCAATATCGCCGAACGTTTGAAGCAAGATCAAGCAAACGAAGCTGCCCGTGC
GAAAGCACAAGAGCTGATGGCACAAGTTAAAGCCGGTGCAACGGATCTTGGTTTAGTGGCTAAAGCGAAACTAGGCCGCG
GCGCGCAAGATGTTGATGCTGCGATTGTAGGCAAAGCGTTCCAAATGCCAACACCAAGCACTTCTCCAGTTGTCGATACC
GTGGGTTTAGCAAATGGTTATGCCGTGGTTGCGCTAGATAAAGTCAACGCTGCTGAAGGTGTGAGTGATGAGCTGGTTAA
TGCGCTTAAACAACGCCTGAATGCTCAATACAGCGAAGCAGACTACCGTGGCTTGATAGATTCACTTAAAGCCAATGCCA
AGGTGCTTTACCCTGTAGAAGAATAA

Upstream 100 bases:

>100_bases
ACCAGTGGTAGCGTCTGAATATTCCCCATAAATTACAGAAAGGCGCATCTCAAACTGATGCGCCTTTTTATTTTGTTAAT
CGCAACAAGCGAGAAATCTG

Downstream 100 bases:

>100_bases
TTTAAGTGAGGATAGCGCGTTGAACTGGCTACCCTACTAGTAAACTTCGATTAAAAAGGCCAAGTGATTTCACTTGGCCT
TTTTGTTTTTCAATGCGATG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLEKIRDGSQGLIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGATDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE

Sequences:

>Translated_621_residues
MLEKIRDGSQGLIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGATDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE
>Mature_621_residues
MLEKIRDGSQGLIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQSERSRMEQQLGEMFAALSAD
EKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAAVKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDM
TRRQLTAALVGTEFVLAGEAKQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDSGADFADLAKANSDDTLSAEQ
GGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHIIKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSK
LADTSYEVPDTLSETAKAVGVDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGATDLGLVAKAKLGRGAQDVDAAIVGKAFQMPTPSTSPVVDT
VGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEADYRGLIDSLKANAKVLYPVEE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=631, Percent_Identity=33.122028526149, Blast_Score=341, Evalue=8e-95,
Organism=Escherichia coli, GI1786238, Length=328, Percent_Identity=30.1829268292683, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67256; Mature: 67256

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIRDGSQGLIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEHHHHHHHHH
SERSRMEQQLGEMFAALSADEKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDMTRRQLTAALVGTEFVLAGEA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCH
KQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECH
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
GADFADLAKANSDDTLSAEQGGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHI
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEE
IKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSKLADTSYEVPDTLSETAKAVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
CCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEEEECCCCC
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGATDLGLVAKAKLGRGAQDVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
AIVGKAFQMPTPSTSPVVDTVGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCH
DYRGLIDSLKANAKVLYPVEE
HHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MLEKIRDGSQGLIAKGILVLVILSFAFAGVSSYLGSTTDVPAAEVNGDIITKAELEQAYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEHHHHHHHHH
SERSRMEQQLGEMFAALSADEKYLQSIKQSVLERLVADKLIDQAAKAMGLRVSDEQIIAA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VKTEPAFQTDGKFDNDRYQAILRQLGYQPQAFRDMMRVDMTRRQLTAALVGTEFVLAGEA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCH
KQLAELQGQTRDVRYLVVDSAPFLATAVVTDEQVKNYYDANQGQFMSPEMVSLEYVELNA
HHHHHHCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECH
ADFAKNNPVSDEEAQAYYEEHKAQYVSNEKRLAAHILVMPGSDEAAAKAKAEDLAKQLDS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHC
GADFADLAKANSDDTLSAEQGGKLDWFEPGVMDPAFDAALFALNKGQHSAVVKTDFGFHI
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEE
IKLLDVQPGVTVPFADVKAKIVAQLQDKKAVDQFYSLQSKLADTSYEVPDTLSETAKAVG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
VDIKTTPLFSRDNVPAALNKPDLVKAAFSETVMLKGLNSEVIELEPNHVVVVRVKEHHDA
CCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEEEECCCCC
GTLALAEVKANIAERLKQDQANEAARAKAQELMAQVKAGATDLGLVAKAKLGRGAQDVDA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
AIVGKAFQMPTPSTSPVVDTVGLANGYAVVALDKVNAAEGVSDELVNALKQRLNAQYSEA
HHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCH
DYRGLIDSLKANAKVLYPVEE
HHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]